--- version: '1.0' entity: 'hgnc.symbol:' term: Organ Sex Age ordered: false label: '{entity} is differentially expressed in {term}' source: https://maayanlab.cloud/Enrichr --- Adipose - Subcutaneous Female 60-69 Up ACER2 ACKR2 ADAMTS5 ADCY4 ADGRL4 ADH1B ADRA2A AFAP1L1 AGPAT2 AGTR1 AIFM2 AKR1C2 ANGPTL2 APOL3 APOLD1 AQP7 ARHGAP20 ARHGEF15 BMP6 BTNL9 C19ORF12 CD248 CD300LG CD36 CDH5 CIDEC CLDN5 CLEC14A CLEC3B CPM CYGB DEFB132 DOCK11 EBF1 EBF3 EDN1 EGFL6 ELMOD3 FABP4 FAM124B FAM89A FGD5 FZD4 GALNT15 GFRAL GPC3 GPD1 GPR146 GYG2 INHBB ITGB1BP1 ITIH5 KCTD12 KLB LEP LIPE LRRC8C LVRN MEOX1 MGLL MMRN2 NEDD9 NMT2 NOTCH4 NXNL1 PALMD PECAM1 PLIN1 PLIN2 PLIN4 PML PNPLA2 PPARG PRKAR2B PTPRM RAPGEF3 RDH5 RETSAT RNF125 S1PR1 SASH1 SEMA3G SIK2 SLC19A3 SLC29A4 SMIM3 SPAAR SRPX2 STAT5A SYNE3 TACR1 TGFBR3 TIMP3 TIMP4 TNMD UVRAG VKORC1L1 VWF WNT11 ZNF366 Muscle - Skeletal Female 60-69 Up ABLIM2 ACTN2 ALPK3 AMPD1 ANKRD23 ASB16 ASB8 BEST3 BIN1 BTBD1 C10ORF71 CACNA1S CACNG1 CACNG6 CALML6 CAND2 CAP2 CAPN3 CAV3 CHMP1B CHRNA1 CHRNA10 CHRNB1 CLCN1 CLTCL1 CMYA5 CORO6 DCAF6 EEF1A2 EGLN1 EYA4 FEM1A FHL3 FXR1 GAMT GMPR IP6K3 ITIH6 JPH1 JSRP1 KCNA7 KCNJ11 KLHL30 KLHL40 KLHL41 LBX1 LMOD3 MACROD1 MAMSTR MAPK12 MYBPC1 MYF6 MYLK2 MYO18B MYOZ1 MYPN NEB OBSCN OPTN PCNT PDE4DIP PDLIM3 PFKM PHKG1 PITX3 PRKCQ PROB1 PYGM RAD23A RAPSN RBM24 RNF123 RPL3L RYR1 SGCA SH3BGR SIX1 SIX4 SLC29A2 SMTNL1 SMTNL2 SPTB SRPK3 STAC3 SYPL2 TBX15 TMOD4 TNNC1 TNNI1 TNNT1 TRIM54 TRIM72 TTN TXLNB UBAC1 USO1 USP13 USP54 USP6 YBX3 Artery - Tibial Female 60-69 Up ACAN ACTA2 ACTN4 ADARB1 ADIRF AMIGO2 ARHGEF17 ARHGEF39 ATL3 ATP10A BCAM C11ORF96 C1QTNF1 C1QTNF7 CCDC3 CHSY3 CLIC4 COL14A1 COL18A1 COMP CPED1 CRLF1 CRTAC1 CSPG4 CSRP2 DACT3 DSTN EFHD1 FBXL3 FHL5 FOXC1 FOXC2 FOXL1 FRY HAUS7 HDX HEY2 HTR1B ID2 IGFBP7 ITGA5 JAG1 JAK2 KCNA5 KCNAB1 KCTD10 KLHL26 LMOD1 LPP MAP7D3 MBNL1 MCAM MEF2D MSRB3 MUSTN1 MYO1D NBEAL1 NKD1 NOTCH3 NTF3 NTRK3 P2RX1 PDE4C PLEKHG3 PLS3 PRDM16 PRELP PRKG1 RASL12 RBPMS RCAN2 RERGL RHOB RNF180 ROCK1 ROR1 SDK1 SH3BGRL SH3RF3 SHOX2 SMAD7 SMURF1 SORBS2 SPEG SPOPL SUN2 SUSD5 TASP1 TBX18 TBXA2R TMEM181 TMEM47 TMTC1 TNS1 TRABD2B TSC22D1 UBA2 WTIP ZBTB16 ZFHX3 Artery - Coronary Female 60-69 Up AEBP1 ANTXR1 ARL4AP5 ART4 ASPN ATP10A BGN C1QTNF1 CARMIL1 CCDC190 CCDC3 CD151 CFH COL14A1 COL18A1 COL21A1 COL4A2 COL4A4 CPED1 CPXM2 CRIP1 CTPS1 DUXA ECM2 EFEMP1 ENPP4 FBLIM1 FMOD FOXS1 FRK GPR20 HAPLN1 HAUS7 HEYL IGFBP7 ITGA10 ITGA8 JADE1 KALRN KCNA5 KCNK15 KCNT2 LGR6 LRRC17 LTBP1 LTBP2 MCAM MEGF6 MFAP4 MFGE8 MMP23B MSC MTHFD1L MYO1D NT5DC2 NTF3 NTRK3 OGN OMD PCDHB16 PCOLCE2 PDGFA PPP1R14A PRKG1 PTGIS S1PR3 SCARF2 SMIM10 SORT1 SPARCL1 ST6GAL2 SUSD5 TAGLN TBX18 TBX2 TBXA2R TGM2 THBS2 TIMP1 TNFRSF11B TRABD2B VCAN Heart - Atrial Appendage Female 60-69 Up ACTC1 ADAMTS7 ADAMTSL2 ADGRD1 ALPK2 ANKRD1 ASPG BAMBI BCO2 BMP10 CASQ2 CCDC141 CHRNE CIB2 CORIN CPNE5 CRIP2 CYP2J2 DAND5 DHRS7C DKK3 DOK7 EIF1B FABP3 FAM216B FBXO40 FGF12 FITM2 GATA4 GRXCR2 HCN4 HHATL HRC HSPB2 HSPB3 HTRA3 IGSF5 ITGB1BP2 KCNIP2 KLHL31 KRBA1 LAPTM4B METTL7B MYBPC3 MYBPHL MYH6 MYH7B MYL4 MYL7 MYLK3 MYOZ2 MYZAP NDUFAB1 NEBL NES NKX2-5 NKX2-6 NMRK2 NPPA NPPB NRTN OR10P1 OTOGL PAM PCOLCE2 PLA2G5 POPDC2 PPARGC1A PRKAG2 PRR32 PXDNL RABGAP1L RBM20 RBPMS2 RD3L RILPL1 RNF207 RYR2 SBK2 SBK3 SCN5A SHD SLC25A4 SLC41A1 SLC4A3 SLC8A1 SSTR5 SYNPO2L TBX20 TBX5 TECRL TMEM182 TNNI3K TNNT2 TRIM55 TSPAN18 UQCRB USP28 WASHC2A WNK2 Adipose - Visceral (Omentum) Female 60-69 Up AADACL4 ABCB5 ADGRL4 AGPAT2 ALDH1A3 ALOX15 BTNL9 CD36 CLDN15 FOSB GAS1 GFPT2 GPBAR1 GYG2 HAS1 HBEGF ITLN1 LRRN4 LXN LYVE1 MMP19 MSLN MUC16 PDPN PNPLA2 PPARG PROCR PRRT4 RARRES1 SERPINE3 SLC7A10 SOCS3 SOX17 SPAAR SPRY1 SRPX TIMP4 TMEM88 TSHZ2 UPK3B WNT11 Uterus Female 60-69 Up ACSM3 ADAM33 ADAMTS19 ADGRG4 ALDH1A2 AR ATP8B4 B3GLCT BNC2 BTBD19 CAPN6 CCDC171 CDH24 CIC CLEC4F DCHS1 DET1 EBF4 EMX2 EPHB4 ESR1 FOXO6 FRMD7 GATA2 HAUS5 HOXA10 HOXA11 HOXA6 HOXD10 HOXD11 HOXD3 HOXD4 HOXD8 HOXD9 IGFBP5 IL17RD INTS11 ISLR ISOC1 KCNAB3 KCNG1 KLHL13 LCN10 LEFTY2 LINGO2 LONRF2 MATN1 MEIS1 MEIS2 MEIS3 MUS81 MYO15B NLGN2 NXNL2 OR10R2 OSR2 PBX1 PCDHB15 PCDHB7 PGR PLEKHH2 PLXDC1 POMGNT2 PRLR PTGER3 PTK7 RAD51B RAMP1 RAP2C RAX2 RERG RPRM RSPO1 SERTM1 SLC24A3 SLC37A3 SLC5A4 SMO SPACA6 SPEF2 STK26 SULF2 SUPT20HL1 SUPT20HL2 SYTL4 TAS2R20 TBC1D1 TBL1X TCF23 TEX15 TMEM200B TNFAIP8L3 TRPC4 TUBE1 TULP1 WT1 XKR5 ZBTB12 ZNF333 ZNF516 Vagina Female 60-69 Up AADACL4 ADAM33 ADAMTSL5 ALOX12 AR BMP4 CGNL1 CPA6 CYP27C1 DIO3 EDN2 EDN3 EDNRA ESR1 EVX1 FABP5 FBLN1 FGF10 GABRE GDF7 GLIS1 GSTM2 HCG22 HOXA13 HOXD10 HOXD11 HOXD12 HOXD13 HOXD9 HPGD HPSE2 ISL1 LPAR6 MASP1 MATN1 MATN2 MMP10 NUAK2 NXNL2 OSR2 PI16 PLA2G4D PRSS12 RSPO1 SALL3 SERPINB13 SERPINB3 SERPINB4 SFRP1 SOX7 SPINK6 TMPRSS11A TMPRSS11D TMPRSS11E WNT2B Breast - Mammary Tissue Female 60-69 Up ABCB5 ADGRD2 ALX4 ANO1 ARHGEF38 BTNL9 CCL28 CD300LG CITED4 CLDN8 CMTM7 CX3CL1 CYP4Z1 ELF3 ELF5 GABRP GSC HCAR1 IL22RA2 INHBB IRX1 IRX2 IRX5 KIT KRT17 LAMC2 LMX1B MRGPRX3 MRGPRX4 OXTR PLEKHS1 SCGB1D2 SCGB2A2 SCUBE2 SFRP1 SLC28A3 SPAAR STAC2 TBC1D9 TFAP2B TNN TRPS1 VGLL1 VTCN1 Skin - Not Sun Exposed (Suprapubic) Female 60-69 Up AADACL2 ABCA12 ADGRF2 ADGRF4 ALOX12B ANXA8L1 ARSF ATP6V1C2 BNIPL BPIFC C3ORF52 CAPNS2 CARD18 CASP14 CCL27 CDHR1 CDX4 CLDN1 CLEC2A COL17A1 COL7A1 DEGS1 DLX5 DMKN DSC3 ELOVL4 ETV3 EXPH5 FAM83B GAL3ST4 GAN GATA3 GJB3 GJB4 HOPX HS3ST6 IFFO2 IL20RA IL20RB IL37 IRF6 IRX3 KCNK7 KLC3 KLF4 KRT1 KRT14 KRT23 KRT77 KRT80 KRTDAP KY LAMB4 LGALSL LIPK LIPM LY6G6C LYPD6B MFSD2A MYCL NECTIN4 NIPAL4 NKPD1 NR1D1 OR10A6 OR5P2 OR5P3 OVCH2 PGLYRP4 PLA2G4F PNPLA1 POU2F3 PPP1R14C RDH12 RNF39 RORA SBSN SDR9C7 SERPINB7 SLC10A6 SPINT3 SPTSSB STARD5 SYT8 TFAP2A TGM5 TINCR TMEM45A TNFRSF19 TNS4 TP63 TUFT1 VAV3 WEE1 WFDC5 WNT16 WNT3 XG ZNF273 ZNF750 Minor Salivary Gland Female 60-69 Up AGFG2 ALDH1A3 ALX1 ANKRD36C ASCL3 ATP6V1B1 ATP6V1C2 AZGP1 BARX2 BPIFB2 BPIFB6 CA13 CBR3 CCDC160 CCL28 CHST9 CLDN17 CLDN24 CLDN8 CRACR2A CRACR2B CRISP3 CXCL17 DEFB1 DNASE2B EHF ELF3 ELF5 ENPP3 FAM3D FBN3 FDCSP FOLR1 FUT2 GABRP GALNT4 GALNT6 GLYATL2 GPRC6A HTN1 IRX1 IRX2 KCNK5 KCNN4 KRT19 KRT3 KRT7 LCN2 LHX8 LOXL4 LPO LRRC26 LTF MLPH MMP27 MMP7 MPV17L MSGN1 MUC16 MUC19 MUC5B MUC7 NAALADL2 NKX2-6 ODAM OPRPN OTX1 PANX3 PAX3 PHLDA1 PIGR PIP PLEKHS1 PLPP2 PROM1 PRR4 RUNX1 RUNX2 SCNN1A SH3BP4 SLC4A11 SLITRK6 SLPI SMR3A SOX9 STATH STK39 SVOPL TCN1 TFCP2L1 TGFB2 TMEM63A TNN TOX3 TRPV4 VGLL1 VTCN1 WFDC2 ZG16B ZNF552 Brain - Cortex Female 60-69 Up ADGRA1 ADGRB1 ADGRB2 ANKRD24 APC2 ATCAY BHLHA9 BRINP2 BRSK1 C1QL2 C2CD4C CABP1 CACNG3 CACNG7 CAMK1G CAMK2A CBLN2 CCK CHD5 CHRM1 CHST1 CHST10 CIT COL20A1 COL26A1 CTNNA2 CUX2 DAGLA DBNDD1 DOC2A DPF1 EIF4E1B ELFN2 EMX1 FAM107A FAM163B FAM81A FBXO41 FOXD4L6 FOXG1 FXYD7 GALNT8 GRIN1 HAPLN4 HECW1 HEPACAM HTR3B ITPKA KCNAB2 KCNH3 KCNH5 KCNJ4 KCNS1 KIF1A KIF5A KIF5C LCN15 LHX2 LINGO1 LRFN2 LRFN5 LYNX1 MCF2L2 MGAT5B MPPED1 NAGPA NCAN NRGN OLFM1 OPRD1 PACSIN1 PDE6H PHF24 PLEKHM2 PNMA3 PNMA6A PRKAR1B PTPRT R3HDM1 RAPGEF4 RGR RHBDL3 RIMS3 RNF208 RORB RTP1 SCG3 SHC3 SLC39A12 SNCB SNPH SNX32 SOHLH1 SYN1 TBR1 TESPA1 UNC13C UNC5A VSTM2L ZDHHC22 Adrenal Gland Male 50-59 Up AADAC ABCB1 ABCC3 ABCF3 ADGRV1 AKAP7 AKR1B1 ALAD ALAS1 AMHR2 AOX1 APOE AS3MT ASB4 C2CD2 C4B CELA1 CLRN1 CREBL2 CTNNAL1 CTSA CYB561A3 CYB5B CYP11A1 CYP11B1 CYP17A1 CYP21A2 DDB1 DEXI DHCR24 DLK1 DUSP16 EPHX1 FAM166B FAM43B FDX1 FDXR FNDC4 GALM GNPTG GNS GSTA1 GSTA3 GSTA4 HDHD3 HSD3B2 IDH1 IFITM10 KCNJ5 KCNK3 KCNN2 KCNQ1 KCTD14 KIAA1958 KLHL4 LONP1 LRRC61 MAP3K15 MAP3K5 MC2R MCOLN3 MGARP MRAP MRPL33 NR0B1 NR5A1 PAPSS2 PEBP1 PEX3 PLBD2 PORCN QPRT RARRES2 RBBP7 RDX RGN RMDN2 SCARB1 SEMA6A SERPINA5 SLC16A9 SLC23A2 SLC40A1 SLC47A1 SLC8B1 SNTB1 SOAT1 SREBF1 STAR TBC1D4 TBC1D8B TBX3 TKFC TM7SF2 TMEM150C TPD52L1 WHRN ZNF275 ZNF280A ZSWIM5 Thyroid Male 50-59 Up AFAP1L2 AMELY ATP13A4 BMP8A C16ORF89 CLN5 COL23A1 CPQ CRABP1 CRYGN CYTH2 DAPK2 DIO1 DIO2 DUOX2 EPOR EXOC3L2 FOXE1 FREM2 FSCN2 GAL3ST3 GFRA2 GOLGA8B GOLGA8M GOLGA8Q GRK1 HHEX HIRA HOOK3 IFT140 INPP5J IQCA1 IVD IYD KATNAL2 KCNC3 KCNJ16 KLHL14 LCN12 LIPG LIPI LPCAT2 LRP2 MARVELD2 MBD6 MGAT4C MMP15 MPPED2 MROH1 MT1F MUC15 NKX2-1 NPNT OR2T8 PAX8 PBX4 PDE8B PKHD1L1 PLA2G6 PLA2R1 PLEKHG4B PLEKHH1 PLVAP PRTG RCBTB1 RECQL5 RGL3 RHPN1 RTN4RL2 S100A5 SALL1 SALL4 SCX SHISA2 SLC12A8 SLC16A11 SLC25A29 SLC26A4 SLC26A7 SLC4A11 SLC4A5 SLC5A8 SNX22 SUCNR1 TBL1Y TCERG1L TFF3 TG TLE6 TMEM30B TPMT TPO TSHR WDR72 ZBED2 ZNF114 ZNF486 ZNF737 ZNF804B ZNF90 Lung Male 50-59 Up A2M ABCA3 ACOXL ACP5 ACVRL1 ADAMTS8 ADGRF5 ADGRL2 AGER AGTR2 ANKRD29 ATP11A BMP5 C20ORF202 CACNA2D2 CALCRL CASS4 CCDC102B CCL18 CEACAM6 CLEC1A COL6A5 COL6A6 COX4I2 CTSH DRAM1 EMP2 EPAS1 FCN3 FGFR4 FOLR1 GGTLC1 GPC3 GPRC5A HECW2 HIGD1B HTR3C HYAL2 ICAM1 IL15RA IL7R INMT KCNS3 LAMC3 LAMP3 LPCAT1 LRRN4 LTK MARCO MS4A15 MSR1 NAPSA NCKAP5 NDNF NKD2 OLR1 OR6K3 PALD1 PHEX PLEKHH2 PTPRB RAMP3 RBMS2 RGCC ROS1 RP1 RS1 RSPO4 RTKN2 SCGB3A2 SFTA2 SFTPA1 SFTPA2 SFTPB SFTPC SFTPD SHROOM4 SLC34A2 SLC39A8 SLC6A4 SLCO2A1 SLIT2 SMAD6 STARD8 SUSD2 TAL1 TBX2 TBX4 TCF21 TEK TFEC TFPI TMEM100 TMEM125 TMEM74B UNC13B VEGFD VIPR1 WNT2 WNT3A Spleen Male 50-59 Up ABI3 BANK1 BTN3A1 BTN3A2 BTN3A3 C1QA C1QB C1QC CABP4 CARD9 CCL14 CCL24 CCM2L CCR5 CD163L1 CD180 CD19 CD1C CD1D CD4 CD5L CD72 CD79B CD8A CDCP2 CERKL CNR2 CR2 CSF1R CXCL1 CXCL13 CXCL6 CXCR5 CXCR6 DNASE1L3 EMID1 EPHA8 EXOC3L1 FCRL1 FCRL2 FCRL3 FGD2 FHOD1 FLI1 GAB3 GDPD2 GDPD5 GIMAP1 GPR142 GPR182 GRAP GSDMD HLA-DOB HMOX1 HYAL1 HYAL2 IL10RA IL24 IRF8 ITGAD KAZALD1 KLRC1 LILRA4 LILRB1 LILRB5 LRTM1 MPEG1 MS4A7 MZB1 NLRC3 NOS3 NOX5 NPY1R NR5A1 OR2AJ1 OR5AK2 OR9G4 P2RX5 P2RY6 PARP15 PDE2A PDE6G PDLIM2 PRR5L PSTPIP2 RENBP SIGLEC12 SLC9A5 SPIC STAB1 STAB2 TAS1R3 TDGF1 TLX1 TMC8 TMEM26 TNFRSF13C TRAPPC3L TXK VCAM1 Pancreas Male 50-59 Up AMY1A AMY1B AMY1C AMY2A AMY2B ANXA4 AQP12A AQP12B AQP8 BHLHA15 CEL CELA2A CELA2B CELA3A CELA3B CFTR CHST4 CLDN10 CLPS CLPSL2 CPA1 CPA2 CPB1 CTRB1 CTRB2 CTRC CTRL CUZD1 EPB41L4B ERICH5 ERO1B ERP27 FAM3B FBXW12 FKBP11 G6PC2 GATM GCG GLP1R GNMT GP2 GPR119 GRPR GUCA1C HOMER2 IAPP IL22RA1 INS KCNK16 KIRREL2 KLK1 LENG9 LGALS2 LHFPL5 MNX1 NEURL3 NPHS1 NR5A2 ONECUT1 OR10G4 OR4D5 OR6M1 OR8D4 P4HB PDIA2 PDX1 PGGHG PKHD1 PLA2G1B PNLIP PNLIPRP1 PNLIPRP2 PRDX4 PRSS1 PRSS2 PRSS3 PTF1A RBPJL REG1A REG1B REG3G RNF186 RRBP1 SCTR SEL1L SERPINI2 SLC30A2 SLC30A8 SLC38A5 SLC39A5 SLC43A1 SLC4A4 SPINK1 SYCN TECPR1 TMED6 TMEM97 TPST2 TRPV6 XBP1 Esophagus - Muscularis Male 50-59 Up ABCC1 ACTG2 ADAMTSL1 ADCY5 ANKS1A ANTXR2 ARHGAP10 ARHGEF26 ARMC9 ARSB BCHE BTC CACNA1H CACNB2 CALD1 CCDC69 CHRM3 CNN1 CNTNAP3 CNTNAP3B COL4A5 COL4A6 CYSLTR1 DAAM2 DENND2A DGKG DHX35 DMPK DPYSL3 EML1 EPHA7 ERVFRD-1 FAM83D FBXO30 FGL2 FNBP1 FOXF1 FOXF2 FOXP1 GIPC3 GPC4 HLF HOXA4 HOXB2 HOXB4 HPSE2 IGSF9B JPH2 KANK2 KCNMB1 KCNQ4 KIAA0753 LHCGR LSM11 MYH11 MYL9 MYLK NKX6-1 NRP2 NTN1 PALLD PGM5 PLEKHO1 PPP1R12A PPP1R12C PRUNE2 PYGB RARB RBPMS RGMA RGMB RGS2 RSPO3 S1PR3 SCUBE1 SEMA3A SEMA3E SLC27A6 SLC2A12 SLITRK3 SMTN SORBS1 SYDE2 SYNM TOX2 TPBG TRPC6 TTC23 WLS ZNF503 Esophagus - Mucosa Male 50-59 Up A2ML1 ADH7 ALDH3A1 ANXA1 AQP3 BARX2 CALML3 CAPN1 CAPN14 CLCA2 CNFN CRABP2 CRNN CSTA CSTB CYSRT1 DSC2 DSG3 DYNAP ECM1 EMP1 EPGN EPHA1 EPHA2 ERO1A ESPL1 EVPLL FABP5 FAM110C FAM83A FAM83H FGFBP1 GBP6 GIPC1 GJB2 GNA15 GPR78 GSTP1 IL1RN KLK10 KLK12 KLK13 KRT13 KRT15 KRT4 KRT6A KRT6B KRT6C LEXM LY6D MAL MALL MPZL2 MUC21 NMU OTOP3 PADI1 PAX9 PITX1 PPL PRSS22 PRSS27 RAET1E RAET1L RHCG RHOD RIPK4 RNF223 S100A14 S100A16 S100A2 S100A8 SERPINB13 SERPINB3 SFN SIM2 SOX15 SPINK5 SPRR1A SPRR2A SPRR2D SPRR3 TBX6 TGM1 TGM3 TMEM184A TMEM40 TMPRSS11A TMPRSS11B TMPRSS11D TMPRSS4 TRIM16 TTC22 TTC9 TTLL12 TXNDC17 UGT1A7 USH1G VSIG10L ZNF185 Esophagus - Gastroesophageal Junction Male 50-59 Up ADCY5 ANKS1A ANTXR2 BTC C1QTNF3 CACNA1H CACNB2 CHRM3 COL4A5 COL4A6 CYSLTR1 DEFB124 DENND2A DHX35 EML1 ERVFRD-1 FGL2 FOXF1 FOXF2 FOXP1 HOXA3 HOXA4 HOXB2 HOXB3 HOXB4 HPSE2 KCNMB1 KCNQ4 MAS1L MEIS1 MRGPRF MS4A2 MYH11 MYOC NKX6-1 NRP2 NTN1 P2RX2 PPP1R12C RBPMS RGMB RSPO3 SEMA3A SEMA3E SIGLEC6 SMTN SYNM WLS Stomach Male 50-59 Up A4GNT ADAM28 AGR2 AKR1B10 AKR7A3 AKR7L ALDH1A1 AMACR ANKRD22 ANXA10 ARL14 ATP4A ATP4B B3GNT3 B4GALNT3 BAIAP2L1 BARX1 C9ORF152 CA2 CA9 CAPN13 CAPN8 CAPN9 CCKAR CCKBR CHIA CLDN18 CLIC6 COL2A1 CTSE CXCL17 CYP2S1 CYSTM1 DAZ1 DUOXA2 EPN3 ESRRG FER1L6 FMO5 FOXA2 FOXA3 FOXQ1 FRMD1 FUT1 GALE GBGT1 GCNT4 GHRL GKN1 GKN2 GPER1 GPR155 GPRC5C KCNE2 KPNA7 LIPF LIPH MCIDAS MECOM MFSD4A MUC1 MUC5AC MUC6 MYH13 MYRF NBPF12 PALM3 PDILT PGA3 PGA4 PGA5 PGC PIK3C2G PSCA PTGDR2 RASSF6 RFLNA RFX6 S100P SLC26A9 SLC4A2 SLC5A5 SLC9A1 SLC9A2 SLC9A4 SULT1C2 TFF1 TFF2 TMED6 TMEM92 TOX3 TPCN2 TRIM50 TRIM73 TRIM74 VILL VSIG1 VSIG2 VWA2 XYLT2 Adipose - Visceral (Omentum) Male 50-59 Up AADACL4 ADGRL4 ADIPOQ ALDH1A3 ALOX15 ANGPTL2 AQP7 ARHGEF15 AVPR2 BNC1 BTNL9 C1QTNF9 CD209 CD300LG CD36 CIDEA CLDN15 CPXM1 CYYR1 DLC1 DUSP6 F13A1 FABP4 FAM89A FGF10 FOLR2 GAS1 GFPT2 GNAT3 GNG11 GPIHBP1 GPR4 HAS1 IGF2 ITLN1 KDR LGALS12 LPL LRRN4 LXN LYVE1 MDFI MEST MMRN2 MSLN MUC16 NOTCH4 NR1H3 NWD2 PDPN PLTP PNPLA2 PPARG PRG4 PRKAR2B PROCR PROKR1 PRRT4 RARRES1 RBP7 RDH5 ROBO3 ROBO4 SERPINE3 SLC7A10 SOCS3 SOX17 SPAAR SPRY1 TIE1 TIMP4 TM4SF1 TM4SF18 TMEM88 TSHZ2 UPK1B UPK3B VWF WNT11 Skin - Not Sun Exposed (Suprapubic) Male 50-59 Up AADACL2 ABCA12 ACAD9 ACER1 ADGRF2 ADGRF4 ANKRD35 ANXA8L1 ARHGEF19 BNIPL BPIFC CALML5 CAPNS2 CARD18 CASP14 CCL27 CD207 CDHR1 CDX4 CENPP COL17A1 COL7A1 CPA4 CST6 DEGS1 DMKN DSC3 EFNA3 FAM83B FAM83C FOXN1 GAL3ST4 GAN GATA3 GJB3 GJB4 HR HS3ST6 IGFL2 IGFL3 IL20RA IL20RB IRX3 KCNJ18 KCNK7 KLC3 KLF4 KRT1 KRT10 KRT14 KRT77 KRT80 KRTDAP LGALS7 LGALS7B LGALSL LIPK LIPM LRIT2 LY6G6C LYPD6B NIPAL4 NKPD1 OR5P2 OR5P3 OVCH2 PARD6G PGLYRP4 PLA2G2F PLA2G4E PLA2G4F PNPLA1 POU2F3 RAB7B RDH12 SBSN SDR42E1 SDR9C7 SERPINB5 SLC39A2 SPTSSB STARD5 TFAP2A TFAP2C TGM5 THEM5 TINCR TMEM254 TMEM45A TNFRSF18 TNFRSF19 TP63 VANGL2 VAV3 WFDC5 WNT16 WNT3 WNT4 WNT7B ZNF273 Colon - Sigmoid Male 50-59 Up ACTG2 ATP2B4 BAG2 BMP3 BTC C3ORF80 CAB39L CACNA1C CACNA1H CCDC69 CCL11 CDK8 CHRM2 CNN1 COL24A1 CSRP1 DCP1B EML1 FBXL22 FOXF1 FOXP2 FXYD6 FZD7 GALR2 GDNF GJC1 GLB1L2 GLP2R GREM2 HAND1 HAND2 HDAC4 HOXA13 HOXB3 HOXD10 HOXD11 HOXD12 HOXD13 ILK KCNH2 KCNMA1 KCNQ4 KIZ KLHL23 LIMS2 LRCH2 LRIG1 LRRC3 MAB21L2 MASP1 MDM1 METTL24 MID1 MRGPRF MYH11 MYLK NKX2-3 NKX3-2 NPY4R NRP2 NT5DC3 NTSR1 NXN PBX3 PDE3B PDE9A PDZRN3 PDZRN4 PGM5 PHOX2B PLA2G2C PLA2G4A PLEKHO1 PNCK PTBP2 PTGFRN PTGS1 RAB23 RNF150 ROR2 SEMA3A SLC5A7 SMTN SPOP SSC5D STON1 STON1-GTF2A1L SYDE2 SYNM TACR2 TBC1D1 TEAD3 TES TGFB1I1 TMTC2 TNFAIP8L1 TSPAN11 TSPAN2 ZACN ZNF219 Small Intestine - Terminal Ileum Male 50-59 Up ACE ACSL5 ADAMDEC1 ADGRG7 ALPI AMN ANPEP ANXA13 AOC1 APOA4 APOBEC1 ATOH1 B3GALT5 BAIAP2L2 BCO1 BTNL3 BTNL8 C11ORF86 C17ORF78 CAPN13 CCL25 CCR9 CDHR2 CDHR5 CEACAM18 CEACAM20 CHST5 CLCA1 CLDN15 CPO DEFA5 DEFA6 DGAT1 DHRS11 DPEP1 ENPEP EPS8L3 ERICH4 FABP2 FABP6 FAM151A GALR2 GBA3 GUCA2A GUCA2B GUCY2C HKDC1 HNF4G ITLN2 KCNJ13 MALRD1 MEP1A MEP1B MISP MOGAT3 MS4A10 MS4A8 MTTP MUC17 MUC3A MYO1A MYO7B MYRFL NAALADL1 NLRP6 OAT PLCB3 PRAP1 RBP2 REG4 SI SLC10A2 SLC13A1 SLC13A2 SLC15A1 SLC17A8 SLC23A1 SLC23A3 SLC51B SLC52A1 SLC5A1 SLC5A9 SLC6A19 SLC6A20 SLC7A9 SMIM24 SPINK4 SULT1A2 TAS2R38 TBX10 TM4SF20 TM6SF2 TMEM150B TMEM253 TMEM92 TMIGD1 TREH TUBAL3 VIL1 XPNPEP2 Colon - Transverse Male 50-59 Up ANKS4B ATOH1 B4GALNT2 BCL2L15 BEST4 C15ORF48 CA1 CA2 CA7 CALML4 CAPN5 CASP6 CCL15 CDC42EP5 CDH17 CDX1 CDX2 CEACAM5 CEACAM7 CES3 CLDN3 CLDN7 CLRN3 DHRS11 DQX1 EFNA2 EPCAM EPS8L3 ERN2 ETHE1 FABP1 FAM83E FXYD3 FZD5 GAL3ST2 GALNT12 GCNT3 GPA33 GPR35 GUCY2C HEPACAM2 HHLA2 HOXA6 HOXB5 HOXB9 HSD11B2 HTR3E IHH ISX KRT20 KRT8 LEFTY1 LGALS4 LRRC19 LRRC31 LYPD8 MARVELD3 MISP MS4A12 MTMR11 MUC12 MYO7B NOX1 NPY4R NXPE1 NXPE2 NXPE4 OMP PHGR1 PIGR PIGZ PLA2G10 PLS1 PPP1R14D PRR15 PYY REP15 RXFP4 SATB2 SELENBP1 SLC26A2 SLC26A3 SLC44A4 SLC9A2 ST6GALNAC1 TMEM236 TMEM54 TPSG1 TRABD2A TRIM15 TRIM31 TRPM4 TSPAN1 TSPAN8 UGT1A10 UGT1A8 UGT2B17 URAD VIL1 ZG16 Prostate Male 50-59 Up ABCC4 ALDH1A3 AMD1 ANO7 AR ARG2 ARHGEF38 CDH26 CDYL2 CENPN CFAP69 CHRNA2 COL9A1 CPA6 CPAMD8 CPLX3 CPNE4 CREB3L4 EBF4 EPHA3 EVX1 EYA1 FAAH FEV FOLH1 FOXA1 GATA2 GCNT2 GLB1L2 GLB1L3 GLIS1 HOXA13 HOXB13 HOXD11 HOXD13 ISL1 ISM2 KLK2 KLK3 KLK4 LMAN1L MESP1 MKX MLPH MSMB NEFH NKX3-1 NPY NR2E3 NTF4 OR51C1P OR51E1 OR51E2 P4HA3 PAGE4 PAK1IP1 PDE11A PLPP5 POTEH POTEM PRAC1 PRAC2 PRDM8 PRIM2 RDH11 RFPL1 RFPL2 RLN1 RLN2 RPS4Y2 SCUBE2 SERPINB11 SHROOM1 SLC15A2 SLC30A4 SLC45A3 SORD SP8 SPDEF SRD5A2 STAC STEAP2 TBX3 TMCO4 TMEM141 TMPRSS2 TNFSF15 TRPM8 TRPV6 TTC6 TULP1 UPK3A USP43 XKR5 ZNF350 ZNF613 ZNF761 ZNF816 ZNF827 ZNF888 Testis Male 50-59 Up ACTL8 ANHX ASZ1 BTBD18 C18ORF63 C2ORF78 C5ORF47 CCDC172 CCDC73 CCNB3 COX6B2 CT47B1 CTCFL DAZL DCAF4L1 DCAF4L2 DDX4 DDX53 DMRTB1 DMRTC2 DPEP3 FAM9A FBXO47 FKBP6 FMR1NB FOXN4 FOXR1 FOXR2 FTHL17 GAGE1 GDPD4 HORMAD2 HSF2BP INCA1 KCTD19 MAEL MAGEA1 MAGEA10 MAGEA11 MAGEA12 MAGEA3 MAGEA4 MAGEA6 MAGEA8 MAGEB10 MAGEB4 MAGEB6 MAGEC1 MAGEC2 MAJIN MEIOB MEX3B MOV10L1 MPC1L NANOS2 OOEP OVOL3 PAGE1 PAGE2 PAGE2B PAGE5 PASD1 PRAME PRDM7 PRDM9 PRR23A PRR23B RBMXL3 RFPL3 RNF17 SMC1B SPANXB1 SPANXN4 SPANXN5 SPATA31C1 SPATA31C2 SSX1 SSX3 STK31 SYCP1 SYCP3 TDRD12 TERB1 TEX101 TEX13C TEX13D TEX19 TFDP3 TKTL1 TOPAZ1 TPRX1 TRIM60 USP26 VCX2 VCX3A XAGE5 ZCWPW1 ZNF541 ZNF560 ZNF99 Adipose - Subcutaneous Male 50-59 Up ADAMTS5 ADCY4 ADGRL4 ADH1B ADRA2A AFAP1L1 AGTR1 ANGPT4 ANGPTL2 ANGPTL5 APOL3 AQP7 ARHGAP20 ARHGEF15 ATP8B4 AVPR2 BMP6 CD300LG CD34 CD36 CFD CIDEC CILP CLDN5 CLEC14A CLEC3B CPXM1 CYGB DOCK11 EBF1 EBF3 ELMOD3 FAM124B FGD5 FOLR2 FZD4 GALNT15 GFRAL GGT5 GHR GNG11 GPC3 GPD1 GPR146 GSN HTR1F INHBB ITIH5 KCTD12 KRTAP13-4 LHX6 LIMA1 LIPE LRRC8C LVRN MEOX1 MFAP5 MMRN2 MYCT1 NEDD9 PDGFRB PECAM1 PLIN1 PLIN4 PNPLA2 PPARG PRRX1 RAMP2 REM1 RNF125 S1PR1 SASH1 SEMA3G SLIT3 SPRY1 STEAP4 SYNE3 TACR1 TGFBR3 TIMP3 TMEM132C TNMD UVRAG VWF WNT11 ZNF366 Muscle - Skeletal Male 50-59 Up ABRA ACTA1 ALDOA AMPD1 ANKRD23 ANKRD39 APOBEC2 ART1 ASB10 ASB12 ASB16 ASB2 ASB5 ATP1B4 ATP2A1 BIN1 C10ORF71 CACNA1S CACNB1 CACNG1 CACNG6 CAND2 CAP2 CAPN3 CASQ1 CAV3 CHRNA10 CHRNB1 CHRND CKM CLCN1 CMYA5 COQ8A CUTC DCAF6 DUSP13 EEF1A2 ENO3 FEM1A FHL3 FXR1 IDI2 JPH1 JSRP1 KCNA7 KCNJ11 KLHL41 LBX1 LMOD3 LRRC2 LRRC20 MACROD1 MAPK12 MYBPC1 MYBPC2 MYL1 MYO18A MYOT MYOZ1 MYPN NEB NFE2L1 NRAP NT5C1A OBSCN PDE4DIP PFKM PGM1 PHKG1 POPDC3 PPP1R27 PRKCQ PROB1 PYGM RAD23A RAPSN RNF123 RPL3L RPUSD4 RTN2 RYR1 SCN4A SMTNL2 STAC3 SYPL2 TCEA3 TMEM38A TMOD4 TNNC2 TNNI1 TNNT1 TPM3 TRDN TRIM54 TRIM72 TTN USP13 VGLL2 YBX3 YIPF7 Nerve - Tibial Male 50-59 Up AATK ABCA10 ABCA8 ADAMTS14 AFAP1L2 AHR ANGPTL7 APOD ARHGAP19 ARHGAP39 ARHGEF10 BIRC7 BMP8B CDH19 CHL1 CLDN19 CNTF COL28A1 CYB5R2 DCLK3 DHH DRP2 EBF2 EGFL8 EHBP1 EMILIN3 ENTPD2 EPB41L2 FGFBP2 FIGN FOXD1 FOXD2 FOXD3 GAS2L3 GFRA3 GJC3 GLI1 GNRH1 GRIK3 HSPA12A IL17B IL34 INF2 INSC ITGA6 ITGB4 ITGB8 KANK4 KCNK12 KIF19 LCTL LGI4 MEOX2 MIA MICALL2 MPZ NCMAP NEK1 NGFR OR6B2 OR6B3 PAPLN PDGFRL PLEKHA4 PLXNB3 PMP22 PODNL1 PRICKLE1 PRIMA1 PRRG3 PRX PTCH1 PTGFR PTPDC1 RHBDF1 SBSPON SCN7A SECISBP2L SEMA3B SEMA4C SFRP5 SHC4 SHH SLC25A48 SLC2A1 SMCO3 SORCS1 SORCS2 SPTBN5 ST6GALNAC2 STARD13 SYT10 THSD7A TLDC2 TMPRSS5 USP53 VIT VWA1 WNT6 XKR4 Skin - Sun Exposed (Lower Leg) Male 60-69 Up AADACL2 ABCA12 ACER1 ADGRF2 ADGRF4 ALOX12B ALOXE3 ANKRD35 BICD2 BPIFC C1ORF68 C2CD4D CA6 CALML5 CASP14 CDHR1 CDSN CENPP CLEC2A COL17A1 CTNNBIP1 CWH43 CXCL14 CYP4F22 DAPL1 DCT DEGS1 DLX3 DLX5 DMKN DSC1 DSC3 DSG1 DSP EFNA3 EPHB3 EPPK1 EXPH5 FAM110A FAM83B FAM83C FAM83G FLG FOXN1 GJB4 HS3ST6 IDE IFFO2 IGFL2 IGFL3 IL36B IL36RN JUP KCNK7 KLC3 KLK5 KLK7 KLRF2 KPRP KRT1 KRT10 KRT14 KRT2 KRT80 LGALS7B LGALSL LIPM MLANA NIPAL4 PARD6G PERP PKP1 PLA2G4E PNPLA1 POF1B POU2F3 POU3F1 PSAPL1 RASSF10 RDH12 SAPCD1 SDR9C7 SERPINA12 SERPINB5 SERPINB7 SLC52A1 SRY TFAP2A TFAP2C THEM5 TINCR TMEM45A TMPRSS13 TNFRSF19 TUFT1 TYR TYRP1 UNC93A WNT3 ZNF750 Adipose - Subcutaneous Male 60-69 Up ACKR1 ACKR3 ADAMTS5 ADCY4 ADGRL4 ADRA2A AGTR1 ANGPT4 ANGPTL2 ANGPTL5 APOL3 APOLD1 ARHGAP20 ARHGAP29 ARHGEF15 ATP8B4 AVPR2 CD34 CD36 CFD CILP CLDN5 CLEC14A CLEC3B CPXM1 CYGB EBF1 EBF3 ECSCR EDN1 FAM124B FGD5 FGF16 GFRAL GGT5 GPC3 HTR1F INHBB ITIH5 KCTD12 KRTAP13-4 LHX6 LRRC32 LRRC8C LVRN MEOX1 MEOX2 MFAP5 MMRN2 MYCT1 NEDD9 PECAM1 PLIN1 PLIN4 PRRX1 REM1 S1PR1 SASH1 SEMA3G SLIT3 SNRK SPRY1 STEAP4 SYNE3 TACR1 TIMP3 TNMD UVRAG WNT11 Muscle - Skeletal Male 60-69 Up ACTA1 ACTN2 ALDOA AMPD1 ANKRD23 ANKRD39 APOBEC2 ART1 ASB10 ASB16 ATP1B4 ATP2A1 BIN1 C10ORF71 CA3 CACNA1S CACNG1 CACNG6 CAP2 CAPN3 CASQ1 CAV3 CHRNA10 CKM CLCN1 CMYA5 CUTC DCAF6 DUSP13 EEF1A2 ENO3 FBP2 FXR1 GAMT IDI2 JPH1 JSRP1 KBTBD12 KCNA7 KLHL33 KLHL41 LINGO4 LMOD3 LRRC20 LRRC38 MACROD1 MAPK12 MSS51 MYBPC1 MYBPC2 MYH2 MYL1 MYLK2 MYOT MYOZ1 MYOZ3 MYPN NEB NRAP PACSIN3 PDE4DIP PDLIM3 PFKM PGM1 PGPEP1L PHKG1 POPDC3 PRKCQ PTGES3L PYGM RAPSN RBM24 RNF123 RPL3L RYR1 SEMA6C SH3BGR SLN SMTNL1 SMTNL2 SRPK3 STAC3 SYPL2 TCEA3 TMEM38A TMOD4 TNNC2 TNNI1 TNNI2 TNNT1 TNNT3 TPM3 TRDN TRIM72 TTN TXLNB USP13 VGLL2 YBX3 YIPF7 Artery - Tibial Male 60-69 Up ACAN ACTA2 ACTN4 ADARB1 ADIRF AEBP1 ALDH1B1 AMIGO2 ARHGEF17 ARHGEF39 BCAM C11ORF96 C12ORF75 CCDC3 CHSY3 CLIC4 CNTN4 COL14A1 COL18A1 COL8A2 COMP CPED1 CRIP1 CRLF1 CRTAC1 CSPG4 CSRP2 DACT3 DSTN EDIL3 EFHD1 ENAH FBLIM1 FHL5 FMOD FOXC1 FOXC2 FOXL1 FRY GPC6 HAUS7 HEY2 HTR1B ID2 IGFBP7 IGFBPL1 ITGA5 JAG1 JAK2 KCNAB1 KCTD10 LPP MAP3K7CL MBNL1 MCAM MSRB3 MUSTN1 MYO1D NDUFA4L2 NOTCH3 NTF3 NTRK3 P2RX1 PGF PLS3 PMEPA1 PPP1R14A PRELP PRKG1 PRSS23 RASL12 RASSF3 RCAN2 RERGL RHOB RNF180 ROCK1 RRAS RSU1 SDK1 SFRP2 SH3BGRL SMAD7 SMIM10 SORBS2 SOST SPEG STK38L SUSD5 SYTL2 TAGLN TASP1 TBX18 TBXA2R TMEM181 TMEM47 TRABD2B WFDC1 WTIP ZFHX3 Nerve - Tibial Male 60-69 Up AATK ABCA10 ABCA8 ADD3 AFAP1L2 AHR ANGPTL7 APOD ARHGAP19 ARHGAP39 ARHGEF10 BIRC7 BMP8B C2ORF88 CDH19 CHL1 CLDN19 COL28A1 CYB5R2 CYP2U1 DCLK3 DHH DISC1 DRP2 EBF2 EGFL8 EHBP1 EMILIN3 ENTPD2 EPB41L2 FIGN FOXD1 FOXD2 FOXD3 GAB1 GAS2L3 GFRA3 GJC3 GLI1 GNRH1 GRIK3 HSPA12A IL17B IL1RAPL1 IL34 INF2 INSC ITGA6 ITGB4 ITGB8 KANK4 KIF19 LCTL LGI4 MIA MICALL2 MPZ NCMAP NEK1 NGFR NRBP2 OR6B2 PAPLN PLAG1 PLEKHA4 PMP22 PRICKLE1 PRIMA1 PRRG3 PRX PTCH1 PTPDC1 RHBDF1 SBSPON SCN7A SECISBP2L SEMA3B SEMA4C SFRP5 SH3PXD2A SHC4 SHH SLC25A48 SLC2A1 SLITRK5 SMCO3 SORCS1 SPTBN5 ST6GALNAC2 STARD13 SYT10 TET1 THSD7A TLDC2 TMPRSS5 USP53 VIT VWA1 WNT6 XKR4 Heart - Atrial Appendage Male 60-69 Up ACTC1 ADAMTS7 ADAMTSL2 ALPK2 ANKRD1 ASPG BAMBI BMP10 C14ORF180 C17ORF107 CASQ2 CCDC141 CHRNE CIB2 COLQ CORIN CPNE5 CPT1B CRIP2 CYP2J2 CYSLTR2 DAND5 DHRS7C DKK3 DOK7 EIF1AY EIF1B ENG FABP3 FAM78A FBLN2 FBXO40 FGF12 GATA4 GRXCR2 HCN4 HHATL HRC HSPB2 HSPB3 HTRA3 IGSF5 ITGB1BP2 KRBA1 LAPTM4B METTL7B MYBPC3 MYBPHL MYH6 MYH7B MYL4 MYL7 MYLK3 MYOZ2 MYZAP NDUFA11 NDUFAB1 NEBL NES NKX2-5 NMRK2 NPPA NPPB NRTN OR10P1 OTOGL PABPC4L PAM PCOLCE2 PLA2G5 POPDC2 PRKAG2 PRR32 PXDNL RABGAP1L RBM20 RBPMS2 RD3L RILPL1 RNF207 S100A1 SBK2 SBK3 SCN5A SHD SLC25A4 SLC4A3 SMPX SSTR5 TBX20 TBX5 TECRL TMEM182 TNNI3K TNNT2 TRIM55 TSPAN18 UQCRB VASH1 WNK2 Heart - Left Ventricle Male 60-69 Up ACTC1 ASB18 ASIP BCO2 BSG C14ORF180 CASQ2 CCDC141 CDH2 CHCHD10 CKMT2 COQ10A COX5A COX5B COX6A2 COX7A1 COX7B CPT1B CRYAB CSDC2 CSRP3 DAND5 DECR1 EIF1AY EIF1B FABP3 FGF18 FHL2 FHOD3 FITM2 GJA3 HHATL HRC HSPB3 HSPB7 ITGB1BP2 KLHL31 LDB3 LRRC10 LSMEM2 MAPKAPK3 MDH1 MLYCD MPC1 MSRB2 MT1HL1 MTUS2 MYBPC3 MYH7 MYH7B MYL2 MYL3 MYLK3 MYOM2 MYOZ2 MYZAP NDUFA1 NDUFA8 NDUFAB1 NDUFB1 NDUFB3 NDUFS6 NEBL NKX2-5 NMRK2 PDE1C PDHA1 PKP2 PLN POPDC2 PPM1K PXDNL RBM20 RD3L RNF207 RYR2 S100A1 SCN5A SDHA SGCG SLC25A30 SLC25A4 SLC41A1 SLC4A3 SLC8A1 SMCO1 SMPX SMYD2 TCF15 TECRL TENM2 TIMM8B TLL2 TNNI3 TNNI3K TNNT2 TPM1 UQCRB UQCRC1 UQCRQ Thyroid Male 60-69 Up AMELY ATP13A4 BMP8A C16ORF89 CLN5 COL23A1 CPQ CRABP1 CRYGN CYTH2 DAPK2 DIO1 DIO2 DUOX2 EPOR EXOC3L2 FGFRL1 FOXE1 FREM2 FSCN2 GAL3ST3 GLCCI1 GOLGA8B GOLGA8M GRK1 HHEX HIRA HOOK3 IFT140 INPP5J IQCA1 IVD IYD KATNAL2 KCNC3 KCNJ16 KLHL14 LCN12 LIPG LIPI LPCAT2 LRP2 LRRC75B MGAT4C MPPED2 MROH1 MSANTD2 MT1F MUC15 NKX2-1 OR2A1 OR2T8 PABPC1L PAX8 PBX4 PDE8B PKHD1L1 PLA2G6 PLA2R1 PLEKHG4B PLEKHH1 PLVAP PRTG RCBTB1 RECQL5 RGL3 RHPN1 RTN4RL2 S100A5 SALL1 SALL4 SCX SHISA2 SLC12A8 SLC16A11 SLC25A29 SLC26A4 SLC26A7 SLC4A11 SLC4A5 SLC5A3 SLC5A8 SNX1 SNX22 SUCNR1 TBL1Y TCERG1L TFF3 TG TLE6 TPMT TPO TSHR WDR72 WDR86 ZBED2 ZNF114 ZNF486 ZNF804B ZNF90 Lung Male 60-69 Up A2M ACVRL1 ADAMTS8 ADGRF5 ADGRL2 AGER ARAP3 ARSI BCL6B BMP5 BMPR2 C20ORF202 CALCRL CASS4 CCDC102B CD274 CDH5 CLEC1A COL6A5 COL6A6 COX4I2 DOCK4 DOCK6 EFCC1 EMP2 EPAS1 ESM1 FAM162B FCN3 FGFR4 FMO2 FOLR1 FUT1 GALNT18 GBP4 GGTLC1 GIMAP8 GPC3 GPRC5A GRK5 HECW2 HGF HIGD1B HTR3C HYAL2 ICAM1 IL15RA IL1RL1 IL7R INMT KCNS3 LAMC3 LRRN4 LTK LUM MACF1 MS4A15 MSR1 NCKAP5 NDNF NKD2 OLR1 PAG1 PALD1 PCDH12 PCDH17 PECAM1 PHEX PIEZO2 PLEKHH2 PODXL PTGIR PTPRB RAMP3 RASIP1 RBMS2 RGCC RSPO4 RTKN2 SFTA2 SH2D3C SHROOM4 SLC6A4 SLCO2A1 SLIT2 STARD8 TAL1 TBX2 TBX4 TCF21 TEK TFEC TFPI TMEM100 TMEM74B TRPC6 VEGFD VIPR1 WNT2 WNT3A Spleen Male 60-69 Up ABI3 ANXA2R BANK1 BTN3A1 BTN3A2 BTN3A3 C1QA C1QB C1QC CABP4 CARD9 CCL14 CCL24 CCM2L CD163L1 CD19 CD1C CD1D CD200R1 CD4 CD5L CD72 CD79B CD8A CDCP2 CNR2 CPLX3 CSAG2 CSF1R CXCL13 CXCL6 CXCR5 DNASE1L3 EMID1 EPHA8 EXOC3L1 FAM9C FASLG FCRL1 FCRL2 FCRL3 FES FGD2 FHOD1 FLI1 GAB3 GDPD2 GDPD5 GPR182 GSDMD HLA-DOB HLA-F HMOX1 HYAL1 HYAL2 IL10RA ITGAD KAZALD1 LILRA4 LILRB1 LILRB5 LRTM1 MPEG1 MS4A7 MZB1 NLRC3 NOS3 NOX5 NPY1R NR5A1 OR2AJ1 OR5AK2 OR9G4 P2RX5 P2RY6 P3H2 PARP15 PATL2 PDE2A PDE6G PDLIM2 PITPNM3 PRR5 PRR5L PSTPIP2 RENBP S100Z SCN11A SIGLEC12 SLC9A5 SPIC STAB1 STAB2 TDGF1 TLX1 TMC8 TMEM26 TRAPPC3L TTC24 VCAM1 Testis Male 60-69 Up ADAD2 ANKRD7 ANTXRL ATP8B3 AURKC AXDND1 BRDT BTG4 C11ORF65 C12ORF42 C5ORF58 C9ORF43 CATSPERD CATSPERG CCDC150 CCDC158 CCDC168 CCDC38 CCDC70 CCHCR1 CCT8L2 CFAP53 CFAP99 CHRNB4 CNBD2 COX6B2 COX8C CYLC2 DDX4 DDX53 DEUP1 DNAJC5G DYDC1 EFCAB3 EID3 ERVW-1 EXD1 FAM209A FAM209B FAM217A FAM228A FKBP6 FOXN4 GDPD4 GOLGA6A HSF2BP INSL6 IQCA1L IQCF1 KCNV2 KCTD19 KRBOX1 KRTAP20-4 LIN28A LIN28B LRRC36 LRRIQ3 MAJIN MOV10L1 NAA11 NACA2 NOXRED1 OR1R1P OR8G3P OTOA PDCL2 PHF7 PMFBP1 POTEA POTEC PRAMEF11 RDM1 RGPD3 RGPD4 RIBC2 SHCBP1L SIGLECL1 SLC9C2 SLCO6A1 SMIM2 SPATA31A1 SPATA31C1 SPATA31C2 SPATA31D1 SPATA31D3 SPINK2 STK31 TAS1R1 TMCO5A TPTE2 TSGA10IP USP29 VRTN WDR87 YBX2 ZAR1L ZIM3 ZNF541 ZNF705A ZPBP2 Prostate Male 60-69 Up ABCC4 ADGRA2 ALDH1A3 AMD1 ANO7 AR ARHGEF38 BMP5 C8ORF82 CDH26 CFAP69 CGNL1 CHD3 CHRNA2 COL16A1 CPA6 CPAMD8 CPLX3 CPNE4 CREB3L4 EBF4 EPHA3 EVX1 EYA1 FOLH1 FOXA1 GATA2 GCNT2 GLB1L2 GLB1L3 GLIS1 HOXA13 HOXB13 HOXD10 HOXD13 HOXD9 ISL1 KLK2 KLK3 KLK4 LMAN1L MESP1 MKX MLPH MSMB NBL1 NCAPD3 NEFH NKX3-1 NR2E3 NTF4 OR51E2 P2RX2 PAGE4 PAK1IP1 PDE11A POTEG POTEH POTEM PRAC1 PRAC2 PRDM8 RDH11 RFPL2 RIPPLY3 RLN1 RPS4Y2 SCUBE2 SHROOM1 SLC15A2 SLC30A4 SLC45A3 SMO SORD SP8 SPDEF SRD5A2 STEAP2 STRA6 TGFB3 TMCO4 TMPRSS2 TNFSF15 TRPC4 TRPM8 TRPV6 TTC6 TULP1 UPK3A WFDC1 WNT2 XKR5 ZNF350 ZNF613 ZNF615 ZNF761 ZNF813 ZNF816 ZNF827 ZNF888 Skin - Not Sun Exposed (Suprapubic) Male 60-69 Up AADACL2 ADGRF2 ADGRF4 ANKRD35 ANXA8L1 ARHGEF19 BICD2 BPIFC CAPNS2 CARD18 CCL27 CD207 CDHR1 CDX4 CENPP CLDN1 CLEC2A COL17A1 COL7A1 CST6 CXADR DEGS1 DLX3 DMKN DSC3 DSP EFNA3 ETV3 EXPH5 FAM83B FOXN1 GAL3ST4 GATA3 GJB3 GJB4 HLA-DQB2 HR HS3ST6 IGFL2 IGFL3 IL20RA IL20RB IRF6 IRX3 IRX4 KCNK7 KLC3 KLF4 KLRF2 KREMEN2 KRT1 KRT10 KRT14 KRT77 KRT80 KRTDAP LAMB4 LGALS7B LGALSL LIPK LYPD6B MFSD2A NECTIN4 NIPAL4 NKPD1 NR1D1 NXPH4 PARD6G PERP PGLYRP4 PLA2G4F PNPLA1 POU2F3 PPP1R13L RAB7B RDH12 RNF39 RORA SLC39A2 SPTSSB TFAP2A TFAP2C THEM5 TINCR TMEM254 TMEM45A TNFRSF18 TNFRSF19 TP63 TUFT1 VANGL2 VAV3 WEE1 WFDC5 WNT16 WNT3 WNT4 WNT7B ZNF273 ZNF750 Minor Salivary Gland Male 60-69 Up AGFG2 AGR2 ALDH1A3 ANKRD36C APCDD1L AQP5 ASCL3 ATP6V1B1 AZGP1 B3GNT6 BPIFB2 BPIFB6 C6ORF58 CCDC160 CCL28 CEP41 CHST9 CLDN24 CNMD CRACR2A CRACR2B CREB3L1 CRISP3 CYB561 DEFB1 DMBT1 EHF ELF5 ETV6 FAM177B FAM3D FBN3 FDCSP FOLR1 FUT2 GALNT4 GALNT6 GJC3 GLYATL2 GOLM1 GPRC6A HTN1 IRX1 KCNN4 KRT3 KRT7 LCN2 LHX8 LPO LRRC26 LTF LYZ MMP7 MUC19 MUC5B MUC7 MYCN NAALADL2 NKX2-6 NXPE2 ODAM OPRPN OTX1 PAX3 PHLDA1 PIGR PIP PLEKHS1 PLPP2 PROM1 PRR27 PRR4 RAD51B RNASE8 RNF183 SCGB3A1 SH3BP4 SLC6A14 SLITRK6 SLPI SMR3A SMR3B SOX9 SPDEF SPINK14 STATH SVOPL TCN1 TFCP2L1 TFF3 TMED3 TMEM63A TNFRSF11A TNFSF15 TOX3 TRPV4 VGLL1 WFDC2 XBP1 ZG16B Brain - Cortex Male 60-69 Up ABHD8 ADGRA1 ADGRB1 ADGRB2 ANKRD24 APC2 ATCAY BHLHA9 BRINP2 BRSK1 C2CD4C CABP1 CACNG7 CAMK1G CAMK2A CASKIN1 CBLN2 CCK CHD5 CHRM1 CIT CLEC2L COL26A1 CSMD1 CTNNA2 CUX2 DAGLA DBNDD1 DOC2A DPF1 EIF4E1B ELFN2 FAM163B FBXO41 FSD1 FXYD7 GABBR2 GALNT8 GRIN1 HAPLN4 HECW1 HSD11B1L ITPKA KCNAB2 KCNH3 KCNH5 KCNIP3 KCNJ4 KCNS1 KIF1A KIF5A LCN15 LHX2 LINGO1 LRFN2 LYNX1 MAP1A MAST3 MCF2L2 MCHR2 MGAT5B MPPED1 NAGPA NANOS3 NCALD NPM2 NRGN OLFM1 OPRD1 PACSIN1 PDXP PHF24 PI4KA PLEKHM2 PNMA3 PNMA6A PRKAR1B PTPRT R3HDM1 RAPGEF4 RHBDL3 RIMS3 RLBP1 RNF208 RPH3A RTP1 SHC3 SLC6A17 SNCB SNPH SNX32 SOHLH1 SPRN STX1A SYN1 TBR1 TESPA1 UNC5A VSTM2L ZDHHC22 Brain - Cerebellum Male 60-69 Up ABCG4 ACAP3 ADAM11 ALS2 ARHGEF33 BARHL1 BARHL2 BRICD5 CACNA1A CACNA1G CAMKK2 CARMIL3 CBLN1 CCDC175 CDH15 CDH22 CELSR3 CKMT1B CNPY1 DAB2IP DISP2 EN2 FAM131C FAT2 FGF17 FGF3 GABRD GALNT9 GNG13 GOLGA7B GRID2IP GRIN2C GRM4 IGLON5 KCNAB3 KCNC1 KCNK9 LCN8 LHX1 MAST1 MCF2L MDGA1 MEGF11 MMP24 MTCL1 MYT1 NBPF20 NEUROD2 NRXN2 OTX2 PAX6 PKD1 PLEKHD1 PLK5 PPFIA4 PRR35 PRRT2 PRSS51 PTH2 PVALB RAB26 RAB37 RBFOX3 RGS11 RNF112 SBK1 SCRT2 SHF SHISA8 SKOR1 SLC1A6 SLC22A31 SLC35F4 SLC6A7 SOGA1 SRGAP2 SRRM3 SRRM4 ST8SIA5 STRC TFAP2E TLE2 TLX3 TMC2 TMEM132E TMEM145 TMEM178A TMEM266 TNFRSF25 TRIM67 TRIM9 UNCX VSX1 WSCD2 XKR7 ZFYVE28 ZIC2 ZIC3 ZIC5 ZNF382 Cells - Cultured Fibroblasts Male 60-69 Up ADAM12 ADAM9 ADAMTS6 ADAMTSL1 ALDH1L2 ANXA2 ARSJ CALU CCBE1 CCDC80 CD109 CKAP4 CLEC11A COL12A1 COL1A1 COL1A2 COL5A2 COL6A3 CTHRC1 CUL4B DCBLD2 DKK1 DSEL DUSP10 EIF2AK4 FAP FBN1 FBN2 FGF5 FKBP10 FKBP14 FN1 FRMD6 GALNT5 GANAB GCNT1 GNPNAT1 GPR176 GPX8 GREM1 HAS2 HIF1A HMGA1 HMGA2 HOXC8 HS3ST3A1 HS3ST3B1 IGF2BP2 IGF2BP3 IKBIP ITGBL1 KCNK2 KDELR3 LGALS1 LMAN1 LOX LOXL2 MME MRC2 MYOF NECTIN3 NID2 NT5E OPN3 OR1J4 OSTC PAPPA PCDHGA11 PCDHGB4 PCOLCE PLOD1 PLOD2 PRR16 PTX3 RAI14 RCN1 RCN3 RECK RFX8 RRAS2 SEC22B SERPINE1 SPOCD1 SSR3 STEAP1 STEAP1B STT3A TGFBI TNFRSF10D TNPO1 TRAM1 TRAM2 TRNP1 TWIST1 TWIST2 TXNRD1 ULBP3 VGLL3 WNT5A YIPF5 Colon - Transverse Male 60-69 Up ACTG2 ADAMDEC1 CCL11 CDX1 CDX2 DPT ETHE1 FOXF1 GALR2 GLP2R GREM2 HAND1 HAND2 HOXA6 HOXB5 HOXB9 HTR3E JCHAIN LGALS4 MAB21L2 NKX2-3 NKX3-2 NOX1 NPY4R NTSR1 NXPE1 PDE9A PHOX2B PTGDR2 RXFP4 SH2D6 TRPM5 TSPAN11 UGT1A8 URAD VIP ZACN Whole Blood Male 60-69 Up ADGRG3 ADIPOR1 AKNA AOAH ARHGAP45 ARRB2 C5AR1 CAMP CARD19 CCL4 CCL5 CD247 CD300A CD300E CD300LB CD3E CD5 CD6 CD7 CD96 CEACAM3 CTSW CXCR4 CYTIP DHX34 DOK2 EPB42 FBXO7 FCAR FCN1 FCRL6 FKBP8 FMNL1 GATA1 GNLY GTPBP1 GYPC GZMA GZMB GZMH GZMM HBA1 HBA2 HBB HBD HBM HBQ1 HCAR2 HCAR3 HCST IL2RG ITGAL KIR2DL1 KIR2DL3 KIR2DS4 KIR3DL1 KIR3DL2 KLRB1 LCP2 LIM2 LSP1 MEFV MFSD2B MPP1 MXD1 NCR1 NCR3 NFKBID NINJ1 NKG7 NLRP3 OSM PADI4 PGLYRP1 PLAUR PRAM1 PRF1 PRSS57 PSTPIP1 PYHIN1 R3HDM4 RAC2 RELT SH2D2A SIPA1 SLA2 SLC25A37 SLC25A39 SLC2A3 SLC4A1 STK10 SYTL3 TAGAP TBX21 TGFB1 TNFRSF1B TREM1 TSPAN32 WAS ZAP70 Adrenal Gland Male 60-69 Up AADAC ABCB1 ABCC3 ABCF3 ADGRV1 AKAP7 AKR1B1 ALAD ALAS1 ALKAL2 AMHR2 AS3MT ASB4 C2CD2 C4B CELA1 CLRN1 CREBL2 CTNNAL1 CYB561A3 CYB5B CYP11A1 CYP11B1 CYP11B2 CYP17A1 CYP21A2 DEXI DHCR24 DLK1 DUSP16 EPHX1 ERN1 FAM166B FAM43B FDX1 FDXR FNDC4 GALM GNPTG GRAMD1B GRPEL1 GSTA1 GSTA3 GSTA4 HDHD3 HOXA5 HSD3B2 HSPD1 HSPE1 IDH1 IFITM10 KCNJ5 KCNK3 KCNN2 KCNQ1 KLHDC8B KLHL4 LONP1 MAP3K15 MAP3K5 MC2R MCOLN3 MGARP MRAP NR0B1 NR5A1 NXPH1 PAPSS2 PEBP1 PEX3 PLBD2 POR PORCN PPIF QPRT RARRES2 RBBP7 RBKS RDX RGN RMDN2 SCAP SCARB1 SEMA6A SLC16A9 SLC23A2 SLC47A1 SLC8B1 SNTB1 SOAT1 SREBF1 STAR TBC1D8B TBX3 TKFC TM7SF2 WHRN ZNF275 ZNF280A ZNF836 Artery - Aorta Male 60-69 Up ADRA1B ADRA2C AEBP1 ANO1 ANTXR1 ASPN BGN C1QTNF8 C5ORF46 C8ORF34 CD151 CDH13 CHSY3 CLEC18A COL21A1 COL8A1 COL8A2 CPXM2 CRISPLD1 CYTL1 EFEMP1 ELN EXT1 FAM180A FBLIM1 FBLN5 FMO2 FMOD FOXC1 FOXC2 FOXL1 FOXS1 FRZB GAS6 GDF7 GEM GLIPR1 HAPLN1 HAPLN3 HAUS7 HMCN1 IGFBP2 IGFBP7 ITGA10 ITGA11 ITGA8 ITGB5 ITGBL1 KALRN KCNK15 KCNK17 LDOC1 LIMS3 LIMS4 LOXL1 LTBP1 LTBP2 LTBP3 MEGF6 MFGE8 MGP MRAP2 MYH10 MYH9 MYO1D NAV1 NAV2 NOX4 NPR1 NXPH3 OGN OMD PCDH7 PDGFA PDGFD PID1 PKD2 PLS3 PRDM6 PRELP PRKG1 PTGIR PTGIS PXDC1 SMOC2 SOST ST6GAL2 STAC STK38L SUGCT SULF1 SUSD5 TBXA2R THBS2 TMEM47 TNFRSF11B TPH1 VCAN WWP2 ZNF385D Esophagus - Gastroesophageal Junction Male 60-69 Up ANKS1A ANTXR2 BARX1 C1QTNF3 CACNB2 CHRM3 COL4A5 COL4A6 CYSLTR1 DEFB124 DENND2A EML1 ERVFRD-1 FGL2 FOXF1 FOXF2 FOXP1 GRPR HOXA4 HOXB3 HOXB4 HPSE2 MAGEB17 MEIS1 MYH11 MYOC NKX6-1 NRP2 NTN1 P2RX2 PPP1R12C RGMB RSPO3 SCUBE1 SEMA3A SEMA3E SHISA3 SLC29A1 SMTN SYNM WLS Esophagus - Mucosa Male 60-69 Up A2ML1 ADH7 ALDH3A1 ANXA1 AQP3 BARX2 CALML3 CAPN1 CAPN14 CLIC3 CNFN CRABP2 CRCT1 CRNN CSTA CSTB CYSRT1 DSC2 DSG3 DYNAP ECM1 EDAR EMP1 ENDOU EPHA1 EPHA2 EPS8L1 EPS8L2 ESPL1 EVPLL FABP5 FAM83A FAM83H FGFBP1 FUT3 FUT6 FZD10 GBP6 GIPC1 GJB2 GNA15 GPR78 GRHL3 GRPEL2 GSTP1 HES2 IL1RN KLK10 KRT13 KRT4 KRT78 LAD1 LY6D LYPD2 MAL MALL MPZL2 MUC21 NMU OTOP3 PADI1 PAX9 PITX1 PPL PRSS27 PTK6 RAB25 RAET1E RAET1G RAET1L RHCG RHOD RHOV RIPK4 RNF222 RNF223 S100A14 S100A16 S100A2 SERPINB13 SFN SIM2 SMAGP SOX15 SPRR3 TBX6 TGM1 TGM3 TMEM184A TMEM40 TMPRSS11B TMPRSS4 TTC22 TTC9 TTLL12 TXN TXNDC17 UGT1A7 VSIG10L ZNF185 Esophagus - Muscularis Male 60-69 Up ACTG2 ADRB3 ANKS1A ARMC9 ARSB BCHE C1QTNF3 CACNA1H CACNB2 CCDC69 COL4A5 COL4A6 CYSLTR1 DENND2A DES DGKG DHX35 DPYSL3 EPHA7 ERVFRD-1 FBXO30 FGL2 FOXF2 FOXP1 GIPC3 HLF HOXA4 HPSE2 JPH2 KCNMB1 KCNQ4 KIAA0753 LHCGR LSM11 MYH11 MYL9 MYLK NKX6-1 NRP2 NTN1 P2RX2 PALLD PGM5 PLEKHO1 PPP1R12C PYGB RBPMS RGMA RGMB RGS2 S1PR3 SEMA3A SHISA3 SLITRK3 SMTN SYNM TPBG TRPC6 WLS WNT5B Stomach Male 60-69 Up A4GNT ADA ADAM28 AKR7A3 AKR7L ALDH1A1 ANKRD22 ANXA10 ASAH2 ATP4A ATP4B B4GALNT3 BAIAP2L1 BARX1 C9ORF152 CA2 CA9 CAPN13 CAPN8 CAPN9 CCKAR CCKBR CHIA CLDN18 CLIC6 COL2A1 CTSE CXCL17 CYP2S1 CYSTM1 DAZ1 DAZ4 DUSP19 EPN3 ERO1B ESRRB ESRRG FAM177B FAM3B FER1L6 FMO5 FOXA2 FOXA3 FRMD1 GBGT1 GCNT4 GHRL GKN1 GKN2 GPER1 GPR155 GPRC5C GRP KCNE2 KCNQ1 LGALS9C LIPF LIPH MCIDAS MECOM MFSD4A MUC1 MUC5AC MUC6 MYH13 MYRF NBPF12 PALM3 PDILT PGA3 PGA4 PGA5 PGC PIK3C2G PSCA PTGDR2 PXMP2 RASSF6 RFLNA RFX6 SLC26A9 SLC2A12 SLC4A2 SLC5A5 SLC9A2 SLC9A4 SULT1C2 TFF1 TFF2 TMED6 TMEM92 TOX3 TPCN2 TRIM50 TRIM73 TRIM74 VSIG1 VSIG2 VWA2 XYLT2 Pancreas Male 60-69 Up AKR7A3 AMY1A AMY1B AMY1C AMY2A AMY2B ANXA4 AQP12A AQP12B AQP8 ARL5C BHLHA15 BNIP3 CATSPERB CEL CELA2A CELA2B CELA3A CELA3B CFTR CHST4 CLDN10 CLPS CLPSL1 CLPSL2 CPA1 CPA2 CPB1 CTRB1 CTRB2 CTRC CTRL CUZD1 EPB41L4B ERICH5 ERO1B ERP27 FAM3B FBXW12 FKBP11 G6PC2 GATM GCG GLP1R GNMT GP2 GPHA2 GPR119 GPR150 GRPR GUCA1C HOMER2 IL22RA1 INS KCNK16 KIRREL2 KLK1 LHFPL5 MNX1 NR5A2 ONECUT1 OR10G4 OR4D5 OR6M1 P4HB PDCD4 PDIA2 PDX1 PGGHG PKHD1 PLA2G1B PNLIP PNLIPRP1 PNLIPRP2 PRDX4 PRSS1 PRSS2 PRSS3 PTF1A RBPJL REG1A REG1B RNF186 SCTR SEL1L SERPINI2 SLC30A2 SLC30A8 SLC38A5 SLC39A5 SLC43A1 SLC4A4 SPINK1 SYCN TECPR1 TMED6 TMEM97 TPST2 TRPV6 XBP1 Adipose - Visceral (Omentum) Male 60-69 Up AADACL4 ABLIM3 ACER2 ADAMTS9 ADGRL4 ALDH1A3 ALOX15 ANGPTL2 ANO2 ARHGEF15 BNC1 BTNL9 C7 CCRL2 CD209 CD300LG CD36 CLDN15 CPXM1 CYYR1 FABP4 FAM89A FGF10 GAS1 GFPT2 GNAT3 GNG11 GPR4 HAS1 HBEGF HLX IGF2 ITLN1 KDR LRRN4 LUM LXN LYVE1 MEST MMRN2 MSLN MUC16 MYCT1 NOCT NOTCH4 NR1H3 NRP1 PCSK5 PDPN PPARG PRG4 PROCR PROKR1 RARRES1 RBP7 ROBO3 ROBO4 SDE2 SERPINE3 SOX17 SPAAR SPRY1 SRPX2 ST6GALNAC3 TIE1 TM4SF1 TMEM88 TSHZ2 UPK1B UPK3B VEGFC VWF WNT11 WT1 Small Intestine - Terminal Ileum Male 60-69 Up ACE ACE2 ACSL5 ADAMDEC1 ADGRG7 ALPI AMN ANKS4B ANPEP ANXA13 AOC1 APOBEC1 B3GALT5 BAIAP2L2 BTNL3 BTNL8 C11ORF86 C17ORF78 CCL21 CCL25 CCR9 CDHR2 CDHR5 CEACAM18 CEACAM20 CHST5 CLDN15 CPO CTLA4 DEFA5 DEFA6 DGAT1 DHRS11 DMBT1 DPEP1 ENPEP EPS8L3 ERICH4 FABP2 FABP6 FAM177B FCRL2 GBA3 GIMD1 GIP GUCA2A HKDC1 HNF4G IL2 ITLN2 KCNJ13 MALRD1 MEP1A MEP1B MIA2 MOGAT3 MS4A10 MS4A8 MTTP MUC17 MUC2 MUC3A MYO1A MYO7B MYRFL NAALADL1 NLRP6 P2RY4 PLCB3 PRAP1 RBP2 REG4 RGS13 SI SLC10A2 SLC13A2 SLC15A1 SLC17A8 SLC23A1 SLC28A2 SLC39A4 SLC51B SLC52A1 SLC5A1 SLC5A9 SLC6A19 SLC7A9 SMIM24 SPINK4 SULT1A2 TAS2R38 TBX10 TM4SF20 TM6SF2 TMEM253 TMIGD1 TMPRSS15 TREH VIL1 XPNPEP2 Colon - Sigmoid Male 60-69 Up ACTG2 ADAM33 ARHGEF25 ATF4 ATP2B4 BAG2 BTC CACNA1C CACNA1H CCDC69 CCL11 CDK8 CHRM2 CNGA3 CNN1 COL6A1 CSRP1 DCP1B DES DPT EML1 FBXL22 FNDC1 FOXF1 FOXP2 GALR2 GDNF GJC1 GLP2R HAND1 HAND2 HMCN2 HOXB2 HOXB3 HOXB4 HOXD10 HOXD11 HOXD12 HOXD13 HOXD9 ILK KCNH2 KCNQ4 KIZ KLHL23 LIMS2 LRRC3 MAB21L2 MASP1 MDM1 MEIS1 MID1 MRGPRF MYH11 MYL6 MYL9 MYLK NKX2-3 NKX3-2 NME4 NPY4R NRP2 NT5DC3 NTSR1 NXN OLFML2A PBX3 PDE9A PDLIM4 PDLIM7 PHOX2B PLA2G2C PLEKHO1 PLXNB3 PNCK PPP1R12C PTGFRN PTGS1 RGS10 RNF150 ROR2 SEMA3A SLC5A7 SMTN SPOP SSC5D STON1-GTF2A1L SUPT20HL1 SYNM TACR2 TBC1D1 TEAD3 TES TGFB1I1 TNFAIP8L1 TSPAN11 TSPAN2 WFDC1 ZACN ZNF219 Breast - Mammary Tissue Male 60-69 Up ACKR1 ADAMTS3 ADCY4 ADGRL4 ANGPT4 ANKRD30A ARHGAP29 ARHGAP40 ARHGEF15 AVPR2 BTNL9 CD300LG CD36 CDH5 CLDN5 CST9 CYYR1 DHRS2 DLL4 ECSCR EGFL7 ELOVL5 EMCN FABP4 FAM124B FGF10 GLRA3 GNG11 GPIHBP1 GPR146 GSC HCAR1 HSPA12B INHBB INPP4B IRX5 KIF12 KLHDC7A MEOX1 MMRN2 MYB MYCT1 NLRP13 NLRP8 NOSTRIN NOTCH4 NPY2R PAPPA2 PI15 RAB6C RAPGEF3 RBP7 ROBO4 S1PR1 SCGB2A2 SEC14L2 SELP SEMA3G SGK3 SOCS2 SPAAR ST8SIA6 STC2 TACR1 TBC1D9 TFAP2B TMEM26 TNN TRPS1 TTC6 USHBP1 VTCN1 XBP1 ZNF689 Cells - EBV-transformed Lymphocytes Female 60-69 Up AICDA APOBEC3G ATAD5 AURKB BATF BFSP2 BLNK BORA BRCA2 BTLA CD226 CD27 CD48 CD70 CD79A CD80 CENPM CLEC17A CLEC2D CXCR3 DEPDC1B DNA2 E2F7 EAF2 EDEM1 EED ESCO2 FAM111B FAM72A FAM72B FAM72C FAM72D FCRL5 FCRLA FEN1 GNGT2 GPR15 HELLS IFIH1 IKZF3 IL21R IL23R IRF4 IRF5 ITGA4 ITGB7 LAX1 LGALS14 LPXN LTA LY75 MAP4K1 MCM2 MCOLN2 MS4A1 MX1 MYBL2 NUP210 NUSAP1 OAS2 OR2B6 ORC1 P2RY10 PAX5 PCLAF PCNA PIF1 PIK3R6 PLCG2 PMAIP1 PNOC POLQ POU2AF1 POU2F2 PUDP RAD54B RASGRP3 RB1 RFC3 RRM2 SIT1 SLAMF1 SLAMF7 SP140 STAP1 STAT1 TCL1A TIFA TLR7 TMSB15B TNF TNFRSF13B TNFRSF17 TNFRSF8 TNFSF11 TNFSF9 TTF2 WDFY4 WNT10A ZC3H12D Whole Blood Female 60-69 Up ACAP1 ADAM8 ADGRE5 ADGRG3 ADIPOR1 ALAS2 AOAH APBB1IP APOBR ARHGAP45 ARRB2 BIN2 C1ORF162 C5AR1 CCL5 CD300A CD7 CDKN2D CEACAM21 CEACAM8 CSF3R CST7 CTSW CXCR1 CXCR4 CYTIP DHX34 EPB42 FBXO7 FCAR FCN1 FGD3 FKBP8 FMNL1 GATA1 GP9 GPSM3 GYPC GZMB HBA1 HBA2 HBB HBD HCST IFIT1B IFITM2 IL18RAP IL2RG ITGAM ITGAX ITGB2 KIR2DL1 KIR2DL4 LAPTM5 LCP1 LCP2 LILRB3 LRRC25 LSP1 MEFV MFSD2B MPP1 MXD1 MYO1F NCF2 NKG7 NLRP3 OR2W3 PADI4 PF4 PGLYRP1 PRAM1 PROK2 PTPRC R3HDM4 RAC2 RGL4 RHOG RIN3 SAMSN1 SELL SELPLG SIRPB1 SLC11A1 SLC25A37 SLC25A39 SLC2A3 SLC4A1 SMAP2 SPI1 SYTL3 THEMIS2 TLR2 TMEM71 TNFRSF1B TREM1 TRIM58 VSIR WAS XPO6 Cells - Cultured Fibroblasts Female 60-69 Up ADAM12 ADAM9 ADAMTS2 ALDH1L2 ANXA2 ANXA5 ARSJ CALR CALU CCBE1 CCDC80 CD109 CEMIP CKAP4 CLEC11A COL12A1 COL1A1 COL1A2 COL5A2 COL6A3 CTHRC1 CUL4B DKK1 DSEL DUSP10 EIF2AK4 FAP FBN1 FBN2 FKBP10 FKBP14 FN1 FRMD6 GALNT5 GANAB GCNT1 GPR176 GPX8 GREM1 HIF1A HOXC8 HS3ST3B1 IGF2BP2 IGF2BP3 IKBIP ITGBL1 KCNK2 KDELR3 KIF20A LGALS1 LMAN1 LOX LOXL2 MME MRC2 MYOF NECTIN3 NID2 NT5E OPN3 OSTC P3H1 P4HA2 PAPPA PCDH18 PCDHGA11 PCDHGA12 PCDHGB4 PCOLCE PDIA6 PLOD1 PLOD2 PRR16 PSG5 PTX3 PXDN RCN1 RCN3 RECK SEC22B SERPINE1 SERPINH1 SLC2A10 STC2 STEAP1 STEAP1B STT3A TGFBI THBS1 TMEM119 TNFRSF10D TRAM1 TRAM2 TWIST1 TWIST2 TXNRD1 ULBP3 VGLL3 WNT5A YIPF5 Lung Female 60-69 Up A2M ABCA3 ACVRL1 ADAMTS8 ADGRF5 ADGRL2 AGER ANOS1 ATP11A C20ORF202 CACNA2D2 CALCRL CASS4 CCDC102B CCL23 CEACAM6 CLIC2 COL6A5 COL6A6 COX4I2 CROCC2 CTSH DOCK4 DRAM1 EMP2 EPAS1 FCN3 FGFR4 FOLR1 GALNT18 GGTLC1 GPC3 GPRC5A HECW2 HYAL2 ICAM1 IL15RA IL1RL1 IL7R INMT LAMC3 LAMP3 LPCAT1 LTK MS4A15 MSR1 NAPSA NCKAP5 NDNF NKD2 OLR1 PAG1 PAPSS2 PCDH17 PHEX PLA1A PLEKHH2 PODXL PTGIR PTPRB RAMP3 RBMS2 RGCC ROS1 RP1 RS1 RSPO4 RTKN2 SCGB1A1 SCGB3A2 SFTA2 SFTPA1 SFTPA2 SFTPB SFTPC SFTPD SHROOM4 SLC34A2 SLC39A8 SLC6A4 SLCO2A1 SLCO4A1 SLIT2 SMAD6 STARD8 SUSD2 TAL1 TBX2 TBX4 TCF21 TEK TFEC TFPI TMEM100 TNIP3 UNC13B VEGFD VIPR1 WNT2 WNT3A Thyroid Female 60-69 Up ADM2 AFAP1L2 ATP13A4 BMP8A C16ORF89 CLN5 COL23A1 COL4A3 CRABP1 CRYGN CYTH2 DAPK2 DIO1 DMRT3 EPOR EXOC3L2 FGFRL1 FOXE1 FRAS1 FSCN2 GAL3ST3 GLCCI1 GOLGA8B GOLGA8M GRK1 HHEX HIRA HOOK3 IFT140 IL15 INPP5J IQCA1 ISM1 IVD IYD KATNAL2 KCNC3 KCNJ16 KLHL14 LCN12 LIPG LRP2 LRP8 LRRC75B MPPED2 MROH1 MSANTD2 MT1F MUC15 NKX2-1 NPNT NUPR1 OR2A1 OR2A42 PABPC1L PAN2 PARM1 PAX8 PBX4 PDE8B PKHD1L1 PLA2G6 PLA2R1 PLEKHH1 PLVAP PRKX PRTG RCBTB1 RECQL5 RGL3 RHPN1 S100A5 SALL1 SALL4 SCX SH3D21 SLC12A8 SLC16A11 SLC17A5 SLC25A29 SLC26A4 SLC26A7 SLC4A11 SLC5A8 SNX1 SNX22 SUCNR1 TCERG1L TG TLE6 TPMT TPO TSHR WDR72 WDR86 ZBED2 ZNF114 ZNF486 ZNF804B ZNF90 Adrenal Gland Female 60-69 Up AADAC ABCB1 ABCC3 ABCF3 AKAP7 AKR1B1 ALAD ALAS1 ALKAL2 AMHR2 AQP11 AS3MT ASB4 C2CD2 CELA1 CHRNA3 CLRN1 CREBL2 CYB561A3 CYB5B CYP11A1 CYP11B1 CYP17A1 CYP21A2 DBH DDB1 DEXI DHCR24 DLK1 DUSP16 EPHX1 ERN1 FAM166B FDX1 FDXR GALM GSTA1 GSTA3 GSTA4 HDHD3 HOXA5 HSD3B2 HSPD1 HSPE1 IFITM10 KCNJ5 KCNK3 KCNN2 KCNQ1 KLHDC8B KLHL4 LONP1 MAP3K15 MAP3K5 MC2R MCOLN3 MGARP MRAP MYO7A NR0B1 NR5A1 NXPH1 PAPSS2 PEBP1 PEX3 PHOX2A PLBD2 PORCN PPIF RARRES2 RBBP7 RDX RGN RMDN2 SCAP SCARB1 SEMA6A SERPINA5 SLC16A9 SLC18A1 SLC23A2 SLC40A1 SLC47A1 SLC8B1 SNTB1 SOAT1 SREBF1 STAR TBC1D8B TBX3 TH TKFC TM7SF2 TRIM24 VWA5B2 WHRN ZNF275 ZNF280A ZNF836 ZSWIM5 Spleen Female 60-69 Up BANK1 BLK BTN3A1 BTN3A2 BTN3A3 C1QA C1QB C1QC CABP4 CCL14 CCL24 CCM2L CCR5 CD163L1 CD19 CD1C CD22 CD5L CD72 CD79B CD84 CD8A CDCP2 CERKL CNR2 CR2 CSF1R CXCL13 CXCR5 CXCR6 DNASE1L3 EXOC3L1 FAM9C FCMR FCRL1 FCRL2 FCRL3 FGD2 FHOD1 FLI1 GAB3 GDPD2 GDPD5 GPR171 GPR182 GRAP HLA-DOB HLA-F HYAL1 HYAL2 IL10RA IL24 IRF8 ITGAD KLRC4 KLRK1 LILRA4 LILRB5 LRTM1 MPEG1 MS4A1 MS4A7 NLRC3 NOS3 NOX5 NPY1R NR5A1 NTN4 OR2AJ1 OR5AK2 OR9G4 P2RX5 P2RY6 PARP15 PATL2 PITPNM3 PSTPIP2 RENBP SCML4 SCN11A SEMA3D SLC38A11 SLC9A5 SP140L SPIC STAB1 STAB2 TDGF1 TIGIT TLX1 TMC8 TMEM26 TNFRSF13C TRAPPC3L TTC24 TXK UBASH3A VCAM1 ZNF80 ZNF831 Pancreas Female 60-69 Up AMY1A AMY1B AMY1C AMY2A AMY2B AQP12A AQP12B AQP8 ARL5C BHLHA15 CATSPERB CEACAM16 CEL CELA2A CELA2B CELA3A CELA3B CFTR CHST4 CLDN10 CLPS CLPSL1 CLPSL2 CPA1 CPA2 CPB1 CTRB1 CTRB2 CTRC CTRL CUZD1 EGF EPB41L4B ERICH5 ERO1B ERP27 FAM3B FBXW12 FKBP11 G6PC2 GATM GCG GLP1R GNMT GP2 GPHA2 GPR119 GPR150 GUCA1C HOMER2 IL22RA1 INS KCNK16 KIRREL2 KLK1 LHFPL5 MNX1 NPHS1 NR5A2 ONECUT1 OR10G4 OR4D5 OR8D4 P4HB PDIA2 PDX1 PGGHG PKHD1 PLA2G1B PNLIP PNLIPRP1 PNLIPRP2 PRDX4 PRSS1 PRSS2 PRSS3 PTF1A RBPJL REG1A REG3G RNF186 RRBP1 SCTR SEL1L SERPINA4 SERPINI2 SLC16A12 SLC30A2 SLC30A8 SLC38A5 SLC39A5 SLC43A1 SLC4A4 SPINK1 SYCN TECPR1 TMED6 TMEM97 TPST2 XBP1 Heart - Left Ventricle Female 60-69 Up ACTC1 ANKRD1 ASB18 B3GALT2 BCO2 BSG BZW2 CASQ2 CCDC141 CDH2 CHCHD10 CKMT2 COQ10A COX5A COX6A2 COX7A1 COX7B CPT1B CRYAB CSDC2 CSRP3 DAND5 DDO DECR1 EIF1B FABP3 FGF18 FHL2 FHOD3 FITM2 GJA3 HACD1 HHATL HRC HSPB3 HSPB7 IGSF5 ITGB1BP2 KLHL31 LRRC10 LSMEM2 MAPKAPK3 MDH1 MFN2 MLYCD MPC1 MT1HL1 MTUS2 MYBPC3 MYH7 MYH7B MYL2 MYL3 MYLK3 MYOM2 MYOZ2 MYZAP NDUFA1 NDUFAB1 NDUFS6 NEBL NKX2-5 NMRK2 OGDH PDE1C PDHA1 PKP2 PLCXD3 PLN POPDC2 PPM1K RBM20 RD3L RYR2 S100A1 SCN5A SDHA SGCG SLC25A30 SLC25A4 SLC41A1 SLC4A3 SLC8A1 SMCO1 SMPX SMYD1 SMYD2 SRL SYNPO2L TCF15 TECRL TENM2 TMEM182 TNNI3 TNNI3K TNNT2 TPM1 UQCRC1 UQCRQ XPR1 Artery - Aorta Female 60-69 Up ADAMTSL3 ADRA1B AEBP1 ANO1 ANTXR1 ASPN BGN C1QTNF2 C1QTNF8 CA5B CDH13 CHSY3 CMKLR1 COL14A1 COL21A1 COL8A1 COL8A2 CPXM2 CRISPLD1 CYTL1 EFEMP1 ELN EXT1 FAM180A FBLIM1 FBLN5 FGL2 FMO2 FMOD FOXC2 FRZB GABRR1 GAS6 GDF7 HAPLN1 HAPLN3 HAUS7 HMCN1 IGFBP2 IGFBP7 ITGA10 ITGA11 ITGA8 ITGB5 ITGBL1 KALRN KCNA5 KCNK15 KCNK17 LDOC1 LGR6 LIMS4 LTBP1 LTBP2 LTBP3 MEGF6 MFGE8 MGP MRAP2 MYH10 MYH9 MYO1D NAV1 NAV2 NOX4 NPR1 NXPH3 OGN OMD PCDH10 PCDH7 PDGFA PDGFD PID1 PKD2 PLD5 PLS3 PRDM6 PRELP PRKG1 PROS1 PXDC1 SCARA3 SMAD7 SMOC2 SOD3 SOST ST6GAL2 STAC STK38L SUGCT SULF1 SUSD5 TBXA2R THBS2 TNFRSF11B TPH1 VCAN WWP2 ZNF385D Small Intestine - Terminal Ileum Female 60-69 Up ACE ACE2 ACSL5 ADGRG7 ALPI AMN ANKS4B ANPEP AOC1 APOA4 APOBEC1 ATOH1 BAIAP2L2 BTNL3 C11ORF86 C17ORF78 CAPN13 CDHR2 CDHR5 CEACAM18 CEACAM20 CES2 CHST5 CLCA1 CLDN15 CPO DEFA5 DEFA6 DGAT1 DPEP1 ENPEP ERICH4 FABP2 FABP6 FADS6 FAM151A GBA3 GUCA2A GUCY2C HKDC1 HNF4G ITLN2 KCNJ13 MALRD1 MEP1A MEP1B MIA2 MISP MOGAT3 MS4A10 MS4A8 MTTP MUC17 MUC2 MUC3A MYO1A MYO7B MYRFL NAALADL1 NLRP6 OAT P2RY4 PLCB3 PRAP1 RBP2 REG4 SI SLC10A2 SLC13A1 SLC13A2 SLC15A1 SLC17A8 SLC23A1 SLC28A2 SLC39A4 SLC3A1 SLC51B SLC52A1 SLC5A1 SLC5A9 SLC6A19 SLC7A9 SMIM24 SPINK4 SULT1A2 SULT1C3 TAS2R38 TBX10 TM4SF20 TM6SF2 TMEM150B TMEM236 TMEM253 TMIGD1 TREH TUBAL3 UGT1A5 UGT2A3 VIL1 XPNPEP2 Colon - Sigmoid Female 60-69 Up ACTG2 ADAM33 ANKFY1 ARHGEF25 ATP2B4 BAG2 BMP3 BTC CAB39L CACNA1C CACNA1H CDK8 CHRM2 CNN1 COL24A1 COL6A1 CSRP1 DCP1B DHX35 DPT EML1 FBXL22 FOXF1 FOXP2 FZD7 GALR2 GDNF GJC1 GLB1L2 GLP2R HAND1 HAND2 HDAC4 HLX HMCN2 HOXB3 HOXD10 HOXD11 HOXD12 HOXD13 ILK KCNMA1 KCNQ4 KIZ KLHL23 LIMS2 LRCH2 LRIG1 LRRC3 MAB21L2 MASP1 MDM1 METTL24 MID1 MRGPRF MYH11 MYL6 MYL9 MYLK NKX2-3 NKX3-2 NME4 NRP2 NT5DC3 NTSR1 NXN PBX3 PDE3B PDLIM7 PDZRN4 PGM5 PHOX2B PLA2G2C PLEKHO1 PLXNB3 PNCK PTBP2 PTCHD1 PTGFRN RAB23 RGS10 RNF150 ROR2 SEMA3A SLC5A7 SMTN SPOP SSC5D STON1 STON1-GTF2A1L SYNM TACR2 TBC1D1 TES TGFB1I1 TMTC2 TNFAIP8L1 TSPAN11 TSPAN2 ZACN Colon - Transverse Female 60-69 Up ADAMDEC1 CCL11 CCL8 CDX2 GALNT12 GALR2 GLP2R GPR35 GREM2 HAND1 HEPH HHLA2 HOXA13 HOXA6 HOXB5 ISX JCHAIN LYPD8 MAB21L2 MLN MUC12 NKX2-3 NKX3-2 NPY4R NTSR1 NXPE1 NXPE4 P2RY14 PDE9A PIGZ PLA2G2C PRR15 PTGDR2 SLC26A3 TMEM236 TRIM31 TSPAN1 URAD ZACN Esophagus - Muscularis Female 60-69 Up AARD ACTG2 ADRB3 ANKS1A ANTXR2 ARMC9 ARSB CACNA1H CACNB2 CALD1 CHRM3 CNTNAP3 CNTNAP3B COL4A5 COL4A6 CYSLTR1 DAAM2 DENND2A DGKG DHX35 DPYSL3 EPHA7 FBXO30 FNBP1 FOXF2 FOXP1 GPC4 HLF HOXA4 HPSE2 JPH2 KCNMB1 KIAA0753 LHCGR LSM11 MYH11 MYL9 MYLK NKX6-1 NRP2 NTN1 PALLD PGM5 PLEKHO1 PPP1R12A PRUNE2 PYGB RBPMS RGMA RGMB RGS2 S1PR3 SEMA3A SEMA3E SGMS2 SLITRK3 SMTN SYDE2 SYNM SYNPO2 TPBG TRPC6 TTC23 WLS ZNF503 Esophagus - Mucosa Female 60-69 Up A2ML1 ADH7 ALDH3A1 ANXA1 BARX2 CALML3 CAPN1 CAPN14 CD164L2 CLIC3 CNFN CRABP2 CRCT1 CRNN CSTA CSTB CYSRT1 DEFB104B DHRS1 DSC2 DSG3 ECM1 EMP1 ENDOU EPHA1 EPHA2 EPS8L1 ERO1A EVPLL FABP5 FAM110C FAM83A FUT3 FUT6 GBP6 GIPC1 GJB2 GNA15 GPR78 GSTP1 IL1RN KLK10 KLK13 KRT13 KRT15 KRT4 KRT78 LEXM LY6D LYPD2 MAL MALL MPZL2 MUC21 NMU OTOP3 PADI1 PAX9 PITX1 PPL PRSS22 PRSS27 PTK6 RAB25 RABGGTA RAET1E RAET1L RHCG RHOD RHOV RIPK4 RNF222 RNF223 S100A14 S100A16 S100A2 S100A8 SERPINB13 SFN SIM2 SMAGP SOX15 SPRR2A SPRR3 TBX6 TGM1 TGM3 TMEM184A TMEM40 TMPRSS11A TMPRSS11B TMPRSS4 TRIM16 TTC22 TTC9 TTLL12 TXN TXNDC17 VSIG10L ZNF185 Esophagus - Gastroesophageal Junction Female 60-69 Up ANTXR2 CACNB2 COL4A5 COL4A6 DEFB124 FGL2 FOXF2 HOXA4 HOXB4 KCNMB1 MAMDC2 MYOC NKX6-1 NRP2 P2RX2 SEMA3A SEMA3E SHISA3 SYNM Stomach Female 60-69 Up A4GNT ADA ADAM28 AGR2 AKR1B10 AKR7A3 ALDH1A1 ANKRD22 ANXA10 ARL14 ARSD ASAH2 ATP4A ATP4B B4GALNT3 BAIAP2L1 BARX1 C9ORF152 CA2 CA9 CAPN13 CAPN8 CAPN9 CCKAR CCKBR CHGA CHIA CLDN18 CLIC6 CTSE CXCL17 CYP2S1 CYSTM1 EPN3 ESRRB ESRRG FER1L6 FMO5 FOXA2 FOXA3 FOXQ1 FRMD1 GBGT1 GCNT4 GHRL GKN1 GKN2 GPER1 GPR155 GPRC5C GRP KCNE2 KCNQ1 KPNA7 LIPF LIPH MCIDAS MECOM MFSD4A MUC1 MUC5AC MUC6 MYH13 MYRF NBPF12 PALM3 PDILT PGA3 PGA4 PGA5 PGC PIK3C2G PSCA PTGDR2 RASSF6 RFLNA RFX6 S100P SLC26A9 SLC4A2 SLC5A5 SLC7A3 SLC9A1 SLC9A3 SLC9A4 SSTR1 SULT1C2 TFF1 TFF2 TMED6 TMEM92 TOX3 TPCN2 TRIM50 TRIM73 TRIM74 VSIG1 VSIG2 VWA2 XYLT2 Skin - Sun Exposed (Lower Leg) Female 60-69 Up AADACL2 ABCA12 ABHD12B ACER1 ADGRF2 ADGRF4 ALOX12B ALOXE3 ANKRD35 ASPRV1 ATP6V1C2 BPIFC C1ORF68 C2CD4D C3ORF52 C6ORF15 CALML5 CASP14 CDHR1 CDSN CLDN1 CLEC2A COL17A1 CTNNBIP1 CYP4F22 DEGS1 DLX3 DLX5 DMKN DSC1 DSG1 DSP EFNA3 ELOVL4 FAM110A FAM83G FGF22 FLG FLG2 GJB3 GJB4 GSDMA HOPX HS3ST6 IFFO2 IL36RN IL37 KLC3 KLK5 KLK7 KLRF2 KPRP KRT10 KRT2 KRT23 KRT80 KRTDAP LAMB4 LCE1A LCE1B LCE1C LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE4A LCE5A LCE6A LGALSL LIPM LY6G6C NIPAL4 NLRP10 OR10A6 PERP PKP1 PLA2G4E POF1B PSAPL1 RORA SAPCD1 SBSN SDR9C7 SERPINA12 SERPINB7 SERPINB8 SP5 SYT8 TGM5 THEM5 TINCR TMEM45A TMPRSS13 TUFT1 UNC93A WFDC5 XG XKRX Pituitary Female 60-69 Up ALK ARC ARFGAP1 ARHGAP36 ARMCX2 ASIC4 BAIAP3 BPIFB4 C14ORF39 C21ORF58 C21ORF62 C2ORF15 CBARP CDKN2A CDRT4 CEP126 CFAP47 CFC1 CGA CHD5 CHGB CHST8 CITED1 CNGA3 COL11A2 COL22A1 COL6A6 COL9A2 CSH1 CSHL1 CUL7 DLK1 DRD2 FAM163A FBXO16 FFAR4 FOXO6 FSHB GAGE10 GCK GH1 GHRHR GHSR GJB7 GNB3 GNRHR GPR148 GPR50 GRM6 HTATSF1 IGSF1 INSM1 KSR2 LHB LHX3 LRP2BP MYO15A NEUROD4 NNAT NPW OR13C2 OR13C5 OR13C9 OTOS PCDHB1 PCSK1N PHF21B POU1F1 PRL PROP1 PTPRN QSOX2 RAX RAX2 REC8 RIIAD1 RIMBP2 RPH3AL RXRG SIX6 SSTR5 SYNGAP1 TAC4 TCP11X1 TCP11X2 TGFBR3L TMEM244 TMEM61 TRHR TRPC3 UBTFL1 UNC79 VMO1 VWA5B1 VWA7 VWDE ZFR2 ZNF10 ZNF667 ZP1 Brain - Cerebellum Female 60-69 Up ABCG4 AKAIN1 ALS2 ARHGEF33 BARHL1 BARHL2 CACNA1A CACNA1G CACNG2 CARMIL3 CCDC175 CECR2 CELSR3 CKMT1B CLVS2 CNPY1 CRTAM DAO DISP2 EN2 FAM131C FAT2 FGF17 FUT9 GALNT9 GNG13 GOLGA7B GRID2 GRIN2C GRM4 IFNA8 IGLON5 KCNAB3 KCNC1 KCNK9 KLHL3 LCN8 LHX1 MCF2L MDGA1 MEGF11 MMP24 MTCL1 MYT1 NBPF20 NEUROD1 NKX6-3 NPFFR1 OR1F1 OTX2 PAX6 PKD1 PLEKHD1 PLK5 PPFIA4 PRR35 PRRT2 PRSS51 PVALB RAB26 RBFOX3 RGS11 SBK1 SCRT2 SHF SHISA8 SKOR1 SLC1A6 SLC22A31 SLC35F4 SRRM3 SRRM4 ST8SIA5 STRC TENM1 TFAP2E TLX3 TMC2 TMEM132E TMEM145 TMEM151B TMEM178A TMEM266 TNFRSF25 TRIM11 TRIM67 TRIM9 TRPM3 UNCX VAX2 VSX1 WSCD2 XKR7 YPEL4 ZFYVE28 ZIC2 ZIC3 ZIC4 ZIC5 ZNF382 Whole Blood Female 50-59 Up ADAM8 ADGRE2 ADGRE3 ADGRG3 ADIPOR1 AOAH APBB1IP APOBR AQP9 ARHGAP25 ARHGAP45 ARHGAP9 ARRB2 BIN2 C5AR1 CD300A CEACAM3 CSF3R CST7 CXCR1 CXCR2 CYTIP DHX34 DOK3 EPB42 EVI2B FCAR FCGR2A FCGR3B FCN1 FGD3 FMNL1 FPR1 FPR2 GATA1 GMIP GPSM3 GRK6 HBA2 HBD HBQ1 HCAR2 HCAR3 IFITM2 IL18RAP IL2RG ITGAM ITGAX ITGB2 KCNJ15 KIR2DL4 KIR3DL1 LAPTM5 LCP1 LCP2 LILRB3 LITAF LRRC25 LSP1 LYN MEFV MFSD2B MPP1 MXD1 MYO1F NCF2 NCF4 PADI4 PIK3R5 PILRA PRAM1 PROK2 PSTPIP1 PTPRC R3HDM4 RAC2 RASGRP4 RHOG RNF24 SELL SELPLG SIGLEC5 SIRPB1 SLA SLC25A37 SPI1 SRGN TAGAP THEMIS2 TLR2 TMEM71 TNFRSF10C TNFRSF1B TREM1 TRIM58 VAV1 VNN2 WAS XPO6 ZDHHC18 Cells - Cultured Fibroblasts Female 50-59 Up ADAM9 ADAMTS6 ADAMTSL1 ALDH1L2 ANXA2 ANXA5 ARSJ ASCC3 BMPER C6ORF120 CALU CCBE1 CD109 CKAP4 CLEC11A COL1A1 COL1A2 COL5A2 COL6A3 CTHRC1 DCBLD2 DKK1 DSEL DUSP10 EDA2R EIF2AK4 EMC1 FAP FBN1 FBN2 FGF5 FKBP10 FN1 FRMD6 GALNT5 GANAB GCNT1 GNPNAT1 GPR176 GPX8 GREM1 HIF1A HMGA2 HOXC8 HS3ST3A1 HS3ST3B1 IGF2BP2 IGF2BP3 IKBIP KCNK2 KDELR3 LGALS1 LOX LOXL2 MME MYOF NECTIN3 NT5E P4HA2 PAPPA PCDH18 PCDHGA11 PCDHGA12 PCDHGB4 PCOLCE PDIA6 PLOD1 PRR16 PRSS12 PSG1 PSG5 RCN1 RCN3 RECK RRAS2 SEC22B SERPINE2 SNAI2 SRGAP1 STEAP1 STEAP1B STT3A TICAM2 TNFRSF10D TNFSF4 TNPO1 TRAM1 TRAM2 TRNP1 TRPA1 TWIST1 TWIST2 TXNRD1 UGGT1 ULBP1 ULBP3 VGLL3 WNT5A XPOT YIPF5 Thyroid Female 50-59 Up AFAP1L2 ATP13A4 BMP8A C16ORF89 CLN5 COL23A1 CPQ CRYGN CTSB CYTH2 DAPK2 DIO1 DUOX2 EPOR EXOC3L2 FLT4 FOXE1 FRAS1 FREM2 FSCN2 GAL3ST3 GFRA2 GOLGA8M GOLGA8Q GOLGA8R GRK1 HHEX HIRA HOOK3 IFT140 IL15 INPP5J IQCA1 ISM1 IVD IYD KCNC3 KCNJ16 KLHL14 KNSTRN LCN12 LIPG LIPI LPCAT2 LRP2 MGAT4C MPPED2 MROH1 MSANTD2 MT1F MUC15 NKX2-1 NPNT OR2A1 PABPC1L PAX8 PBX4 PDE8B PKHD1L1 PLA2G6 PLA2R1 PLEKHH1 PLVAP PPP1R13B PRKX PRTG RCBTB1 RGL3 RHPN1 S100A5 SALL1 SALL4 SCX SHISA2 SLC12A8 SLC16A11 SLC17A5 SLC25A29 SLC26A4 SLC26A7 SLC4A11 SLC5A8 SNX1 SNX22 SORD SUCNR1 TFF3 TG TPMT TPO TRIB1 TSHR VEGFA WDR72 ZBED2 ZNF114 ZNF486 ZNF737 ZNF804B ZNF90 Adipose - Visceral (Omentum) Female 50-59 Up ADAMTS15 ADAMTS4 ADAMTS9 ADGRL4 ADIPOQ AGPAT2 AIFM2 AKAP12 ALDH1A3 ALOX15 APOLD1 AQP7 ARHGEF15 BTNL9 CCDC71L CCNL1 CD209 CD300LG CD36 CD93 CDC42EP4 CH25H CLEC10A CPXM1 DCUN1D3 DLC1 DUSP6 EDNRB F13A1 F8 FABP4 FAM110D FAM89A FGF10 FOLR2 FZD4 GAS1 GFPT2 GNAT3 GPBAR1 GPR4 GYG2 HAS1 IL10 ITLN1 KDR LPL LRRN4 LXN LYVE1 MAP3K8 MEDAG MEST MGST1 MMP19 MRC1 MSLN MT1A MT1E MT1M MUC16 MYC NMB NOTCH4 NWD2 OR2B11 OR52N1 OR52N5 PDPN PIM1 PLAU PLTP PLXNA4 PNPLA2 PPARG PPP1R15B PRKAR2B PROCR PRRT4 RARRES1 RBP7 SERPINE3 SIGLEC1 SLC19A3 SLC7A10 SMIM3 SOCS3 SOX17 SPAAR SRPX SRPX2 TIE1 TIMP4 TMEM132C TMEM88 TSHZ2 UPK3B VSIG4 VWF WNT11 Esophagus - Muscularis Female 50-59 Up ABCC1 ACTG2 ACTN1 ADCY5 ADRB3 ANKS1A ANTXR2 ARHGAP10 ARHGEF26 ARMC9 ARSB BCHE CACNA1H CACNB2 CALD1 CCDC69 CHRM3 CNN1 CNTNAP3 COL4A5 COL4A6 CYSLTR1 DAAM2 DENND2A DES DGKG DHX35 DMPK DPYSL3 EML1 EPHA7 FAM83D FBXO30 FLNA FNBP1 FOXF1 FOXF2 FOXP1 GIPC3 GPC4 HLF HOXA4 HOXB2 HOXB4 HPSE2 IGSF9B INPP5A ITGA1 JPH2 KANK2 KCNMB1 KCNQ4 KIAA0753 KLHL23 KLHL42 LHCGR LPP LSM11 MYH11 MYL9 MYLK NKX6-1 NRP2 NTN1 OCRL PALLD PARVA PGM5 PLEKHO1 PPP1CB PPP1R12A PPP1R12C PRUNE2 PYGB RARB RBPMS RGMA RGMB RGS2 RSPO3 S1PR3 SCUBE1 SEMA3A SEMA3E SGMS2 SLC27A6 SLC2A12 SLITRK3 SMTN SORBS1 SRF SYDE2 SYNM SYNPO2 TPBG TRPC6 TTC23 WLS WWTR1 ZNF503 Esophagus - Gastroesophageal Junction Female 50-59 Up ACTG2 ADCY5 ANKS1A ANTXR2 ARHGAP10 ARMC9 BARX1 BCHE BTC CACNA1H CACNB2 CALD1 CHRM3 CNN1 COL4A5 COL4A6 CYSLTR1 DGKG DMPK DNAJB5 EML1 FBXO30 FGL2 FLNA FOXF1 FOXF2 FOXP1 GPC4 GRPR HOXA3 HOXA4 HOXB4 HPSE2 HS1BP3 INPP5A ISL1 JPH2 KANK2 KCNMA1 KCNMB1 KCNQ4 KLHL42 LSM11 MAGEB17 MAMDC2 MAP3K20 MEIS1 MRGPRF MYH11 MYL6 MYL9 MYLK MYOC NKX6-1 NRP2 NTN1 OCRL PALLD PDZRN3 PGM5 PLEKHO1 PPP1R12A PPP1R12C PRUNE2 RBPMS RGMB ROR2 RSPO2 RSPO3 S1PR3 SCUBE1 SELENOM SEMA3A SEMA3E SMTN SYNM TACR2 TEAD3 TGFB1I1 TOX2 VIPR2 WLS Vagina Female 50-59 Up AADACL4 ADAM33 ADAMTSL5 ALOX12 AR BARX2 BDKRB2 C16ORF74 CNFN CPA6 CRABP2 DIO3 DSC2 EDN2 EDN3 EPHA1 ERVV-1 ESR1 EVPLL EVX1 FABP5 FAM83A FBLN1 GJB2 GJB6 GOLGA6L9 HCG22 HOXA13 HOXD10 HOXD11 HOXD12 HOXD13 HOXD9 IGDCC4 ISL1 ISL2 IVL KRT6A LCE3A LCE3D LCE3E LPAR6 MASP1 MATN2 MPZL2 NUAK2 NXNL2 OSR2 PI16 PRSS12 RAET1E RHCG RNF223 RSPO1 SALL3 SERPINB12 SERPINB13 SERPINB3 SERPINB4 SFRP1 SOX7 SPINK5 SPINK7 SPRR1A SPRR1B SULT1E1 TBX6 THSD4 TMPRSS11A TMPRSS11D TMPRSS11E TPRG1 UPK1A Uterus Female 50-59 Up ACSM3 ADAM33 ADAMTS19 ADAMTSL5 ALDH1A2 ALX3 AR ATP8B4 AXIN2 B3GLCT BCL9 BNC2 BTBD19 CAPN6 CCDC171 CDH24 CDKL1 CEP135 DCHS1 DET1 EMX2 ENPP1 EPHB4 ESR1 FREM1 FRMD7 GAS1 GATA2 GPR161 GUCY1A2 HOXA10 HOXA11 HOXA6 HOXD10 HOXD11 HOXD3 HOXD4 HOXD9 IL17RD ISLR ISOC1 KCNG1 KLHL13 LEFTY2 LINGO2 LONRF2 MAMDC2 MASP1 MATN1 MEIS1 MEIS2 MEIS3 MEX3A MITF MOXD1 NXNL2 OSR2 PAWR PBX1 PGR POMGNT2 PRLR PTGER3 PTK7 RAB11FIP2 RAD51B RAMP1 RAP2C RERG RPRM RSPO1 RXFP2 SERTM1 SLC24A3 SLC37A3 SLC7A3 SMO SNCAIP SPEF2 STK26 SULF2 SYTL4 TAB3 TBC1D1 TBL1X TCEAL1 TCEAL4 TCF23 TEX15 TMEM200A TMEM200B TNFAIP8L3 TRPC4 USP31 WT1 XKR5 ZBTB12 ZCCHC12 ZNF496 ZNF516 Skin - Sun Exposed (Lower Leg) Female 50-59 Up AADACL2 ABCA12 ACER1 ADGRF2 AHNAK2 ALOX12B ALOXE3 ASPRV1 C1ORF68 C6ORF15 CALML5 CASP14 CDSN CLDN1 CLEC2A COL17A1 CTNNBIP1 CYP4F22 DAPL1 DEGS1 DLX3 DLX5 DMKN DSC1 DSG1 DSP EFNA3 EPHB3 EPPK1 EXPH5 FAM110A FAM83G FLG FLG2 GJB3 GSDMA HOXC12 HS3ST6 IFFO2 IL36B IL36RN IL37 KCNK7 KLC3 KLK5 KLK7 KLK9 KLRF2 KPRP KRT10 KRT14 KRT2 KRT80 LAMB4 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE4A LCE5A LCE6A LGALSL LIPM LY6G6C LYPD5 MYCL NIPAL4 NLRP10 PERP PKP1 PLA2G4E POF1B PSAPL1 RDH12 RORA SBSN SDR9C7 SERPINA12 SERPINB7 SLC46A2 SYT8 TGM5 THEM5 TINCR TMEM45A TMEM86A TMPRSS13 TRIM35 TUFT1 UNC93A WFDC5 XG XKRX ZNF750 Muscle - Skeletal Female 50-59 Up ABLIM2 ACTN2 ALPK3 ANKRD23 ART1 ART3 ASB12 ASB16 ASB2 ASB8 BIN1 C10ORF71 CACNG1 CACNG6 CAND2 CAP2 CAPN3 CHRNA10 CHRNB1 CKM CLTCL1 CMYA5 COQ8A DCAF6 DUSP13 EEF1A2 EGLN1 EYA4 FEM1A FHL3 FXR1 GMPR IDI2 IP6K3 JPH1 JSRP1 KCNA7 KCNJ11 KLHL30 KLHL34 KLHL38 KLHL40 KLHL41 LBX1 LINGO4 LRRC2 MACROD1 MAPK12 MKNK2 MRLN MYBPC1 MYF6 MYO18A MYO18B MYOZ1 MYPN NEB OBSCN OPTN OSBPL11 PCNT PDE4DIP PFKM PGM1 PHKG1 PITX3 POPDC3 PRKCQ PROB1 PYGM RAD23A RAPSN RNF123 RPL3L RYR1 SH3BGR SIX4 SLC29A2 SMTNL2 SPTB STAC3 SYPL2 TBX15 TMEM38A TMOD4 TNNT1 TPM3 TRDN TRIM54 TRIM63 TRIM72 TTN TXLNB UBAC1 UCP3 USO1 USP13 UTP11 YBX3 ZNF106 Pituitary Female 50-59 Up ALK ARFGAP1 ARHGAP36 ASIC4 BAIAP3 BPIFB4 C14ORF39 C2CD4A C2ORF15 CDKN2A CDRT4 CERK CFAP47 CFC1 CGA CGB3 CGB5 CHGB CHST8 CITED1 CNGA3 COL11A2 COL22A1 CRYBA2 CSH1 CSH2 CSHL1 DGKK DLK1 DMRTC1B DRD2 FAM163A FBXO16 FFAR4 FOXO6 FSHB GAGE10 GAL GCK GH1 GHRHR GHSR GJB7 GJD2 GNAS GNB3 GNRHR GPR148 GPR50 HTATSF1 HTN3 IGSF1 INSM1 KSR2 LHB LHX3 MYO15A NEUROD4 NLRP1 NNAT NPTX2 OR13C2 OR13C9 OTOS PCDHB1 PCSK1N PHF21B PLD3 POMC POU1F1 PRL PROP1 PTPRN RAX2 REC8 RIIAD1 RIMBP2 RPH3AL RTBDN SCG5 SIX6 SSTR5 TAC4 TBX19 TCP11X2 TGFBR3L TMEM244 TMEM61 TPH2 TRHR TRPC3 UBTFL1 VMO1 VWA7 VWDE ZBTB8B ZFR2 ZNF10 ZNF667 ZP1 Pituitary Male 60-69 Up ADGRD2 ARFGAP1 ARHGAP36 ASCL1 ASIC4 AVPR1B BAIAP3 BPIFB3 C14ORF39 C17ORF107 C21ORF58 C2CD4A C2ORF15 CBARP CDKN2A CDRT4 CFAP47 CFC1 CGA CHGB CHST8 CNGA3 COL11A2 COL22A1 COL9A2 CRHR2 CSHL1 DGKK FAM163A FBXO16 FFAR4 FOXO6 GAGE10 GAL GALR1 GCK GH1 GHRHR GHSR GJB7 GJD2 GNAS GNB3 GPR50 HFM1 HTATSF1 IGSF1 INSM1 KCNH6 KSR2 LHB LHX3 LMX1A MYO15A NAT16 NEUROD4 NLRP1 NNAT NPTX2 OR10G3 OR13C2 OTOS PCDHB1 PCSK1N PHF21B PLD3 POMC POU1F1 PRL PRLHR PROP1 PTPRN REC8 RIIAD1 RIMBP2 RNF224 RPH3AL RTBDN SCG5 SIX6 TAC4 TBX19 TCP11X1 TCP11X2 TGFBR3L TMEM244 TMEM61 TPH2 TRHR TRPC3 TSHB UGT2A1 VWA7 VWDE ZBTB49 ZFR2 ZNF10 ZNF667 ZP1 ZSCAN1 Whole Blood Male 50-59 Up ACAP1 ADAM8 ADGRE3 ADGRG3 ADIPOR1 AOAH APBB1IP APOBR ARHGAP45 ARHGAP9 ARRB2 BIN2 C5AR1 CD300A CD300C CD300LB CEACAM3 CFP COTL1 CSF3R CST7 CTSS CXCR1 CYBA CYTH4 CYTIP DHX34 DOK2 FCN1 FERMT3 FFAR2 FGD3 FGR FKBP8 FMNL1 FPR1 GATA1 GMIP GPSM3 GRK6 GYPC HBA1 HBA2 HBB HBD HBM HCK ICAM3 IL2RG ITGAM ITGAX ITGB2 LAPTM5 LCP1 LCP2 LILRA1 LILRA2 LILRB2 LILRB3 LIMD2 LRRC25 LSP1 MEFV MPP1 MYO1F NCF2 NCF4 NFE2 PADI4 PHOSPHO1 PIK3R5 PILRA PLBD1 PRAM1 PSTPIP1 R3HDM4 RAC2 RASGRP4 RELT RHOG RIN3 SELL SELPLG SH3BGRL3 SHKBP1 SIRPB1 SLC25A37 SLC25A39 SPI1 TAGAP TBC1D10C THEMIS2 TNFRSF1B TREM1 TYROBP VAV1 VSIR WAS XPO6 ZDHHC18 Cells - Cultured Fibroblasts Male 50-59 Up ADAM12 ADAM9 ADAMTS2 ADAMTS6 ALDH1L2 ANXA2 ANXA5 ARSJ ASCC3 C6ORF120 CALU CCBE1 CCDC80 CD109 CHML CKAP4 CLEC11A COL12A1 COL1A1 COL1A2 COL5A2 COL6A3 CTHRC1 CXCL5 DCBLD2 DKK1 DSEL DUSP10 EDA2R EIF2AK4 EMC1 FAP FBN1 FGF5 FKBP10 FKBP14 FN1 FRMD6 GCNT1 GNPNAT1 GPR176 GPX8 GREM1 HAS2 HIF1A HMGA1 HMGA2 HOXC8 HS3ST3A1 HS3ST3B1 IGF2BP2 IGF2BP3 IKBIP KCNK2 KDELR3 LGALS1 LMNB2 LOX LOXL2 MME MYOF NECTIN3 NT5E PAPPA PCDH18 PCDHGA11 PCDHGA12 PCDHGB4 PCOLCE PLOD1 PLOD2 PRR16 PTX3 RAI14 RCN1 RCN3 RECK SEC22B SERPINE1 SNAI2 SRGAP1 SSR3 STEAP1 STEAP1B STT3A TGFBI THBS1 TMEM119 TNFRSF10D TNPO1 TRAM1 TRAM2 TRNP1 TWIST1 TWIST2 ULBP3 VGLL3 WNT5A XPOT YIPF5 Artery - Aorta Male 50-59 Up ADAMTSL3 ADRA1B ADRA2C AEBP1 ANO1 ANTXR1 ASPN BGN C1QTNF2 C1QTNF8 C8ORF34 CD151 CDH13 COL14A1 COL21A1 COL8A1 COL8A2 CPXM2 CRISPLD1 CYTL1 EFEMP1 ELN EXT1 FAM180A FBLIM1 FBLN5 FMOD FOXC1 FOXC2 FRZB GAS6 GDF7 GLIPR1 HAPLN3 HAUS7 HMCN1 IGFBP2 IGFBP7 IL31RA ITGA10 ITGA11 ITGA8 ITGB5 KALRN KANK1 KCNK15 KCNK17 LDOC1 LGR6 LIMS4 LOXL1 LTBP1 LTBP2 LTBP3 MEGF6 MFAP4 MFGE8 MGP MRAP2 MYH10 MYH9 MYO1D NAV2 NOX4 NPR1 NXPH3 OGN OMD PCDH11X PCDH7 PDGFA PDGFD PID1 PKD2 PLD5 PLS3 PMEPA1 PRDM16 PRDM6 PRELP PRKG1 PTGIR PXDC1 SMOC2 SOD3 SOST ST6GAL2 STAC STK38L SUGCT SULF1 SUSD5 TBXA2R THBS2 TMEM47 TNFRSF11B TPH1 VCAN WWP2 ZNF385D Heart - Left Ventricle Male 50-59 Up ACO2 ACTC1 ASB18 ASIP BCO2 BSG BZW2 CASQ2 CCDC141 CDH2 CHCHD10 CKMT2 COQ10A COX5A COX6A2 COX7A1 COX7B CPT1B CRYAB CSDC2 CSRP3 DAND5 DDO DECR1 ECSIT EIF1AY EIF1B ETFDH FABP3 FGF18 FHL2 FHOD3 FITM2 GJA3 GOT1 HHATL HRC HSPB3 HSPB7 ITGB1BP2 KLHL31 LDHB LRRC10 LSMEM2 MAPKAPK3 MDH1 MFN2 MLYCD MPC1 MT1HL1 MTUS2 MYBPC3 MYH7 MYH7B MYL2 MYL3 MYLK3 MYOM2 MYOZ2 MYZAP NDUFA1 NDUFAB1 NDUFS6 NEBL NKX2-5 OGDH PDE1C PDHA1 PKP2 PLN POPDC2 PPM1K RBM20 RD3L RYR2 S100A1 SCN5A SDHA SGCG SLC25A30 SLC25A4 SLC41A1 SLC4A3 SLC8A1 SMCO1 SMPX SMYD2 SRL SYNPO2L TCF15 TECRL TENM2 TLL2 TMEM182 TNNI3 TNNI3K TNNT2 TPM1 UQCRC1 UQCRQ Heart - Atrial Appendage Male 50-59 Up ACTC1 ADAMTS7 ADAMTSL2 ALPK2 ANKRD1 ASPG BCO2 BMP10 C14ORF180 CASQ2 CCDC141 CHRNE CIB2 CORIN CRIP2 CSDC2 CYCS CYP2J2 CYSLTR2 DAND5 DHRS7C DKK3 DOK7 EIF1AY ENG FABP3 FBLN2 FBXO40 FGF12 FITM2 GATA4 GRXCR2 HCN4 HHATL HRC HSPB2 HSPB3 HTRA3 IGSF5 ITGB1BP2 KCNIP2 KLHL31 KRBA1 LAPTM4B LRRC10 METTL7B MT1HL1 MTUS2 MYBPC3 MYBPHL MYH6 MYL4 MYL7 MYLK3 MYOZ2 MYZAP NDUFAB1 NEBL NES NKX2-5 NMRK2 NPPA NPPB NRTN OR10P1 OR8B8 OTOGL PAM PCOLCE2 PLA2G5 POPDC2 PRKAG2 PRR32 PXDNL RABGAP1L RBM20 RBPMS2 RD3L RILPL1 RYR2 S100A1 SBK2 SBK3 SCN5A SHD SLC25A4 SLC41A1 SLC4A3 SLC8A1 SSTR5 SYNPO2L TBX20 TBX5 TECRL TMEM182 TNNI3K TNNT2 TRIM55 UQCRB WNK2 Skin - Sun Exposed (Lower Leg) Male 50-59 Up AADACL2 ABCA12 ACER1 ADGRF2 ADGRF4 ALOX12B ALOXE3 ANKRD35 BPIFC C1ORF68 C2CD4D C3ORF52 CA6 CALML5 CARD14 CASP14 CASZ1 CD207 CDHR1 CDSN CLEC2A CTNNBIP1 CYP4F22 DEGS1 DLX3 DLX5 DMKN DSC1 DSC3 DSG1 DSP EFNA3 EPHB3 EXPH5 FAM83B FAM83C FLG FLG2 FOXN1 GJB4 GSDMA HELT HS3ST6 IDE IFFO2 IGFL2 IGFL3 IL36B IL36RN IL37 KCNK7 KLC3 KLK5 KLK7 KLRF2 KPRP KRT1 KRT10 KRT2 KRT80 LCE1A LCE2A LCE2B LCE4A LCE5A LCE6A LGALSL LIPM LY6G6C LYPD5 NIPAL4 NLRP10 PARD6G PERP PKP1 PLA2G2F PLA2G4E PLA2G4F PNPLA1 POF1B POU2F3 PSAPL1 RDH12 SAPCD1 SBSN SDR42E1 SDR9C7 SERPINA12 SERPINB7 SLC39A2 TFAP2A TGM5 THEM5 TINCR TMEM45A TMPRSS13 TUFT1 UNC93A XKRX ZNF750 Artery - Tibial Male 50-59 Up ACAN ACTA2 ACTN4 ADARB1 ADIRF AEBP1 ALDH1B1 AMIGO2 ARHGEF17 ARHGEF39 BCAM C11ORF96 C12ORF75 CCDC3 CDH6 CHSY3 CLIC4 CNTN4 COL14A1 COL18A1 COMP CPED1 CRLF1 CSPG4 CSRP2 DACT3 DSTN EFHD1 ENAH FBLIM1 FHL5 FLNA FOXC1 FOXC2 FOXL1 FRY GPR20 HEY2 HSPG2 HTR1B ID2 IGFBP7 IGFBPL1 ITGA5 JAG1 JAK2 KCNA5 KCNAB1 KCTD10 KLHL26 LMOD1 LPP MCAM MSRB3 MUSTN1 MYL9 MYO1D NKD1 NOTCH3 NTF3 NTRK3 P2RX1 PDK3 PLEKHG3 PLS3 PMEPA1 PPP1R14A PRELP PRKG1 RASL12 RASSF3 RCAN2 RERGL RHOB RNF180 ROCK1 ROR1 RRAS RSU1 SDK1 SFRP2 SH3BGRL SMAD7 SMIM10 SORBS2 SPEG SUSD5 TAGLN TASP1 TBX18 TBXA2R TGM2 TLN1 TMEM181 TMEM47 TNS1 TRABD2B USP35 WTIP ZFHX3 Pituitary Male 50-59 Up ADGRD2 ALX3 ARFGAP1 ARHGAP36 ASCL1 ASIC4 AVPR1B BAIAP3 BPIFB3 BPIFB4 C14ORF39 C17ORF107 C21ORF58 C2ORF15 CDKN2A CFAP47 CFC1 CGA CHGB CHST8 CLDN9 CNGA3 COL11A2 COL22A1 COL9A2 CRHR1 CRHR2 DGKK DMRTA2 FAM163A FBXO16 FFAR4 FOXO6 GAGE10 GAL GALR1 GCK GH1 GHRHR GHSR GJB7 GJD2 GNAS GNB3 HFM1 HTATSF1 IGSF1 INSM1 IRS4 KCNH6 KSR2 LHB LHX3 LMX1A MDK MYO15A NAALAD2 NEUROD4 NLRP1 NNAT OR10G3 OR13C2 OTOS PCDHB1 PCSK1N PHF21B PLD3 POMC POU1F1 PRL PRLHR PROP1 RAX2 REC8 RIIAD1 RIMBP2 RNF224 RPH3AL RTBDN SCG5 SIX6 TAC4 TBX19 TCP11X1 TCP11X2 TGFBR3L TMEM244 TMEM61 TRHR TRPC3 TSHB UGT2A1 UGT2A2 VWA7 VWDE ZFR2 ZNF10 ZNF667 ZP1 ZSCAN1 Breast - Mammary Tissue Male 50-59 Up ADAMTS3 ADCY4 ADGRL4 ADRB2 ANGPT4 ANKRD30A ARHGAP40 ARHGEF15 BTNL9 CD300LG CD36 CLDN5 CST9 CYYR1 FABP4 FAM124B FGF10 GPIHBP1 GPR146 GSC HCAR1 INHBB KLHDC7A MEOX1 MMRN2 MYB NLRP13 NLRP8 NOTCH4 NPY2R PAPPA2 PI15 PPARG PROKR1 RAB6C RAPGEF3 RBP7 SCGB2A2 SEMA3G SPAAR STC2 TMEM26 TNN TRPS1 USHBP1 VTCN1 Artery - Coronary Male 50-59 Up AEBP1 ANTXR1 ARL4AP5 ART4 ASPN BGN C1QTNF1 CCDC3 CCL19 CFH CMKLR1 COL18A1 COL21A1 COL4A2 COL4A4 CPED1 CPXM2 CRIP1 CSRP2 CTPS1 ECM2 EFEMP1 ELN FBLIM1 FMOD FOXS1 FRK GJA5 GLIS2 GPR20 HAPLN1 HAUS7 HEYL IGFBP2 IGFBP7 IL33 ITGA10 ITGA8 ITGB5 IZUMO1R JADE1 JAG1 KALRN KCNA5 KCNK15 KCNK17 KCNT2 LGR6 LRRC17 LTBP1 LTBP2 LTBP4 MEGF6 MFAP4 MFGE8 MGP MMP23B MSC MTHFD1L MYO1D NTF3 NTRK3 OGN OMD P4HA3 PCOLCE2 PDGFA PLA2G5 PPP1R14A PRDM16 PRELP PRKG1 PTGIS SCARF2 SMIM10 SORT1 ST6GAL2 SUSD5 TBX18 TBX2 TBXA2R TGM2 THBS2 TIMP1 TINAGL1 TNFRSF11B TRABD2B VCAN WTIP Brain - Frontal Cortex (BA9) Male 50-59 Up AGBL4 AK5 ANKRD24 ATRNL1 BHLHA9 C11ORF87 C3ORF80 CABP1 CAMK2A CBLN2 CCK CHN1 CLEC2L CNTNAP2 COL26A1 CREG2 CTXN3 DLGAP1 DPP10 EIF4E1B ELAVL4 ENC1 EPHX4 FAM163B FAM81A FREM3 FRMPD4 FXYD7 GABBR2 GABRA1 GABRG2 GAP43 GLRB GRIA3 GRIN2A HAPLN4 HCN1 HECW1 HS6ST3 HTR2A HTR3B KCNC2 KCNH5 KCNS1 KCNS2 KCNV1 KCTD16 KIAA1549L LINGO1 LMO4 LRFN2 LRFN5 LRRTM4 MAPK10 MCHR2 MGAT5B MPPED1 NAP1L2 NAPB NCALD NECAB1 NEFL NEFM NELL1 NELL2 NEUROD6 NLK NPBWR2 OLFM1 OLFM3 OPRD1 OR14I1 PHF24 POU6F2 PRKAR1B PTPRT R3HDM1 RAB6B RGS4 RIMS3 RORB RPH3A RTP1 SCN1A SERPINI1 SGTB SLC4A10 SNCB SULT4A1 SYP SYT1 SYT13 SYT16 TBR1 TESPA1 TMEM132D VSNL1 VSTM2A YWHAH ZNF365 Brain - Caudate (Basal Ganglia) Male 50-59 Up ACBD7 ADORA2A AMBN ANKRD34B ANO3 AQP4 ARPP19 ARPP21 C1QTNF4 CACNG4 CHAT CHRM4 CNMD CORT CTXN1 CYP46A1 DACT2 DGKB DLX6 DRD1 ENTPD3 ETNPPL FAM171A1 FBXL16 FKBP1B GABRA2 GABRA4 GAD2 GAREM2 GNAL GNG7 GPC5 GPR139 GPR88 GRM3 GSG1L HCN2 HHIPL1 HPCA HS3ST5 HTR6 JAKMIP1 KCNH4 KCTD17 KLF16 LGI1 LINGO3 LRRC10B LRRN1 LRTM2 MAPK4 MC4R METRN MINDY4B MLC1 MMD2 NCDN NECAB2 NGEF NR2E1 NTSR2 ONECUT2 OTOF PCP4 PCP4L1 PDE10A PDE1B PLSCR5 POU3F2 POU3F4 PPP1R1B PPP3CA PRKCB PSD2 PTPN5 RASD2 RESP18 RGS14 RGS20 RGS8 RGS9 RIC8B RLBP1 RPRML SCN4B SIX3 SLC1A2 SLC24A2 SLC25A23 SLC35D3 SNN SOWAHA SP9 SPEF1 ST8SIA3 STRIP2 SYNDIG1L TAC1 TMEM158 YJEFN3 Brain - Nucleus Accumbens (Basal Ganglia) Male 50-59 Up ACTR3B AKAP5 ANKRD34B ANKRD63 ARPP21 C1QTNF4 C4ORF50 CACNA1E CACNG4 CALB1 CAMKV CDH9 CNMD COCH CPNE5 CRYM CTXN1 DACH2 DACT2 DLL3 DLX6 DRD1 DRD3 DTNBP1 EFNB3 FAT3 GABRA4 GABRA5 GABRB1 GAD2 GNAL GNG7 GPC5 GPR101 GPR149 GPR27 GPR52 GPR6 HS6ST2 HTR1D HTR2C HTR6 ICAM5 IDNK IMPG1 KCNA4 KCNH4 KCNIP1 KCNK4 KCTD4 KHDRBS2 KIRREL3 LAMP5 LINGO3 LRRC7 LRRTM1 LYPD1 MINDY4B MMD NAT16 NCDN NECAB2 NTSR2 OPRK1 OTOF PCDH11X PCDHGC5 PCP4L1 PDE1B PDE7B PDYN PENK PHACTR1 PLPPR1 PLPPR3 PNMA5 POU3F4 PRKCG PRMT8 PTPN5 RAB40B RESP18 RGS20 RGS8 RPRML SEZ6 SH2D5 SHISA7 SIX3 SLC32A1 SLC9A7 SORCS3 SOWAHA SP9 SV2C SYNPR THRA TMEM158 WNT1 WNT10B Brain - Putamen (Basal Ganglia) Male 50-59 Up ADORA2A AMBN AMER2 ANO3 ARPP19 ARPP21 ASIC1 ASPHD1 BAALC C1QTNF4 CABLES1 CACNG4 CERCAM CHAT CNDP1 CORT CPLX1 CST3 CTXN1 CYP46A1 DACT2 DGKB DLX6 DRD1 DRD2 EFR3B ENHO ENTPD3 ETNPPL EYA1 FAM171A1 FBXL16 GAREM2 GBX2 GNG7 GPC5 GPR37L1 GPR6 GPR85 GPR88 GPRC5B GRM3 HAGHL HCN2 HDAC11 HHIPL1 HPCA HRH3 HS3ST5 HTR6 KCNF1 KCNH4 KCNJ10 KCNJ14 KCTD17 LRRC10B LRTM2 MEGF10 METRN MLC1 MT3 NGEF NRGN OLFM2 OLIG2 ONECUT2 OPALIN OTOF PCP4 PDE10A PDE1B PPP1R1B PPP3CA PSD2 PTPN5 QDPR RASD2 RESP18 RGS14 RGS20 RGS9 RLBP1 RPRML SCN4B SFXN5 SIX3 SLC18A3 SLC1A2 SLC24A2 SLC25A23 SLC6A12 SP9 SPEF1 ST8SIA3 SYNDIG1L TAC1 TMEM158 TMEM235 TRIL TTYH1 Brain - Hypothalamus Male 50-59 Up ACHE ADCYAP1 AIRE ANKRD34C AVP B3GAT2 B4GAT1 CALB2 CALCB CALCR CALY CBLN4 CNGB1 CSMD3 CTXN2 CXXC4 DIRAS3 DLX1 DNER ECE2 ECEL1 ERAS FEZF1 FNDC9 FOXB1 GABRA3 GABRG3 GABRQ GLRA1 GLRA2 GRIK1 GRIN2D GRIN3A GRM7 GSX1 HAP1 HCRT HCRTR2 INPP5F INSM2 KISS1R KLHL1 LHX5 LRRC55 LUZP2 LY6H MAGEL2 MC4R NAP1L3 NAP1L5 NGB NPSR1 NXPH1 OPRK1 PABPC1L2A PABPC1L2B PCDH11Y PCDH19 PCSK1 PEG3 PIRT PLPP4 PNMA2 PNMA5 PRDM12 PRDM13 RAB3B RAB3C RND2 RPE65 RTL1 RTP5 SCG2 SCN3A SCN9A SEZ6L SLC17A6 SLC6A11 SMIM10L2B SMIM17 SMIM18 SNCG SOX1 SOX11 SOX14 SST SYNGR3 TACR3 TMEM114 TMEM17 TMEM196 TMEM255A TMEM35A TUBB3 VAT1L VGF VSTM5 VWC2L ZBTB8B ZCCHC12 Brain - Spinal Cord (Cervical C-1) Male 50-59 Up ABCA2 AGPAT4 ANLN APLP1 BACE1 BCAS1 C21ORF91 CA14 CARNS1 CDK18 CHADL CHRM5 CLDND1 CMTM5 CNDP1 CNP CNTN2 CNTNAP4 CTNNA3 DBNDD2 DPYSL5 DTNB EDIL3 ENPP6 ERMN EVI2A FA2H FEZ1 FGFR2 FMNL2 FNTB GAL3ST1 GFAP GJC2 GPM6B GPR37 GPR62 HAPLN2 HMSD HOXD1 KCNJ10 KLK6 LANCL1 LHPP LLGL1 LRRC63 MAG MAP7 MARCKSL1 MBP MOB3B MOBP MOG MTMR10 MTURN MVB12B MYRF NIPA1 NKAIN2 NKX2-2 NKX6-2 OR9A2 PACS2 PAQR4 PAQR6 PAQR8 PCSK6 PEA15 PEX5L PIP4K2A PKP4 PLEKHB1 PLP1 PRRG1 RAPGEF5 RASSF2 RBM11 RNF13 S100B SEC14L5 SEMA4D SIRT2 SLAIN1 SLC44A1 SLC5A11 SPOCK3 ST18 STMN4 SYNJ2 TBC1D12 TF TMEM144 TMEM151A TMEM88B TNFRSF21 TP53INP2 TRAK2 TUBA1A UGT8 ZNF488 Minor Salivary Gland Male 50-59 Up AGFG2 AGR2 ALDH1A3 ALX1 AMTN ANKRD36C APCDD1L AQP5 ASCL3 ATP6V1B1 AZGP1 BIK BPIFB2 BPIFB6 C6ORF58 CCDC160 CCL28 CEP41 CHST9 CRACR2A CRACR2B CREB3L1 CRISP3 CXCL17 DEFB1 DNASE2B EHF ELF5 ENPP3 FAM3D FBN3 FDCSP FUT2 GALE GALNT3 GALNT4 GALNT6 GLYATL2 GOLM1 GPRC6A HTR3A JCHAIN KCNN4 KRT7 KRT76 LCN2 LHX8 LPO LRRC26 LTF LYZ MLPH MMP3 MMP7 MRGPRX3 MUC16 MUC19 MUC5B MUC7 NAALADL2 NKX2-6 ODAM OTX1 PAX3 PIGR PIP PLEKHS1 PLPP2 PROM1 PRR27 PRR4 RAD51B RNASE8 RUNX1 SCNN1A SH3BP4 SLC6A14 SLITRK6 SLPI SMR3B SOX9 SPDEF SPINK14 STATH SVOPL TCN1 TFCP2L1 TMED3 TMEM200C TMEM63A TNFRSF11A TNFSF15 TOX3 TRPV4 VGLL1 VTCN1 WFDC2 XBP1 ZG16B ZNF552 Brain - Cortex Male 50-59 Up ADGRA1 ADGRB1 ADGRB2 ANKRD24 ATCAY BHLHA9 BRINP2 BRSK1 C11ORF87 C2CD4C CABP1 CACNG3 CAMK1G CAMK2A CASKIN1 CBLN2 CCK CHD5 CHRM1 CIT CLEC2L COL26A1 CUX2 DAGLA DBNDD1 DGKZ DOC2A DPF1 EIF4E1B ELFN2 FAM163B FAM81A FBXO41 FXYD7 GABBR2 GALNT8 GRIN1 GRM2 HAPLN4 HECW1 HTR3B ITPKA KCNAB2 KCNH3 KCNIP3 KCNJ4 KCNS1 KCNS2 KCNV1 KIAA1549L KIF1A KIF5A LCN15 LINGO1 LRFN2 LRFN5 LRRC4 LYNX1 MAP1A MAST3 MCF2L2 MCHR2 MGAT5B MPPED1 NAGPA NCALD NLK NPM2 NRGN OLFM1 OPRD1 PACSIN1 PDXP PHF24 PI4KA PNMA3 PNMA6A PRKAR1B PTPRT R3HDM1 RAB3A RAB6B RAPGEF4 RIMS3 RNF208 RPH3A RTP1 SHC3 SLC6A17 SNPH SNX32 SOHLH1 SPRN STX1A SULT4A1 SYN1 TBR1 TESPA1 UNC5A VSTM2L Brain - Cerebellum Male 50-59 Up ABCG4 ACAP3 ADAM11 AKAIN1 ALS2 ARHGEF33 BARHL1 BARHL2 BRICD5 CACNA1A CAMKK2 CARMIL3 CBLN1 CBLN3 CCDC175 CDH15 CDH22 CELSR3 CKMT1B CLK4 CNPY1 CPLX4 DAB2IP DISP2 EN2 FAT2 FGF17 FGF3 GABRD GALNT9 GNG13 GRID2IP GRIN2C GRM4 IGLON5 KCNAB3 KCNC1 KCNK9 KLHL3 LCN8 LHX1 MCF2L MDGA1 MEGF11 MMP24 MTCL1 MYT1 NBPF20 NEUROD2 OR1F1 OTX2 PAX6 PCLO PKD1 PLEKHD1 PPFIA4 PPIP5K1 PRR35 PRSS51 PVALB RAB37 RBFOX3 RGS11 RNF112 SBK1 SHF SHISA8 SKOR1 SLC1A6 SLC22A31 SLC35F4 SLC6A7 SLC8A2 SOGA1 SRGAP2 SRRM3 SRRM4 ST8SIA5 STRC STXBP5L TFAP2E TLE2 TLX3 TMC2 TMEM132E TMEM145 TMEM178A TMEM266 TRIM3 TRIM67 TRIM9 UNCX WSCD2 XKR7 ZFYVE28 ZIC2 ZIC3 ZIC4 ZIC5 ZP2 Whole Blood Male 40-49 Up ADAM8 ADGRG3 ALOX5 ALPL APBB1IP APOBR ARHGDIB ARRB2 BIN2 C19ORF38 C1ORF162 CD300C CD300LF CDA CEACAM4 CFP COTL1 CSF3R CST7 CXCR1 CYBA CYTH4 DOK3 EFHD2 EVI2B FCER1G FCGR2A FCN1 FERMT3 FGD3 FGR FKBP8 FPR1 FRAT2 FUT7 GMFG GMIP GPSM3 GRK6 GYPC HBA2 HCK HCLS1 HK3 IFITM2 ITGB2 JAML LAPTM5 LILRA1 LILRA2 LILRA5 LILRA6 LILRB2 LILRB3 LIMD2 LRRC25 LSP1 LST1 LYL1 MPP1 MSRB1 MYO1F NCF2 NCF4 NFE2 NLRP12 OSCAR PLBD1 PRAM1 PSTPIP1 R3HDM4 RAC2 RASGRP4 RGS19 RHOG RIN3 RPS6KA1 S1PR4 SELL SELPLG SH3BGRL3 SHKBP1 SIGLEC5 SIGLEC9 SIRPB1 SLC12A9 SLC25A37 SPI1 STXBP2 TBXAS1 TNFAIP8L2 TNFRSF10C TYROBP VASP VAV1 VNN2 VSIR WAS XPO6 ZDHHC18 Cells - Cultured Fibroblasts Male 40-49 Up ADAM12 ADAM9 ADAMTS2 ADAMTS6 ALDH1L2 ARSJ ASCC3 AZI2 BRIX1 C6ORF120 CALU CCBE1 CCDC80 CD109 CHML CITED2 CKAP4 CLEC11A COL12A1 COL1A1 COL1A2 COL5A2 COL6A3 CTHRC1 DCBLD2 DKK1 DSEL EDA2R EIF2AK4 FAP FBN1 FBN2 FGF5 FKBP10 FKBP14 FN1 FRMD6 FZD2 GCNT1 GPR176 GPX8 GREM1 HIF1A HMGA2 HOXC8 HS3ST3B1 IGF2BP2 IGF2BP3 IKBIP KCNK2 KDELR3 LAMC1 LOX LOXL2 LRP12 MME MYOF NECTIN3 NID2 NT5E OLFML3 OPN3 OR1J4 OR1Q1 PAPPA PCDH18 PCDHGA11 PCDHGA12 PCDHGB4 PCOLCE PLOD2 PRR16 PTX3 RAI14 RCN1 RCN3 RECK SEC22B SNAI2 SNAPC1 SRGAP1 STC2 STEAP1 STEAP1B TGFBI THBS1 TMEM119 TNFRSF10D TNPO1 TRAM1 TRAM2 TTPAL TWIST1 TWIST2 ULBP1 VGLL3 WNT5A XPOT YIPF5 ZNF281 Brain - Hippocampus Male 40-49 Up ABHD17B ADARB2 AMER2 ANKS1B ANO4 APC ASPA B3GAT1 BHLHE22 C1QL2 CABP7 CACNG8 CAMK2A CCP110 CERCAM CNDP1 CNIH2 CNP CNTN2 CPLX2 DEAF1 DGKZ DLG2 DLGAP3 DOK6 EPHA5 ERMN EVI2A FEZF2 FGF1 FGF13 FIBCD1 FKBP1B GPR37 GPR62 GPRC5B GRIA1 HHIP HIPK2 HRK HTR1A IDS JPH3 KCNH3 KCNH8 KCNK10 KCNK4 KCNN1 KLHL32 LACC1 LY6H MAS1 MFRP MKRN3 MOG MTURN MYRF NCS1 NEUROD6 NEUROG3 NKAIN2 NPTXR NSMF OLIG1 OLIG2 OMG OPALIN P2RX7 PAIP2B PCDH9 PEX5L PHACTR3 PIP4K2A PLPPR1 PLPPR4 PRKCG PRR18 PXK RAPGEF4 RTP5 SEZ6L SHANK1 SHTN1 SLAIN1 SLCO1A2 SPOCK3 ST6GALNAC5 STMN4 STUM SYTL5 TMEFF1 TMEM144 TMEM235 TMEM88B TMTC4 TNR TPPP TRIM2 TTYH2 ZNF488 Brain - Anterior Cingulate Cortex (BA24) Male 40-49 Up ACBD7 APC ASIC2 ATOH7 BRINP2 C1QL3 C2CD4C C2ORF80 CA11 CAMK2N1 CCK CDH9 CNTN5 COX6A1 CREG2 CSPG5 CTNNA2 CTNND2 DEAF1 DLG2 DLX1 DOK6 DPP10 DRD5 ELFN2 ENC1 ENHO EPHA5 ERC2 FAM171B FAM81A FEZF2 FREM3 GABRA2 GABRA3 GAD1 GAP43 GDA GPM6A GRIN3A GSG1L2 HPCAL4 HSD11B1L IDS KCNC2 KCNN1 KCTD16 LHX2 LRRC53 MAP2 MAPK8IP2 MEIS3 MPPED1 MT3 MYRIP NANOS3 NCAM2 NCAN NCS1 NPTXR NRCAM NRG3 NRSN1 NSMF NXPH2 OLFM1 OSTN PCDH11Y PGM2L1 PHF24 PLPPR5 PNMA2 PPP4R4 PTER RAB6B RAPGEF4 RASL10A RNF182 SCG3 SCN3B SERPINI1 SFXN5 SHANK1 SHC3 SLC25A18 SLC35F1 SLC39A12 SLC4A10 SLC6A1 SMIM10L2A STOX1 STUM SYN2 SYT16 SYT17 TFPT TMEM160 TNR TSPOAP1 WSB2 Brain - Caudate (Basal Ganglia) Male 40-49 Up ACBD7 AKAP5 ALDH7A1 AMBN ANKRD34B ANO3 AQP4 ARPP19 ARPP21 ATP2B1 BAALC CABLES1 CACNG4 CHAT CORT CPE CST3 CTXN1 CYP46A1 DACH1 DGKB DLX6 DRD1 ENHO ENTPD3 ETNPPL FAM171B FBXL16 FKBP1B GABRA2 GABRA4 GABRG1 GAD2 GNAL GNG7 GPC5 GPR139 GPR85 GPR88 GRM3 HHIPL1 HPCA HS3ST5 IFNA6 JAKMIP1 KCNH4 KCTD17 LGI1 LRRC10B LRRC7 LRRN1 LRTM2 MC4R MEGF10 METRN MLC1 MZT1 NDP NR2E1 NTSR2 ONECUT2 OPALIN OTOF PCP4 PCP4L1 PDE10A PDE1B PLCB1 PLPPR1 PLSCR5 PON2 POU3F4 PPP1R1B PPP3CA PSD2 PTPN5 RANBP3L RASD2 RESP18 RGS14 RGS20 RGS9 RIC8B RLBP1 SCN4B SIX3 SLC1A2 SLC24A2 SLC25A23 SLC35D3 SP9 SPEF1 ST8SIA3 STRIP2 SYNDIG1L TAC1 TMEFF1 TMEM158 TTYH1 VAX1 Brain - Nucleus Accumbens (Basal Ganglia) Male 40-49 Up AKAP5 AMER2 ANKRD63 ANKS1B ARPP21 C1QTNF4 C4ORF50 CACNA1E CACNG4 CAMKV CHAT CNMD COCH CSMD3 CTXN1 DEFB112 DLL3 DLX6 DRD1 DRD3 DTNBP1 EFNB3 GABRA5 GABRG1 GAD2 GNAL GNG7 GPR101 GPR149 GPR27 GPR52 GPR6 GRM3 HS6ST2 HTR1D HTR2C HTR6 IDNK IMPG1 JAKMIP1 KCNA4 KCNH4 KCNIP1 KCTD4 KIRREL3 LAMP5 LHFPL3 LHX8 LIX1 LRRC7 LRRTM1 LYPD1 MEGF10 MEPE MINDY4B NCDN NECAB2 NKAIN4 NPAS3 NTRK1 NTSR2 OMG OPALIN OPRK1 OTOF P2RY12 PCDH11X PCP4L1 PDE6B PDYN PHACTR1 PLPPR1 PLPPR3 POU3F4 PPP2R2B PRR7 PTPN5 RAB40B RGS20 RGS8 RPRML SHISA7 SIX3 SLC18A3 SLC32A1 SLC9A7 SLCO1A2 SORCS3 SOWAHA SOX11 SP9 SPOCK3 SV2C SYNPR THRA TMEFF2 TTYH1 VAX1 WNT1 WNT10B Brain - Putamen (Basal Ganglia) Male 40-49 Up ACBD7 ADORA2A ALDH7A1 AMBN AMER2 ANO3 ARPP19 ARPP21 ASIC1 ASRGL1 ATP1B2 BAALC BTBD17 CABLES1 CACNG4 CERCAM CHAT CNDP1 COCH CORT CST3 CYP46A1 DGKB DLX6 DRD1 DRD2 ENHO ENTPD3 ETNPPL EYA1 GABRA2 GBX2 GNAL GNG7 GPC5 GPR37L1 GPR6 GPR88 GPRC5B GRM3 HDAC11 HIPK2 HMX1 HPCA HRH3 HS3ST5 IFNA6 KCNH4 KCNH8 KCNJ10 KCNJ14 KCNK10 KCTD17 LPAR1 LRRC10B LRTM2 MEGF10 METRN MLC1 MT3 NR2E1 NTSR2 OLFM2 OLIG1 OLIG2 OMG OPALIN PCP4 PCP4L1 PDE10A PDE1B PHLPP1 PLPPR1 PPP1R1B PPP2R2B PRR18 PSD2 PTPN5 QDPR RANBP3L RASD2 RGS14 RGS20 RGS9 RLBP1 SCN4B SEC14L5 SFXN5 SLC18A3 SLC1A2 SLC1A3 SLC24A2 SLC6A12 SPOCK3 SYNDIG1L TMEM229A TMEM235 TRIL TSC22D4 TTYH1 Skin - Sun Exposed (Lower Leg) Male 40-49 Up AADACL2 ABCA12 ACER1 ADGRF2 ADGRF4 AHNAK2 ALOX12B ALOXE3 ANKRD35 ASPRV1 ATP6V1C2 BPIFC C1ORF68 C2CD4D C3ORF52 CALML5 CASP14 CDHR1 CDSN CLDN1 CLEC2A CTNNBIP1 CYP4F22 DAPL1 DEGS1 DLX3 DLX5 DMKN DSC1 DSC3 DSG1 DSP EFNA3 EPHB3 ETV3 EXPH5 FLG FLG2 FOXN1 GAN GATA3 GJB4 GSDMA HELT HS3ST6 IDE IFFO2 IGFL3 IL1RL2 IL36B IL36RN IL37 KCNK7 KLC3 KLK7 KLRF2 KPRP KRT1 KRT10 KRT2 KRT80 LAMB4 LCE2B LCE4A LIPM LY6G6C LYPD5 MYCL NIPAL4 PERP PKP1 PLA2G4E PLA2G4F PNPLA1 POF1B POU2F3 PSAPL1 RDH12 RNF39 RORA SBSN SDR42E1 SDR9C7 SERPINA12 SERPINB7 SLC46A2 SPRR2G SRY TGM5 THEM5 TINCR TMEM45A TMEM86A TMPRSS13 TRIM35 TRPM1 TUFT1 UNC93A WFDC5 XKRX Adipose - Subcutaneous Male 40-49 Up ACER2 ACKR2 ACO1 ACVR1C ADAMTS5 ADCY4 ADGRL4 ADH1B ADIPOQ ADRA2A AFAP1L1 AGTR1 AIFM2 ANGPT4 ANGPTL4 APOL3 APOLD1 AQP7 ARHGAP20 ARHGEF15 AVPR2 BMP6 BNIP3L C19ORF12 CD248 CD300LG CD36 CFD CIDEC CILP CLEC3B CNOT8 CPM DOCK11 EBF1 EBF3 ELMOD3 FABP4 FAM124B FGD5 FZD4 GABRE GALNT15 GFRAL GGT5 GHR GPD1 GPR146 GSN HEBP2 HTR1F INHBB ITGB1BP1 ITIH5 KCTD12 LEP LHX6 LIPE LRRC8C LVRN MAN1A1 MEOX1 MMP3 MMRN2 MOCS1 NEDD9 NMT2 PDE3B PECAM1 PHLDB1 PLIN1 PLIN4 PLXNA4 PNPLA2 PPARG RAI2 RAMP2 RNF125 S1PR1 SASH1 SEMA3G SERPINF1 SIK2 SLC19A3 SMIM3 SRPX2 STAT5A STEAP4 SYNE3 TACR1 TGFBR3 TIMP3 TIMP4 TMEM132C TNMD UVRAG VKORC1L1 VWF ZBED3 ZNF366 Nerve - Tibial Male 40-49 Up AATK ABCA10 ABCA8 AFAP1L2 ANGPTL7 APOD ARHGAP19 ARHGAP39 ARHGEF10 BIRC7 BMP8B CADM4 CASKIN2 CDH19 CDO1 CLCN2 CLDN19 CLDN20 CNTF COL28A1 DCLK3 DHH DRP2 EBF2 EGFL8 EGR2 EHBP1 EMILIN3 EXTL1 FGF4 FGFBP2 FIGN FMNL3 FOXD1 FOXD2 FOXD3 FRMD8 GAS2L3 GJC3 GLI1 GNRH1 HSPA12A IGFBP6 IL17B IL9 INF2 ITGA6 ITGB8 KANK4 KCNK12 KIF19 LCTL LGI4 MAPK8IP1 MATN3 MIA MICALL2 MPZ NCMAP NEK1 NGFR OR6B2 OR6B3 OTUD7B PAPLN PLEKHA4 PMP22 PRICKLE1 PRIMA1 PRRG3 PRX PTGFR PTPDC1 PTPRU RTKN SBSPON SCN7A SECISBP2L SEMA3B SEMA4C SEMA5A SFRP5 SHC4 SHH SLC25A48 SLC2A1 SLC6A20 SMCO3 SORCS1 SPTBN5 ST6GALNAC2 THSD7A TLDC2 TMEM215 TMPRSS5 USP53 VIT VWA1 WNT6 ZDHHC8 Artery - Tibial Male 40-49 Up ACAN ACTA2 ACTN4 ADARB1 ADIRF ADRA2C AMIGO2 ARHGEF17 ARHGEF39 ATL3 AVPR1A C11ORF96 C12ORF75 CDH6 CHSY3 CLIC4 CNTN4 COL14A1 COL18A1 COMP CPED1 CRLF1 CRTAC1 CRTC3 CSPG4 CSRP2 DACT3 DSTN EFHD1 ELL2 ENAH FBLIM1 FHL5 FOXC1 FOXC2 FOXL1 FRY HEY2 HTR1B ID2 IGFBP7 ITGA5 JAG1 JAK2 KCNA5 KCNAB1 KCTD10 KLHL26 LMOD1 LPP MAP7D3 MBNL1 MCAM MSRB3 MUSTN1 MYBL1 MYO1D NKD1 NOTCH3 NTF3 NTRK3 P2RX1 PDK3 PLEKHG3 PLS3 PPP1R14A PRELP PRKG1 RASL12 RASSF3 RCAN2 RERGL RHOB RNF180 ROCK1 ROR1 RSU1 SDK1 SH3BGRL SH3RF3 SMAD7 SMIM10 SMURF1 SORBS2 SPOPL TAGLN TASP1 TBX18 TBXA2R TGM2 TLN1 TMEM181 TMEM47 TNC TNS1 TRABD2B USP35 WDR1 WTIP ZFHX3 Breast - Mammary Tissue Male 40-49 Up ADAMTS3 ADCY4 ADGRL4 ADRB2 ALX4 ANGPT4 ANKRD30A APOL4 AQP7 ARHGAP40 ARHGEF15 AVPR2 BTNL9 CD300LG CD36 CIDEC CLDN5 CYYR1 FABP4 FAM124B FGF10 GLRA3 GPIHBP1 GPR146 GSC HCAR1 HEBP2 HSPA12B IGF1 INHBB LIPE MDFI MEOX1 MMRN2 NLRP8 NOSTRIN NOTCH4 NPY2R PEMT PI15 PLIN1 PNPLA2 PPARG PROKR1 PTHLH RAMP2 RBP7 S1PR1 SCGB1D2 SCGB2A2 SELP SEMA3G SLC19A3 SOX17 SPAAR TACR1 TFAP2B TIMP4 TMEM132C TMEM26 TNN TRPS1 USHBP1 VTCN1 ZNF366 Muscle - Skeletal Male 40-49 Up ADPRHL1 ADSL ALDOA ANKRD23 ANKRD39 ART1 ASB12 ASB2 ASB8 BEST3 BIN1 BTBD1 C19ORF47 CACNA1S CACNB1 CACNG1 CACNG6 CAND2 CHRNB1 CHRND CKM CMYA5 COQ8A CYB5R1 DCAF6 DUSP13 EEF1A2 ENO3 EYA4 FEM1A FHL3 FXR1 GMPR IP6K3 JPH1 JSRP1 KCNA7 KCNJ11 KLHL40 KLHL41 LBX1 MACROD1 MAFA MAPK12 MRLN MYBPC1 MYBPC2 MYO18A MYO18B MYOZ1 MYPN NEB NFE2L1 NRAP OBSCN OPTN OSBPL11 P2RX6 PDE4DIP PDLIM3 PFKM PGM1 PGPEP1L PHKA1 PHKG1 PHTF2 POPDC3 PPP1R27 PRKAG3 PRKCQ PROB1 PYGM RAD23A RAPSN RNF123 RPUSD4 RTN2 RYR1 SCN4A SMTNL2 SPTB STAC3 SYPL2 TEAD4 TMEM233 TMEM38A TMOD4 TNNC2 TNNI2 TNNT1 TNNT3 TRDN TRIM54 TRIM72 TTN UBR3 UCP3 USP13 UTP11 YBX3 Skin - Not Sun Exposed (Suprapubic) Male 40-49 Up AADACL2 AADACL3 ACAD9 ACER1 AHNAK2 ANXA8L1 ARHGEF19 AWAT1 AWAT2 BPIFC C11ORF80 CAPNS2 CARD18 CCL27 CD207 CDHR1 CDX4 CLDN1 COL17A1 COL7A1 CPA4 CST6 CYP4F22 DEGS1 DGAT2L6 DMKN DNASE1L2 DSC3 EFNA3 ELOVL3 FOXN1 GAL3ST4 GAN GATA3 GJB3 GJB4 GJB5 HOXC13 HR HS3ST6 IFFO2 IGFL2 IL20RA IL20RB IRF6 IRX3 IRX4 KCNK7 KLC3 KRT1 KRT14 KRT17 KRT77 KRT79 KRT80 KRTDAP LAMB4 LGALS7B LIPK LRIT2 LY6G6C LYPD6B MLANA NIPAL4 NKPD1 OLIG3 PARD6G PERP PGLYRP4 PKP1 PLA2G2F PLA2G4F PM20D1 PNLIPRP3 PNPLA5 POU2F3 PPP1R13L PPP1R14C PSAPL1 SDC1 SDR42E1 SEC14L6 SERPINB5 SLC39A2 SP6 SPINT3 SRD5A1 TFAP2A TFAP2C TGM5 TINCR TMEM254 TMEM45A TNFRSF18 TNFRSF19 TNS4 TP63 VANGL2 WFDC5 ZNF273 Brain - Cerebellum Male 40-49 Up ADAM11 ADAM22 AKAIN1 ALS2 ARHGEF33 BARHL2 BSPH1 CA8 CACNA1A CACNA1G CALN1 CAMK4 CAMKK2 CARMIL3 CBLN1 CBLN3 CCDC175 CECR2 CELSR3 CHD7 CKMT1B CLK4 CLVS2 CNPY1 COL27A1 CPLX4 DISP2 EN2 EPB41 FAT2 FGF17 FUT9 GLCE GNG13 GPR137C GRID2 GRID2IP GRIK2 GRIN2C GRM1 GRM4 IGLON5 KCNC1 KCNK9 KLHL3 LHX1 MDGA1 MEGF11 MMP24 MTCL1 MYT1 NBPF20 OTX2 PAX6 PCLO PKD1 PLEKHD1 PPFIA4 PPIP5K1 PPP1R17 PRR35 PRSS51 PTPRR PVALB RNF112 SBK1 SCN2A SHF SKOR1 SLC1A6 SLC22A31 SLC35F4 SLC6A7 SOGA1 SRGAP2 SRRM3 SRRM4 ST8SIA5 STRC STXBP5L SYT2 TENM1 TFAP2E TMC2 TMEM145 TMEM178A TMEM266 TRIM67 TRIM9 TRPM3 UNC80 WSCD2 XKR7 ZFYVE28 ZIC2 ZIC3 ZIC4 ZIC5 ZNF382 ZP2 Brain - Cortex Male 40-49 Up ADCY1 ADGRA1 ADGRB1 ADGRB2 AGBL4 ANKRD24 ATCAY ATRNL1 B3GAT1 BHLHA9 BRINP2 BRSK1 C11ORF87 C2CD4C CABP1 CACNG3 CAMK2A CAMK2N1 CBLN2 CCK COL26A1 CREG2 CTNNA2 CUX2 DAGLA DBNDD1 DPF1 EIF4E1B ELFN2 ENC1 FAM163B FBXO41 FREM3 FRMPD4 FXYD7 GABBR2 GALNT8 GPR26 GRIN1 GRIN2A HAPLN4 HECW1 HS3ST4 HTR1A HTR3B ITPKA KCNH3 KCNH5 KCNJ4 KCNN1 KCNS1 KCNS2 KCNV1 KCTD16 KIAA1549L KIF5A LCN15 LHX2 LINGO1 LRFN2 LRFN5 LRRTM4 LYNX1 MAP1A MAST3 MCF2L2 MCHR2 MGAT5B MPPED1 NCALD NLK NRGN OLFM1 OPRD1 OR14I1 PACSIN1 PDXP PHF24 PI4KA PRKAR1B R3HDM1 RAB6B RAPGEF4 RASGRF2 RGS4 RIMS3 RNF208 RPH3A RTP1 SHC3 SLC17A7 SLITRK1 SOHLH1 SPRN STX1A SVOP SYN1 TBR1 TESPA1 TMEM132D Pituitary Male 40-49 Up ANKRD33 ARFGAP1 ARHGAP36 ASCL1 ASIC4 AVPR1B BAIAP3 C14ORF39 C17ORF107 C21ORF58 C2CD4A C2ORF15 CDRT4 CFAP47 CFC1 CGA CGB3 CHGB CHRNE CHST8 CNGA3 COL22A1 COL9A2 COQ8B CSH1 CSH2 CSHL1 DGKK DMRTA2 FAM163A FAM24B FBXO16 FFAR4 FOXO6 GAGE10 GAL GALR1 GCK GH1 GHRHR GHSR GJB7 GJD2 GNAS GNB3 GPR148 HTATSF1 IGSF1 INSM1 KSR2 LHB LHX3 MYO15A NEUROD4 NNAT OR13C2 OTOS PCDHB1 PCSK1N PHF21B PLD3 PLET1 POMC POU1F1 PRL PRLHR PROP1 PTPRN RAX REC8 RIIAD1 RIMBP2 RNF224 RPH3AL RTBDN SCG5 SIX3 SIX6 STK33 SYNGAP1 TAC4 TBX19 TCP11X1 TGFBR3L TMEM179 TMEM244 TMEM61 TMEM63C TRHR TRPC3 TRPC7 UBTFL1 UGT2A1 UGT2A2 VWA7 VWDE ZFR2 ZNF10 ZNF667 ZP1 Ovary Female 60-69 Up ACSM3 ADAMTS16 ADRB3 AMHR2 ANGPTL5 ARX ASIP BAMBI BST2 C21ORF62 CASP9 CCNB1IP1 CD22 CDH23 CDK15 CHST7 CLCN5 CLSTN2 COL16A1 CPZ CRYGD ECEL1 EML5 FAM153B FFAR1 FOXL2 FOXL2NB GALNT10 GATA4 GATA6 GLI2 GREB1 GSTM2 GSTM5 HNRNPA1 HS3ST1 HSD17B14 IGDCC4 IGFBP5 IGSF10 INHA KCNMB2 KLHDC8A LAG3 LHX9 LPAR4 LRRC17 MCC MDK METAP1D MEX3A MMP21 NBL1 NECAB3 NFATC4 NINL NR4A2 NRK NYNRIN OBSL1 OR8S1 PAGR1 PEG3 PHF6 PROK1 RASL11B RBP1 ROBO3 RPL18 RPL24 RPL35A RPL5 RPS27 RPS8 SIGLEC11 SIGLEC16 SIMC1 SLC4A3 SLC8B1 SNCAIP ST13 SULT1C4 SYTL4 TCEAL9 TDGF1 TDGF1P3 TENM4 TMEM221 TMEM98 TRABD2A TSHZ3 TTC8 UBXN8 VLDLR VWCE WFIKKN2 WIPF3 ZMYM3 ZNF556 ZNF66 Nerve - Tibial Female 60-69 Up AATK ABCA10 ABCA8 AFAP1L2 AHR ANGPTL7 APOD ARHGAP19 ARHGAP39 ARHGEF10 BEST1 BIRC7 BMP8B CDH19 CHL1 CLDN19 CNTF COL28A1 CYB5R2 DCLK3 DHH DRP2 EBF2 EGFL8 EGR2 EHBP1 EMILIN3 ENTPD2 EPB41L2 EXTL1 FIGN FMNL3 FOXD1 FOXD2 FOXD3 GAS2L3 GFRA3 GJC3 GLI1 GNRH1 HSPA12A IGFBP6 IL17B IL1RAPL1 IL34 INF2 INSC ITGA6 ITGB4 ITGB8 KANK4 KCNK12 KIF19 LCTL LGI4 LRRC8B MIA MICALL2 MPZ NCMAP NEK1 NGFR NRBP2 OR6B2 OR6B3 OTUD7B PAPLN PLAG1 PLEKHA4 PMP22 PRIMA1 PRRG3 PRX PTPDC1 RHBDF1 SBSPON SCN7A SECISBP2L SEMA3B SEMA4C SFRP5 SHC4 SHH SLC25A48 SLC2A1 SLITRK5 SMCO3 SORCS1 SPTBN5 ST6GALNAC2 STARD13 SYT10 THSD7A TLDC2 TMPRSS5 USP53 VIT VWA1 WNT6 ZDHHC8 Brain - Frontal Cortex (BA9) Male 60-69 Up ADGRA1 AK5 ANKRD24 ATRNL1 BHLHA9 BRINP2 C11ORF87 C3ORF80 CABP1 CAMK2A CAMK2N1 CBLN2 CCK CHN1 CLEC2L CNTNAP2 COL26A1 CREG2 CTNNA2 CTXN3 DLGAP1 DPP10 EIF4E1B ELAVL4 ENC1 EPHX4 FAM163B FAM81A FXYD7 GABBR2 GABRA1 GABRG2 GALNT8 GAP43 GLRB GRIA3 GRIN2A HAPLN4 HCN1 HECW1 HTR1E HTR2A HTR3B KCNC2 KCNH5 KCNJ4 KCNS1 KCNS2 KCNV1 KCTD16 KIAA1549L KIF5A LINGO1 LMO4 LRFN2 LRFN5 MAPK10 MCF2L2 MCHR2 MGAT5B MPPED1 NAP1L2 NCALD NECAB1 NEFL NEFM NELL1 NELL2 NLK NPBWR2 NRG3 NRGN OLFM1 OLFM3 OPRD1 OR14I1 PNMA6A POU6F2 PRKAR1B PTPRT RAB3A RAB6B RGS4 RIMS3 RORB RPH3A SCG3 SCN1A SERPINI1 SLITRK1 SNCB SULT4A1 SYT1 TBR1 TESPA1 TMEM132D VSNL1 VSTM2A YWHAH ZNF365 Brain - Cerebellar Hemisphere Male 60-69 Up ADAM22 AKAIN1 ALS2 AMER3 BARHL1 BARHL2 CA10 CACNA1A CADPS2 CAMK4 CAMKK2 CBLN1 CBLN3 CCDC177 CDH22 CHN2 CKMT1B CNPY1 CRTAM DIRAS2 DISP2 EN2 ETV1 FAM131C FGF3 FSTL5 GABRA6 GABRD GPR137C GPR158 GPR83 GRIA4 GRIK2 GRIN2C GRM1 GRM4 IGLON5 KCNA1 KCNC1 KCND2 KCNJ3 KCNK9 LHX1 MAB21L1 MDGA1 MEGF11 MKRN2OS MMP24 MTCL1 MYT1 NEUROD1 NEUROD2 NKX6-3 NPTX1 NREP NRXN3 PAK5 PAX6 PCDHA8 PCDHGC4 PKIB PLK5 POLB PPFIA4 PRR35 PTH2 RAB26 RAB37 RBFOX3 RELN RIMS1 RIT2 SHF SHISA8 SLC35F4 SLC8A2 SOGA1 SRRM3 SRRM4 SYT2 SYT4 TFAP2E TIAM1 TLX3 TMEM145 TMEM178A TMEM266 TUBA8 UNCX VAX2 VSX1 VWC2 XKR7 ZBTB18 ZIC1 ZIC2 ZIC3 ZIC4 ZIC5 ZNF521 Brain - Caudate (Basal Ganglia) Male 60-69 Up ACBD7 ADCYAP1R1 ADORA2A ANKRD34B ANO3 AQP4 ARPP19 ARPP21 BCAN C1QTNF4 CABLES1 CACNG4 CDH20 CNMD CORT CPE CTXN1 CYP46A1 DACT2 DGKB DLX6 DRD1 ENHO ENTPD3 ETNPPL FAM171A1 FBXL16 FBXO2 FKBP1B GABRA2 GABRA4 GABRG1 GAD2 GNG7 GPC5 GPR143 GPR37L1 GPR6 GPR88 GRM3 HEPACAM HHIPL1 HPCA HS3ST5 HTR1D HTR6 IL17D IQCA1 JAKMIP1 KCNH4 KCNK18 KCTD17 KHDC1L LRRC10B LRTM2 MAPK4 METRN MINDY4B MLC1 NCDN NDP NECAB2 NGEF NR2E1 NTSR2 NWD1 ONECUT2 OTOF PCP4 PCP4L1 PDE10A PDE1B POU3F2 POU3F4 PPP1R1B PPP3CA PSD2 PTPN5 RASD2 RESP18 RGS14 RGS20 RGS9 RIC8B RLBP1 SCN4B SIX3 SLC1A2 SLC25A23 SLC35D3 SP9 SPEF1 STON2 STRIP2 SYNDIG1L TAC1 TMEM158 TRIL TTYH1 VAX1 Brain - Nucleus Accumbens (Basal Ganglia) Male 60-69 Up ACTR3B AKAP5 ANKRD34B ANKRD63 ARPP21 C1QTNF4 C4ORF50 CACNA1E CACNG4 CAMKV CNMD COCH CPNE5 CRYM CTXN1 CYP46A1 DACH2 DACT2 DLL3 DLX6 DRD1 DRD3 DTNBP1 EFNB3 GABRA4 GABRA5 GAD2 GNAL GNG7 GPC5 GPR101 GPR149 GPR27 GPR52 GPR6 HS6ST2 HSPBP1 HTR1D HTR2C HTR6 ICAM5 IDNK IMPG1 JAKMIP1 KCNA4 KCNH4 KCNIP1 KCNK4 KCTD4 KIRREL3 KLF16 LAMP5 LINGO3 LRRC7 LRRTM1 LYPD1 MINDY4B NAT16 NCDN NECAB2 NTSR2 OPRK1 OTOF PCDH11X PCP4 PCP4L1 PDYN PENK PIANP PLPPR1 PLPPR3 POU3F4 PPP1R1B PRKCG PRMT8 PRR7 PSD PTPN5 RAB40B RESP18 RGS20 RGS8 RPRML SEZ6 SH2D5 SHISA7 SIX3 SLC32A1 SLC9A7 SORCS3 SOWAHA SP9 SPEF1 SV2C SYNDIG1L SYNPR THRA TMEM158 WNT1 WNT10B Brain - Putamen (Basal Ganglia) Male 60-69 Up ADORA2A AMBN ANO3 ARPP19 ARPP21 ASPHD1 BAALC C1QTNF4 CACNG4 CERCAM CERS1 CHAT CNDP1 CORT CPLX1 CST3 CTXN1 CYP46A1 DACT2 DGKB DLX6 DRD1 DRD2 EFR3B ENHO ENTPD3 ETNPPL EYA1 FBXL16 FKBP1B GAD2 GBX2 GNAL GNG7 GPR6 GPR88 GPRC5B GRM3 HCN2 HDAC11 HPCA HRH3 HS3ST5 HSPBP1 HTR1D JAKMIP1 KCNF1 KCNH4 KCTD17 LGI3 LRRC10B LRTM2 MAPK4 MEGF10 METRN MLC1 MT3 NGEF NRGN OLIG2 ONECUT2 OPALIN OTOF PCP4 PDE10A PDE1B PENK PPP1R1B PPP3CA PRR18 PRR7 PSD2 PTPN5 QDPR RAB40B RASD2 RESP18 RGS14 RGS20 RGS9 RLBP1 RPRML SCN4B SIX3 SLC18A3 SLC1A2 SLC24A2 SLC25A23 SLC39A12 SLC6A12 SOWAHA SP9 SPEF1 ST8SIA3 SYNDIG1L TAC1 TMEM235 TSC22D4 TTYH1 YJEFN3 Brain - Hypothalamus Male 60-69 Up ACHE ADCYAP1 AIRE AVP B4GAT1 BSX CALB2 CALCR CALY CAMK2N2 CARTPT CENPVL3 CFC1 CNGB1 CRH CSMD3 CXXC4 DIRAS3 DLX1 DNER ECE2 ECEL1 ERAS FBLL1 FEZF1 FNDC9 FOXB1 GABRG3 GABRQ GHRH GLRA2 GNG8 GRIK1 GRIN2D GRM7 GSX1 HAP1 HCRT HCRTR2 HDC INPP5F INSM2 KISS1R LHX5 LUZP2 LY6H MAGEL2 MC3R MC4R NAP1L5 NGB NPSR1 NPVF OTP OXT PABPC1L2A PABPC1L2B PCDH11Y PCSK1 PIRT PLPP4 PNMA5 PRDM12 PRDM13 QRFPR RAB3C RND2 RPE65 RTL1 RTP5 SCG2 SCN9A SLC17A6 SLC6A11 SMIM10L2B SMIM17 SMIM18 SNCG SOX1 SOX11 SOX14 SOX3 SST SYNGR3 SYT6 TACR3 TMEM114 TMEM17 TMEM196 TMEM255A TMIE TRH TUBB3 UCHL1 VAT1L VGF VSTM5 VWC2L ZBTB8B ZCCHC12 Liver Male 60-69 Up A1BG A1CF ABCB4 ABCC6 ABCG5 ABCG8 ACOT12 AFM AGXT AHSG AKR1C4 ALDH8A1 AMBP AMDHD1 ANG ANGPTL3 APCS APOA1 APOA2 APOA5 APOC1 APOC2 APOC3 APOC4 APOM ASGR1 ASGR2 ATF5 C4BPB C8A C8B C8G CA5A CCL16 CFHR2 CLDN14 COLEC10 CPB2 CPN2 CYP2D6 CYP2D7 CYP2E1 CYP4A22 CYP4F2 CYP8B1 EXOC3L4 F11 F12 F2 F7 F9 GBP7 GCGR GCKR GLTPD2 GOLT1A HABP2 HAO1 HGFAC HPD HPN IGFALS INHBE ITIH1 KDM8 KNG1 LEAP2 LECT2 LIPC MASP2 MAT1A MST1 NAT2 NPC1L1 NR1I3 PAH PLGLB2 PROC RBP4 RDH16 SAA4 SERPINA10 SERPINF2 SLC13A5 SLC17A2 SLC22A1 SLC22A25 SLC22A7 SLC22A9 SLC25A47 SLC27A5 SLC28A1 SLC2A2 SMLR1 TFR2 TMPRSS6 TTR UPB1 UROC1 VTN Artery - Coronary Male 60-69 Up AEBP1 ANTXR1 ARL4AP5 ART4 ASPN ATP10A BGN CCDC3 CFH CMKLR1 COL21A1 COL4A4 CPXM2 CRIP1 ECM2 EFEMP1 FBLIM1 FMOD FOXC2 FOXS1 FRK HAPLN1 HAUS7 HEYL ID4 IGFBP2 IGFBP7 ITGA10 ITGA8 IZUMO1R JAG1 KALRN KCNA5 KCNT2 LGR6 LRRC17 LTBP1 LTBP2 MAP3K7CL MEGF6 MFGE8 MGP MMP23B MSC MTHFD1L MYO1D NDUFA4L2 NTF3 NTRK3 OGN OMD P4HA3 PDGFA PLA2G5 PLAC9 PPP1R14A PRKG1 PTGIS SCARF2 ST6GAL2 SUGCT SULF1 TBX18 TBX2 TGM2 THBS2 TIMP1 TNFRSF11B VCAN Liver Male 50-59 Up A1BG A1CF ABCC6 ABCG5 ABCG8 AFM AGXT AHSG ALB ALDH8A1 AMBP AMDHD1 ANG ANGPTL3 APCS APOA1 APOA2 APOB APOC1 APOC2 APOC3 APOC4 APOF APOH ASGR1 ASGR2 C4BPB C5 C8A C8B C8G CA5A CFB CFHR1 CFHR2 CFHR3 CFHR4 COLEC10 CPB2 CPN2 CYP2D6 CYP2E1 CYP4F2 CYP8B1 EXOC3L4 F11 F12 F2 F7 F9 FTCD GCGR GCKR HAO1 HGFAC HP HPD HPN HPX ITIH1 ITIH3 ITIH4 KLKB1 KNG1 LEAP2 LPA MASP2 MAT1A MST1 NPC1L1 NR1I3 ORM2 PAH PLG PLGLB2 PON1 PROC PROZ RBP4 SERPINA10 SERPINA11 SERPINA6 SERPINC1 SERPIND1 SERPINF2 SLC13A5 SLC17A2 SLC22A1 SLC22A7 SLC22A9 SLC25A47 SLC27A5 SLC38A4 SMLR1 TFR2 TMPRSS6 TTPA UPB1 UROC1 VTN Brain - Cerebellar Hemisphere Male 50-59 Up ADAM22 AKAIN1 ALS2 ATP6V1G2 BARHL1 BARHL2 BRICD5 CA10 CACNA1A CADPS2 CALN1 CAMK4 CAMKK2 CBLN1 CBLN3 CCDC175 CCDC177 CHD7 CHN2 CLVS2 CNPY1 CNTN6 CPLX4 CRTAM DIRAS2 DISP2 EN2 ETV1 FGF3 FSTL5 GABRA6 GABRD GLCE GPR137C GPR158 GRIK2 GRIN2C GRM1 GRM4 KCNA1 KCNC1 KCND2 KCNJ3 KCNK1 KCNK9 LHX1 MAB21L1 MEGF11 MTCL1 MYT1 NEUROD1 NEUROD2 NPTX1 NREP NRXN3 OTX2 PAK5 PAX6 PCDHGC4 PKIB POLB PPFIA4 PRR35 RAB37 RAB3IP RELN RIMS1 RIT2 RNF112 SCN2A SH3GL2 SHF SHISA8 SLC35F4 SLC8A2 SOGA1 SPHKAP SRGAP2 SRGAP2B SRRM3 STXBP5L SYT2 SYT4 TIAM1 TLX3 TMEM178A TMEM266 TRIM67 TUBA8 UNCX VAX2 VSX1 VWC2 ZBTB18 ZIC1 ZIC2 ZIC4 ZIC5 ZNF521 ZP2 Brain - Substantia Nigra Male 50-59 Up ADARB2 ANKRD40 B3GAT2 BCAS1 C18ORF32 C1ORF122 CADPS CARNS1 CCDC160 CHRM5 CHRNB3 CLDND1 CLEC19A CNTNAP4 COL9A2 CTNNA3 CTXN3 DBNDD2 DBX2 DNER ERMN FEZ1 FGF1 FOXB1 GFAP GLRA1 GPR26 HCRTR2 HIPK2 KCNE5 KCNG4 KCNJ6 KIF6 KLHL1 LACC1 LHPP LPAR1 LRRC55 LUZP2 MBP MOBP MRGPRE MTURN NEFH NEFL NEFM NIPA1 NKX6-2 NTSR2 OC90 OLIG1 OLIG2 OTOR PAAF1 PAIP2B PAQR6 PHYHIPL PIP4K2A PIRT PKP4 PLCXD2 PLEKHB1 PLPP4 PMP2 POU3F2 POU4F2 PRR18 QDPR RET RND2 RNF141 ROM1 RPE65 S100B SCD5 SH3GL3 SHISA6 SHTN1 SLC10A4 SLC15A5 SLC17A6 SLC18A2 SLC5A11 SLC6A11 SLC6A3 SLCO1A2 SPOCK3 SPX ST8SIA2 TH TMEM229A TMEM255A TMEM88B TNR TP53INP2 TRIL TRIM41 TSC22D4 TUB VAMP1 Brain - Anterior Cingulate Cortex (BA24) Male 50-59 Up ADGRA1 ADGRB1 APC ARHGDIG ASIC2 BRSK1 BTBD2 C1QL3 C2CD4C CA11 CABP1 CAMK2A CAMK2N1 CASKIN1 CCK CEND1 CLEC2L CREG2 CSPG5 CTNNA2 CTNND2 DEAF1 DGKZ DLX1 DOK6 DPF1 DRD5 EIF4E1B ELFN2 ENC1 FAM163B FAM81A FBXO41 FEZF2 FXYD7 GABRA3 GALNT8 GAP43 GRIN3A HSD11B1L IDS JPH3 KCNAB2 KCNC2 KCNN1 KIF5A LHX2 LIMK1 LINGO1 LMO4 LRFN2 MAP1A MAP2 MAP3K10 MAPK8IP2 MCF2L2 MEIS3 MPPED1 NANOS3 NCAN NCS1 NPM2 NPTXR NRG3 NSMF OLFM1 OSTN PACSIN1 PALM PHF24 PNMA6A PRKAR1B PTER RAB6B RAPGEF4 RNF182 RNF208 RUNDC3A SERPINI1 SFXN5 SHANK1 SHC3 SLC17A7 SLC39A12 SMIM10L2A SMIM10L2B SNCB SNPH SOHLH1 STUM STX1A SULT4A1 SYN1 SYN2 TAGLN3 TBR1 TFPT TSPOAP1 TTC9B WSB2 Brain - Hippocampus Male 60-69 Up ADAP1 ADARB2 AMER2 APC B3GAT1 B3GAT2 BCAN BHLHE22 C1QL2 C1QTNF9B CABP7 CACNG8 CAMK2A CCDC85B CCP110 CERCAM CERS1 CNDP1 CNIH2 CNP CNTN2 CPNE4 CPNE6 DGKZ EPHA5 FEZF2 FGF1 FGF13 FIBCD1 GPR37 GPR62 GPRC5B GRIA1 HHIP HIPK2 HMX1 HRK ICAM5 JPH3 KCNG2 KCNH8 KCNJ6 KCNK4 KCNMB2 KCNMB4 KCNN1 KIAA0930 KIF6 KLHL2 KLHL32 LHFPL3 LY6H MAP4K4 MAS1 MKRN3 MMP17 MTURN MYRF NCS1 NEUROD6 NEUROG3 NKX6-2 NPTXR NRIP3 NSMF OLIG1 OLIG2 OMG OPALIN PAIP2B PCDH15 PCDH20 PDE6B PHACTR3 PIP4K2A PLPPR1 POU3F3 PPM1E PRKCG PRR18 PSRC1 QDPR RAPGEF4 RTP5 SCN3B SHISA6 SHTN1 SLAIN1 SLC17A7 SLC24A3 SLCO1A2 SOX8 SPOCK3 ST6GALNAC5 TMEM151A TMEM235 TMEM88B TNR TRIM2 TTYH2 Cells - EBV-transformed Lymphocytes Female 20-29 Up AICDA ANGPTL6 APOBEC3H BATF BHLHE22 BLNK BTLA C17ORF99 CCL17 CCL22 CCR7 CCR8 CD40 CD48 CD70 CD79A CD80 CENPM CLEC17A CLEC2D DUSP2 DUSP22 EAF2 EBI3 EED FAM72B FAM72C FAM72D FCER2 FSBP GCSAM GPR174 GSX2 HLA-DOA HLA-DPA1 HLA-DQA1 HLA-DQB1 HLA-DRA IFIH1 IFNA13 IKZF2 IL21R IRF4 IRF5 IRF8 LTA LY75 LY86 MACROD2 MCM2 MTFP1 MYBL2 NEK6 NEUROG2 NFKBIE OR2G6 OR2T2 OR2T29 OR2T3 OR2T34 OR2T5 P2RY10 PAX5 PIK3R6 PIM2 PMAIP1 PNOC POU2AF1 RAD54B RGS10 SH3KBP1 SIT1 SKAP1 SLAMF1 SLAMF6 SLAMF7 SPIB SPN STAP1 TCL1A TIFA TLR10 TMEM156 TMSB15B TNF TNFRSF13B TNFRSF13C TNFRSF17 TNFRSF8 TNFSF9 TRAF1 TSPAN33 USP17L15 VASH2 WDFY4 WNT10A ZC3H12D ZCCHC7 ZNF318 ZNF695 Whole Blood Female 20-29 Up ABTB1 ADAM8 ADGRE2 AGTRAP ALOX5 ALPL APOBEC3A AQP9 ARHGDIB ARL11 ARRB2 BIN2 C16ORF54 CD1B CD1E CEACAM4 CKLF CLEC4E CSF2RB CSF3R CXCR2 CYTH4 DNTT DOK3 DPEP2 EVI2B FCGR2A FCGR3B FGD3 FLOT2 FPR1 FRAT1 FRAT2 FUT7 GCA GLT1D1 GMFG GMIP GPR141 GPSM3 HCK HLA-C HRH2 ICAM3 IFITM2 IGSF6 IL10RB IL17RA IL18RAP IMPDH1 JAK3 LILRA2 LILRA5 LIMD2 LPAR2 MMP25 MSRB1 MXD3 MYD88 MYO1F NCF2 NCF4 NFAM1 NFE2 NLRC4 NLRP12 OLAH P2RY13 PLXNC1 PTAFR PTCRA PYGL R3HDM4 RAG1 RASGRP4 REM2 RGS19 S1PR4 SELL SELPLG SHKBP1 SIGLEC14 SIGLEC5 SIRPB1 SIRPB2 SLC22A4 SMAP2 SORL1 SPI1 TLR5 TLR8 TNFAIP8L2 TNFRSF10C TREM1 TREML2 TYROBP VAV1 XPO6 ZDHHC18 ZNF467 Thyroid Female 20-29 Up ADM2 ATP13A4 BMF BMP8A C16ORF89 COL23A1 CROT CRYGN CYTH2 DGKI DIO1 DUOX2 EBF4 EPOR EXOC3L2 FGFRL1 FLT4 FOXE1 FREM2 FRMPD3 FSCN2 GFRA2 GRK1 HHEX HHIPL2 HIRA HOOK3 IL15 INPP5J IQCA1 ISM1 IVD IYD KCNJ16 KLHL14 KNSTRN LCN12 LIPG LPCAT2 LRP8 LRRC75B MBD6 MGAT4C MROH1 MSANTD2 MUC15 NKX2-1 NPNT OR11L1 OR2A1 OR2T8 PAX8 PBX4 PDE8B PKHD1L1 PLA2G6 PLEKHG4B PLEKHH1 PLVAP PPP1R13B PRKX PRR20E PRTG RASSF4 RCBTB1 RGL3 S100A5 SALL1 SALL4 SCUBE3 SCX SEMA3D SH3D21 SHISA2 SLC12A8 SLC16A11 SLC25A29 SLC25A45 SLC26A4 SLC26A7 SLC4A11 SLC4A5 SLC5A5 SLC5A8 SNX1 SNX22 SORD TECTB TG TMEM50B TPMT TPO TRIB1 TSHR WDR72 ZBED2 ZNF114 ZNF486 ZNF737 ZNF804B Artery - Aorta Female 20-29 Up ACKR4 ADAMTSL3 ADRA1B ADRA1D ADRA2C ANKH ANO1 AQP1 ASPN BGN C1QTNF2 CD151 CNTN4 COL14A1 COL21A1 CPXM2 CRISPLD1 CYTL1 EFEMP1 ELN ERG EXT1 FBLIM1 FBLN5 FGL2 FIBIN FILIP1L FMO4 FOXC1 GABRR1 GDF7 GEM GLIPR1 GLT8D2 HAPLN1 HMCN1 IGFBP7 IL31RA ITGA10 ITGA11 ITGA8 ITGA9 KANK1 KCNK17 KLHL42 LDOC1 LGR6 LIMS4 LOXL1 LTBP1 LTBP2 LTBP3 MAN2B2 MEGF6 MFAP4 MFGE8 MGP MMP23B MRAP2 MTUS2 MYH10 MYH9 MYOCD NPR1 NTN1 NXPH3 OGN OMD OSR1 PCDH7 PCDHB11 PDE5A PID1 PKD2 PLD5 PLS3 PRDM16 PRDM6 PRKG1 PRSS35 PTGIR PTGIS PXDC1 SCUBE3 SEMA3D SFRP1 SHROOM3 SLC16A4 SLC22A3 SLC41A2 SMOC2 SOD3 SPARCL1 ST6GAL2 SUSD5 THRB TPH1 VCAN WWP2 ZNF385D Adrenal Gland Female 20-29 Up AADAC ABCB1 ABCC3 ABCF3 ACSF2 ADGRV1 AKAP7 AKR1B1 ALAD ALAS1 AMHR2 AOX1 AS3MT ASB4 C2CD2 CELA1 CLRN1 CREBL2 CTNNAL1 CTSA CYB561A3 CYB5B CYP11A1 CYP11B1 CYP17A1 CYP21A2 CYP2W1 CYSLTR2 DDB1 DEXI DHCR24 DLK1 EBP EPHX1 FAM166B FDX1 FDXR GALM GNS GRAMD1B GSTA1 GSTA3 GSTA4 GSTA5 HDHD3 HSD3B2 IDH1 INHA KCNJ5 KCNK3 KCNN2 KCNQ1 KLHDC8B KLHL4 LONP1 MAP3K15 MAP3K5 MGARP MRAP MRPL33 MRPL49 NR0B1 NR5A1 PAPSS2 PEBP1 PEG10 PEX3 PLBD2 PLEK2 PLEKHA5 PORCN PPIF PRDX3 RARRES2 RBBP7 RDX RGN RMDN2 SCARB1 SERPINA5 SLC16A9 SLC40A1 SLC46A1 SLC47A1 SLC8B1 SNTB1 SOAT1 SREBF1 STAR SULT2A1 TBX3 TDGF1P3 TKFC TM7SF2 TMEM138 TMEM150C TSPAN12 ZNF275 ZNF280A ZSWIM5 Heart - Atrial Appendage Female 20-29 Up ACTC1 ADAMTS7 ADGRD1 ADRB1 ALPK2 ASPG B3GALT2 BCO2 BMP10 C14ORF180 C6 CASQ2 CCDC141 CIB2 CLGN CORIN CPNE5 CRIP2 CSDC2 CYCS DAND5 DHRS7C DKK3 EDA EIF1B FAM216B FBXO40 FGF12 FITM2 GATA4 GJA5 GJD2 GPD1L GRXCR2 HCN4 HHATL HRC HSPB3 ITGB1BP2 KCNIP2 LAPTM4B LPAR3 MDH1 METTL7B MLYCD MTUS2 MYBPC3 MYBPHL MYH6 MYL4 MYL7 MYLK3 MYOZ2 MYZAP NDUFA1 NDUFA4 NDUFA8 NDUFAB1 NDUFB1 NEBL NKX2-5 NKX2-6 NMRK2 NPPA NRTN OR10P1 OR8B8 OTOGL PAM PDHA1 PKP2 PLA2G5 PRKAG2 PXDNL RABGAP1L RBM20 RD3L RILPL1 RYR2 SBK2 SBK3 SCN5A SGCG SHD SLC25A4 SLC41A1 SLC4A3 SMPX TBX20 TBX5 TECRL TMEM178B TMEM182 TNNI3K TNNT2 UQCRB VWDE WASHC2A WNK2 WNT9B Artery - Coronary Female 20-29 Up ACTA2 ANTXR1 ART4 ASPN ATP10A CACNA1C CCDC3 CNNM2 COL21A1 COL4A1 COL4A2 COL4A4 CPXM2 CRIP1 ECM2 FBLIM1 FMOD FRK GJA5 HEYL HTR1B IGFBP7 ITGA1 KCNA5 LCN10 LCN6 LGR6 LRRC17 LTBP1 MAP3K7CL MCAM MEGF6 MFGE8 MSC MTHFD1L NTRK3 OGN OMD PPP1R14A PTGIS RASSF3 ROR1 SMIM10 ST6GAL2 ST6GALNAC5 STK38L TAGLN TBX18 TGM2 TINAGL1 TRABD2B TRAF5 VCAN WFDC1 Heart - Left Ventricle Female 20-29 Up ACO2 ACTC1 ANKRD1 ASB18 B3GALT2 BSG BZW2 CASQ2 CCDC141 CDH2 CKMT2 COX5A COX7B CPT1B CRYAB CSRP3 CYP2J2 DAND5 DECR1 EIF1B ERVMER34-1 FABP3 FGF18 FHL2 FHOD3 FITM2 FLNC GJA3 GOT1 HADHB HOGA1 HRC HSPB3 HSPB7 IGSF5 ITGB1BP2 LAPTM4B LARGE1 LRRC10 LSMEM2 MDH1 MFN2 MLYCD MPC1 MT1HL1 MTUS2 MYBPC3 MYH7 MYH7B MYL12A MYL2 MYL3 MYOM1 MYOM2 MYOZ2 MYZAP NDUFA1 NDUFS6 NEBL NKX2-5 NMRK2 NUDT4 OGDH OXCT1 PDE1C PDHA1 PDLIM5 PKP2 PLCL1 PLN POPDC2 PTDSS1 RBM20 RD3L RYR2 SCN10A SCN5A SDHA SGCG SLC25A4 SLC41A1 SLC4A3 SLC8A1 SMPX SMYD1 SMYD2 SRL ST8SIA2 SYNPO2L TECRL TENM2 TNNI3 TNNI3K TNNT2 TPM1 TRIM55 UQCRC1 UQCRHL XIRP1 XPR1 Esophagus - Muscularis Female 20-29 Up AARD ABCC1 ACTG2 ACTN1 ADAMTSL1 ADCY5 ADH5 ADRB3 ALDH1B1 ANKS1A ANTXR2 ARHGEF26 ARMC9 ARSB ATL2 BCHE BTC CACNA1H CACNB2 CALD1 CCDC69 CHRM3 CNTNAP3 CNTNAP3B COL4A5 COL4A6 CSRP1 CYSLTR1 DAAM2 DENND2A DGKG DPYSL3 EML1 EPHA7 FAM83D FBXO30 FGL2 FNBP1 FOXF1 FOXF2 FOXP1 GPC4 HLF HOXA4 HPSE2 HTR2B IL33 IQCJ-SCHIP1 ISOC1 ITGA1 JPH2 KANK2 KCNMB1 KCNQ4 KIAA0753 KITLG KLHL23 KLHL42 LHCGR LPP LSM11 MRGPRF MYH11 MYLK NKX6-1 NRP2 NTN1 PALLD PARVA PCDHAC1 PDE5A PGM5 PLEKHO1 PPP1R12A PRKG2 PRUNE2 PYGB RARB RBPMS RGMB RGS2 S1PR3 SEMA3A SEMA3E SGMS2 SLC27A6 SLC2A12 SLITRK3 SMTN SORBS1 STON1 SYDE2 SYNM SYNPO2 TPBG TRPC6 TTC23 WLS WWTR1 ZNF503 Esophagus - Mucosa Female 20-29 Up A2ML1 ADGRF1 ADH7 ALDH3A1 ANXA1 C1ORF116 C6ORF132 CAPN1 CAPN14 CD24 CLCA4 CRABP2 CRNN CSTA CSTB CYSRT1 DEFB104A DEFB104B DSC2 DSG3 DYNAP ECM1 EHF EMP1 ENDOU EPGN EPHA1 ESPL1 FGFBP1 FUT3 FUT6 GBP6 GDPD3 GJB2 GRHL3 GSTP1 IL1A IL1RN IL36A KLK10 KLK13 KRT13 KRT4 KRT78 LYPD2 MALL MUC21 NAA20 NMU OTOP3 PADI1 PAX9 PITX1 PPL PRSS22 PRSS27 PTK6 RAB10 RAB25 RABGGTA RAET1E RAET1G RAET1L RHCG RNF223 S100A14 S100A16 S100A2 SAMD9 SCEL SERPINB1 SERPINB13 SERPINB2 SIM2 SMAGP SPINK5 SPRR1A SPRR2A SPRR2D SPRR3 TACSTD2 TGM1 TGM3 TMEM40 TMPRSS11A TMPRSS11B TMPRSS11D TMPRSS11E TMPRSS11F TMPRSS4 TRIM16 TTC22 TTC9 TXN TXNDC17 UGT1A7 VPS4B VSIG10L ZDHHC13 ZNF185 Esophagus - Gastroesophageal Junction Female 20-29 Up AARD ACTG2 ADCY5 ADH5 ADRB3 ANKS1A ANTXR2 ARRB1 ATL2 BARX1 BCHE BTC CACNA1H CACNB2 CHRM3 CKB CNN1 COL4A5 COL4A6 CSRP1 CYSLTR1 DGKG DISP1 DMPK DNAJB5 EML1 EPHA7 FGL2 FLNA FOXF1 FOXF2 GADL1 GPC4 GRPR HIF3A HLF HOXA2 HOXA3 HOXA4 HOXB4 HPSE2 INAFM2 INPP5A ISL1 JPH2 KCNMB1 KCNQ4 KIAA0753 KLHL42 MAGEB17 MAMDC2 MEIS1 MRGPRD MRGPRF MYH11 MYL6 MYL9 MYLK MYOC NKX6-1 NRP2 NTN1 OCRL PALLD PARVA PCDH7 PDE5A PDLIM7 PDZRN3 PDZRN4 PGM5 PLEKHO1 PPP1R12A PRDM8 PRUNE2 RAB9B RBPMS RBPMS2 RNF150 ROR2 RSPO2 S1PR3 SEMA3A SEMA3E SETD1B SLITRK3 SMTN SORBS1 SPON1 SRF STON1 SYNM TAF9B TEAD3 TGFB1I1 TMEM252 TPM2 TTC23 WLS ZHX3 Stomach Female 20-29 Up A4GNT ADAM28 ADH1C AGR2 AKR1B10 AKR7A3 AKR7L ALDH1A1 ANKRD22 ANXA10 ARL14 ARSD ATP4A ATP4B B3GNT3 B4GALNT3 BARX1 C9ORF152 CA2 CA9 CAPN13 CAPN8 CAPN9 CCKAR CCKBR CHIA CLDN18 CLIC6 COL2A1 CTSE CXCL17 CYP2S1 CYSTM1 DUOXA2 EPN3 ESRRG FAM3B FER1L6 FMO5 FOXA2 FOXA3 FOXQ1 GALE GAST GCNT4 GHRL GKN1 GKN2 GPER1 GPRC5C KCNE2 KPNA7 KRTCAP3 LGALS9C LIPF MCIDAS MECOM MFSD4A MLNR MUC1 MUC5AC MUC6 MYH13 NBPF12 OSBPL7 PALM3 PDILT PGA3 PGA4 PGA5 PGC PIK3C2G PSCA RASSF6 REP15 RFLNA RFX6 S100P SLC26A9 SLC5A5 SLC9A2 SLC9A4 SMIM22 SST SULT1C2 TFF1 TFF2 TMED6 TMEM92 TOX3 TPCN2 TRIM50 TRIM73 TRIM74 UGT1A6 VILL VSIG1 VSIG2 VWA2 XYLT2 Adipose - Visceral (Omentum) Female 20-29 Up ABHD15 ACACB ACO1 ACOT2 ACSL1 ADAMTS15 ADIPOQ AGPAT2 AIFM2 ALDH1A3 ALDH1L1 ANGPTL4 AOC2 APOL4 AQP7 BDKRB1 C14ORF180 CCDC71L CDC42EP2 CDC42EP4 CDKN2C CIDEA CIDEC COL4A1 CPXM1 CTSL DCUN1D3 DGAT2 DUSP4 DUSP6 ECHDC3 ELOVL5 ESYT1 FAH FAM89A FASN FGFRL1 FOSB FOSL1 G0S2 GFPT2 GGCT GHR GLUL GPAM GPBAR1 GPD1 GYG2 HADH HAS1 HEBP2 IGF1 KLB LGALS12 LIF LIPE LPL MAP3K8 MDFI MEDAG MEST MMP19 MRAP MT1A MT1E MT1M MYC NEURL2 NMB NOCT NWD2 NXNL1 PC PIM1 PLAU PLIN1 PLTP PNPLA2 PPARG PPP1R15B PRDX6 PRKAR2B PRRT4 RDH5 RETSAT SLC16A7 SLC19A3 SLC25A1 SLC7A10 SMIM3 SOCS3 SPSB1 SRPX STAT5A TIMP4 TM4SF1 TMEM132C TSKU UAP1 ZBED3 Skin - Not Sun Exposed (Suprapubic) Female 20-29 Up ABCA12 ACER1 ADGRF4 ADRB2 AHNAK2 ALOX12B ARHGEF19 ASCL2 ATP6V1C2 BCL11B BLMH BNIPL BPIFC C11ORF80 C1ORF74 CALML5 CAMSAP3 CASP14 CERS3 CHP2 CLDN1 COL17A1 COL7A1 CPA4 DLX5 DMKN DSC3 DSP ELOVL4 EPHB6 EPPK1 ETV3 FAM83F FAM83G FGFR3 FLG2 GAL3ST4 GAN GJB3 HOPX HR IFFO2 IL17RE IL20RA IL20RB IRX3 KLC3 KLF3 KLF4 KRT14 KRT77 KRTDAP KY LAMB4 LGALSL LIPK LIPM LIPN LY6G6C LYPD5 LYPD6B MFSD2A MLANA MYC MYCL NIPAL4 NKPD1 OVCH2 OVOL1 PKP1 PLA2G4F PNLIPRP3 PNPLA1 RAPGEFL1 RORA SBSN SDR42E1 SERPINB12 SERPINB5 SIK1 SLC24A5 SLC46A2 SPINT3 SPTLC3 SPTSSB TET3 TFAP2A TGM5 THEM5 TINCR TNS4 TREX2 TRIM35 TRPM1 TYR WEE1 WFDC5 XG ZNF273 ZNF750 Breast - Mammary Tissue Female 20-29 Up AACS ABCC11 ACLY ADGRD2 ALDH1A3 ALX4 ANKRD30A ANO1 APOL4 ARHGAP8 ARHGEF38 ATP13A5 AUTS2 BTN1A1 C6ORF15 CAPN6 CCL28 CITED4 CLDN8 CMTM7 CMTM8 CPSF4L CRACR2B CSN1S1 CSN2 CSN3 CX3CL1 CYP4Z1 DUSP23 DUSP4 ELF5 ETV3L FASN GABRP GSC HCAR1 HSD17B2 IL17RD IL22RA2 IRX1 IRX2 IRX5 KCNN4 KCTD14 KIT KRT19 KRT7 LALBA LAMC2 LHFPL2 LMX1B LOXL4 LTF MMP7 MTHFD2L MUCL1 NEURL3 NFATC2 NFIB NPFFR2 NPSR1 NTF4 NTN4 OBP2B OVCH2 OXTR PLEKHS1 PLPP2 POU5F1B PROM1 PYROXD2 RUNX1 SERINC2 SFRP1 SH3D21 SLC26A5 SLC28A3 SLC5A6 SPTSSA STAC2 STAT5A TFAP2B TFAP2C TIGD2 TMPRSS3 TRPS1 VGLL1 VTCN1 XDH ZNF552 Colon - Transverse Female 20-29 Up ADTRP AGR3 ANKDD1B ATOH1 ATP10B ATP2C2 ATP8B1 B3GNT6 B4GALNT2 BCL2L15 BEST2 C15ORF48 CA1 CA7 CALML4 CASP6 CCL15 CDC42EP5 CDH17 CDX1 CDX2 CEACAM5 CEACAM7 CES3 CLCA1 CLDN3 CLDN7 CLRN3 DQX1 DSG2 EFNA2 ENTPD8 EPCAM EPHB2 EPS8L3 ETHE1 FABP1 FCGBP FXYD3 GAL3ST2 GPA33 GPR35 GUCY2C HEPACAM2 HHLA2 HOXB9 HSD11B2 HTR3E IHH ISX KRT20 KRT8 LEFTY1 LGALS4 LRRC19 LRRC31 LYPD8 MARVELD3 MIER3 MISP MS4A12 MTMR11 MUC12 MUC13 MUC4 NANS NOX1 NXPE1 NXPE2 NXPE4 PHGR1 PIGR PLA2G10 PLS1 PPP1R14D PRELID2 PRR15 PYY REP15 RETNLB RXFP4 SATB2 SELENBP1 SLC26A2 SLC26A3 SLC35A3 SLC44A4 SLC9A2 ST14 ST6GALNAC1 TMEM236 TRABD2A TSPAN1 TSPAN8 UGT1A10 UGT1A8 UGT2A3 UGT2B17 URAD ZG16 Colon - Sigmoid Female 20-29 Up ACTG2 ATP2B4 BAG2 BCHE BMP3 BTC C3ORF70 CACNA1C CACNA1H CCL11 CDK8 CHRM2 CNN1 CSRP1 EMILIN1 EML1 FBXL22 FOXF1 FOXP2 FZD7 GJC1 GLP2R GPR17 GREM2 HAND1 HAND2 HDAC4 HMCN2 HOXA13 HOXD11 HOXD12 HOXD13 INAFM2 ITGA5 KCNMA1 KCNQ4 KIZ KLHL23 KLHL5 LBR LIMS2 LIPI LRCH2 LRIG1 MAB21L2 MASP1 MDM1 METTL24 MICALL1 MID1 MRGPRD MRGPRF MYH11 MYLK NKX2-3 NKX3-2 NPY4R NRP2 NT5DC3 NTSR1 NXN PDE3B PDLIM7 PDZRN4 PGM5 PHOX2B PLA2G2C PLEKHO1 PNCK PTBP2 PTCHD1 PTGFRN PTGS1 QRFP RAB23 RNF150 ROR2 RPRM RSPO2 SEMA3A SEMA3C SLMAP SMTN SOX11 SPOP STON1 SYDE2 SYNM TACR2 TBC1D1 TEAD3 TES TGFB1I1 TMEM252 TMEM35A TMTC2 TNC TNFAIP8L1 TSPAN2 UBXN10 Ovary Female 20-29 Up ACSM3 ADAMTS16 ADRB3 ANGPTL5 ARX ASIP BAMBI BNC2 BST2 CDH11 CDH23 CHST7 CLSTN2 COLEC11 CPZ CRYGD CTH DAPK1 DPPA3 ECEL1 EML5 FFAR1 FIGLA FOXL2 FOXL2NB GATA4 GATA6 GLI2 GREB1 GSTM5 HS3ST1 HS6ST2 IGDCC4 IGFBP5 IGSF10 INHA KLHDC8A KPNA7 LAG3 LHX9 LPAR4 LRRC17 MCC MDK MEX3A MMP21 MMP23B MSH6 NDNF NECAB3 NLGN4X NLRP13 NLRP5 NLRP9 NOBOX NR2F2 NRK NYNRIN OBSL1 OSR2 PADI6 PDGFRA PEG3 PIWIL3 PRDM5 PRMT9 PROK1 PRPS2 RASL11B RBP1 RHBG SIGLEC11 SIGLEC16 SIMC1 SLC25A17 SLC8B1 SNCAIP SOX4 ST13 SULF2 SYTL4 TBPL2 TCEAL1 TCEAL4 TDGF1P3 TENM4 TMEM98 TRABD2A TRIB2 TSHZ1 TSHZ3 TTC8 UBXN8 VLDLR WFIKKN2 WIPF3 ZDBF2 ZNF66 ZP3 ZP4 Vagina Female 20-29 Up A2ML1 ADAMTSL5 ADGRF1 ALOX12 ANXA8 BDKRB2 C16ORF74 CLCA2 CLIC3 CNFN CPA6 CRABP2 CRCT1 CROT DSC2 DSG3 EDN2 EDN3 EHF EMP1 EPHA1 ESR1 EVPLL EVX1 FABP5 FAM83A FGFBP1 GALNT5 GJB2 GJB6 GPR87 HCG22 HEPHL1 HES2 HOXA13 HOXD10 HOXD11 HOXD12 HOXD13 HOXD9 HPGD IL17A ISL1 ISL2 IVL KLK10 KLK11 KRT13 KRT6A LCE3A LCE3D LPAR5 MALL MASP1 MAST4 MPZL2 MUC22 NUAK2 PGLYRP3 PLA2G4D PPL PRDM1 PRLHR PRRG4 PRSS12 PRSS22 PRSS27 RAET1E RHCG RNF223 S100A7 S100A7A S100A8 SALL3 SERPINB13 SERPINB3 SERPINB4 SLC18A2 SMAGP SOX7 SPINK5 SPINK6 SPINK7 SPRR1B SRD5A3 SULT1E1 TACSTD2 TGFA THSD4 TMPRSS11A TMPRSS11D TMPRSS11E TMPRSS11F TP53AIP1 TP53I3 TPRG1 TRIM16 TTC22 UPK1A ZNF185 Uterus Female 20-29 Up ADAMTS19 AKAP13 ALDH1A2 ALX3 ATP2B4 AXIN2 BNC2 CAPN6 CDKL1 CHRDL2 CUX1 DCHS1 DPP6 EDNRA EMX2 ENPP1 EPHB4 ESR1 FBXL22 FRMD7 GAS1 GATA2 GJC1 GLB1L2 GNA14 GPR161 GUCY1A2 HOXA10 HOXA11 HOXD10 HOXD11 HOXD3 HOXD4 HOXD9 HUNK IGFBP5 IL17RD ISLR ISOC1 JAZF1 KCNE4 KCNG1 KCNMA1 KLHL13 LEFTY2 LINGO2 MAMDC2 MASP1 MATN2 MEIS3 MITF MMP26 MOXD1 MRGPRF MYADM OSR2 PAEP PBX1 PGR POMGNT2 PRLR PTGER3 PTK7 RAB23 RAD51B RAMP1 RAP2C RERG REV3L RSPO1 RSPO3 SCGB1D4 SCGB2A1 SERTM1 SLC24A3 SLC37A3 SLC7A3 SNCAIP SOX4 SPON2 SSC5D STK26 SULF2 SYTL4 TAB3 TBC1D1 TBL1X TCEAL4 TCF23 TMEM123 TMEM158 TMEM200A TMEM200B TNFAIP8L3 TRPC4 TSHZ3 WT1 XKR5 ZDHHC14 ZNF516 Muscle - Skeletal Female 20-29 Up ACTA1 ACTN2 ALPK3 AMFR ANKRD23 ANKRD39 ART1 ASB12 ASB2 ASB8 ATP2A2 BIN1 BTBD1 CACNG1 CACNG6 CAND2 CHRNA10 CKM CMYA5 COQ8A DCAF6 DDIT4L DUSP13 EGLN1 ENO3 EYA4 FBXO32 FEM1A FHL3 GMPR HADHA IDI2 IGFN1 IP6K3 ITIH6 JPH1 JSRP1 KCNA7 KCNJ11 KEAP1 KLHL34 KLHL38 KLHL40 KLHL41 LBX1 LPIN1 LRRC2 MAPK12 MKNK2 MRLN MYBPC1 MYLK4 MYO18A MYOT MYPN NFE2L1 NT5C1A OBSCN OPTN OSBPL11 PCNT PDE4DIP PERM1 PHKA1 PHTF2 PLPP7 POPDC3 PRKAG3 PRKAR2A PROB1 PYGM RAD23A RAPSN RASA4B RNF123 RPL3L SCN4A SH3BGR SIX1 SIX4 SLC29A2 SMTNL2 SPTB SYPL2 TBX15 TMEM201 TMEM233 TMEM38A TMOD4 TPM3 TRIM54 TRIM63 UBR3 UCP3 USO1 USP13 UTP11 YBX3 ZNF106 ZYG11B Artery - Tibial Female 20-29 Up ACTA2 ACTN4 ADARB1 ADIRF AMIGO2 ANGPTL1 ARTN ATL3 AVPR1A BCAM C11ORF96 C1QTNF1 CCDC107 CDH6 CLIC4 CNNM2 COL14A1 CPED1 CRLF1 CRTC3 CSRP1 CSRP2 DACT3 DSTN EFHD1 ESD FBXL3 FHL5 FOXC1 FOXC2 FRK FRY HES4 HEY2 HTR1B ITGA5 JAG1 JAK2 KCNA5 KCNAB1 KCTD10 KLHL26 LMOD1 LPP MAP7D3 MCAM MOB2 MSRB3 MTHFD2 MUSTN1 MYL9 NKD1 NOTCH3 NTF3 NTRK3 P2RX1 PACSIN2 PCSK7 PDK3 PITPNB PLCE1 PLEKHG3 PPP1R14A PRKG1 PTK2 RASL12 RASSF3 RHOB RNF180 ROCK1 ROR1 RRAS SBDS SDK1 SELENOM SH3BGRL SLMAP SMIM10 SMURF1 SORBS1 SORBS2 SPOPL SSBP3 STS TAGLN TASP1 TBX18 TBXA2R TGM2 TLN1 TMEM181 TMEM38B TMTC1 TNC TNS1 TRABD2B TSC22D1 UBA2 WDR1 ZFHX3 Adipose - Subcutaneous Female 20-29 Up ABCD2 ABHD15 ACACB ACO1 ACVR1C ADH1B ADIPOQ ADRA2A AGPAT2 AIFM2 AKR1C2 ANGPTL4 APOL6 AQP7 BCAP31 BNIP3L C19ORF12 CAT CD248 CD300LG CD36 CDKN1C CEBPA CIDEA CIDEC CPM DOCK11 ECHDC3 EGFL6 EGFLAM ELOVL5 ESYT1 FABP4 FAH FAM89A FZD4 G0S2 GABRE GGCT GHR GPAM GPBAR1 GPD1 GPR146 GYG2 HEBP2 HNMT ITGB1BP1 ITIH5 ITSN1 KLB LEP LGALS12 LIPE LPL LVRN MAP1LC3C MEOX1 MEST MGLL MOCS1 MT1A MYEOV NANOS1 NMB NMT2 NXNL1 ORMDL3 PDE3B PECR PEX11A PEX19 PHLDA3 PLIN1 PLIN4 PLXNA4 PNPLA2 PPARG PRKAR2B PTGER3 RBP7 RDH5 RETSAT SCD SEMA3G SIK2 SLC19A3 SLC25A1 SLC29A4 SLC35C1 SLC7A10 SMIM3 STAT5A SYNE3 TLCD2 TMEM132C TSKU TSPAN15 UVRAG VKORC1L1 Skin - Sun Exposed (Lower Leg) Female 20-29 Up AADACL2 ABCA12 ACER1 ADGRF4 AHNAK2 ALOX12B ALOXE3 ASPRV1 BNIPL C1ORF68 C5ORF46 C6ORF15 CALML5 CAMSAP3 CASP14 CDSN CLDN1 CTNNBIP1 DAPL1 DCT DLX3 DLX5 DMKN DSG1 DSP EFNA3 EPHB3 EPPK1 FAM83G FGF22 FLG FLG2 GAN GSDMA HELT HOPX HS3ST6 IFFO2 IL17RE IL20RA IL36B IL36RN IL37 KLC3 KLK11 KLK5 KLK7 KLK9 KPRP KRT10 KRT23 KRT80 KRTAP20-1 KRTDAP LAMB4 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE4A LCE6A LIPM LY6G6C LYPD5 MLANA MYCL NKPD1 PERP PKP1 PNLIPRP3 POF1B PPP1R13L PSAPL1 RAB40C RDH12 SBSN SERPINA12 SERPINB8 SLC24A5 SLC46A2 STARD5 TGM5 THEM5 TINCR TMEM86A TMPRSS13 TNS4 TRIM29 TRIM35 TRPM1 TUFT1 TYR XG XKRX Brain - Frontal Cortex (BA9) Female 60-69 Up ADGRA1 AK5 ANKRD24 ATRNL1 BRINP2 CABP1 CACNG3 CACNG5 CADM2 CAMK2A CAMK2N1 CBLN2 CCK CHN1 CLEC2L CNTNAP2 COL26A1 CREG2 CTNNA2 CTXN3 DLGAP1 DPP10 EIF4E1B ELAVL4 ENC1 EPHX4 FAM163B FAM217B FAM81A FXYD7 GABBR2 GABRG2 GLRB GRIA3 GRIN2A HAPLN4 HCN1 HECW1 HS3ST2 HTR2A KCNC2 KCNH5 KCNS1 KCNS2 KCNV1 KCTD16 KIAA1549L KIF5A LCN15 LHX2 LINGO1 LMO4 LRFN2 LRFN5 MAPK10 MCF2L2 MCHR2 MGAT5B MPPED1 NAP1L2 NAP1L3 NECAB1 NEFL NEFM NRCAM NRG3 NRGN OLFM1 OLFM3 PDE6H PLEKHM2 PNMA6A POU6F2 PRKAR1B PTPRT RAPGEF4 RGS4 RIMS3 RORB RPH3A RXFP1 SCG3 SCN1A SERPINI1 SLC35F1 SLC39A12 SNCB SOHLH1 SULT4A1 SYN1 SYT1 SYT13 SYT16 TBR1 TESPA1 TMEM132D VSNL1 YWHAH ZDHHC22 ZNF365 Brain - Cerebellar Hemisphere Female 60-69 Up ADAM22 AKAIN1 ALS2 BARHL1 BARHL2 CA10 CACNA1A CADPS2 CALN1 CAMK4 CBLN1 CBLN3 CCDC175 CHD7 CHN2 CKMT1B CLVS2 CNPY1 CNTN6 CRTAM DIRAS2 DISP2 EN2 EPB41 ETV1 FGF17 FSTL5 GABRA6 GABRD GALNT13 GPR137C GPR158 GRIA4 GRIK2 GRM1 GRM4 IFNA8 KCNA1 KCNAB3 KCNC1 KCND2 KCNJ3 KCNK9 LCN8 LHX1 MAB21L1 MDGA1 MEGF11 MMP24 MTCL1 MYT1 NEUROD1 NEUROD2 NKX6-3 NPFFR1 NPTX1 NRXN3 PAK5 PAX6 PCDHGC4 PKIB PPFIA4 PRR35 RAB26 RBFOX3 RELN RIT2 SCN2A SCRT2 SHF SHISA8 SLC22A31 SLC35F4 SRRM3 SRRM4 STXBP5L SYT2 SYT4 TIAM1 TMC2 TMEM145 TMEM178A TMEM266 TRIM11 TRIM67 TRPM3 TUBA8 UNCX VAX2 VSX1 VWC2 ZBTB18 ZFYVE28 ZIC1 ZIC2 ZIC3 ZIC4 ZIC5 ZNF382 ZNF521 Brain - Substantia Nigra Female 60-69 Up ADARB2 ANKRD40 BAALC BCAS1 C10ORF105 CARNS1 CCDC160 CCDC163 CERS1 CHRNB3 CHST6 CLDND1 CLEC19A CNP CNTN2 CNTNAP4 CTNNA3 DBNDD2 DBX2 DNER DYNC1LI2 ENHO ERMN FEZ1 FGF1 FOXB1 GALNTL6 GFAP GLRA1 GPR26 HAPLN2 HIPK2 HMX1 ITPKB KCNE5 KCNG4 KCNJ6 KIF6 KLHL1 LHPP LMX1B LPAR1 LRRC55 LUZP2 MAP4K4 MBP MOBP MOG MT3 MTURN NIPA1 NKAIN2 NKX6-2 NTSR2 OC90 OLIG1 OLIG2 PAAF1 PAIP2B PAQR6 PAQR8 PHACTR3 PIP4K2A PIRT PKP4 PLEKHB1 PMP2 PRR18 PSRC1 QDPR RAB11FIP4 RET RFTN2 RND2 ROM1 RPE65 S100B SCD5 SHISA6 SHTN1 SLAIN1 SLC10A4 SLC5A11 SLC6A11 SLC6A3 SLCO1A2 SOX8 SPOCK3 SPX TH TMEM144 TMEM229A TMEM235 TMEM255A TNR TP53INP2 TRIL TRIM41 TSC22D4 ZNF488 Brain - Hypothalamus Female 60-69 Up ACHE ADCYAP1 AGRP AIRE B3GAT2 BSX CALB2 CALCR CALY CFC1 CLEC19A CNGB1 CSMD3 CXXC4 DIRAS3 DLX1 DLX2 DNER ECE2 ECEL1 ELAVL2 ENKUR ERAS FBLL1 FNDC9 FOXB1 GABRA3 GABRG3 GABRQ GBX2 GFAP GHRH GLRA2 GNG8 GRIK1 GRIN2D GSX1 HAP1 HCRT HCRTR2 HDC INPP5F KISS1R KLHL32 LHX5 LRAT LRRC55 LUZP2 LY6H MAGEL2 NAP1L3 NAP1L5 NGB NMS NPSR1 NPVF OLIG1 OR12D1 OR12D2 PABPC1L2A PABPC1L2B PIRT PMCH PNMA5 PODXL2 PRDM12 PRDM13 QRFPR RAB3C RND2 RPE65 RTL1 RTP5 SCG2 SCN9A SLC17A6 SLC6A11 SMIM18 SNCG SOX1 SOX11 SOX3 SV2C SYNGR3 SYT6 TACR3 TCEAL7 TMEM114 TMEM17 TMIE TUBB3 UCHL1 UNC5D VAT1L VGF VSTM5 VWC2L WDR49 ZBTB8B ZCCHC12 Brain - Spinal Cord (Cervical C-1) Female 60-69 Up ABCA2 ADORA3 AGPAT4 ANKRD40 ANLN APLP1 BACE1 BCAS1 C10ORF90 C21ORF91 CA14 CARNS1 CDK18 CHADL CLDND1 CMTM5 CNP CNTN2 CNTNAP4 CTNNA3 DBNDD2 DPYSL5 DTNB ERMN EVI2A FA2H FEZ1 FGFR2 FMNL2 FNTB GAL3ST1 GFAP GJC2 GPM6B GPR151 GPR37 GPR62 HAPLN2 HMSD HOXB8 HOXD1 KLK6 LHPP LRRC63 MAG MAP7 MARCKSL1 MBP MOBP MOG MTMR10 MTURN MVB12B MYRF NIPA1 NKAIN2 NKX2-2 NKX6-2 OR9A2 PACS2 PAIP2B PAQR4 PAQR6 PAQR8 PCSK6 PEA15 PEX5L PIP4K2A PKP4 PLEKHB1 PLP1 PRRG1 PSRC1 RAPGEF5 RASSF2 RBM11 RND2 S100B SAP18 SEMA4D SIGLEC8 SIRT2 SLAIN1 SLC44A1 SLC5A11 ST18 STMN4 SYNJ2 TBC1D12 TF TMEM144 TMEM151A TNFRSF21 TP53INP2 TRAK2 TREM2 TRIM41 TUBA1A UGT8 ZNF488 Cells - EBV-transformed Lymphocytes Male 30-39 Up ADGRG5 AHRR AICDA ANGPTL6 APELA APOBEC3F APOBEC3G APOBEC3H ATAD5 BFSP2 BLM BLNK BRCA2 BTLA C17ORF99 CCNI2 CCR6 CD226 CD27 CD70 CD79A CD80 CD86 CENPM CLEC17A CLEC2D CLNK CPOX E2F7 ESCO2 FAM111B FAM72D FCER2 FCRLA FSBP GCSAM GNGT2 GPR15 GPR55 HLA-DOA HLA-DQA1 HVCN1 IFI44L IKZF2 IKZF3 IL21R IL23R IL4I1 IRF4 IRF5 ITGA4 ITGB7 LGALS14 LPXN LY75 MCM2 MCOLN2 MX1 MYBL2 MYL12BP2 NUP210 OAS2 OAS3 OR2T3 P2RY10 PAX5 PI4K2B PIK3R6 PLCG2 PNOC POU2AF1 PTPN22 RAD54B SCIMP SERPINB10 SIT1 SKAP1 SLAMF1 SLAMF7 SNX25 SP140 SPIB SPN STAP1 STAT1 TCL1A TIFA TLR10 TLR7 TMSB15B TNF TNFRSF13B TNFRSF17 TNFRSF8 TNFSF9 TSPAN33 USP18 WDFY4 WNT10A ZNF318 Whole Blood Male 30-39 Up ABTB1 ADAM8 ADGRE3 ADGRG3 ALOX5 ALOX5AP AOAH AQP9 ARHGDIB ARL11 BIN2 BST1 C16ORF54 C19ORF38 C5AR2 CDA CEACAM3 CEACAM4 CFP CLEC4E CSF3R CYBA CYTH4 DOK3 DPEP2 EVI2B FCER1G FCGR2A FGD3 FGR FPR1 FRAT2 FUT7 GCA GLT1D1 GMIP GPR141 GPSM3 GRK6 HCK HRH2 ICAM3 IL17RA IL18RAP ITGAM JAML LAT2 LILRA1 LILRA2 LILRA5 LILRA6 LILRB2 LY6G6F MEFV MNDA MSRB1 MYD88 MYO1F NCF1 NCF2 NFAM1 NFE2 NLRC4 NLRP12 OSCAR P2RY13 PADI4 PGLYRP1 PLBD1 PRAM1 PSTPIP1 R3HDM4 RASGRP4 RGS19 RIN3 RPS6KA1 S1PR4 SELL SELPLG SIGLEC5 SIGLEC9 SIRPB1 SIRPB2 SLC12A9 SLC25A37 TBXAS1 TLR5 TLR8 TMEM71 TNFAIP8L2 TNFRSF10C TREML1 TREML4 TUBB1 TYROBP VAV1 VSIR VSTM1 XPO6 ZDHHC18 Cells - Cultured Fibroblasts Male 30-39 Up ADAM12 ADAM9 ADAMTS2 ADM ALDH1L2 ANXA5 ARSJ AZI2 BRIX1 C6ORF120 CALU CCBE1 CCDC80 CD109 CEMIP CITED2 CLEC11A COL11A1 COL12A1 COL1A1 COL1A2 COL5A1 COL5A2 COL6A3 CTHRC1 DKK1 DSEL EIF2AK4 FAP FBN1 FBN2 FKBP10 FKBP14 FN1 FRMD6 FZD2 GCNT1 GOPC GPR176 GPX8 GREM1 HIF1A HOXC8 HS3ST3B1 IGF2BP1 IGF2BP2 IGF2BP3 IKBIP KCNK2 KDELR2 KDELR3 LOX LOXL2 MME NECTIN3 NID2 OLFML3 OR1J4 OR1Q1 OSTC PAPPA PCDH18 PCDHGA11 PCDHGB4 PCOLCE PLOD1 PLOD2 PRR16 PSG4 PSG5 PTX3 PXDN RCN1 RCN3 RECK SEC22B SERPINH1 SLC1A5 SNAI2 SNAPC1 SRGAP1 STC2 STEAP1 STT3A TGFBI THBS1 TMEM119 TNFRSF10D TPM4 TRAM1 TRAM2 TWIST1 TWIST2 TXNRD1 ULBP1 VGLL3 WNT5A XPOT YIPF5 ZNF281 Adrenal Gland Male 30-39 Up AADAC ABCB1 ABCC3 ADGRV1 AKAP7 AKR1B1 ALAD ALAS1 AMHR2 AOX1 APOE AS3MT ASB4 C2CD2 CDH12 CEACAM16 CELA1 CLRN1 CREBL2 CTNNAL1 CTSA CYB561A3 CYB5B CYP11A1 CYP17A1 CYP21A2 DDB1 DHCR24 DLK1 EPHX1 FAM43B FCN2 FDX1 FDXR GALM GIPC2 GNS GSTA3 GSTA4 HDHD3 HIBADH HSD3B2 IDH1 IFITM10 KCNJ5 KCNK3 KCNN2 KCNQ1 KCTD14 KIAA1958 KLHL4 LONP1 LRRN3 MAP3K15 MAP3K5 MCF2 MCOLN3 MERTK MGARP MRPL33 NR0B1 NR5A1 NXPH1 PAPSS2 PDGFD PEBP1 PEG10 PEX3 PHACTR2 PLBD2 PLEKHA5 RARRES2 RBKS RDX RGN RMDN2 RWDD4 SEMA6A SERPINA5 SLC16A9 SLC40A1 SLC47A1 SLC8B1 SNTB1 SOAT1 SREBF1 STAR SULT2A1 TBC1D4 TBC1D8B TBX3 TM7SF2 TMEM150C TPD52L1 TSPAN12 VEPH1 WHRN ZNF275 ZNF280A ZSWIM5 Lung Male 30-39 Up A2M ABCA3 ACOXL ACP5 ACVRL1 ADAMTS8 ADGRF5 ADGRL2 AGER AGTR2 ATP11A BMP5 CACNA2D2 CASS4 CCDC102B CCL18 CCL20 CD101 COL6A5 COL6A6 COX4I2 CSF2 CTSH CXCL3 DRAM1 DUOX1 EMP2 EPAS1 FCN3 FGFR4 FLRT3 FOLR1 GGTLC1 GPRC5A HTRA4 ICAM1 IL15RA INMT KCNS3 LAMP3 LPCAT1 LRRK2 LTK MARCO MBIP MRC1 MS4A15 MSR1 MUC1 NAPSA NCKAP5 NDNF NKD2 NPC2 OLR1 OR6K3 OR6N2 PHEX RBMS2 RGCC RHOBTB2 RNF145 ROS1 RS1 RTKN2 SCGB1A1 SCGB3A2 SFTA2 SFTPA1 SFTPA2 SFTPB SFTPC SFTPD SHROOM4 SLC34A2 SLC39A8 SLC6A14 SLC6A4 SLCO2A1 SLCO4C1 SMAD6 SNX30 SPSB2 SUSD2 TBC1D2 TBX2 TBX4 TCF21 TFEC TFPI TMEM100 TMEM125 UNC13B VEGFD VEPH1 VIPR1 WNT2 WNT3A XAGE2 ZNF385B Spleen Male 30-39 Up ANXA2R BANK1 BLK BTN3A1 C1QA C1QB C1QC CABP4 CARD9 CASP10 CCL24 CCM2L CD163L1 CD180 CD19 CD1C CD1D CD22 CD4 CD5L CD72 CD79B CDCP2 CERKL CETP CNR2 CPLX3 CR2 CSF1R CXCL13 CXCL6 CXCR5 DNASE1L3 EMID1 EXOC3L1 FCMR FCRL1 FCRL2 FCRL3 FGD2 FHOD1 FLI1 GAB3 GDPD2 GDPD5 GPR142 GPR182 GRAP HLA-DOB HMOX1 HYAL1 HYAL2 IL10RA IL24 IRF8 ITGAD KAZALD1 LILRA4 LILRB5 LRTM1 LTB MPEG1 MS4A7 MZB1 NLRC3 NOS3 NOX5 NPY1R NR5A1 NTN4 OR5AK2 OR9G4 P2RX5 P2RY6 PARP15 PARVG PDE6G PDLIM2 PITPNM3 PRR5 PSTPIP2 RENBP SCN11A SEMA3D SIGLEC12 SLC9A5 SP140L SPIC STAB1 STAB2 TDGF1 TLX1 TMC8 TMEM156 TMEM26 TNFRSF13C TRAPPC3L TTC24 TXK VCAM1 Liver Male 30-39 Up A1BG A1CF ABCC6 ABCG5 ABCG8 ACADSB ACSM2A ACSM5 ADH1A ADH4 ADH6 AGXT AHSG AKR1D1 ALB AMBP ANGPTL3 APOA2 APOC1 APOC2 APOC3 APOC4 APOM ASGR1 ASGR2 ATF5 C8A C8G CA5A CCL16 CFB CFHR1 CFHR2 CLDN14 CYP1A2 CYP26A1 CYP2E1 CYP4F2 CYP7A1 DCXR DMGDH DNMT3L EHHADH F12 F13B F2 F7 FCAMR GCGR GCKR HAAO HABP2 HAO1 HPD HRG HSD17B13 IGFALS INHBE ITIH1 ITIH2 KDM8 KLKB1 KNG1 LECT2 LIPC LRCOL1 MAT1A MBL2 NPC1L1 NR0B2 NR1I3 PKLR PLG PON1 PROC RBP4 RDH16 RTP3 SERPINA6 SERPIND1 SERPINF2 SLC10A1 SLC13A5 SLC17A2 SLC22A1 SLC22A7 SLC25A47 SLC27A5 SLC28A1 SLC2A2 SLC38A3 SLCO1B3 SPP2 TFR2 TMPRSS6 TTC36 UGT2B15 UPB1 UROC1 VTN Thyroid Male 30-39 Up AFAP1L2 AMELY ATP13A4 BMP8A C16ORF89 CLN5 COL23A1 CPQ CRYGN CTSB CYTH2 DIO1 DUOX2 EPOR EXOC3L2 FOXE1 FREM2 FSCN2 GAL3ST3 GFRA2 GOLGA8M GOLGA8R GRK1 HHEX HIRA HOOK3 IFT140 INPP5J ISM1 IVD IYD KCNC3 KCNJ16 KLHL14 KNSTRN LCN12 LIPG LPCAT2 LRP2 LRP8 MBD6 MGAT4C MPPED2 MROH1 MUC15 NKX2-1 NPNT OR2A1 OR2A42 OR2T8 PARM1 PAX8 PBX4 PCSK2 PDE8B PKHD1L1 PLA2G6 PLA2R1 PLEKHH1 PLVAP PPP1R13B PRKX PRTG RASSF4 RCBTB1 RGL3 SALL1 SALL4 SCX SEMA3D SH3D21 SHISA2 SLC12A8 SLC16A11 SLC17A5 SLC25A29 SLC26A4 SLC26A7 SLC4A11 SLC4A5 SLC5A8 SLCO2A1 SNX1 SNX22 ST3GAL1 SUCNR1 TBL1Y TCERG1L TG TMEM30B TPMT TPO TSHR VEGFA WDR72 WFDC8 ZNF114 ZNF486 ZNF804B ZNF90 Esophagus - Mucosa Male 30-39 Up A2ML1 ADH7 ALDH3A1 ANXA1 AQP3 BARX2 CAPN1 CAPN14 CLCA2 CRABP2 CRNN CSTA CSTB CYSRT1 DSC2 DSG3 DYNAP ECM1 EHF EMP1 ENDOU EPGN EPHA1 EPHA2 FABP5 FAM135A FAM83A FGFBP1 FUT6 GBP6 GJB2 GJB6 GPR78 GRHL3 GSTP1 IL1RN IL36A KLK10 KLK12 KLK13 KRT13 KRT15 KRT4 KRT6A KRT6B LEXM LYPD2 MALL MPZL2 MUC21 NMU OTOP3 PADI1 PAX9 PITX1 PPL PRSS22 PRSS27 RAB10 RAB25 RABGGTA RAET1E RAET1G RAET1L RHCG S100A14 S100A16 S100A2 S100A8 SAMD9 SCEL SERPINB1 SERPINB13 SERPINB2 SERPINB3 SIM2 SMAGP SPINK5 SPRR1A SPRR2A SPRR3 TACSTD2 TGM1 TGM3 TMEM184A TMEM40 TMPRSS11A TMPRSS11B TMPRSS11E TMPRSS11F TMPRSS4 TRIM16 TTC22 TXN TXNDC17 UGT1A7 USH1G VSIG10L ZDHHC13 ZNF185 Esophagus - Muscularis Male 30-39 Up AARD ABCC1 ACTG2 ACTN1 ADCY5 ADH5 ADRB3 ALKAL1 ANKS1A ANTXR2 ARHGAP10 ARHGEF26 ARMC9 ARSB BCHE BTC CACNA1H CACNB2 CALD1 CCDC69 CHRM3 CNN1 CNTNAP3 CNTNAP3B COL4A5 COL4A6 CSRP1 CST5 CYSLTR1 DAAM2 DENND2A DGKG DHX35 DPYSL3 EPHA7 FAM83D FBXO30 FLNA FNBP1 FOXF2 FOXP1 GIPC3 GPC4 HDAC9 HLF HOXA4 HPSE2 INPP5A ITGA1 JPH2 KANK2 KCNMB1 KCNQ4 KIAA0753 KITLG LHCGR LPP LSM11 MYH11 MYL9 MYLK NKD1 NKX6-1 NRP2 NTN1 OCRL PALLD PARVA PGM5 PLEKHO1 PPP1R12A PPP1R12C PRUNE2 PYGB RARB RBPMS RGMB RGS2 S1PR3 SCUBE1 SEMA3A SEMA3E SGMS2 SLC27A6 SLC2A12 SLITRK3 SMTN SORBS1 SRF STON1 SYDE2 SYNM SYNPO2 TEAD3 TPBG TRPC6 TTC23 WLS WWTR1 ZNF503 Esophagus - Gastroesophageal Junction Male 30-39 Up ADCY5 ANKS1A ANTXR2 ARHGAP10 ARMC9 BTC CACNA1H CACNB2 CALD1 CHRM3 CNTNAP3 CNTNAP3B COL4A5 COL4A6 CYSLTR1 DAAM2 DGKG DHX35 DNAH11 DPYSL3 EML1 EPHA7 ERVFRD-1 FAM83D FBXO30 FGL2 FLNA FOXF2 FOXP1 GPC4 GRPR HDAC9 HIF3A HOXA2 HOXA4 HOXB3 HOXB4 HPSE2 IGSF9B KANK2 KCNMA1 KCNMB1 KCNQ4 KIAA0753 KLHL42 LSM11 MAGEB17 MEIS1 MRGPRF MYH11 MYLK MYOC NKX6-1 NRP2 NTN1 OCRL P2RY14 PALLD PARVA PDZRN3 PGM5 PLEKHO1 PPP1R12A PRDM8 PRUNE2 RBPMS RGMB RGS2 RSPO2 RSPO3 S1PR3 SCUBE1 SELENOM SEMA3A SEMA3E SETD1B SLC2A12 SLITRK3 SMTN SORBS1 STON1 SYNM TACR2 TGFB1I1 TOX2 TTC23 VIPR2 WLS ZHX3 Pancreas Male 30-39 Up AMY1A AMY1C AMY2A AMY2B ANXA4 AQP12A AQP12B BHLHA15 CATSPERB CEL CELA2A CELA2B CELA3A CELA3B CFTR CHST4 CLDN10 CLDN6 CLPS CLPSL1 CLPSL2 CPA1 CPA2 CPB1 CTRB1 CTRB2 CTRC CTRL CUZD1 DCDC2 EPB41L4B ERICH5 ERO1B ERP27 FAM3B FBXW12 FKBP11 G6PC2 GATM GCG GLP1R GNMT GP2 GPR119 GUCA1C HOMER2 IAPP IL22RA1 INS KCNK16 KIRREL2 KLK1 LENG9 LGALS2 LHFPL5 MNX1 NEURL3 NR5A2 ONECUT1 OR10G6 OR2I1P OR4D5 PDIA2 PDX1 PGGHG PKHD1 PLA2G1B PNLIP PNLIPRP1 PNLIPRP2 PRDX4 PRSS1 PRSS2 PRSS3 PTF1A RBPJL REG1A REG1B REG3A REG3G RNF186 SCTR SEL1L SERPINA4 SERPINI2 SLC30A2 SLC30A8 SLC38A5 SLC39A5 SLC43A1 SLC4A4 SPINK1 SYCN TC2N TECPR1 TMED6 TPST2 TRPV6 UBD XBP1 Adipose - Visceral (Omentum) Male 30-39 Up ADAMTS1 ADAMTS4 ADAMTS9 ADIPOQ AGPAT2 AKAP12 APOLD1 AQP7 ARHGEF15 ATP1B3 BDKRB2 BTNL9 C2ORF66 CCDC71L CCL2 CCNL1 CD300LG CD36 CD93 CDC42EP2 CDC42EP4 CDKN1A CH25H CHD1 CIDEA CIDEC CPSF4L CTSL CXCL2 DCUN1D3 DLC1 DUSP6 FABP4 FAM110D FAM89A FASN FOSB FOSL1 GFPT2 GHR GPBAR1 GPIHBP1 GPR4 HAS1 IL10 IL6 ITLN1 KDM6B KIAA0040 LGALS12 LIPA LPL MAFF MAP3K8 MCL1 MEDAG MMP19 MT1A MT1E MT1M MT2A MYC NEURL2 NMB NOCT OR2B11 OR52N1 OR52N5 PIM1 PLAU PNP PNPLA2 PPARG PPP1R15B PRKAR2B PROKR1 PRRT4 RASD1 RDH10 RDH5 SELE SERTAD1 SLC19A2 SLC25A25 SLC25A44 SLC30A1 SLC7A10 SMIM3 SNAI1 SOCS3 SOX17 SOX7 SPAAR SPSB1 THBD TIMP4 TM4SF1 TMEM132C TMEM88 TRIB1 Stomach Male 30-39 Up A4GNT ADAM28 AGR2 AKR7A3 AKR7L AMACR ANXA10 ARL14 ATP4A ATP4B B4GALNT3 BAIAP2L1 BARX1 C9ORF152 CA2 CA9 CAPN13 CAPN8 CAPN9 CCKAR CCKBR CHIA CLDN18 CLIC6 COL2A1 CST11 CTSE CXCL17 CYP2S1 CYSTM1 DAZ1 DAZ4 DGKD EPN3 ESRRB ESRRG FER1L6 FMO5 FOXA2 FOXA3 FOXQ1 FRMD1 FUT1 GALE GCNT4 GHRL GKN1 GKN2 GPR155 GPRC5C KCNE2 LIPF LIPH MCIDAS MECOM MFSD4A MUC1 MUC5AC MUC6 MYH13 MYRF NBPF12 OSBPL7 P2RY14 PALM3 PDILT PGA3 PGA4 PGA5 PGC PIK3C2G PSCA PTGDR2 PXMP2 RASSF6 RFLNA RFX6 S100P SLC26A9 SLC4A2 SLC5A5 SLC9A1 SLC9A2 SLC9A4 SULT1C2 TFF1 TFF2 TMED6 TMEM171 TMEM92 TOX3 TPCN2 TRIM50 TRIM73 TRIM74 VSIG1 VSIG2 VWA2 XYLT2 ZFPM1 Small Intestine - Terminal Ileum Male 30-39 Up ACE ACE2 ACSL5 ADGRG7 ALPI AMN ANKS4B ANPEP ANXA13 AOC1 APOA4 APOBEC1 B3GALT5 BAIAP2L2 BCO1 BTNL3 BTNL8 C17ORF78 CAPN13 CCL25 CCR9 CDHR2 CDHR5 CEACAM18 CEACAM20 CES2 CLDN15 CPO DPEP1 ENPEP ENPP7 ERICH4 FABP2 FABP6 FAM151A FAM177B GBA3 GIMD1 GPR35 GPR82 GUCA2A GUCY2C HKDC1 HNF4G KCNJ13 MALRD1 MEP1A MEP1B MIA2 MISP MOGAT3 MS4A10 MS4A8 MTTP MUC17 MUC3A MYO1A MYO7B MYRFL NAALADL1 NLRP6 OAT P2RY4 PEPD PRAP1 RBP2 REG4 SI SLC10A2 SLC13A1 SLC13A2 SLC15A1 SLC17A8 SLC23A1 SLC23A3 SLC28A2 SLC39A4 SLC3A1 SLC51B SLC5A1 SLC5A12 SLC5A9 SLC6A19 SLC6A20 SLC7A9 SMIM24 SOAT2 SPINK4 SULT1C3 TAS2R38 TM4SF20 TM6SF2 TMEM150B TMEM236 TMEM253 TMIGD1 TREH TUBAL3 VIL1 XPNPEP2 Colon - Transverse Male 30-39 Up AHCYL2 AOC1 AQP8 ATOH1 B4GALNT2 BCL2L15 BEST4 C15ORF48 CA1 CA2 CA7 CALML4 CASP6 CCL15 CDH17 CDX1 CDX2 CEACAM1 CEACAM5 CEACAM7 CES3 CLDN3 CLDN7 CLRN3 DHRS11 DQX1 EFNA2 ENTPD8 EPCAM EPS8L3 ERN2 ETHE1 FABP1 FAM83E FCGBP FXYD3 FZD5 GAL3ST2 GCNT3 GPA33 GPR35 GUCY2C HEPACAM2 HHLA2 HOXB9 HSD11B2 HTR3E IHH ISX KRT20 KRT8 LGALS4 LRRC19 LRRC31 LYPD8 MARVELD3 MIER3 MISP MOGAT3 MS4A12 MTMR11 MUC12 MUC13 NOX1 NXPE1 NXPE2 NXPE4 OTOP2 PHGR1 PIGR PIGZ PLA2G10 PLS1 PPP1R14D PRELID2 PRR15 RXFP4 SATB2 SELENBP1 SLC26A2 SLC26A3 SLC44A4 SLC9A2 SLC9A3 SMIM22 ST6GALNAC1 TMEM236 TMEM54 TRIM31 TRPM4 TRPM6 TSPAN1 TSPAN8 TST TUBAL3 UGT1A10 UGT1A8 UGT2B17 URAD ZG16 Colon - Sigmoid Male 30-39 Up ABL1 ACTG2 ANKFY1 ATP2B4 BAG2 BMP3 BTC C3ORF80 CAB39L CACNA1C CACNA1H CCL11 CDK8 CHRM2 CNN1 COL24A1 CSRP1 EML1 EPHA7 FBXL22 FOXF1 FOXP2 FXYD6 FZD7 GDNF GJC1 GLB1L2 GLP2R GREM2 HAND1 HAND2 HDAC4 HEPH HOXA13 HOXB3 HOXD10 HOXD11 HOXD12 HOXD13 INAFM2 KCNMA1 KCNQ4 KIZ KLHL23 LBR LIMS2 LRCH2 LRIG1 LRRC3 MAB21L2 MASP1 MDM1 METTL24 MID1 MRGPRD MRGPRF MYH11 MYLK MYOCD NKX2-3 NKX3-2 NPY4R NRP2 NT5DC3 NTSR1 NXN PDE3B PDE9A PDZRN3 PDZRN4 PGM5 PHOX2B PLA2G2C PLEKHO1 PLXNB3 PNCK PPP1R12B PTBP2 PTCHD1 PTGFRN PTGS1 QRFP RAB23 RNF150 ROR2 SEMA3A SMTN SPOP STON1 STON1-GTF2A1L SYDE2 TACR2 TBC1D1 TEAD3 TES TMEM252 TMTC2 TNFAIP8L1 TSPAN2 UBXN10 Skin - Not Sun Exposed (Suprapubic) Male 30-39 Up AADACL2 ABCA12 ABHD12B ACAD9 ACER1 ACSM6 ADGRF4 AHNAK2 AIPL1 ARHGEF19 ATP6V1C2 BLMH BNIPL BPIFC C1ORF74 CALML5 CARD18 CASP14 CCL27 CDHR1 CDX4 CERS3 CLDN1 COL17A1 COL7A1 CPA4 CRX CST6 DCD DCT DEGS1 DMKN DSC3 EFNA3 ELOVL3 FAM83C GAN GJB3 GJB4 GNAT1 GNGT1 HR IFFO2 IL20RA IL20RB IRX3 IRX4 KCNJ18 KCNK7 KLC3 KLF4 KRT1 KRT14 KRT77 KRT79 KRT80 KRT84 KRTAP20-2 KRTDAP LAMB4 LGALS7B LGALSL LIPK LIPM LRIT2 LY6G6C LYPD6B MFSD2A MLANA NIPAL4 NKPD1 PARD6G PKP1 PLA2G2F PLA2G4F PNLIPRP3 POU2F3 PPP1R14C RBP3 RHO RORA SDC1 SDR42E1 SERPINB5 SPINT3 SPTLC3 SPTSSB TAS1R2 TET3 TFAP2A THEM5 TMEM254 TMEM45A TNFRSF18 TNFRSF19 TNS4 TYR WFDC5 WNT16 ZNF273 Prostate Male 30-39 Up ALOX15B AMD1 ANO7 ARG2 ARTN BMPR1B C1QTNF9B CBFA2T2 CDH26 CFAP69 CHRNA2 COL9A1 CPA6 CPAMD8 CPLX3 CPNE4 CREB3L4 CUX2 DLK2 DMXL1 EBF4 EFCAB12 ELK4 EVX1 FAAH FBXL8 FEV FOLH1 FOXA1 GATA2 GCNT2 GLB1L2 GLIS1 HOXA13 HOXB13 ISL1 KCNH6 KLK2 KLK3 KLK4 LMAN1L LPAR3 MESP1 MLPH MSMB NEDD4L NEFH NKX3-1 NPY NTF4 OR51C1P OR51D1 OR51E2 OR52R1 PAGE4 PAK1IP1 PDE11A PLPP5 PNPLA7 POTEG POTEH POTEM PRAC1 PRAC2 PRDM8 RABEP2 RCAN3 RDH11 RFPL1 RFPL2 RLN1 SERPINB11 SHROOM1 SLC15A2 SLC30A4 SLC45A3 SORD SP8 SPDEF SRD5A2 STEAP2 TESK2 TGM4 TMCO4 TMEM141 TMPRSS2 TRPM8 TRPV6 TTC6 UPK3A USP43 WNK4 XKR5 ZNF350 ZNF613 ZNF761 ZNF813 ZNF816 ZNF827 ZNF888 Breast - Mammary Tissue Male 30-39 Up ACOT4 ADAMTS15 ADAMTS3 ADCY4 ADGRL4 ADIPOQ ADRA2A AIFM2 ANGPT4 ANKRD30A AQP7 ARHGAP40 ARHGEF15 ASB13 AVPR2 AZGP1 BTNL9 CD300LG CD36 CIDEC CRACR2B CST9 CYYR1 DPT DUSP4 ELMOD3 ELOVL5 ESR1 FABP4 FAM124B FGF10 FOXA1 FZD4 GALNT6 GFRA1 GNG11 GPD1 GPIHBP1 GPR146 GREB1L GSC HCAR1 HOXB7 INPP4B IRX5 ITIH5 KIF12 KLHDC7A LGALS12 LIFR LIPE LMX1B MYB NLRP13 NLRP8 NPY2R NXNL1 PALMD PAPPA2 PEMT PI15 PLIN1 PLIN4 PNPLA2 PPARG PRLR PROKR1 RAB6C RAI2 RAMP2 RDH5 RNF125 SCGB2A2 SCRN2 SEC14L2 SEMA3G SGK3 SMIM3 ST8SIA6 STC2 SYNE3 TACR1 TBC1D9 TFAP2B TIMP4 TMEM132C TMEM26 TNN TRPS1 TTC6 USHBP1 VKORC1L1 VTCN1 XBP1 ZBED3 ZNF689 ZNF792 ZNF92 Testis Male 30-39 Up ACSM4 ANKRD31 ANKRD60 ARGFX ASZ1 BEND2 C12ORF40 C18ORF63 C19ORF84 CCDC172 CCDC73 CCNB3 CDC14C CRYGC DAZL DCAF12L1 DCAF4L1 DCAF4L2 DCAF8L1 DCAF8L2 DDX4 DDX43 DMRT1 DMRTB1 DMRTC2 DNAH8 DNAJC5G EPPIN ESX1 EXD1 FATE1 FBXO47 FOXR2 FSHR GSC2 HORMAD1 HORMAD2 HSF2BP KCNK13 KIAA1210 KIF4B LDHAL6B LRRC71 LUZP4 MAGEA10 MAGEA3 MAGEA6 MAGEB1 MAGEB2 MAGEB3 MAGEC1 MAGEC2 MAJIN MORC1 MOV10L1 MROH2B NLRP4 NUP210L PIWIL1 PIWIL2 POM121L2 PRDM14 PRND PRR23A RAD21L1 RAD51AP2 RAD9B RBM44 RBM46 RFPL4B RHOXF2 RNF17 SLC25A31 SMC1B SPATA22 SPO11 STK31 SYCP1 SYCP3 SYNGR4 TAF1L TAF7L TDRD1 TDRD15 TDRD5 TERB1 TERB2 TEX12 TEX14 TFDP3 TKTL1 TKTL2 TOPAZ1 TPTE TRIM60 TRPC5OS TSPYL6 TUBA3C ZNF728 ZNF99 Minor Salivary Gland Male 30-39 Up AGFG2 AMTN ANKRD36C APCDD1L ASCL3 AZGP1 BACE2 BIK BPIFB2 C4ORF19 C6ORF58 CCDC160 CCL28 CEP41 CES5A CHPT1 CHST9 CLDN10 CRACR2A CRACR2B CRISP3 CYP4X1 DEFB1 DNASE2B EHF ELF5 ENPP3 ENTPD3 FAM3D FBN3 FDCSP FUT2 GALNT4 GALNT6 GCNT3 GDF5 GLYATL2 GPRC6A HTR3A KCNN4 KRT23 KRT7 LPO LRRC26 LTF LYZ MANSC1 MGAM2 MLPH MMP7 MPV17L MUC16 MUC19 MUC5B MUC7 NAALADL2 NKX2-6 NXPE2 ODAM OTX1 PANX3 PHLDA1 PIGR PIP PLEKHS1 PLPP2 PROM1 PRR27 PRR4 PRSS8 RAD51B RHCE RHD RNASE8 SH3BP4 SLC28A3 SLC31A2 SLC37A2 SLC6A14 SLFN13 SLITRK6 SLPI SMR3A SPDEF STATH STK39 SVOPL TCN1 TMC5 TMED3 TMEM200C TMEM63A TNFRSF11A TNFSF15 TRPV4 WFDC2 WWC1 ZG16B ZNF552 ZSWIM4 Muscle - Skeletal Male 30-39 Up ADSL ALDOA ANKRD23 ART1 ASB12 ASB2 ASB5 ASB8 BIN1 C19ORF47 CACNB1 CACNG1 CACNG6 CAND2 CHRNA1 CHRNB1 CHRND CKM CMYA5 COQ8A CSDE1 CYB5R1 DCAF6 DUSP13 EEF1A2 ENO3 EYA4 FEM1A FHL3 JPH1 JSRP1 KCNA7 KCNJ11 KIF1C KLHL41 LBX1 LMOD3 LRRC2 LRRC30 MACROD1 MAFA MAPK12 MYBPC1 MYBPC2 MYH1 MYO18A MYO18B MYPN NEB NFE2L1 NRAP OBSCN OPTN P2RX6 PDE4DIP PFKM PGM1 PGPEP1L PHKA1 PHKG1 PLCD4 POPDC3 PPP1R27 PRKAG3 PROB1 PYGM RAD23A RAPSN RNF123 RPUSD4 RTN2 RYR1 SCN4A SH3BGR SIX1 SIX4 SMTNL2 SPTB STAC3 SYPL2 TCEA3 TEAD4 TMEM233 TMEM38A TMOD4 TNNC2 TNNI2 TNNT3 TRDN TRIM54 TRIM63 TRIM72 TTN UBE2D4 UBR3 UCP3 USP13 USP38 UTP11 YBX3 Artery - Tibial Male 30-39 Up ACTA2 ACTN4 ADARB1 ADIRF ALDH1B1 AMIGO2 ARHGEF39 ATL3 AVPR1A BCAM C11ORF96 C12ORF75 C1QTNF7 CDH6 CHSY3 CLIC4 CNTN4 COL14A1 COL18A1 CPED1 CRLF1 CRTC3 CSPG4 CSRP2 DACT3 DSTN EFHD1 ESD FHL5 FOXC1 FOXC2 FOXL1 FRY GADD45G GJA4 HES4 HEY2 HOXC11 HRCT1 HTR1B ID2 IGFBP7 INHBA ITGA5 ITPR1 JAG1 JAK2 KCNA5 KCNAB1 KCTD10 KLHL26 LMOD1 LPP MAP7D3 MCAM MSRB3 MUSTN1 MYL9 MYO1D NKD1 NOTCH3 NTF3 NTRK3 P2RX1 PACSIN2 PDK3 PLEKHG3 PLS3 PMEPA1 PPP1R14A PRELP PRKG1 RASL12 RASSF3 RCAN2 RHOB RNF180 ROCK1 ROR1 RRAS SDK1 SELENOM SH3BGRL SMIM10 SORBS2 SPOPL SUSD5 TAGLN TASP1 TBX18 TBXA2R TGM2 TLN1 TMEM181 TNC TNS1 TRABD2B UBA2 WTIP ZFHX3 Nerve - Tibial Male 30-39 Up AATK ABCA8 AFAP1L2 ANGPTL7 APOD ARHGAP19 ARHGAP39 ARHGEF10 BIRC7 BMP8B CADM4 CASKIN2 CDH19 CLCN2 CLDN19 CLDN20 CNTF COL28A1 DCLK3 DHH DRP2 EBF2 EGFL8 EGR2 EHBP1 EMILIN3 ENTPD2 EPB41L2 EXTL1 FGF4 FGFBP2 FIGN FMNL3 FOXD1 FOXD2 FOXD3 GAL3ST1 GAS2L3 GJC3 GLI1 HSPA12A IGFBP6 IL17B IL9 INF2 ITGA6 ITGB8 KANK4 KCNK12 KIF19 LCTL LGI2 LGI4 MAPK8IP1 MIA MICALL2 MPZ NCMAP NEK1 NGFR NRIP2 OR6B2 OR6B3 OTUD7B PAPLN PLEKHA4 PLLP PMP22 PRICKLE1 PRIMA1 PRRG3 PRX PTPDC1 PTPRU RTKN SBSPON SECISBP2L SEMA3B SEMA4C SEMA5A SFRP5 SH3TC2 SHC4 SHH SLC25A48 SLC2A1 SMCO3 SORCS1 SPTBN5 ST6GALNAC2 THSD7A TLDC2 TMEM215 TMPRSS5 TXNL4B USP53 VIT VWA1 WNT6 ZDHHC8 Skin - Sun Exposed (Lower Leg) Male 30-39 Up AADACL2 ABCA12 ABHD12B ACER1 ADGRF2 ADGRF4 ALOX12B ALOXE3 ANKRD35 ANXA9 ASPRV1 ATP13A5 ATP6V1C2 BPIFC C1ORF68 CALML5 CASP14 CDSN CTNNBIP1 CYP4F22 DCD DEGS2 DLX3 DMKN DSC1 DSG1 EFNA3 EFNA4 EPHB3 EPHX3 FAM110A FAM83C FAM83G FLG FLG2 FOXN1 GAN GJB3 GSDMA HELT HOXC12 HS3ST6 IDE IFFO2 IL17RE IL36B IL36RN KCNK7 KLC3 KLK5 KLK7 KPRP KRT10 KRT2 KRT23 KRT80 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE4A LCE6A LIPM LY6G6C LYPD5 NKPD1 NLRP10 PKP1 PLA2G2F PLA2G4E PLA2G4F PNLIPRP3 PNPLA1 POF1B PSAPL1 RDH12 SAPCD1 SBSN SDR42E1 SDR9C7 SERPINA12 SERPINB12 SLC46A2 TGM5 THEM5 TINCR TMEM45A TMEM86A TMPRSS13 TREX2 TUFT1 UNC93A WFDC5 XKRX Adipose - Subcutaneous Male 30-39 Up ACER2 ACVR1C ADAMTS5 ADGRF5 ADGRL4 ADH1B ADIPOQ ADRA2A AFAP1L1 AGTR1 AIFM2 ANGPT4 APOL3 APOLD1 AQP7 ARHGAP20 ARHGEF15 ATP8B4 AVPR2 BMP6 C19ORF12 CD300LG CD34 CD36 CFD CIDEA CIDEC CLEC3B COL5A3 CPM CYYR1 DOCK11 EBF1 EBF3 ELMOD3 FABP4 FAM124B FGD5 FZD4 GALNT15 GFRAL GHR GPD1 GPIHBP1 GPR146 GSN HEBP2 HTR1F INHBB ITGB1BP1 ITIH5 KCTD12 KLB KRTAP13-4 LEP LHX6 LIPE LRRC8C LVRN MAN1A1 MEOX1 MMRN2 MOCS1 NMT2 NXNL1 OPN4 PDE3B PECAM1 PLIN1 PLIN4 PLXNA4 PNPLA2 PPARG PRKAR2B PTPRM RAMP2 REM1 RNF125 S1PR1 SASH1 SEMA3G SIK2 SLC19A3 SMIM3 SRPX2 STAT5A STEAP4 SYNE3 TACR1 TIE1 TIMP3 TIMP4 TLN2 TMEM132C USHBP1 UVRAG VKORC1L1 VWF ZBED3 ZNF366 Brain - Substantia Nigra Male 60-69 Up ADARB2 ANKRD40 BAALC BCAS1 C10ORF90 C1ORF122 CA14 CARNS1 CCDC160 CCDC163 CDK18 CERS1 CHRNB3 CHST6 CLDND1 CLEC19A CNDP1 CNP CNTN2 CNTNAP4 COL9A2 CTNNA3 DBNDD2 DBX2 DNER DOHH ENHO ERMN FAM181B FEZ1 FGF1 FOXB1 GCSH GFAP GLRA1 GPR62 HAPLN2 HIPK2 ITPKB KCNE5 KCNG4 KCNJ10 KCNJ6 KIF6 KLHL1 KLHL32 LACC1 LHPP LRRC55 LUZP2 MAG MBP MOBP MOG MTURN NIPA1 NKX6-2 NTSR2 OC90 OLIG1 OLIG2 PAAF1 PAIP2B PAQR6 PEX5L PIP4K2A PIRT PKP4 PLEKHB1 PMP2 PRR18 PSRC1 QDPR RET RFTN2 RND2 ROM1 RPE65 S100B SHTN1 SLAIN1 SLC10A4 SLC15A5 SLC18A2 SLC5A11 SLC6A11 SLC6A3 SLCO1A2 SPOCK3 SPX SYNJ2 TMEM144 TMEM229A TMEM235 TMEM255A TMEM88B TP53INP2 TRIL TRIM41 TSC22D4 Kidney - Cortex Male 60-69 Up ACMSD ACY1 ACY3 AGMAT AGXT2 AQP2 AQP6 ATP6V0A4 ATP6V0D2 ATP6V1B1 ATP6V1G3 BBOX1 BSND C11ORF54 CDH16 CLCNKB CLDN16 CLDN2 CLEC18A CLEC18B CLEC18C CUBN CYP24A1 CYP27B1 CYS1 DCDC2 DDC DMRT2 DUSP9 EMX1 FCAMR FMO1 FOXI1 FXYD2 FXYD4 GGT1 GLYAT HNF1B HOXB6 IL17RB KCNJ1 KCP KL LRP2 LY6L LYG1 MCCD1 MIOX NAT8 NPHS1 NPHS2 OGDHL OR2T10 PAX2 PDZK1 PDZK1IP1 PKHD1 PODXL PRODH2 PTH1R RBP5 RHBG SLC12A3 SLC13A1 SLC13A3 SLC16A4 SLC17A1 SLC17A3 SLC22A11 SLC22A12 SLC22A13 SLC22A2 SLC22A24 SLC22A6 SLC22A8 SLC34A1 SLC34A3 SLC3A1 SLC47A2 SLC4A9 SLC5A10 SLC5A12 SLC5A2 SLC6A13 SLC6A18 SPP1 TINAG TMEM174 TMEM207 TMEM213 TMEM252 TMEM52B TMEM72 TRPV5 UGT1A9 UGT2B7 UGT3A1 UNC5CL UPP2 ZPLD1 Brain - Anterior Cingulate Cortex (BA24) Male 60-69 Up ADCY2 APC ARL6IP1 ASIC2 BRSK1 BTBD2 C1QL3 C2CD4C CA11 CACNG5 CAMK2A CAMK2N1 CASKIN1 CCK CREG2 CSPG5 CTNNA2 CTNND2 DEAF1 DGKZ DLX1 DOK6 DRD5 ELFN2 ERC2 FAM107A FAM163B FAM81A FBXO41 FEZF2 FOXG1 FXYD7 GABRA2 GABRA3 GAD1 GAP43 GPM6A GRIN3A HSD11B1L IDS JPH3 KCNC2 KCNN1 KCTD16 KIF1A KIF5A LHX2 LIMK1 LMO4 MAP1A MAP2 MAP3K10 MAPK8IP2 MCF2L2 MEIS3 MPPED1 MYRIP NANOS3 NCAN NCS1 NPTXR NR2E1 NRG3 NRSN1 NSMF NTRK2 OLFM1 OSTN PACSIN1 PALM PHF24 PLPPR5 PTER RAB6B RAPGEF4 RNF182 RUNDC3A SCG3 SERPINI1 SFXN5 SHANK1 SHC3 SLC17A7 SLC25A18 SLC35F1 SLC39A12 SLC6A1 SMIM10L2A SNCB SNPH STOX1 STUM SYN1 SYN2 SYT17 TAGLN3 TFPT TNR TSPOAP1 WSB2 Brain - Hippocampus Female 60-69 Up ABCA2 ABCG2 ADARB2 AMER2 ANKRD40 ANO4 ASPA B3GAT1 B3GAT2 BCAN BDNF C10ORF90 C1QL2 C1QTNF9B CABP7 CACNG8 CCP110 CDK19 CERCAM CNDP1 CNIH2 CNP CNTN2 CRB2 CSAG1 DBNDD2 DSCAM DYNC1LI2 ERMN FAM107A FEZF2 FGF1 FRMD5 GOLGA7 GPM6B GPR37 GPR62 GPRC5B HHIP HIPK2 HRK IFIT2 IL1RAPL1 KCNN1 KIF6 KLHL2 KLHL32 LHFPL3 LPAR1 MAP4K4 MAS1 MFRP MKRN3 MTURN MYRF NCAM2 NEUROD6 NEUROG3 NKAIN2 NKX6-2 NOX3 NPTXR NSMF OLIG1 OLIG2 OPALIN P2RX7 PAIP2B PCDH15 PCDH20 PCDH9 PDE6B PEX5L PHACTR3 PHLPP1 PIP4K2A PLPPR1 POU3F3 PPM1E PRR18 PSRC1 PTPRZ1 QDPR RAPGEF4 RFTN2 SCART1 SHISA6 SHTN1 SLAIN1 SLCO1A2 SOX8 SPOCK3 TMEFF1 TMEM144 TMEM235 TMEM88B TNR TRIM2 TTYH2 ZNF488 Brain - Anterior Cingulate Cortex (BA24) Female 60-69 Up ADAP1 ADCY2 ADCYAP1R1 ADGRB1 AIFM3 ALDOC AMELX ARHGDIG ASIC2 BCAN BRINP2 C1QL2 C2CD4C CACNG5 CAMK2A CAMK2N1 CCK COL20A1 CRB1 CSAG1 CSPG5 CTNNA2 CTNND2 CXCL11 DBX2 DDAH1 DEAF1 DRD5 ELFN2 FABP7 FAM107A FAM171B FAM181B FEZF2 FOXG1 FXYD7 GABRA2 GABRA3 GAREM2 GPM6A HEPACAM HES5 HHIPL1 HSD11B1L IDS KCNC2 KCNN1 KIF1A KIF5A LHFPL3 LHX2 LRRC3B LY6H MAPK8IP2 MCF2L2 MEIS3 MLC1 MPPED1 MT3 MYRIP NANOS3 NCAN NCS1 NKAIN3 NKAIN4 NPAS3 NR2E1 NRG3 NSMF NTRK2 NWD1 OLFM2 PALM PHACTR3 PTER PTN PTPRZ1 RAPGEF4 RGR RNF182 RNF208 SCG3 SFXN5 SHANK1 SHC3 SLC1A2 SLC1A3 SLC25A18 SLC35F1 SLC39A12 SLC6A1 SLCO1C1 SNCB SNPH STOX1 SYN1 SYT17 TFPT TNR TTYH1 Brain - Caudate (Basal Ganglia) Female 60-69 Up ACBD7 ACSBG1 ADCYAP1R1 ADORA2A AHCYL1 ALDH7A1 ANKRD34B ANO3 AQP4 ATP1B2 BAALC BCAN CABLES1 CACNG4 CDH20 CHAT CORT CPE CRB2 CSAG1 CYP46A1 DACT2 DDAH1 DLX6 DRD1 ENHO ETNPPL FAM171B GABRA2 GABRB1 GABRG1 GAREM2 GLUD1 GNG7 GPC5 GPR143 GPR37L1 GPR88 GRM3 HEPACAM HHIPL1 HPCA HS3ST5 IL17D IQCA1 KCNH4 KCNK18 KCTD17 LGI1 LIX1 LRP4 LRRC10B LRTM2 LYPD1 MAPK4 MC4R MEGF10 METRN MLC1 MRO MT3 NDP NKAIN3 NPAS3 NR2E1 NTRK2 NTSR2 ONECUT2 PCP4 PDE1B PITPNC1 PON2 POU3F4 PPP1R1B PPP3CA PSD2 PTPN5 PTPRZ1 RANBP3L RASD2 RGS14 RGS20 RGS9 RLBP1 SCN4B SFXN5 SIX3 SLC1A2 SLC1A3 SLC25A18 SLC25A23 SLCO1C1 SNN SOX2 STON2 SYNDIG1L TNIK TP53BP2 TRIL TTYH1 Brain - Nucleus Accumbens (Basal Ganglia) Female 60-69 Up ADCYAP1R1 AHCYL1 AKAP5 ANKRD34B ANKRD63 AQP4 ARPP21 C4ORF50 CABLES1 CACNA1E CACNG4 CAMKV CDH4 CNMD COCH CPNE5 CTXN1 CYP46A1 DACT2 DLL3 DRD1 DRD3 DTNBP1 EFNB3 ETNPPL FAT3 GABRA4 GABRA5 GABRB1 GABRG1 GAD2 GLUD1 GNAL GNG7 GPC5 GPR101 GPR143 GPR149 GPR27 GPR52 GPR6 HRH3 HTR1D HTR2C HTR6 IDNK IMPG1 KCNA4 KCNH4 KCNIP1 KCNK18 KCTD4 KIRREL3 KISS1 LAMP5 LHFPL1 LIX1 LRRC7 LRRTM1 LYPD1 MAPK4 MLC1 NCDN NECAB2 NKAIN4 NPAS3 NR2E1 NTSR2 OPRK1 OTOF PCDH11X PDYN PIANP PLPPR1 POU3F4 PRKCG PTPN5 RESP18 RGS20 RGS8 RPRML SH2D5 SHISA7 SIX3 SLC32A1 SLC9A6 SLC9A7 SOWAHA SOX11 STON2 SV2C SYNPR TAC3 THRA TMEM158 TTYH1 TUBB2B VAX1 WNT1 WNT10B Brain - Putamen (Basal Ganglia) Female 60-69 Up ADORA2A AMER2 ANKRD40 ANO3 ASPHD1 ATP1B2 BAALC BCAN CABLES1 CACNG4 CDH20 CERCAM CERS1 CHAT CNDP1 CORT CSAG1 CTNND2 CTXN1 CYP46A1 DACT2 DRD2 ENHO ETNPPL FAM107A FAM181B FGF1 FOXO4 GBX2 GNG7 GPC5 GPR143 GPR37L1 GPR6 GPR85 GPR88 GPRC5B GRM3 HCN2 HDAC11 HEPACAM HIPK2 HPCA HRH3 HS3ST5 IFNA6 ITPKB KCNH4 KCNJ10 KCTD17 LPAR1 LRRC10B LRTM2 MAP4K4 MAPK4 MEGF10 METRN MLC1 MT3 MTURN NKX6-2 NTSR2 OLIG1 OLIG2 OPALIN PCP4 PDE1B PHACTR3 PHLPP1 PIP4K2A PLEKHB1 PPP1R1B PRR18 PSD2 PTPN5 QDPR RAB11FIP4 RASD2 RGS20 RGS9 RLBP1 ROM1 SCN4B SFXN5 SHTN1 SLC18A3 SLC1A2 SLC24A2 SLC25A18 SLC39A12 SLC6A12 SLCO1A2 SOX8 SPOCK3 STON2 SYNDIG1L TMEM235 TRIL TSC22D4 TTYH1 Liver Female 60-69 Up A1BG A1CF ABCB11 ABCC2 ABCG5 ABCG8 ACOT12 ACSM5 AFM AGT AGXT ALDH8A1 AMBP ANGPTL3 APOA1 APOA2 APOC1 APOC2 APOC3 APOC4 ASGR1 ASGR2 ATF5 BAAT C4BPB C8A C8B C8G CCL16 CLDN14 COLEC10 CPB2 CPN2 CYP2D6 CYP4F3 CYP8B1 DECR2 DHODH F12 F2 F7 F9 FGF21 FTCD GCGR GCKR GDF2 GLTPD2 GOLT1A GYS2 HABP2 HAO1 HGFAC HP HPD HPN HPX IGFBP1 INHBC ITIH1 ITIH3 ITIH4 KLKB1 LEAP2 MASP2 MAT1A MST1 NR1I3 ORM1 ORM2 PAH PCK1 PIPOX PLGLB2 PROC PROZ PZP SAA4 SARDH SDS SERPINA11 SERPINA6 SERPINC1 SERPINF2 SLC13A5 SLC17A2 SLC22A1 SLC22A25 SLC22A9 SLC25A47 SLC28A1 SLC38A4 SPP2 TAT TDO2 TFR2 THPO TM4SF5 UPB1 VTN Cells - EBV-transformed Lymphocytes Female 50-59 Up AICDA ANGPTL6 APOBEC3G ATAD5 B3GNT2 BATF BLNK BTK BTLA C17ORF99 CCL22 CCNI2 CCR7 CD226 CD40 CD48 CD70 CD79A CD80 CD86 CENPM CLEC17A CLEC2D CLNK CPOX EAF2 EBI3 ETV3L FAM111B FAM72B FAM72C FAM72D FCER2 FCRLA FSBP GCSAM GNGT2 GPR15 GPR55 HELLS HLA-DQA2 IFI44L IFIH1 IKZF2 IKZF3 IL12RB2 IL21R IRF4 IRF5 ITGB7 LGALS14 LTA LY75 MACC1 MCM2 MCOLN2 MX1 MYBL2 MYL12BP2 NFKBIE NUP210 OAS2 OAS3 P2RY10 PAX5 PIF1 PIK3R6 PIM2 PMAIP1 POU2AF1 POU2F2 RAD54B SEMA7A SLAMF1 SLAMF7 SPIB SPN STAP1 STAT1 TCL1A TEC TIFA TLR10 TLR7 TMPRSS3 TMSB15B TNF TNFRSF13B TNFRSF17 TNFRSF8 TNFSF9 TRAF1 TSPAN33 TTF2 USP18 VASH2 WDFY4 WNT10A ZC3H12D ZNF318 Lung Female 50-59 Up A2M ABCA3 ACOXL ACP5 ACVRL1 ADAMTS8 ADGRF5 ADGRL2 AGER ALDH3B1 ANOS1 ATP11A BMP5 C11ORF16 CACNA2D2 CALCRL CASS4 CCDC102B CCDC17 CCL18 CEACAM6 COL6A5 COL6A6 COX4I2 CROCC2 DRAM1 EMP2 EPAS1 FCN3 FGFR4 FLRT3 FOLR1 GALNT18 GBP4 GGTLC1 GPRC5A HECW2 HTR3C ICAM1 IDO1 IL15RA IL1RL1 IL7R INMT LAMC3 LAMP3 LPCAT1 LRRN4 LTK MARCO MS4A15 MSR1 NAPSA NCKAP5 NDNF NKD2 ODF3B OLR1 OR6K3 OR6N2 PCDH12 PHEX PODXL RAMP3 RBMS2 RGCC ROS1 RP1 RS1 RSPO4 RTKN2 SCGB1A1 SCGB3A2 SFTA2 SFTPA1 SFTPA2 SFTPB SFTPC SFTPD SHROOM4 SLC34A2 SLC39A8 SLC6A4 SLCO2A1 SLCO4A1 SMAD6 STARD8 TBX2 TBX4 TCF21 TEK TFEC TFPI TMEM100 TMEM125 TSPAN19 VEGFD VIPR1 WNT2 WNT3A Pancreas Female 50-59 Up AKR7A3 AMY1A AMY1B AMY1C AMY2A AMY2B ANXA4 AQP12A AQP12B AQP8 BHLHA15 CEACAM16 CEL CELA2A CELA2B CELA3A CELA3B CFTR CHST4 CLDN10 CLPS CLPSL1 CLPSL2 CPA1 CPA2 CPB1 CTRB1 CTRB2 CTRC CTRL CUZD1 EPB41L4B ERICH5 ERO1B ERP27 FAM3B FBXW12 FKBP11 FUT1 G6PC2 GATM GCG GLP1R GNMT GP2 GPHA2 GPR119 GPR150 GRPR GUCA1C HOMER2 IAPP IL22RA1 INS KCNK16 KIRREL2 KLK1 LENG9 LGALS2 LHFPL5 MNX1 NR5A2 ONECUT1 OR10G4 OR10G6 OR4D5 OR6M1 OR8D4 PDIA2 PDX1 PGGHG PKHD1 PLA2G1B PNLIP PNLIPRP1 PNLIPRP2 PRDX4 PRSS1 PRSS2 PRSS3 PTF1A RBPJL REG1A RNF186 SCTR SEL1L SERPINI2 SLC16A12 SLC30A2 SLC30A8 SLC38A5 SLC39A5 SLC43A1 SLC4A4 SPINK1 SYCN TECPR1 TMED6 TMEM97 TPST2 Artery - Aorta Female 50-59 Up ACAN ADRA1B AEBP1 ANO1 ANTXR1 ASPN BGN C1QTNF2 C1QTNF8 CD151 CDH13 CNTN4 COL14A1 COL21A1 COL8A1 COL8A2 CPXM2 CRISPLD1 EFEMP1 ELN EXT1 FAM180A FBLIM1 FBLN5 FGL2 FMOD FOXC1 FRZB GABRR1 GAS6 GDF7 GLIPR1 HAPLN1 HAPLN3 HAUS7 HMCN1 IGFBP2 IGFBP7 ITGA10 ITGA11 ITGA8 ITGB5 KALRN KCNK15 KCNK17 LDOC1 LGR6 LIMS3 LIMS4 LOXL1 LTBP1 LTBP2 LTBP3 MEGF6 MFGE8 MGP MRAP2 MYH10 MYH9 MYO1D NAV1 NAV2 NOX4 NPR1 NXPH3 OGN OMD PCDH7 PCDHB11 PDGFA PID1 PKD2 PLD5 PLS3 PMEPA1 PRDM16 PRDM6 PRKG1 PROS1 PTGIR PTGIS PXDC1 SCUBE3 SMOC2 SOD3 ST6GAL2 STAC STK38L SUGCT SULF1 SUSD5 TBXA2R THBS2 THSD7B TMEM47 TNFRSF11B TPH1 VCAN WWP2 ZNF385D Heart - Left Ventricle Female 50-59 Up ACO2 ACTC1 ASB18 B3GALT2 BCO2 BSG BZW2 CASQ2 CCDC141 CDH2 CHCHD10 CKMT2 COQ10A COX5A COX7A1 COX7B CPT1B CRYAB CSDC2 CSRP3 DAND5 DDO DECR1 EIF1B ETFDH FABP3 FBXO40 FGF18 FHL2 FHOD3 FITM2 GJA3 GOT1 HADHB HHATL HRC HSPB3 HSPB7 ITGB1BP2 KLHL31 KLHL7 LDHB LRRC10 LSMEM2 MAPKAPK3 MDH1 MFN2 MLYCD MPC1 MT1HL1 MTUS2 MYBPC3 MYH7 MYH7B MYL2 MYL3 MYLK3 MYOM2 MYOZ2 MYZAP NDUFA1 NDUFAB1 NEBL NKX2-5 OGDH OXCT1 PDE1C PDHA1 PKP2 PLCXD3 PLN POPDC2 PPM1K PXDNL RBM20 RD3L RYR2 S100A1 SCN5A SDHA SGCG SLC16A7 SLC25A30 SLC25A4 SLC41A1 SLC4A3 SLC8A1 SMCO1 SMPX SMYD2 TCF15 TECRL TENM2 TMEM182 TNNI3 TNNI3K TNNT2 TPM1 UNC45B UQCRC1 Artery - Coronary Female 50-59 Up AEBP1 ANTXR1 ARL4AP5 ART4 ASPN BGN C1QTNF1 CCDC3 CFH CMKLR1 COL18A1 COL4A1 COL4A4 CPXM2 CRIP1 CSRP2 EFEMP1 FBLIM1 FMOD FOXS1 FRK HAPLN1 HEYL IGFBP7 IL33 ITGB5 IZUMO1R JADE1 KCNA5 KCNT2 LGR6 LRRC17 MAP3K7CL MEGF6 MFAP4 MSC MTHFD1L NTF3 OGN OMD PCOLCE2 PLA2G2A PLAC9 PPP1R14A PTGIS SPINK13 ST6GAL2 TBX18 TBXA2R TGM2 THBS2 TIMP1 TNFRSF11B TRABD2B VCAN WFDC1 Small Intestine - Terminal Ileum Female 50-59 Up ACSL5 ADGRG7 AKR7L ALPI AMN ANPEP ANXA13 APOA4 APOBEC1 BAIAP2L2 BTNL3 BTNL8 C11ORF86 C17ORF78 CCL25 CCR9 CDHR2 CDHR5 CEACAM18 CEACAM20 CHST5 CLCA1 CLDN15 CLDN2 CPO DEFA5 DEFA6 DGAT1 DMBT1 DPEP1 ENPEP EPS8L3 ERICH4 FABP2 FAM151A FAM177B FGF19 GBA3 GPR152 GUCA2A GUCA2B GUCY2C HKDC1 HNF4G ITLN2 KCNJ13 MALRD1 MEP1A MEP1B MISP MOGAT3 MS4A10 MS4A8 MTTP MUC13 MUC17 MUC2 MUC3A MYO1A MYO7B MYRFL NAALADL1 NLRP6 P2RY4 PLCB3 PRAP1 PTPRH RBP2 REG4 SI SLC10A2 SLC13A1 SLC13A2 SLC15A1 SLC17A8 SLC23A1 SLC28A2 SLC3A1 SLC51B SLC5A1 SLC5A9 SLC6A19 SLC6A20 SLC7A9 SMIM24 SOAT2 SPINK4 TAS2R38 TM4SF20 TM6SF2 TMEM150B TMEM253 TMEM92 TMIGD1 TREH TUBAL3 UGT1A5 VIL1 VPREB3 XPNPEP2 Colon - Transverse Female 50-59 Up ANKS4B AOC1 ATOH1 B4GALNT2 BCL2L15 BEST2 BEST4 C15ORF48 CA1 CA7 CALML4 CAPN5 CASP6 CCL15 CDH17 CDX1 CDX2 CEACAM5 CEACAM7 CES3 CLDN3 CLDN7 CLRN3 DHRS11 DQX1 EFNA2 ENTPD8 EPCAM EPS8L3 ERN2 ETHE1 FABP1 FAM83E FCGBP FXYD3 GAL3ST2 GCNT3 GPA33 GPR35 GUCY2C HEPACAM2 HHLA2 HOXB5 HOXB9 HSD11B2 HTR3E IHH ISX KRT12 KRT20 KRT8 LEFTY1 LGALS4 LRRC19 LRRC31 LYPD8 MISP MOGAT3 MS4A12 MTMR11 MUC12 MUC2 NOX1 NXPE1 NXPE2 NXPE4 OMP OTOP2 PHGR1 PIGR PIGZ PLA2G10 PLS1 PPP1R14D PRR15 REP15 RXFP4 SATB2 SELENBP1 SLC26A2 SLC26A3 SLC44A4 SLC9A2 SMIM22 ST6GALNAC1 TJP3 TMEM236 TMEM54 TPSG1 TRABD2A TRIM31 TRPM6 TSPAN1 TSPAN8 UGT1A10 UGT1A8 UGT2B17 URAD VIL1 ZG16 Colon - Sigmoid Female 50-59 Up ABL1 ACTG2 ADAM33 ANKFY1 ARRDC4 ATP2B4 BAG2 BMP3 BTC CAB39L CACNA1C CACNA1H CCL11 CDK8 CHRDL2 CHRM2 CHRNA3 CNN1 COL24A1 COL6A1 CSRP1 EML1 FBXL22 FOXF1 FOXP2 FZD7 GALR2 GJC1 GLB1L2 GLI3 GLP2R HAND1 HAND2 HDAC4 HOXB3 HOXB4 HOXD10 HOXD11 HOXD12 HOXD13 ILK KCNMA1 KCNQ4 KIZ KLHL23 LIMS2 LRCH2 LRIG1 LRRC3 MAB21L2 MASP1 MDM1 MFHAS1 MID1 MRGPRD MRGPRF MYH11 MYLK NKX2-3 NKX3-2 NRP2 NT5DC3 NTSR1 NXN PBX3 PDE9A PDZRN3 PDZRN4 PGM5 PHOX2B PLA2G2C PLA2G4A PLEKHO1 PNCK PRPH PTBP2 PTCHD1 PTGFRN RAB23 RNF150 ROR2 SEMA3A SMTN SPOP STON1-GTF2A1L SYDE2 SYNM TACR2 TBC1D1 TEAD3 TES TGFB1I1 TMTC2 TNFAIP8L1 TSPAN11 TSPAN2 UBXN10 WNT9A ZACN ZNF219 Esophagus - Mucosa Female 50-59 Up A2ML1 ADH7 ALDH3A1 ANXA1 AQP3 BARX2 CALML3 CAPN1 CAPN14 CLCA2 CRABP2 CRNN CSTA CSTB CYSRT1 DSC2 DSG3 DYNAP EDAR EHF EMP1 EPGN EPHA1 EPHA2 EVPLL FABP5 FAM110C FAM135A FAM83A FGFBP1 FUT6 GBP6 GJB2 GPR78 GSTP1 IL1RN IL36A KLK13 KRT13 KRT15 KRT4 KRT6A LEXM LPAR5 LY6D LYPD2 MAB21L3 MALL MPZL2 MUC21 NMU OTOP3 PAX9 PITX1 PPL PROM2 PRSS27 RAB10 RAB25 RABGGTA RAET1E RAET1L RHCG RIPK4 S100A14 S100A16 S100A2 S100A8 SAMD9 SERPINB13 SIM2 SMAGP SOX15 SPINK5 SPRR1A SPRR2A SPRR3 TACSTD2 TBX6 TGM1 TGM3 THSD4 TMEM184A TMEM40 TMPRSS11A TMPRSS11B TMPRSS11D TMPRSS11E TMPRSS4 TRIM16 TTC22 TTC9 TTLL12 TXN TXNDC17 UGT1A7 USH1G VSIG10L ZDHHC13 ZNF185 Stomach Female 50-59 Up A4GNT ADAM28 AGR2 AKR1B10 AKR7A3 AKR7L ALDH1A1 ANKRD22 ANXA10 ARSD ATP4A ATP4B B4GALNT3 BAIAP2L1 BARX1 C9ORF152 CA2 CA9 CAPN13 CAPN8 CAPN9 CCKAR CCKBR CLDN18 CLIC6 COL2A1 CST11 CTSE CXCL17 CYP2S1 CYSTM1 EPN3 ERN2 ESRRB ESRRG FAM177B FER1L6 FMO5 FOXA2 FOXA3 FOXQ1 GALE GCNT4 GHRL GKN1 GKN2 GPER1 GPRC5C IL17REL ISL1 KCNE2 LGALS9C LIPF LIPH MCIDAS MECOM MFSD4A MLNR MUC1 MUC5AC MUC6 MYH13 NBPF12 OSBPL7 PALM3 PDILT PGA3 PGA4 PGA5 PGC PIK3C2G PSCA PTGDR2 RASSF6 REP15 RFLNA RFX6 S100P SLC26A9 SLC41A2 SLC4A2 SLC5A5 SLC9A2 SLC9A4 SSTR1 SULT1C2 TFF1 TFF2 TMED6 TMEM92 TOX3 TPCN2 TRIM50 TRIM73 TRIM74 VILL VSIG1 VSIG2 VWA2 XYLT2 Adrenal Gland Female 50-59 Up AADAC ABCB1 ABCF3 ADGRV1 AKAP7 AKR1B1 ALAD ALAS1 AMHR2 AOX1 AQP11 AS3MT ASB4 C2CD2 CELA1 CLRN1 CREBL2 CTNNAL1 CTSA CYB561A3 CYB5B CYP11A1 CYP11B1 CYP17A1 CYP21A2 DDB1 DEXI DHCR24 DLK1 EPHX1 FAM166B FAM43B FDX1 FDXR GALM GNPTG GNS GRAMD1B GSTA1 GSTA3 GSTA4 GSTA5 HDHD3 HSD3B2 HSPD1 HSPE1 IDH1 KCNJ5 KCNK3 KCNN2 KCNQ1 KLHDC8B KLHL4 LONP1 LRRC61 MAP3K15 MAP3K5 MC2R MCOLN3 MGARP MRAP MYO7A NR0B1 NR5A1 PAPSS2 PEBP1 PEX3 PLBD2 PLEK2 PORCN PPIF QPRT RARRES2 RDX RGN RMDN2 SCAP SCARB1 SEMA6A SERPINA5 SLC16A9 SLC23A2 SLC40A1 SLC47A1 SLC8B1 SNTB1 SOAT1 SREBF1 STAR TBC1D8B TBX3 TKFC TM7SF2 TMEM138 TMEM150C TRIM24 VWA5B2 WHRN ZNF275 ZNF280A Ovary Female 50-59 Up ACSM3 ADAMTS1 ADAMTS16 ADRB3 AMHR2 ANGPTL5 ARX ASIP BAMBI BNC2 BST2 C21ORF62 C7 CASP9 CDH11 CDH23 CDK15 CHST7 CLSTN2 CPZ CRYGD DET1 ECEL1 EML5 FKBP7 FOXL2 FOXL2NB FPGS GALNT10 GATA4 GATA6 GLI2 GREB1 GSTM2 GSTM5 HNRNPA1 HS3ST1 HS6ST2 IGFBP5 IGSF10 INHA IQCG KCNMB2 KLHDC8A LHX9 LPAR4 LRRC17 MCC MDK METAP1D MEX3A MMP21 NBL1 NECAB3 NFATC4 NR2F2 NRK NXPH2 NYNRIN OBSL1 PDGFRA PEG3 PHF6 PROK1 PTK7 RASL11B RBP1 ROBO3 RPL35A RPL5 RPS27 RPS3 RPS8 SIGLEC11 SIGLEC16 SIMC1 SLC7A2 SLC8B1 SNCAIP SOX4 ST13 SULF2 SULT1C4 SYTL4 TCEAL4 TCEAL9 TENM4 TMEM221 TMEM98 TRABD2A TSHZ3 TTC8 UBXN8 VLDLR VWCE WFIKKN2 WIPF3 WT1 ZNF556 ZNF66 Breast - Mammary Tissue Female 50-59 Up ABCB5 ABCC11 ADGRD2 AFP ALX4 ANKRD30A ANO1 ARHGEF38 ATP13A5 AUTS2 CCL28 CITED4 CLDN8 CMTM7 CRACR2B CX3CL1 CYP4Z1 DEFB132 ELF3 ELF5 ETV3L GABRP GJC3 GSC HCAR1 IL17RD IL22RA2 INHBB IRX1 IRX2 IRX3 IRX5 KIT LAMC2 LMX1B MAML2 MMP7 MRGPRX3 MUCL1 NAALADL2 NFIB NFKBIZ NTN4 OVCH2 OXTR PI15 PLEKHS1 RUNX1 SAV1 SCGB1D2 SCGB2A1 SCGB2A2 SCUBE2 SERHL2 SFRP1 SLC28A3 SLC39A6 SPINK8 STAC2 TANK TBC1D9 TFAP2B TFAP2C TIGD2 TNN TRPS1 TSHZ2 UGT2B11 VGLL1 VTCN1 ZNF552 Artery - Tibial Female 50-59 Up ACAN ACTA2 ACTN4 ADARB1 ADIRF AMIGO2 ARHGEF17 ARHGEF39 ATL3 ATP10A BCAM C11ORF96 C12ORF75 C1QTNF7 CDH6 CHSY3 CLIC4 CNTN4 COL14A1 COL18A1 CPED1 CRLF1 CRTC3 CSPG4 CSRP2 DACT3 DSTN EFHD1 FHL5 FOXC1 FOXC2 FRY GJA4 HES4 HEY2 HTR1B ID2 IGFBP7 ITGA5 JAG1 JAK2 KCNA5 KCNAB1 KCTD10 KLHL26 LMOD1 LPP MAP7D3 MCAM MEF2D MOB2 MSRB3 MUSTN1 MYBL1 NKD1 NOTCH3 NTF3 NTRK3 P2RX1 PDK3 PITPNB PLEKHG3 PMEPA1 PPP1R14A PRDM16 PRELP PRKG1 RASL12 RASSF3 RCAN2 RERGL RHOB RNF180 ROCK1 ROR1 SDK1 SH3BGRL SH3RF3 SMIM10 SMURF1 SORBS2 SPEG SPOPL SUN2 SUSD5 TAGLN TASP1 TBX18 TBXA2R TGM2 TLN1 TMEM181 TMEM47 TNS1 TOB2 TRABD2B UBA2 USP35 WTIP ZFHX3 Adipose - Subcutaneous Female 50-59 Up ACER2 ACKR2 ADAMTS5 ADCY4 ADGRL4 ADH1B ADRA2A AFAP1L1 AGTR1 AIFM2 AKR1C2 ANGPTL2 ANGPTL4 APOL3 APOLD1 AQP7 ARHGAP20 ARHGEF15 ATP8B4 AVPR2 BMP6 CD248 CD300LG CD34 CD36 CDH5 CFD CHRDL1 CIDEC CLDN5 CLEC14A CLEC3B CPM CYGB DOCK11 EBF1 EBF3 EDN1 EGFL6 FABP4 FAM124B FGD5 FZD4 GALNT15 GFRAL GGT5 GHR GPC3 GPD1 GPIHBP1 GPR146 GYG2 INHBB ITGB1BP1 ITIH5 KCTD12 KRTAP13-4 LEP LHX6 LIPE LRRC8C LVRN MAN1A1 MEOX1 MGLL MMRN2 NEDD9 NMT2 PECAM1 PLIN1 PLIN4 PNPLA2 PPARG PRKAR2B PTPRM RAMP2 RDH5 RNF125 S1PR1 SASH1 SEMA3G SESTD1 SIK2 SIM1 SLC19A3 SLIT3 SMIM3 SRPX2 STAT5A SYNE3 TGFBR3 TIMP3 TIMP4 TMEM132C TNMD UVRAG VKORC1L1 VWF WNT11 ZNF366 Artery - Aorta Male 30-39 Up ADAMTSL3 ADRA1B ADRA1D ADRA2C AEBP1 ANO1 AQP1 ART4 ASPN BGN C1QTNF2 CD151 CDH13 CNTN4 COL14A1 COL21A1 CPXM2 CRISPLD1 EFEMP1 ELN EOGT ERG EXT1 FBLIM1 FBLN5 FGL2 FIBIN FILIP1L FOXC1 FOXC2 GABRR1 GDF7 GEM GLIPR1 HAPLN3 HAUS7 HMCN1 IGFBP2 IGFBP7 IL13RA2 IL31RA ITGA10 ITGA11 ITGA8 ITGA9 ITGB5 KANK1 KCNK15 KCNK17 LDOC1 LGR6 LIMS4 LOXL1 LTBP1 LTBP2 LTBP3 MAN2B2 MEGF6 MFAP4 MFGE8 MGP MICAL2 MMP23B MRAP2 MYH10 MYH9 NOX4 NPR1 NXPH3 OGN OMD OSR1 PCDH7 PCDHB11 PID1 PKD2 PLD5 PLS3 PRDM16 PRDM6 PRKG1 PTGIR PTGIS PXDC1 SCUBE3 SLC41A2 SMOC2 SOD3 SPARCL1 ST6GAL2 SULF1 SUSD5 TBXA2R TC2N THBS2 TNFRSF11B TPH1 VCAN WWP2 ZNF385D Heart - Atrial Appendage Male 30-39 Up ACTC1 ADAMTS7 ADAMTSL2 ALPK2 ANKRD1 ASPG BCO2 BMP10 C14ORF180 C1ORF105 CASQ2 CIB2 CORIN COX7A1 COX7B CRIP2 CSDC2 CYCS DAND5 DHRS7C DKK3 DOK7 EIF1AY EIF1B FAM216B FAM78A FBXO40 FGF12 FGF23 FITM2 GATA4 GLP1R GRXCR2 HCN4 HHATL HRC HSPB2 HSPB3 HSPB7 IGSF5 ITGB1BP2 KCNIP2 LAPTM4B LPAR3 LRRC10 METTL7B MSRB2 MT1HL1 MTUS2 MYBPC3 MYBPHL MYH6 MYL4 MYL7 MYLK3 MYOZ2 MYZAP NDUFA1 NDUFA4 NDUFA8 NDUFAB1 NDUFB1 NEBL NKX2-5 NKX2-6 NMRK2 NPPA NRTN NUDT8 OR10P1 OR8B8 OTOGL PAM PLA2G5 POPDC2 PPP1R3G PTGDS PXDNL RABGAP1L RBPMS2 RD3L RILPL1 RYR2 S100A1 SBK2 SBK3 SCN5A SHD SLC41A1 SLC4A3 SMPX TBX20 TBX5 TECRL TMEM182 TNNI3K TNNT2 TSPAN18 UQCRB WNK2 Heart - Left Ventricle Male 30-39 Up ACTC1 ASB15 ASB18 BCO2 BSG BZW2 CASQ2 CCDC141 CDH2 CHCHD10 CKMT2 COQ10A COQ9 COX5A COX6A2 COX7A1 COX7B CPT1B CSRP3 CYC1 DAND5 DDO DECR1 ECSIT EIF1AY EIF1B FABP3 FGF12 FGF18 FHL2 FHOD3 FITM1 FITM2 GJA3 GOT1 HHATL HRC HSPB3 HSPB7 IDH2 KCNJ8 KLHL31 LDHB LRRC10 LSMEM2 MAPKAPK3 MDH1 MPC1 MT1HL1 MTUS2 MYBPC3 MYH7 MYH7B MYL2 MYL3 MYLK3 MYOM2 MYOZ2 MYZAP NDUFA1 NDUFAB1 NDUFB3 NDUFS6 NEBL NKX2-5 NUDT7 PDE1C PDHA1 PKP2 PLN POPDC2 PPM1K RBM20 RD3L RNF207 RYR2 S100A1 SCN5A SDHA SGCG SH3RF2 SLC16A7 SLC25A4 SLC41A1 SLC4A3 SMCO1 SMPX SMYD2 TCF15 TECRL TENM2 TLL2 TMEM143 TMEM182 TNNI3 TNNI3K TNNT2 TPM1 UQCRC1 XIRP1 Cells - Cultured Fibroblasts Male 20-29 Up ADAM12 ADAM9 ADAMTS2 ALDH1L2 ARSJ AZI2 BICC1 BRIX1 C6ORF120 CALU CCBE1 CCDC80 CD109 CEMIP CITED2 CLEC11A COL12A1 COL1A1 COL1A2 COL3A1 COL5A2 COL6A3 CYP19A1 DKK1 DSEL EDA2R EIF2AK4 FAP FBN1 FBN2 FKBP10 FKBP14 FN1 FRMD6 FSTL1 GCNT1 GDF5 GPR176 GPX8 GREM1 HIF1A HOXC8 HS3ST3B1 IGF2BP1 IGF2BP2 IGF2BP3 IKBIP KCNK2 KDELR3 LAMA4 LAMC1 LOX LOXL2 MAN2A1 MME NABP1 NECTIN3 NID2 OLFML3 OPN3 OR1Q1 PAPPA PCDH18 PCDHGA10 PCDHGA11 PCDHGA12 PCDHGB4 PCOLCE PLOD2 PRR16 PSG1 PTX3 PXDN RCN1 RCN3 RECK SBF2 SEC22B SIM1 SNAI2 SRGAP1 STEAP1 STEAP1B TGFBI TMEM119 TNFRSF10D TRAM1 TRAM2 TRIAP1 TTPAL TWIST1 TWIST2 TXNRD1 ULBP1 ULBP3 VGLL3 WNT5A XPOT YIPF5 ZNF281 Thyroid Male 20-29 Up AFAP1L2 AMELY ATP13A4 CCL21 CLN5 COL23A1 CPQ CROT CRYGN CTSB DIO1 DUOX2 EPOR EXOC3L2 FLT4 FOXE1 FREM2 FSCN2 GAL3ST3 GFRA2 GOLGA8M GOLGA8Q GOLGA8R GRK1 HHEX HIRA HOOK3 IFT140 INPP5J IQCA1 ISM1 IVD IYD KCNC3 KCNJ16 KLHL14 KNSTRN LCN12 LIPG LPCAT2 LRP2 LRP8 MBD6 MGAT4C MPPED2 MROH1 NKX2-1 NPNT OR11L1 OR2A1 OR2A42 OR2T8 PAX8 PBX4 PCSK2 PDE8B PKHD1L1 PLA2R1 PLEKHH1 PLVAP PPP1R13B PRTG RASSF4 RCBTB1 RGL3 RTN4RL2 S100A5 SALL1 SCX SDF2L1 SEMA3D SHISA2 SLC12A8 SLC16A11 SLC17A5 SLC26A4 SLC26A7 SLC4A11 SLC4A5 SLC5A8 SNX1 SNX22 SORD ST3GAL1 SUCNR1 TBL1Y TCERG1L TECTB TG TLE6 TPMT TPO TSHR TXNL1 WDR72 WFDC8 ZBED2 ZNF114 ZNF486 ZNF804B Adrenal Gland Male 20-29 Up AADAC ABCB1 ABCC3 ABCF3 ADGRV1 AKAP7 AKR1B1 ALAD ALAS1 AMHR2 AS3MT ASB4 BST2 C2CD2 C4B CELA1 CLRN1 CREBL2 CTNNAL1 CTSA CYB561A3 CYB5B CYP11A1 CYP11B1 CYP11B2 CYP17A1 CYP21A2 CYP2W1 DHCR24 DUSP16 EPHX1 ERV3-1 FAM166B FAM43B FBXO9 FDX1 FDXR FNDC4 GALM GIPC2 GNS GSTA3 GSTA4 HDHD3 HSD3B2 IDH1 IFITM10 KCNJ5 KCNK3 KCNN2 KCNQ1 KLHDC8B KLHL4 LONP1 LXN MAP3K15 MAP3K5 MC2R MGARP MRAP MRPL33 NR0B1 NR5A1 PAPSS2 PEG10 PLBD2 PLEKHA5 PORCN RARRES2 RBKS RDX RGN RMDN2 SCARB1 SEMA6A SERPINA5 SLC16A9 SLC37A2 SLC40A1 SLC47A1 SLC8B1 SMIM14 SNTB1 SOAT1 SREBF1 STAR SULT2A1 TBC1D4 TBX3 TKFC TM7SF2 TMEM150C TMEM200A TSFM TXN2 WHRN ZNF117 ZNF275 ZNF280A ZSWIM5 Lung Male 20-29 Up A2M ABCA3 ACOXL ACP5 ACVRL1 ADAMTS8 ADGRF5 ADGRL2 AGER ALPP ATP11A CACNA2D2 CASS4 CCL18 CCL23 CCRL2 CD68 CEACAM6 COL6A5 CSF2 CTSH DRAM1 DUOX1 EMP2 EPAS1 F2RL3 FGFR4 FLRT3 FOLR1 GALNT18 GGTLC1 GPRC5A HHIP HTRA4 ICAM1 IL1RL1 INMT ITGB6 KRT7 LAMP3 LPCAT1 LRRK2 LRRN4 MARCO MBIP MRC1 MS4A15 MSLN MTRR MUC1 NAPSA NCKAP5 NDNF NKD2 NPC2 OLR1 PARD6B PHEX PIGA RAB11FIP1 RBMS2 RGCC RHOBTB2 RIPPLY3 RNF145 ROS1 RS1 RTKN2 SDR16C5 SFTA2 SFTPA1 SFTPA2 SFTPB SFTPC SFTPD SHROOM4 SLAMF8 SLC26A9 SLC34A2 SLC39A8 SLC6A14 SLC6A4 SLCO2A1 SLCO4C1 SNX30 SUSD2 TBC1D2 TBX4 TCF21 TFEC TFPI TMEM100 TMEM125 TNFSF13 VEPH1 VIPR1 WNT2 WNT3A XAGE2 ZNF385B Spleen Male 20-29 Up ABI3 AIF1 ANXA2R APLNR ARHGAP4 BANK1 BTN3A3 C1QA C1QB C1QC CABP4 CARD16 CARD9 CCL14 CCL24 CCM2L CD163L1 CD180 CD19 CD1C CD1D CD4 CD52 CD5L CD72 CD79B CD8A CDCP2 CNR2 CR2 CSF1R CXCL13 CXCR5 CXCR6 EMID1 EXOC3L1 FASLG FCMR FCRL1 FCRL2 FCRL3 FES FGD2 FHOD1 GAB3 GDPD2 GDPD5 GIMAP1 GPR182 GRAP GSDMD HLA-DOB HLA-F HMOX1 HOMER3 HYAL1 HYAL2 IL10RA IL24 ITGAD KAZALD1 KLRK1 LILRA4 LRTM1 LTB MPEG1 MS4A7 NLRC3 NOS3 NOX5 NPY1R NR5A1 OR5AK2 P2RX5 P2RY6 P3H2 PARVG PCDH12 PDE6G PDLIM2 PLCB2 PPIAL4C PPM1N PSTPIP2 RENBP S100Z SCN11A SIGLEC12 SLC9A5 SP140L SPIC STAB1 STAB2 TLX1 TMC8 TRAPPC3L TTC24 UBASH3A UNC93B1 VCAM1 Pancreas Male 20-29 Up AMY1B AMY2A AMY2B ANXA4 AQP12A AQP12B ASCL5 BHLHA15 C4ORF19 CATSPERB CEL CELA2A CELA2B CELA3A CELA3B CFTR CLDN10 CLPS CLPSL2 CPA1 CPA2 CPB1 CTRB1 CTRB2 CTRC CTRL CUZD1 DCDC2 EPB41L4B ERICH5 ERO1B ERP27 FAM3B FBXW12 FKBP11 G6PC2 GATM GCG GLP1R GP2 GPR119 GSTA2 GUCA1C IAPP IL22RA1 INS KCNK16 KIRREL2 KLK1 LENG9 LHFPL5 MNX1 NEURL3 NR5A2 ONECUT1 OR10G4 P4HB PDCD4 PDIA2 PDX1 PGGHG PKHD1 PLA2G1B PNLIP PNLIPRP1 PNLIPRP2 PRDX4 PRSS1 PRSS2 PRSS3 PTF1A RBPJL REG1A REG1B REG3A REG3G RNF186 RRBP1 SCTR SEL1L SERPINA3 SERPINA4 SERPINI2 SLC16A12 SLC30A2 SLC30A8 SLC38A5 SLC39A5 SLC43A1 SLC4A4 SPINK1 SYCN TC2N TECPR1 TMED6 TPST2 TRPV6 UNC5CL XBP1 ZNF98 Skin - Not Sun Exposed (Suprapubic) Male 20-29 Up AADACL3 ABCA12 ACAD9 ACER1 ACSM6 AHNAK2 ALOXE3 ARHGEF19 ATP12A AWAT1 AWAT2 BCL11B BLMH BPIFC C1ORF74 CALML5 CAMSAP3 CARD18 CASP14 CERS3 COL17A1 CPA4 CST6 CTSV CYP4F22 DCD DCT DGAT2L6 DMKN DNASE1L2 DUSP7 ELOVL3 EPHB6 EPHX3 EPPK1 FAM83C FAM83G GAN GJB3 GJB4 GJB5 GSDMA HR HSD3B1 IFFO2 IGFL3 IL20RA IRX3 IRX4 KCNJ18 KCNK7 KLC3 KLK5 KLK7 KRT1 KRT14 KRT17 KRT77 KRT79 KRT80 KRTDAP LGALS7 LGALS7B LY6G6C LYPD5 LYPD6B MLANA NECTIN1 NIPAL4 NKPD1 OR5P2 PKP1 PLA2G2F PLA2G4F PM20D1 PMEL PNLIPRP3 PNPLA1 PSAPL1 RDH12 SBSN SDC1 SEC14L6 SERPINB5 SLC24A5 SLC46A2 SP6 SPINT3 SPRR4 TET3 TFAP2A THEM5 TINCR TNS4 TRPM1 TYR TYRP1 WFDC5 XCR1 ZNF273 Prostate Male 20-29 Up ABCC4 ALOX15B AMD1 ANO7 AR ARG2 ARHGEF38 BIK BMPR1B CDH26 CDYL2 CENPN CFAP69 CHRNA2 CLUL1 CPA6 CPAMD8 CPLX3 CPNE4 CREB3L4 DMXL1 EBF4 EFCAB12 EVX1 FAAH FBXL8 FEV FOLH1 FOXA1 GATA2 GCNT2 GLIS1 HOXA13 HOXB13 HOXD10 ISL1 KCNH6 KLK2 KLK3 KLK4 LMAN1L LPAR3 MLPH MSMB NEDD4L NEFH NKX3-1 NPY NR2E3 NTF4 OR51C1P OR51E1 OR51E2 PAK1IP1 PDE11A PLPP1 PNPLA7 POTEG POTEH POTEM PRAC1 PRAC2 PRIM2 RCAN3 RDH11 RFPL1 RFPL2 RIPPLY3 RLN1 SALL3 SCUBE2 SERPINB11 SHROOM1 SLC30A4 SLC44A4 SLC45A3 SORD SP8 SPDEF SRD5A2 STEAP2 TBC1D8 TESK2 TGM4 TMPRSS2 TRPM8 TRPV6 TTC6 UPK3A USP43 WNK4 XKR5 ZBTB42 ZNF350 ZNF613 ZNF761 ZNF813 ZNF816 ZNF827 ZNF888 Breast - Mammary Tissue Male 20-29 Up ABCC11 ACACB ACO1 ACOT4 ACVR1C ADAMTS3 ADH1B ADIPOQ ADRA2A AGPAT2 AIFM2 ANKRD30A APOL4 AQP7 ARHGAP40 ARHGEF15 ARHGEF38 BOK BTNL9 CD300LG CD36 CEBPA CIDEA CIDEC DUSP4 EGFLAM ELOVL5 ESR1 ESYT1 FABP4 FAH FAM89A FASN FGF10 FOXA1 FZD4 G0S2 GABRE GGCT GHR GPD1 GPR146 GSC HCAR1 HEBP2 ITIH6 KIF12 LGALS12 LHX6 LIPE MDFI MEOX1 MEST MOCS1 MYB NLRP13 NLRP8 NPY2R ORMDL3 PAPPA2 PEMT PEX11A PEX19 PI15 PLIN1 PLIN4 PLXNA4 PNPLA2 PPARG RAB6C RAI2 RBP7 RETSAT SCRN2 SEC14L2 SEMA3G SERHL2 SERPINF1 SGK3 SIK2 SLC19A3 SLC25A1 SOCS2 SPAAR SPDEF ST8SIA6 STAT5A STC2 SYNE3 TBC1D9 TFAP2B TMEM101 TMEM132C TMEM26 TRPS1 TTC6 VKORC1L1 XBP1 ZBED3 ZNF689 Testis Male 20-29 Up ANKRD31 ASZ1 BEND2 BPIFA2 BTBD18 C12ORF40 C18ORF63 C2ORF78 C5ORF47 CCDC172 CCDC73 CCNB3 CT55 CTAGE1 CTAGE9 CTCFL DAZL DCAF4L1 DCAF4L2 DCAF8L1 DDX4 DEFB119 DMRT1 DMRTB1 DMRTC2 DPPA5 ELSPBP1 ESX1 FBXO47 FMR1NB GAGE1 GOLGA8S HORMAD1 HSF5 IZUMO3 KDM4D KIAA1210 KIF4B MAEL MAGEA1 MAGEA10 MAGEA6 MAGEB1 MAGEB10 MAGEB3 MAGEB6 MAGEC1 MAGEC2 MAJIN MCMDC2 MEIOB MEIOC MORC1 NAA11 NLRP4 OTUD6A PIWIL1 PIWIL2 PRDM14 PRDM9 PRR23A PRR23C PSMA8 RAD21L1 RAD51AP2 RAD9B RBM44 RBM46 RBMXL2 RBMY1F RNF17 RSPH10B2 SLC25A31 SMC1B SPDYA SPDYE4 SPESP1 SPO11 STRA8 SYCP1 SYCP3 TAAR2 TAF1L TDRD1 TDRD15 TDRD5 TERB1 TERB2 TEX13C TEX13D TEX14 TKTL2 TOPAZ1 TPTE TRIM60 TRPC5OS TSPY1 TSPY2 TSPYL6 ZNF99 Esophagus - Mucosa Male 20-29 Up A2ML1 ADGRF1 ADH7 ANXA1 AQP3 CAPN1 CAPN14 CLCA2 CRABP2 CSTA CSTB CYSRT1 DEFB104B DSC2 DSG3 DYNAP ECM1 EHF EMP1 EPGN EPHA1 EPHA2 ERO1A FABP5 FAM135A FAM83A FGFBP1 FUT3 FUT6 GBP6 GJB2 GJB6 GPR78 GRHL3 IL1RN IL36A KLK10 KLK12 KLK13 KRT13 KRT4 KRT6A KRT6B LEXM LY6D LYPD2 MAB21L3 MALL MPZL2 MUC21 NMU OTOP3 PAX9 PGM2 PITX1 PPL PRSS22 PRSS27 RAB10 RABGGTA RAET1E RAET1G RAET1L RHCG RNF223 S100A14 S100A16 S100A2 S100A8 SAMD9 SCEL SERPINB13 SERPINB2 SERPINB3 SFN SMAGP SPINK5 SPRR1A SPRR1B SPRR2A SPRR2D SPRR3 TACSTD2 TGM1 TGM3 TMEM40 TMPRSS11A TMPRSS11B TMPRSS11D TMPRSS11E TMPRSS11F TMPRSS4 TRIM16 TTC22 TXN TXNDC17 UGT1A7 VSIG10L ZDHHC13 ZNF185 Esophagus - Muscularis Male 20-29 Up AARD ABCC1 ACTG2 ACTN1 ADCY5 ADH5 ADRB3 ALDH1B1 AMOTL1 ANKS1A ANTXR2 ARHGAP10 ARHGEF26 ARMC9 ARSB BTC CACNA1H CACNB2 CALD1 CCDC69 CHRM3 CNTNAP3 CNTNAP3B COL4A5 COL4A6 CST5 CYSLTR1 DAAM2 DGKG DHX35 DNAH11 DPYSL3 EPHA7 FAM124A FAM83D FBXO30 FNBP1 FOXF1 FOXF2 FOXP1 GPC4 HLF HOXA4 HPSE2 IL33 ITGA1 JPH2 KANK2 KCNB1 KCNMB1 KCNQ4 KLHL42 LHCGR LMOD1 LPP LSM11 MYH11 MYL9 MYLK NKD1 NKX6-1 NRP2 NT5DC3 NTN1 OCRL PALLD PARVA PGM5 PLEKHO1 PPP1R12A PRUNE2 PYGB RARB RBPMS RGMA RGMB RGS2 RPS6KA5 S1PR3 SCUBE1 SEMA3A SEMA3E SGMS2 SLC27A6 SLC2A12 SLC2A9 SLITRK3 SMTN SORBS1 STON1 SYDE2 SYNM SYNPO2 TEAD3 TPBG TRPC6 TTC23 WLS WWTR1 ZNF503 Stomach Male 20-29 Up A4GNT ADAM28 AGR2 AKR1B10 AKR7A3 AMACR ANXA10 ATP4A ATP4B B4GALNT3 BARX1 C9ORF152 CA2 CA9 CAPN13 CAPN8 CAPN9 CCKAR CCKBR CHIA CHRDL2 CLDN18 CLIC6 COL2A1 CST11 CTSE CXCL17 CYP2S1 CYSTM1 DAZ4 DGKD ESRRG FER1L6 FOXA2 FOXA3 FOXQ1 GALE GCNT4 GKN1 GKN2 GPRC5C GRP IL17REL KCNE2 LGSN LIPF LRRC3 MCIDAS MECOM MFSD4A MLNR MUC1 MUC5AC MUC6 MYH13 NBPF12 P2RY14 PALM3 PDILT PGA3 PGA4 PGA5 PGC PIK3C2G PSCA RASSF6 RFLNA SLC26A9 SLC5A5 SLC7A3 SLC9A2 SLC9A4 SULT1C2 TFF1 TFF2 TGFBR1 TMEM51 TMEM92 TOX3 TPCN2 TRIM50 UGT1A6 VSIG1 VSIG2 VWA2 XYLT2 Colon - Transverse Male 20-29 Up ANKS4B ATOH1 ATP10B B3GNT6 B4GALNT2 BCL2L15 BEST4 C15ORF48 CA1 CA7 CALML4 CAPN5 CASP6 CCL15 CDC42EP5 CDH17 CDX1 CDX2 CEACAM1 CEACAM5 CEACAM7 CHST5 CLCA1 CLDN3 CLRN3 DQX1 DSG2 EFNA2 ENTPD8 EPCAM EPHB2 EPS8L3 ERN2 ETHE1 FABP1 FAM83E FCGBP FXYD3 GAL3ST2 GCNT3 GPA33 GUCY2C HEPACAM2 HHLA2 HOXB9 HSD11B2 HTR3E IHH ISX KRT20 KRT8 LEFTY1 LGALS4 LRRC19 LRRC31 LYPD8 MISP MS4A12 MTMR11 MUC12 MUC13 MUC4 MYO7B NOX1 NPY4R NXPE1 NXPE2 NXPE4 OTOP2 PHGR1 PIGR PLA2G10 PLS1 PPP1R14D PRELID2 PRR15 PYY REP15 RETNLB RXFP4 SATB2 SELENBP1 SLC26A2 SLC26A3 SLC44A4 SLC9A2 ST6GALNAC1 TJP3 TMEM54 TNFRSF11A TRABD2A TRIM15 TRIM31 TRIM40 TSPAN1 TSPAN8 TUBAL3 UGT1A10 UGT1A8 URAD Small Intestine - Terminal Ileum Male 20-29 Up ACSL5 ADAM28 ADAMDEC1 ADGRG7 ALPI ANXA13 APOBEC1 BAIAP2L2 BANK1 BLK C17ORF78 CCL21 CCL25 CCR6 CCR9 CD19 CD1C CD1D CD40LG CD79B CDHR2 CEACAM18 CEACAM20 CLDN15 CNR2 CTLA4 CXCR5 DEFA5 DEFA6 DERL3 DMBT1 ERICH4 FABP2 FABP6 FAM151A FAM177B FCMR FCRL1 FCRL2 FCRL3 FCRL4 GBA3 GIMD1 GPR31 GPR82 HKDC1 HLA-DOB HNF4G IL17REL IL24 IL2RA ITLN2 KCNJ13 KLHL6 LGALS2 MADCAM1 MALRD1 MEP1B MS4A10 MTTP MUC3A MYO1A MYRFL NAALADL1 NLRC3 NLRP6 OR10G2 PARP15 PLA2G2D RBP2 REG4 SCML4 SI SIGLEC6 SIRPG SLC10A2 SLC15A1 SLC23A1 SLC25A53 SLC28A2 SLC5A9 SLC6A19 SLC7A9 SPIB TIFAB TM4SF20 TM6SF2 TMC8 TMEM253 TRAF3IP3 TREH TTC24 UGT1A5 VIL1 VPREB3 XPNPEP2 ZNF101 ZNF107 ZNF80 ZNF831 Nerve - Tibial Male 20-29 Up AATK AFAP1L2 ANGPTL7 APOD ARHGAP19 ARHGEF10 BIRC7 BMP8B CADM4 CASKIN2 CDH19 CDH7 CDO1 CHEK2 CLCN2 CLDN19 CLDN20 CNTF COL28A1 CYP4B1 DCLK3 DHH DRP2 EBF2 EGFL8 EGR2 EXTL1 FAM178B FGF4 FGFBP2 FMNL3 FOXD1 FOXD2 FOXD3 FRMD1 FRMD8 GAL3ST1 GAS2L3 GJC3 GLI1 HSPA12A IGFBP6 IL17B INF2 ITGA6 KANK4 KCNK12 KCTD11 KIF19 LCTL LGI2 LGI4 LHPP MAPK8IP1 MATN3 MIA MLIP MPZ NCMAP NDRG1 NEK1 NGFR NRIP2 OR6B2 OR6B3 OTUD7B PAPLN PLEKHA4 PLEKHG7 PLLP PMP2 PMP22 PRICKLE1 PRRG3 PRX PTPDC1 PTPRU RTKN SBSPON SECISBP2L SEMA3B SEMA4C SEMA5A SFRP5 SHC4 SLC16A12 SLC25A48 SLC2A1 SLC6A20 SMCO3 SORCS1 SPTBN5 ST6GALNAC2 TAX1BP3 TMEM215 TMPRSS5 USP53 VIT WNT6 ZDHHC8 Muscle - Skeletal Male 20-29 Up ABRA ACTA1 ADSL ALDOA ALPK3 AMFR ANKRD39 ASB12 ASB2 ASB5 BIN1 BTBD1 C19ORF47 CACNG1 CAND2 CHRNB1 CKM CMYA5 COQ8A CSDE1 CYB5R1 DCAF6 DDIT4L DUSP13 EEF1A2 EGLN1 EIF3J ENO3 EYA4 FBXO32 FEM1A FHL3 GAPDH GLRX GMPR IGFN1 IP6K3 JPH1 JSRP1 KCMF1 KCNA7 KCNJ11 KEAP1 KIF1C KLHL40 KLHL41 LBX1 LRRC2 MACROD1 MAFA MAPK12 MKNK2 MRLN MYL1 MYLK4 MYO18A NFE2L1 OBSCN OPTN OSBPL11 P2RX6 PERM1 PGM1 PHKA1 PHTF2 PLPP7 POPDC3 PRKAG3 PROB1 PYGM RAD23A RAPSN RPP25L RPUSD4 RYR1 SCN4A SIX4 SMTNL2 SOD2 SPTB STAC3 SYNPO TMEM11 TMEM233 TMEM38A TMOD4 TRDN TRIM54 TRIM63 TRIM72 TTN UBE2D4 UBR3 UCP3 USP38 UTP11 WWP1 YBX3 ZNF106 ZYG11B Skin - Sun Exposed (Lower Leg) Male 20-29 Up AADACL2 ABCA12 ACER1 ADGRF2 ADGRF4 ALOX12B ALOXE3 ANXA9 ASPRV1 ATP6V1C2 BLMH BPIFC C1ORF68 CALML5 CAMSAP3 CASP14 CASZ1 CDSN CERS3 CLDN1 CTNNBIP1 DAPL1 DCD DLX3 DLX5 DMKN DSC1 DSG1 DSP EFNA3 EPHX3 FAM83C FAM83G FLG FLG2 FOXN1 GAN GJB3 GSDMA HOXC12 HS3ST6 IFFO2 IL36B IL36RN KCNK7 KLC3 KLK5 KPRP KRT2 KRT80 KRTDAP LCE1A LCE1B LCE1C LCE1F LCE2B LCE2C LCE2D LCE4A LCE6A LIPM LY6G6C LYPD5 MYCL NIPAL4 NKPD1 NLRP10 OR10A3 OR10A6 PKP1 PLA2G2F PLA2G4E PNPLA1 POF1B POU2F3 PSAPL1 RDH12 RNF39 RORA SBSN SDR42E1 SDR9C7 SERPINA12 SERPINB12 SERPINB5 SERPINB7 SLC39A2 SLC46A2 SP6 SPTLC3 TGM5 THEM5 TINCR TMEM86A TMPRSS13 TREX2 TUFT1 UNC93A WFDC5 XKRX Brain - Amygdala Male 50-59 Up ACBD7 AIFM3 ALDH7A1 AMZ1 APC B3GAT1 BCAN C1QL2 CAMK2N1 CDH4 COX6A1 CPLX2 CPNE6 CSPG5 CTNNA2 CTNND2 DEAF1 DLL3 DOK6 DSCAM ELFN2 ENHO ETNPPL FAM107A FAM181B FBXO2 FEZF2 FXYD7 GAREM2 GDF11 GPM6A HDDC2 HIPK2 HMX1 HSD11B1L KCNIP1 KCNK4 KCNN1 KCTD4 KIF5A KIF5C LHFPL3 LHX2 LRRC3B LUZP2 MAP4K4 MAPK8IP2 MEIS3 MLC1 MT3 MTURN MYRIP NANOS3 NCAN NCS1 NECAB2 NKAIN3 NPAS3 NR2E1 NSMF NTRK2 NTSR2 OCM OLIG1 OLIG2 OPALIN OTOL1 PAIP2B PALM PCDH11Y PCDH15 PHACTR3 PLPPR1 PTPRZ1 RAPGEF4 RASL10A RIMS2 SCD5 SFXN5 SHANK1 SLC1A2 SLC25A18 SLC38A8 SLC6A1 SLCO1A2 SNCG SOX1 SOX2 STOX1 STUM SYTL5 TFAP2D TFPT TMEM160 TNR TRIL TSPOAP1 TTC9B UNC13C WNT7A Testis Male 40-49 Up ACRV1 ACTL7B BEND2 BTBD18 C12ORF40 C17ORF50 C18ORF63 C19ORF84 CABYR CCDC116 CCDC73 CCER1 CLPB CRYGC CT47B1 CTCFL DAZL DCAF12L1 DCAF4L1 DCAF4L2 DCAF8L1 DDX4 DDX53 DMRT1 DMRTB1 DNAJB8 DPPA2 ESX1 FAM47A FAM47B FAM47C FATE1 FBXO47 FNDC11 FOXR1 FOXR2 GAGE1 GAPDHS GSC2 LUZP4 LYZL4 MAGEA1 MAGEA10 MAGEA11 MAGEA12 MAGEA3 MAGEA4 MAGEA6 MAGEB1 MAGEB10 MAGEB16 MAGEB2 MAGEB3 MAGEB4 MAGEB6 MAGEC1 MAGEC2 MEX3B NAA11 NANOS2 NLRP4 OR2J3 PAGE2B PAGE5 PASD1 PRAME PRR23A PRR23B RAD51AP2 RBM46 RBMXL3 RFPL3 RHOXF2 SLC22A14 SMC1B SMIM21 SMKR1 SOX30 SPACA4 SPATA31C1 SPATA32 SPO11 SSX3 SYCP3 TAF7L TEX13D TFDP3 TGIF2LY TKTL1 TOPAZ1 TPPP2 TPTE TRIM60 TRPC5OS TSPYL6 USP26 ZFP42 ZNF280B ZNF479 ZSCAN5A Heart - Atrial Appendage Male 40-49 Up ACTC1 ADAMTS7 ADAMTSL2 ALPK2 ANKRD1 ASPG B3GLCT BCO2 BMP10 CASQ2 CCDC141 CHRNE CIB2 CORIN CRIP2 CYCS CYP2J2 CYSLTR2 DAND5 DHRS7C DKK3 DOK7 EIF1AY ENG FABP3 FBLN2 FBXO40 FGF12 FGF23 FITM2 GATA4 GRXCR2 HCN4 HHATL HRC HSPB2 HSPB3 HTRA3 IGSF5 ITGB1BP2 KCNIP2 KLHL31 LAPTM4B MDH1 METTL7B MT1HL1 MTUS2 MYBPC3 MYBPHL MYH6 MYL4 MYL7 MYLK3 MYOZ2 MYZAP NDUFAB1 NEBL NES NKX2-5 NMRK2 NPPA NPPB NRTN OR10P1 OTOGL PAM PCOLCE2 PLA2G5 POPDC2 PRKAG2 PRR32 PXDNL RABGAP1L RBM20 RBPMS2 RD3L RILPL1 RYR2 S100A1 SBK2 SBK3 SCN5A SHD SLC25A4 SLC41A1 SLC4A3 SLC8A1 SMPX SYNPO2L TBX20 TBX5 TECRL TMEM182 TNNI3K TNNT2 TRIM55 UQCRB USP28 WNK2 XIRP1 Heart - Left Ventricle Male 40-49 Up ACTC1 ADRB1 ASB18 BCO2 BSG CASQ2 CCDC141 CDH2 CHCHD10 CKMT2 COQ10A COX5A COX7A1 COX7B CPT1B CRYAB CSDC2 CSRP3 DAND5 DCUN1D2 DDO DECR1 ECSIT EIF1AY ETFDH FABP3 FGF18 FHL2 FHOD3 FITM2 GJA3 GOT1 HHATL HRC HSPB3 HSPB7 ITGB1BP2 KLHL31 LDB3 LDHB LRRC10 LSMEM2 MAPKAPK3 MDH1 MFN2 MLYCD MPC1 MT1HL1 MTUS2 MYBPC3 MYH7 MYH7B MYL2 MYL3 MYLK3 MYOM2 MYOZ2 MYZAP NDUFA1 NDUFA8 NDUFAB1 NDUFS6 NEBL NKX2-5 NMRK2 OGDH PDE1C PDHA1 PKP2 PLN POPDC2 PPM1K RBM20 RD3L RNF207 RYR2 S100A1 SCN5A SDHA SGCG SLC25A30 SLC25A4 SLC41A1 SLC4A3 SLC8A1 SMCO1 SMPX SMYD2 SRL SYNPO2L TCF15 TECRL TENM2 TNNI3 TNNI3K TNNT2 TPM1 UQCRC1 UQCRQ XPR1 Lung Male 40-49 Up A2M ABCA3 ACOXL ACP5 ACVRL1 ADAMTS8 ADGRF5 ADGRL2 AGER AGTR2 ALDH3B1 ALPP ATP11A BMP5 CACNA2D2 CALCRL CASS4 CCDC102B CCL18 CD101 COL6A5 COL6A6 COX4I2 CSF2 CTSH DRAM1 ECT2L EMP2 EPAS1 FCN3 FGFR4 FLRT3 FOLR1 GALNT18 GGTLC1 GPRC5A HECW2 HTR3C IL1RL1 IL7R INMT LAMP3 LPCAT1 LRRK2 LTK MARCO MBIP MRC1 MS4A15 MSR1 NAPSA NCKAP5 NDNF NKD2 NPC2 OLR1 PHEX PTPRB RBMS2 RGCC RHOBTB2 RNF145 ROS1 RP1 RS1 RSPO4 RTKN2 SCGB1A1 SCGB3A1 SCGB3A2 SFTA2 SFTPA1 SFTPA2 SFTPB SFTPC SFTPD SHROOM4 SLC34A2 SLC39A8 SLC6A4 SLCO2A1 SLCO4C1 SLIT2 SNTN STARD8 TAL1 TBX2 TBX4 TCF21 TFEC TFPI TMEM100 TMEM125 TMEM212 UNC13B VEGFD VIPR1 WNT2 WNT3A XAGE2 Esophagus - Muscularis Male 40-49 Up AARD ABCC1 ACTG2 ADCY5 ADRB3 ANKS1A ANTXR2 ARHGAP10 ARHGEF26 ARMC9 ARSB BCHE BTC CACNA1H CACNB2 CALD1 CCDC69 CHRM3 CNN1 CNTNAP3 CNTNAP3B COL4A5 COL4A6 CYSLTR1 DAAM2 DENND2A DGKG DHX35 DPYSL3 EPHA7 FAM83D FBXO30 FNBP1 FOXF2 FOXP1 GIPC3 GPC4 HDAC9 HLF HOXA4 HOXB2 HPSE2 ITGA1 JPH2 KANK2 KCNMB1 KCNQ4 KIAA0753 LHCGR LPP LSM11 MYH11 MYL9 MYLK NKX6-1 NRP2 NTN1 PALLD PGM5 PLEKHO1 PPP1R12A PPP1R12C PRUNE2 PYGB RARB RBPMS RGMA RGMB RGS2 RSPO3 S1PR3 SCUBE1 SEMA3A SLC2A12 SLITRK3 SMTN SORBS1 STON1 SYDE2 SYNM SYNPO2 TPBG TRPC6 TTC23 WLS WWTR1 ZNF503 Esophagus - Gastroesophageal Junction Male 40-49 Up ADCY5 ANKS1A ANTXR2 CACNB2 CHRM3 COL4A5 COL4A6 CYSLTR1 DGKG DHX35 DMPK EML1 FGL2 FOXF1 FOXF2 HIF3A HOXA3 HOXA4 HOXB3 HOXB4 HPSE2 KCNMB1 MAGEB17 MEIS1 MRGPRF MYH11 MYOC NKX6-1 NRP2 NTN1 P2RX2 PPP1R12C RBPMS RGMB RSPO3 SEMA3A SEMA3E SLC1A7 SMTN SYNM TOX2 ZNF503 Colon - Transverse Male 40-49 Up ADAMDEC1 ANKDD1B ANKS4B ATOH1 ATP10B B4GALNT2 BCL2L15 BEST2 BEST4 C15ORF48 CA1 CA2 CA7 CALML4 CAPN5 CASP6 CCL15 CDC42EP5 CDH17 CDX1 CDX2 CEACAM5 CEACAM7 CES3 CLCA1 CLDN7 CLRN3 DHRS11 DQX1 EFNA2 EPCAM EPHB2 EPS8L3 ERN2 ETHE1 FABP1 FAM83E FCGBP FOXH1 FXYD3 GAL3ST2 GPA33 GPR35 GUCY2C HEPACAM2 HHLA2 HOXB5 HOXB9 HSD11B2 HTR3E IHH ISX JCHAIN KRT20 KRT8 LEFTY1 LGALS4 LRRC19 LRRC31 MARVELD3 MS4A12 MTMR11 MUC4 NOX1 NXPE1 NXPE2 NXPE4 OMP OTOP2 PHGR1 PIGR PLA2G10 PPP1R14D PRR15 PYY REP15 RETNLB RXFP4 SATB2 SELENBP1 SLC26A2 SLC26A3 SLC44A4 SLC9A2 SMIM22 ST6GALNAC1 TMEM236 TMEM54 TPSG1 TRABD2A TRPM4 TSPAN1 TSPAN8 UGT1A10 UGT1A8 UGT2A3 UGT2B17 URAD VIL1 ZG16 Thyroid Male 40-49 Up AMELY ATP13A4 BMP8A C16ORF89 CLN5 COL23A1 CPQ CROT CRYGN CYTH2 DAPK2 DIO1 DUOX2 EPOR EXOC3L2 FOXE1 FREM2 FSCN2 GAL3ST3 GOLGA8M GOLGA8Q GOLGA8R GRK1 HHEX HIRA HOOK3 IFT140 INPP5J IQCA1 ISM1 IVD IYD KCNC3 KCNJ16 KLHL14 KNSTRN LCN12 LIPG LPCAT2 LRP2 LRP8 MARVELD2 MBD6 MBIP MGAT4C MPPED2 MROH1 MSANTD2 MUC15 NKX2-1 NPNT OR2A1 OR2T33 OR2T8 PAX8 PBX4 PCSK2 PDE8B PKHD1L1 PLA2G6 PLA2R1 PLEKHG4B PLEKHH1 PLVAP PPP1R13B PRKX PRTG RASSF4 RCBTB1 RGL3 S100A5 SALL4 SCX SEMA3D SH3D21 SHISA2 SLC12A8 SLC16A11 SLC17A5 SLC25A29 SLC26A4 SLC26A7 SLC4A11 SLC4A5 SLC5A8 SNX1 SNX22 ST3GAL1 TBL1Y TG TPMT TPO TSHR WDR72 ZBED2 ZNF114 ZNF486 ZNF737 ZNF804B ZNF90 Prostate Male 40-49 Up ALDH1A3 AMD1 ANO7 ARHGEF38 BMPR1B CDH26 CDYL2 CENPN CFAP69 CHRNA2 CPA6 CPAMD8 CPLX3 CPNE4 CREB3L4 CST4 CYP4F8 DMXL1 EBF4 EDDM3A ELK4 ENPP3 EVX1 FOLH1 FOXA1 GATA2 GCNT2 GLIS1 GRXCR1 HOXA13 HOXB13 ISL1 KCNH6 KLK2 KLK3 KLK4 LMAN1L MESP1 MLPH MON1B MSMB NEDD4L NEFH NKX3-1 NPY NR2E3 NTF4 OR2A4 OR2T35 OR51C1P OR51E2 PAGE4 PAK1IP1 PATE1 PATE2 PATE3 PATE4 PDE11A PLPP5 POTEG POTEH POTEM PRAC1 PRAC2 PRIM2 RDH11 RFPL2 RLN1 RPS4Y2 SCUBE2 SEMG1 SEMG2 SERPINB11 SHROOM1 SLC16A8 SLC30A4 SLC45A3 SOCS2 SORD SP8 SPDEF SRD5A2 STEAP2 STYK1 TBC1D8 TBX3 TGM4 TMEM141 TMPRSS2 TRPM8 TRPV6 TTC6 UPK3A USP43 XKR5 ZNF350 ZNF613 ZNF761 ZNF827 ZNF888 Cells - EBV-transformed Lymphocytes Male 60-69 Up ADGRG5 ANGPTL6 APOBEC3H ATAD5 B3GNT2 BATF BFSP2 BLM BLNK BORA BTK BTLA C17ORF99 CCL22 CCR7 CCR8 CD226 CD48 CD70 CD79A CD80 CENPM CLEC17A CPOX DNA2 E2F7 EAF2 EBI3 EDEM1 ESCO2 FAM111B FAM72B FAM72D FCER2 FCRLA GCSAM GNGT2 GPR15 GPR55 HELLS HMX2 HMX3 HVCN1 IFIH1 IKZF2 IKZF3 IL21R IL4I1 IRF4 IRF5 ITGB7 LGALS14 LPXN LTA LY75 MAP4K1 MCM2 MCOLN2 MX1 MYBL2 MYL12BP2 NEK6 NFKBIE NUP210 OAS2 OR2T3 OR6S1 ORC1 P2RY10 PAX5 PIF1 PIK3R6 PLCG2 PMAIP1 PNOC POLQ POU2AF1 RAD54B RFC3 SCIMP SLAMF1 SLAMF7 SNX25 SPN TEC TIFA TLR10 TLR7 TNF TNFRSF13B TNFRSF17 TNFRSF8 TNFSF9 TRAF1 TSPAN33 TTF2 VASH2 WDFY4 ZFAT ZNF318 Brain - Amygdala Male 60-69 Up ACBD7 AIFM3 ALDH7A1 AMZ1 APC B3GAT1 BCAN C1QL1 C1QL2 CAMK2N1 CDH20 CDH4 COX6A1 CPNE6 CSPG5 CTNNA2 CTNND2 DEAF1 DLL3 DSCAM DTNA ELFN2 ENHO ETNPPL FAM107A FAM181B FBXO2 FGF1 FXYD7 GDF11 GPM6A HDDC2 HIPK2 HMX1 HSD11B1L KCNG4 KCNIP1 KCNK4 KCNN1 KCTD4 KIF5A KIF5C KLRC2 KLRC3 LHFPL3 LHX2 LIX1 LUZP2 LY6H MAP4K4 MAPK8IP2 MEIS3 MLC1 MT3 MTURN MYRIP NANOS3 NCS1 NECAB2 NKAIN4 NPAS3 NR2E1 NTNG2 NTRK2 NTSR2 OCM OLIG1 OLIG2 OPALIN PAIP2B PALM PCDH11Y PCDH15 PHACTR3 PTPRZ1 RAPGEF4 RASL10A RIMS2 RTP5 SCD5 SFXN5 SHTN1 SLC25A18 SLC38A8 SLCO1A2 SMOX SNCG SOX2 STON2 STOX1 STUM SYTL5 TFAP2D TFPT TMEM160 TNR TTC9B TTYH1 UCMA ZBTB8B Brain - Spinal Cord (Cervical C-1) Male 60-69 Up ABCA2 ADARB2 AGPAT4 ANLN APLP1 BACE1 BCAS1 CA14 CARNS1 CDK18 CHADL CHRM5 CLDND1 CMTM5 CNDP1 CNP CNTN2 CNTNAP4 CTNNA3 DBNDD2 DPYSL5 DTNB ENPP6 ERMN EVI2A FA2H FEZ1 FGFR2 FMNL2 FNTB GAL3ST1 GFAP GJC2 GPM6B GPR37 GPR62 HAPLN2 HMSD HOXD1 HSPA2 KLK6 LANCL1 LHPP LLGL1 LRRC63 MAG MAP7 MARCKSL1 MBP MOB3B MOBP MOG MTMR10 MTURN MVB12B MYRF NIPA1 NKAIN2 NKX2-2 NKX6-2 OR5J2 OR9A2 PACS2 PAQR4 PAQR6 PAQR8 PCSK6 PEA15 PEX5L PIP4K2A PKP4 PLEKHB1 PLP1 PRRG1 PSRC1 RAPGEF5 RASSF2 RBM11 RNF13 S100B SEMA4D SIRT2 SLAIN1 SLC44A1 SLC5A11 ST18 STMN4 SYNJ2 TBC1D12 TF TMEM144 TMEM151A TMEM88B TNFRSF21 TP53INP2 TRAK2 TTYH2 TUBA1A UGT8 ZNF488 Whole Blood Female 30-39 Up ABTB1 AGTRAP ALOX5AP APOBEC3A APOBR AQP10 AQP9 ARHGAP9 ARHGDIB ARL11 BIN2 BST1 C16ORF54 C19ORF38 C1ORF162 CD53 CDA CFP CSF3R CXCR1 CYBA EFHD2 EVI2B FCER1G FCGR1A FCGR2A FCGR3B FGD3 FLOT2 FPR1 FRAT1 FRAT2 FUT7 GLIPR2 GLT1D1 GMIP GP9 GPR141 GPSM3 HCK ICAM3 IGSF6 IL18RAP IMPDH1 ITGB2 JAML LILRA2 LILRA5 LILRA6 LILRB3 LPAR2 LY6G6F MEFV MMP25 MNDA MSRB1 MYD88 MYO1F NCF1 NCF2 NCF4 NFAM1 NFE2 NLRC4 NLRP12 NPL OSCAR P2RY13 PF4 PGLYRP1 PLBD1 PPBP PTAFR PYCARD PYGL R3HDM4 RASGRP4 REM2 RGL4 RGS19 RHOG S1PR4 SECTM1 SELL SELPLG SHKBP1 SIGLEC5 SIRPB2 SLC22A4 SPI1 TALDO1 TLR1 TLR5 TNFAIP8L2 TREML1 TYROBP VAV1 VNN2 VSIR ZDHHC18 Cells - Cultured Fibroblasts Female 30-39 Up ADAM9 ADAMTS6 ALDH1L2 ANXA2 ARSJ ASPM CALR CALU CCBE1 CCDC80 CCNB1 CD109 CDK15 CENPE CENPF CHML CKAP4 CLEC11A COL1A1 COL1A2 COL5A2 COL6A3 CUL4B DCBLD1 DCBLD2 DEPDC1 DKK1 ECT2 EMC1 FAP FBN1 FBN2 FKBP10 FN1 GANAB GCNT1 GPX8 HERC4 HIF1A HMGA2 HS3ST3A1 HS3ST3B1 IGF2BP2 IGF2BP3 IKBIP IQGAP3 KDELR3 KIF20A KIF23 KIF4A LGALS1 LMAN1 LOX LOXL2 MME MSTN NECTIN3 NID2 NT5E OPN3 P4HA2 PAPPA PCDHGA11 PCDHGA12 PCDHGB4 PCOLCE PDIA6 PLOD1 PLOD2 PRR11 PRSS12 PSG1 PSG2 PSG4 PSG5 PSG9 PTGER2 PTX3 RCN1 RCN3 SEC22B SPC24 SPOCD1 STEAP1 STEAP1B STT3A TGFBI TK1 TOP2A TRAM2 TRNP1 TRPA1 TWIST1 TWIST2 TXNRD1 UGGT1 ULBP3 VGLL3 WNT5A YIPF5 Thyroid Female 30-39 Up ATP13A4 BMP8A CLN5 COL23A1 CRYGN CYTH2 DGKI DIO1 DIO2 DUOX2 EPOR EXOC3L2 FAM167A FOXE1 FSCN2 GAL3ST3 GFRA2 GOLGA8M GOLGA8Q GOLGA8R GRK1 HHEX HIRA HOOK3 IFT140 IL15 INPP5J ISM1 IVD IYD KATNAL2 KCNJ16 KLHL14 LCN12 LIPG LPCAT2 LRP8 LRRC75B MBD6 MGAT4C MROH1 MSANTD2 MTCH1 NKX2-1 NPNT OR11L1 OR2A1 OR2A42 OR2T33 OR2T8 PAX8 PBX4 PDE8B PKHD1L1 PLA2G6 PLEKHG4B PLEKHH1 PLVAP PPIL2 PPP1R13B PRKX PRTG RASSF4 RCBTB1 RGL3 RIOX2 S100A5 SALL1 SALL4 SCUBE3 SCX SEMA3D SHISA2 SLC12A8 SLC16A11 SLC17A5 SLC25A29 SLC25A45 SLC26A4 SLC26A7 SLC4A11 SLC5A5 SLC5A8 SNX22 SORD SUCNR1 TFF3 TG TLE6 TMEM50B TPMT TPO TSHR WDR72 ZBED2 ZNF114 ZNF486 ZNF737 ZNF804B ZNF90 Lung Female 30-39 Up ABCA3 ACOXL ACP5 ACVRL1 ADGRF5 ADGRL2 AGER AGTR2 ALDH3B1 ANKUB1 ANOS1 ATP11A BPIFB1 C10ORF95 C22ORF15 CACNA2D2 CASS4 CCDC17 CDHR4 CEACAM6 CSF2 CTSH CYP2F1 DCDC2B DNAH5 DRAM1 ECT2L EMP2 EPAS1 FCN3 FLRT3 FOLR1 GBP4 GGTLC1 GIMAP8 GPRC5A GRIN3B HHIP ICAM1 IDO1 IL18BP ITGB6 LAMP3 LDLRAD1 LPCAT1 LRRK2 MBIP MPL MRC1 MS4A15 MSR1 MTRR MUC1 NAPSA NDNF NPC2 PARD6B PHEX PTPRB RAB11FIP1 RBMS2 RHOBTB2 RNF145 ROS1 RP1 RS1 RSPH4A SCGB1A1 SCGB3A1 SCGB3A2 SEC14L3 SFTA2 SFTPA1 SFTPA2 SFTPB SFTPC SFTPD SGMS2 SLC34A2 SLC39A8 SLC6A14 SLC6A4 SLCO2A1 SLCO4C1 SMAD6 SNTN SNX30 SUSD2 TBX4 TFEC TFPI TMEM100 TMEM125 TMEM212 TSPAN19 UNC13B VEPH1 VIPR1 WDR38 XAGE2 Artery - Aorta Female 30-39 Up ADAMTSL3 ADRA1B ADRA1D ADRA2C AEBP1 ANO1 ART4 ASPN BGN C1QTNF2 CDH13 CLEC18A CNTN4 COL14A1 COL21A1 CPXM2 CRISPLD1 EFEMP1 ELN EOGT ERG EXT1 FBLIM1 FBLN5 FGL2 FIBIN FILIP1L FOXC1 FRZB GABRR1 GDF7 GLIPR1 GRK5 HAUS7 HMCN1 IGFBP7 IL31RA ITGA10 ITGA11 ITGA8 ITGA9 KALRN KANK1 KCNK17 KLHL42 LDOC1 LGR6 LIMS3 LIMS4 LOXL1 LTBP1 LTBP2 LTBP3 MAN2B2 MEGF6 MFGE8 MGP MRAP2 MYH10 MYH9 MYOCD NAV2 NOX4 NPR1 NXPH3 OGN OMD OSR1 PCDH7 PCDHB11 PDE5A PDGFD PID1 PKD2 PLD5 PLS3 PMEPA1 PRDM16 PRDM6 PRKG1 PROS1 PTGIS PXDC1 SCUBE3 SMOC2 SNX18 SOD3 SPARCL1 ST6GAL2 STAC STK38L SUSD5 TBXA2R TC2N THRB TMEM47 TNFRSF11B TPH1 WWP2 ZNF385D Heart - Atrial Appendage Female 30-39 Up ACTC1 ADAMTS7 ALPK2 ANKRD1 ASPG ATP2A2 B3GALT2 B3GLCT BMP10 CASQ2 CCDC141 CHRNE CIB2 CORIN CRIP2 CSDC2 CYCS CYP2J2 DAND5 DHRS7C DKK3 EDA FBXO40 FGF12 FITM2 GATA4 GJA5 GPD1L HCN4 HHATL HRC HSPB3 IDH3A IGSF5 ITGB1BP2 KCNA5 KCNIP2 KLHL31 LAPTM4B LPAR3 LRRC10 METTL7B MGAT5 MT1HL1 MTUS2 MYBPC3 MYBPHL MYH6 MYL4 MYL7 MYLK3 MYOZ2 MYZAP NDUFA4 NDUFAB1 NEBL NES NKX2-5 NKX2-6 NMRK2 NPPA NRTN NTN1 OR10P1 OTOGL PAM PKP2 PLA2G5 POPDC2 PRKAG2 PRR32 PXDNL RABGAP1L RBM20 RBPMS2 RD3L RHBDL3 RILPL1 RYR2 SBK2 SBK3 SCN5A SHD SLC25A4 SLC41A1 SLC4A3 SLC8A1 TBX20 TBX5 TECRL TMEM178B TMEM182 TNNI3K TNNT2 TRIM55 TSPAN18 UQCRB VWDE WASHC2A WNK2 Adipose - Visceral (Omentum) Female 30-39 Up ACOD1 ADAMTS1 ADAMTS15 ADAMTS4 ADIPOQ AGPAT2 AIFM2 ALDH1A3 AQP7 ARHGEF15 BDKRB2 CCDC71L CCL2 CCNL1 CD93 CDC42EP2 CDC42EP4 CDKN2C CH25H CIDEA CIDEC CPSF4L CRISPLD2 CXCL2 DCUN1D3 DDX3X DLC1 DUSP6 ELOVL5 FABP4 FAM110D FAM89A FASN FOSB G0S2 GFPT2 GGCT GPAM GPBAR1 GYG2 HAS1 HEBP2 IL10 IL1B IL6 KDM6B LGALS12 LIF LPL MAP3K8 MCL1 MDFI MEDAG MEST MGST1 MMP19 MT1A MT1E MT1M MT2A MYC NMB NOCT NWD2 NXNL1 OR2B11 OR52N1 OR52N5 PDPN PIM1 PLAU PLIN1 PLXNA4 PNPLA2 PPARG PPP1R15B PRKAR2B PRRT4 RARRES1 RASD1 RDH5 RGS16 SCD SELE SERTAD1 SLC25A1 SLC25A25 SLC29A4 SLC7A10 SMIM3 SNAI1 SOCS3 SOX17 SRPX THRSP TIMP4 TMEM132C TMEM88 TRIB1 ZFP36 Esophagus - Mucosa Female 30-39 Up A2ML1 ADGRF1 ADH7 ALDH3A1 ANXA1 C6ORF132 CAPN1 CAPN14 CBR3 CLCA2 CNFN CRNN CSTA CSTB CYSRT1 DSC2 DSG3 ECM1 EHF EMP1 EPGN EPHA1 EPHA2 ERO1A ESPL1 FAM83A FGFBP1 FUT6 GBP6 GDPD3 GJB2 GJB6 GPR78 GRHL3 GSTP1 IL36A KLK10 KLK12 KLK13 KRT13 KRT15 KRT4 KRT6A LEXM LYPD2 MAL MALL MPZL2 MUC21 MUC22 N4BP3 NLRX1 NMU OTOP3 PAX9 PPL PRSS22 PRSS27 RAB10 RAB25 RABGGTA RAET1E RAET1L RHCG S100A14 S100A16 S100A8 SAMD9 SCEL SERPINB1 SERPINB13 SERPINB2 SERPINB3 SMAGP SNX31 SOWAHB SPINK5 SPRR1A SPRR2A SPRR3 TACSTD2 TGM1 TGM3 TMEM40 TMPRSS11A TMPRSS11B TMPRSS11D TMPRSS11E TMPRSS11F TMPRSS4 TP53I3 TRIM16 TTC22 TTC9 TXN TXNDC17 UGT1A7 VSIG10L ZDHHC13 ZNF185 Esophagus - Muscularis Female 30-39 Up AARD ABCC1 ACTG2 ACTN1 ADRB3 ALDH1B1 ANKS1A ANTXR2 ARHGAP10 ARHGEF26 ARMC9 ARSB BTC CACNA1H CACNB2 CALD1 CBLL1 CHRM3 CNTNAP3 CNTNAP3B COL4A5 COL4A6 CSRP1 CST5 CYSLTR1 DAAM2 DGKG DNAH11 DPYSL3 EML1 EPHA7 FAM83D FBXO30 FLNA FNBP1 FOXF2 GPC4 GRPR HDAC9 HLF HOXA4 HPSE2 HTR2B IGSF9B INPP5A ITGA1 JPH2 KANK2 KCNMB1 KIAA0753 KITLG KLHL23 LHCGR LPP LSM11 MXI1 MYH11 MYL9 MYLK NKD1 NKX6-1 NRP2 NTN1 OCRL PALLD PARVA PCDHAC1 PGM5 PLEKHO1 PPP1R12A PPP1R12B PRUNE2 PYGB RAB4A RAP1A RARB REEP1 RGMB S1PR3 SCUBE1 SEMA3A SEMA3E SGMS2 SLC27A6 SLC2A12 SLITRK3 SLMAP SMTN SORBS1 STON1 SYDE2 SYNC SYNM SYNPO2 TPBG TPM1 TRPC6 TTC23 WLS WWTR1 Esophagus - Gastroesophageal Junction Female 30-39 Up ADARB1 ADCY5 ADH5 ANKS1A ANTXR2 ARHGAP10 ARMC9 ARRB1 ARSB ATL2 BCHE BTC CACNA1H CACNB2 CALD1 CHRM3 CNTNAP3 CNTNAP3B COL4A5 COL4A6 CYSLTR1 DAAM2 DGKG DHX35 DNAH11 EML1 EPHA7 FBXO30 FGL2 FNBP1 FOXF1 FOXF2 GPC4 GRPR HDAC9 HLF HOXA2 HOXA4 HPSE2 INPP5A ITGA1 JPH2 KANK2 KCNMA1 KCNMB1 KIAA0753 KLHL42 LMOD1 MAGEB17 MAMDC2 MAP3K20 MRGPRF MYH11 MYLK MYOC NKD1 NKX6-1 NRP2 NTN1 PALLD PARVA PCDH7 PCDHAC1 PDE5A PDZRN3 PGM5 PLEKHO1 PPP1CB PPP1R12A PRUNE2 RAB4A RAP1A RGMB ROR2 RSPO2 RSPO3 S1PR3 SCMH1 SCUBE1 SELENOM SEMA3A SEMA3E SLC2A12 SLITRK3 SMTN SORBS1 STON1 SYNM SYNPO2 TACR2 TAF9B TES TGFB1I1 TOX2 TRPC6 TTC23 WLS WWTR1 ZHX3 ZNF503 Colon - Transverse Female 30-39 Up ANKDD1B ATOH1 ATP10B B3GNT6 BAIAP2L2 BCL2L15 BEST4 C15ORF48 CA1 CA7 CALML4 CAPN5 CASP6 CCL15 CDH17 CDX1 CDX2 CEACAM1 CEACAM5 CEACAM7 CES3 CLRN3 DQX1 DSG2 EFNA2 ENTPD8 EPCAM EPS8L3 ERN2 ETHE1 FAM83E FCGBP FXYD3 FZD5 GAL3ST2 GALNT12 GCNT3 GNE GPA33 GPR35 GUCY2C HEPACAM2 HHLA2 HOXB9 HSD11B2 IHH KRT20 KRT8 LEFTY1 LGALS4 LRRC19 LYPD8 MIER3 MISP MS4A12 MTMR11 MUC12 MUC13 MUC2 MYO7B NOX1 NPY4R NXPE1 NXPE2 NXPE4 OTOP2 PDE9A PHGR1 PIGR PIGZ PLA2G10 PLS1 PPP1R14D PRELID2 PRR15 REP15 RETNLB RXFP4 SATB2 SELENBP1 SLC26A2 SLC26A3 SLC35A3 SLC44A4 SLC9A2 ST6GALNAC1 TMEM236 TMEM54 TPSG1 TRIM15 TRIM31 TRPM6 TSPAN1 TSPAN8 UGT1A10 UGT1A8 URAD VIL1 XK ZG16 Spleen Female 30-39 Up ABI3 BTN3A1 C1QA C1QB C1QC CABP4 CARD9 CASP10 CCL14 CCL24 CCM2L CD163L1 CD180 CD1D CD38 CD4 CD5L CD72 CD79B CD8A CDCP2 CETP CNR2 CPLX3 CSF1R CXCL13 CXCL6 CXCR5 DERL3 DLL1 DNASE1L3 EMID1 EPHA8 EXOC3L1 FAM43A FAM9C FCRL1 FCRL3 FCRL5 FGD2 FHOD1 FLI1 GDPD2 GDPD5 GIMAP1 GPR142 GPR182 HLA-DOB HMOX1 HYAL1 HYAL2 IL10RA ITGAD KAZALD1 LAX1 LILRB1 LILRB5 LIPA LRTM1 MIXL1 MPEG1 MS4A7 MZB1 NLRC3 NOS3 NOX5 NPY1R NR5A1 NTN4 OR5AK2 OR9G4 P2RX5 P2RY6 P3H2 PARP15 PDLIM2 PIM2 PITPNM3 PRR5L PSTPIP2 RENBP S100Z SEMA3D SIGLEC12 SLC9A5 SPIC STAB1 STAB2 TAS1R3 TDGF1 TLX1 TM4SF18 TMC8 TMEM156 TMEM26 TRAPPC3L TXNDC5 UNC93B1 VCAM1 ZBP1 Colon - Sigmoid Female 30-39 Up ACTG2 ANKFY1 ATP2B4 BAG2 BMP3 BMPR1A BTC CAB39L CACNA1C CACNA1H CCL11 CDK8 CHRM2 CNN1 CSRP1 DIP2C EMILIN1 EML1 FBXL22 FOXF1 FOXP2 FXYD6 GJC1 GLP2R HAND1 HAND2 HDAC4 HEPH HMCN2 HOXB3 HOXD10 HOXD11 HOXD12 HOXD13 ILK KANK2 KCNH2 KCNMA1 KCNQ4 KIZ KLHL23 KLHL5 LBR LIMS2 LRCH2 LRIG1 MAB21L2 MDM1 MID1 MRGPRD MRGPRF MYLK MYOCD NKX2-3 NKX3-2 NPY4R NRP2 NT5DC3 NTSR1 NXN PBX1 PDE3B PGM5 PHOX2B PLA2G2C PLA2G4A PLEKHO1 PPP1R12B PTBP2 PTCHD1 PTGFRN PTGS1 RAB23 RAP1A RASSF3 RNF150 ROR2 RSPO2 SEMA3A SEMA3C SLMAP SPOP SSC5D STON1 SYDE2 SYNM TACR2 TBC1D1 TEAD3 TES TGFB1I1 TMEM252 TMTC2 TNFAIP8L1 TSPAN11 TSPAN2 TTC23 UBXN10 XK ZEB1 Ovary Female 30-39 Up ACSM3 ADAMTS16 ADRB3 ANGPTL5 ARMCX4 ARX ASIP BAMBI BNC2 BST2 C21ORF62 C7 CASP9 CCDC8 CCL26 CDH11 CDH23 CHST7 CLSTN2 COL16A1 COLEC11 CPZ CTH DAPK1 DET1 ECEL1 EML5 ESR2 FBXO21 FKBP7 FOXL2 FOXL2NB GALNT10 GATA4 GATA6 GLI2 GREB1 GSTM5 HS3ST1 HSD17B1 IGFBP5 IGSF10 INHA KLHDC8A LHX9 LPAR4 LRRC17 MCC MDK MEX3A MMP21 MOB3B NECAB3 NLGN4X NLRP5 NR2F2 NRK NYNRIN OBSL1 PADI6 PDGFRA PEG3 PLCXD3 PROK1 PRPS2 PTK7 RASL11B RBP1 ROBO3 SIGLEC11 SIGLEC16 SIMC1 SLC7A2 SLC8B1 SMC5 SNCAIP SOX4 ST13 SULF2 SYTL4 TCEAL1 TCEAL4 TCF23 TDGF1 TDGF1P3 TENM4 TMEM221 TMEM98 TRABD2A TRIB2 TSHZ1 TSHZ3 UBXN8 VLDLR VWCE WFIKKN2 WIPF3 WT1 ZNF66 ZP4 Uterus Female 30-39 Up ADAM33 ADAMTS19 AKAP13 ALDH1A2 ATP2B4 AXIN2 BAG2 BNC2 CDKL1 CPXM1 CUX1 DCHS1 DPP6 EMX2 ENPP1 ESR1 FBXL22 FREM1 FRMD7 GAS1 GATA2 GJC1 GLI3 GNA14 GPR161 GUCY1A2 HOXA10 HOXA11 HOXA6 HOXD10 HOXD11 HOXD3 HOXD4 HOXD9 HTR2B HUNK IL17RD ISLR ITGA11 KCNG1 KDR KLHL13 LEFTY2 LINGO2 MASP1 MEIS1 MEIS3 MFAP2 MITF MMP11 MMP26 MOXD1 MRGPRF OSR2 PAMR1 PBX1 PCDHB7 PGR PLEKHH2 PMEL PRLR PTGER3 PTK7 RAB23 RAD51B RAMP1 RAP2C RERG REV3L RPRM RSPO1 SERTM1 SFRP4 SFT2D2 SLC24A3 SLC37A3 SLC7A3 SNCAIP SSC5D STK26 STRA6 SULF2 SYTL4 TAB3 TBC1D1 TBL1X TCEAL4 TCF23 TEX15 TMEM123 TMEM158 TMEM200A TMEM200B TNFAIP8L3 TRPC4 TSHZ3 WT1 XKR5 ZDHHC14 ZNF516 Breast - Mammary Tissue Female 30-39 Up ADGRD2 ADIPOQ AGPAT2 AIFM2 ALX4 APOL4 AQP7 ATP13A5 BTN1A1 CAPN6 CCL28 CIDEA CIDEC CLDN8 CLPSL2 CMTM7 CRACR2B CSN1S1 CX3CL1 ECHDC3 EGFLAM ELF5 ESYT1 ETV3L FABP4 FAH GABRP GSC GYG2 HCAR1 HEBP2 IGF1 IL17RD IL22RA2 IRX1 IRX2 IRX5 KIT LAMC2 LGALS12 LIPE LMX1B LTF MAP1LC3C MYEOV NFIB NMB OBP2B ORMDL3 OXTR PDGFRL PEMT PEX11A PLEKHS1 PLIN1 PLXDC1 PLXNA4 PNPLA2 PROM1 PTH2R PTHLH RAMP2 RDH5 RPL34 RPL39 RPL9 RPLP2 SCRN2 SCUBE2 SERPINF1 SFRP1 SLC19A3 SLC28A3 SLC5A6 STAC2 STAT5A TANK TFAP2B TFAP2C TIGD2 TIMP4 TMEM132C TNN TRPS1 VGLL1 VTCN1 Minor Salivary Gland Female 30-39 Up AGFG2 AMTN ANKRD36C APCDD1L AQP5 ASCL3 AZGP1 BACE2 BIK BPIFB2 C6ORF58 CAPN9 CCDC15 CCDC160 CCL28 CEP41 CES5A CHPT1 CHST9 CRACR2A CRACR2B CREB3L1 CREB3L4 CRISP3 CYB561 DEFB1 EHF ELF5 ENTPD3 FAM3D FBN3 FDCSP FOLR1 FUT2 FUT6 GALNT3 GALNT4 GALNT6 GALNT7 GCNT3 GDF5 GLYATL2 GNAS GOLM1 GPRC6A HTR3A KCNN4 KCTD14 KRT7 LPO LRRC26 LYZ MANSC1 MGAM2 MUC19 MUC5B MUC7 NAALADL2 NKX2-6 NXPE2 ODAM OTX1 PANX3 PHLDA1 PIGR PIP PLEKHS1 PLPP2 PROM1 PRR27 PRR4 PTH2R RAD51B RHD RNASE8 SH3BP4 SLC37A2 SLC44A3 SLC6A14 SLITRK6 SLPI SOX9 SPDEF SPINK14 SPINK8 STATH STK39 SVOPL TCN1 TMED3 TMEM200C TMEM63A TNFRSF11A TNFSF10 TOX3 TRPV4 WFDC2 XBP1 ZG16B ZNF552 Vagina Female 30-39 Up ADAMTSL5 ALOX12 BDKRB2 CLDN17 CPA6 DHRS2 DSC2 DSG3 EDN3 EHF ESR1 EVX1 FABP5 FAM110C FGFBP1 FOXQ1 GJB2 GJB6 GM2A HCG22 HES2 HOXA13 HOXD10 HOXD11 HOXD12 HOXD13 HPGD ISL1 ISL2 IVL KLK10 KLK14 KRT16 KRT17 KRT6A LCE3A LCE3D LCE3E MASP1 MAST4 MPZL2 NKX1-2 PGLYRP4 PI3 PLD2 PRDM1 PRPH PRRG4 PRSS12 S100A7 SALL3 SERPINB12 SERPINB13 SERPINB3 SERPINB4 SNX31 SOX7 SPINK6 SPRR1A SPRR1B SPRR2B SPRR2E SULT1E1 THSD4 TMPRSS11A TMPRSS11D TMPRSS11E TMPRSS11F UPK1A UPK2 VGLL1 VIP Skin - Not Sun Exposed (Suprapubic) Female 30-39 Up AADACL2 ABCA12 ABHD12B ACAD9 ACER1 ADGRF4 AHNAK2 ALOX12B ALOXE3 ARSF ATP6V1C2 BLMH BNIPL BPIFC C1ORF74 C3ORF52 CALML5 CARD18 CDHR1 CDX4 CERS3 CHP2 CLDN1 COL17A1 COL7A1 CPA4 CST6 CTSV DNASE1L2 ELOVL4 EPHX3 FGFR3 FLG2 GAN GJB3 GJB4 GPRIN2 HOPX HR IFFO2 IL20RA IL20RB KCNJ18 KCNK7 KLF4 KRT77 KRT80 KRTAP4-8 KRTAP5-10 KRTAP5-11 KRTAP5-8 KRTAP9-1 KRTAP9-6 KRTAP9-7 KRTDAP KY LAMB4 LGALS7B LGALSL LIPK LIPM LIPN LRIT2 LY6G6C LYPD5 LYPD6B MFSD2A NIPAL4 NKPD1 OR5P2 OVCH2 OVOL1 PKP1 PLA2G2F PLA2G4F PNPLA1 POU2F3 PPP1R14C RORA SDR9C7 SERPINB5 SLC10A6 SLC46A2 SPINT3 SPTLC3 SPTSSB TAS1R2 TCHHL1 TET3 TMPRSS13 TNS4 TREX2 UGT3A2 WEE1 WFDC5 WNT16 XCR1 XG XKRX ZNF273 Skin - Sun Exposed (Lower Leg) Female 30-39 Up AADACL2 ABCA12 ABHD12B ACER1 ADGRF2 ADGRF4 ALOX12B ALOXE3 ANKRD35 ANXA9 ASPRV1 ATP6V1C2 BLMH BNIPL BPIFC C1ORF68 C3ORF52 CALML5 CASP14 CDSN CHRNA9 CPA4 CTNNBIP1 CYP4F22 DLX3 DLX5 DMKN DSC1 DSG1 ELOVL4 EPHX3 FAM110A FGF22 FLG FLG2 GAN GJB4 GSDMA HOPX HS3ST6 IDE IFFO2 IGFL3 IL20RA IL36B IL36RN IL37 KLK5 KLK9 KPRP KRT23 KRT80 KRTDAP LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE4A LCE5A LCE6A LIPK LIPM LY6G6C LYPD5 NLRP10 OR10A3 PLA2G2F PLA2G4F PNPLA1 POF1B PSAPL1 RORA SBSN SDR9C7 SERPINA12 SERPINB12 SERPINB7 SLC37A2 SLC39A2 SLC46A2 SPTLC3 TGM5 THEM5 TINCR TMEM86A TMPRSS13 TREX2 TRPM1 TUFT1 UNC93A WFDC5 XCR1 XG XKRX Adipose - Subcutaneous Female 30-39 Up ABCD2 ABHD15 ACACB ACO1 ACVR1C ADAMTS5 ADGRF5 ADGRL4 ADH1B ADIPOQ AFAP1L1 AGPAT2 AGTR1 AIFM2 APOL6 AQP7 ARHGAP20 BMP6 BTNL9 C19ORF12 CAT CD300LG CD36 CIDEA CIDEC CPM CSAD DOCK11 EBF1 EBF3 ECHDC1 EGFL6 EIF4EBP2 ELMOD3 ERV3-1 FABP4 FAH FAM124B FZD4 GABRE GALNT15 GHR GPATCH11 GPD1 GPR146 GYG2 HEBP2 HNMT HTRA4 IGFBP3 ITGB1BP1 ITIH5 KLB LEP LIPA LIPE LPL LVRN MAN1A1 MEOX1 MYEOV NMT2 NPY5R NR1H3 NXNL1 PALMD PDE3B PEX19 PKD1L2 PLIN1 PLIN4 PLXNA4 PNPLA2 PPARG PRKAR2B PTPRM RDH5 RETSAT RNF125 SASH1 SEMA3G SESTD1 SIGLEC1 SIK2 SIM1 SLC19A3 SMIM3 STAT5A SYNE3 TGFBR3 TIMP4 TLN2 TM4SF19 TMEM132C TNMD UVRAG VKORC1L1 ZBED3 ZNF117 ZNF366 Muscle - Skeletal Female 30-39 Up ADPRHL1 ADRM1 ADSL AIMP2 ALPK3 AMFR ASB12 ASB2 ASB5 ASB8 BCL2L13 BEST3 BIN1 BRF2 C19ORF47 CACNB1 CACNG1 CACNG6 CAND2 CFAP61 CHRNA1 CHRNB1 CLIP1 CLTCL1 CORO6 CYB5R1 DHRS7 DUSP13 EGLN1 EPS15L1 EYA4 FHL3 FLNC FXR2 GLRX IP6K3 JSRP1 KCMF1 KCNJ11 KEAP1 KLHL30 KLHL40 KPNA1 LBX1 LPIN1 MAPK12 MIOS MKNK2 MRLN MYH14 MYO18A MYO18B MYPN NEDD4 NFE2L1 NPLOC4 OBSCN OPTN OSBPL11 P2RX6 PCNT PDLIM3 PFKM PHKA1 PHTF2 POPDC3 PRKAG3 PROB1 PSMA7 PSMC1 PSMD11 PSMD14 PSMD2 PSMD3 PSMD4 PSMD8 RAD23A RAPSN RNF123 RPUSD4 RYR1 SLC22A5 SLC29A2 SOD2 SPTB SQSTM1 STAC3 STK25 SYPL2 TBX15 TMEM233 TRIM54 TRIM63 TRIM72 TTN UBAC1 UBFD1 USP54 UTP11 YBX3 Nerve - Tibial Female 30-39 Up AATK ABCA10 ABCA8 ADGRG2 ANGPTL7 APOD ARHGAP19 ARHGEF10 BIRC7 BMP8B C1QL1 CASKIN2 CDH19 CDO1 CHEK2 CLCN2 CLDN19 CLDN20 CNTF COL28A1 CYP4B1 DCLK3 DHH DRP2 EBF2 EGFL8 EHBP1 EPB41L2 EXTL1 FAM178B FGFBP2 FOXD1 FOXD2 FOXD3 GAS2L3 GJC3 GLI1 GNRH1 HSPA12A IGFBP6 IL17B IL9 INF2 ITGA6 ITGB8 KANK4 KCNK12 KIF19 KLRG2 LCTL LGI2 LGI4 MAPK8IP1 MATN3 MEOX2 MFAP5 MIA MPZ NCMAP NDRG1 NEK1 NGFR OR6B2 OR6B3 OTUD7B PAPLN PDGFRL PLEKHA4 PLLP PMP22 PRICKLE1 PROS1 PROSER2 PRRG3 PRX PTPDC1 PTPRU RTKN SBSPON SECISBP2L SEMA3B SEMA4C SEMA5A SFRP5 SHC4 SLC22A3 SLC25A48 SLC2A1 SMCO3 SORCS1 SPIN2A SPTBN5 ST6GALNAC2 TAX1BP3 THSD7A TMEM215 TMPRSS5 USP53 VIT WNT6 Artery - Tibial Female 30-39 Up ACKR3 ACTA2 ACTN4 ADARB1 ADGRL3 ALDH1B1 AMIGO2 ANGPTL1 ATL3 AVPR1A BCAM C11ORF96 C12ORF75 C1QTNF7 CCDC3 CDH6 CLIC4 CNTN4 COL14A1 COMP CPED1 CRLF1 CRTC3 CSRP2 CYBRD1 DIAPH2 DSTN EFHD1 ENDOD1 ENOX2 ESD FBXL3 FHL5 FOXC1 FOXC2 FOXN3 HES4 HEY2 HMCN2 HOXC11 HOXC12 ID2 JAG1 JAK2 JUNB KCNAB1 KLHL26 LMOD1 LPP MAP7D3 MBNL1 MCAM MPP7 MSRB3 MSX2 MUSTN1 NKD1 NOTCH3 NPY1R NPY5R NTF3 NTRK3 P2RX1 PARD3B PDK3 PLEKHG3 PPP1R14A PRELP PRKG1 RAP1A RASL12 RASSF3 RCAN2 RHOB RNF180 ROCK1 ROR1 SETBP1 SFRP2 SH3BGRL SHOX2 SMIM10 SMOC1 SORBS2 SPOPL STS SYTL2 TAGLN TASP1 TBX18 TBXA2R TMEM181 TMEM47 TNS1 TOB1 TRABD2B TSC22D1 UBA2 WTIP ZFHX3 Whole Blood Male 20-29 Up ABTB1 AGTRAP ALOX5AP ALPL AQP9 ARHGAP30 ARHGAP9 ARHGDIB ARL11 BIN2 BST1 C16ORF54 C19ORF38 C1ORF162 CD300LF CD53 CDA CEACAM3 CEACAM4 CFP CKLF CLEC12A CLEC4A CLEC4E COTL1 CPPED1 CSF3R DPEP2 EFHD2 EVI2B FCER1G FGR FPR1 FRAT1 FRAT2 GAPT GCA GLIPR2 GLT1D1 GMFG GPR141 GPSM3 HCK ICAM3 IGSF6 IL17RA IL1R2 ITGAM ITGB2 JAML LAPTM5 LILRA1 LILRA2 LILRA5 LILRA6 LRRC25 LST1 MCEMP1 MNDA MSRB1 MYD88 NCF1 NCF2 NCF4 NFAM1 NFE2 NLRC4 NLRP12 OSCAR P2RY13 PILRA PLBD1 PPM1M PRAM1 PSTPIP1 PTAFR PYGL RASGRP4 RFLNB RGS19 S100A12 S100A9 S1PR4 SELL SELPLG SIGLEC10 SIGLEC5 SIGLEC9 SIRPB2 SPI1 STXBP2 TBXAS1 TLR5 TLR8 TNFAIP8L2 TYROBP VNN1 VNN2 VSIR VSTM1 Artery - Aorta Male 20-29 Up ADAMTSL3 ADRA1B ADRA1D ADRA2C AEBP1 ANKH ANO1 AQP1 BGN C1QTNF2 CD151 CLIC4 CNTN4 COL14A1 COL18A1 COL21A1 CRISPLD1 CYB5R3 EFEMP1 ELN ERG EXT1 FAM180A FBLIM1 FBLN5 FGL2 FIBIN FILIP1L FOXC1 FOXC2 GABRR1 GALNT2 GDF7 GLIPR1 HAPLN1 HAPLN3 HMCN1 IGFBP7 IL13RA2 IL31RA ITGA10 ITGA11 ITGA8 ITGA9 ITGB3 KALRN KANK1 KCNK17 KLHL42 LDOC1 LGR6 LIMS4 LMCD1 LOXL1 LRRC8A LTBP1 LTBP2 LTBP3 MFAP4 MFGE8 MGP MICAL2 MMP23B MRAP2 MYH10 MYH9 MYO1D MYOCD NAV2 NPR1 NTN1 NXPH3 OGN OSR1 PCDH7 PCDHB11 PID1 PKD2 PLD5 PLS3 PMEPA1 PRDM16 PRDM6 PRKG1 PRRX2 PTGIR PXDC1 RGS3 SCUBE3 SLC22A3 SMOC2 SOD3 SPARCL1 ST6GAL2 SULF1 TBXA2R TC2N TPH1 WWP2 ZNF385D Adipose - Visceral (Omentum) Male 20-29 Up ACVR1C ADAMTS1 ADAMTS15 ADAMTS4 ADAMTS9 ADIPOQ ALDH1A3 APOL4 ATP1B3 BDKRB2 C2ORF66 CCDC71L CCL2 CCL8 CCNL1 CD93 CDC42EP2 CDC42EP4 CDKN1A CDKN2C CH25H CIDEA CPSF4L CRISPLD2 CSRNP1 CTSL CXCL2 CXCL3 CYB5D1 DCUN1D3 DDX21 DGAT2 DLC1 DUSP6 EGR3 FABP4 FAM110D FAM89A FASN FOSB FOSL1 FOSL2 G0S2 GFPT2 GGCT GHR GPBAR1 GPD1 GPR4 HAS1 ICAM1 IGF1 IL1R1 IL6 KDM6B LGALS12 LIF LPL MAP3K8 MCL1 MEDAG MEST MMP19 MT1A MT1E MT1M MYC NFIL3 NMB NOCT NR4A3 NWD2 OR2B11 OR52N1 OR52N5 PIM1 PLAU PNP PNPLA2 PPARG PPP1R15B PPRC1 PRKAR2B RDH10 SELE SERTAD1 SLC25A25 SLC7A10 SNAI1 SOCS3 SOX17 SOX18 SPSB1 THBD TIMP4 TM4SF1 TMEM132C TMEM88 TRIB1 UAP1 Esophagus - Gastroesophageal Junction Male 20-29 Up AARD ACTG2 ACTN1 ADCY5 ADH5 ANKS1A ANTXR2 ARHGAP10 ARMC9 ATL2 BARX1 BCHE BTC CACNA1H CACNB2 CALD1 CHRM3 CNTNAP3B COL4A5 COL4A6 CSRP1 CST5 CYSLTR1 DAAM2 DGKG DNAH11 DPYSL3 EML1 EPHA7 FAM83D FBXO30 FGL2 FLNA FNBP1 FOXF1 FOXF2 FOXP1 GPC4 GRPR HDAC9 HLF HOXA3 HOXA4 HOXB3 HOXB4 HPSE2 INPP5A KANK2 KCNMA1 KCNMB1 KCNQ4 KLHL42 LMOD1 LSM11 MAGEB17 MAP3K20 MEIS1 MRGPRF MYH11 MYL9 MYLK MYOC NKX6-1 NRP2 NTN1 OCRL PALLD PARVA PCDH7 PDZRN3 PGM5 PLEKHO1 PPP1R12A PRDM8 PRUNE2 RAP1A RBPMS RGMB ROR2 RSPO2 RSPO3 S1PR3 SCUBE1 SEMA3A SEMA3E SLC2A12 SLITRK3 SMTN SORBS1 STON1 SYNM TACR2 TAF9B TEAD3 TOX2 TRPC6 TTC23 WLS WWTR1 ZNF503 Minor Salivary Gland Male 20-29 Up AGFG2 ALX1 AMTN ANKRD36C APCDD1L AQP5 AZGP1 B3GNT3 BACE2 BIK BPIFB2 C4ORF19 CAPN9 CATSPERB CCDC160 CCL28 CHPT1 CHST9 CNMD CRACR2A CRACR2B CREB3L1 CRISP3 DEFB1 DNASE2B DUSP23 EHF ELF5 ENPP3 ERN2 FAM3D FBN3 FDCSP FUT2 GALNT4 GALNT6 GDF5 GLYATL2 GOLM1 GPRC6A HTR3A KCNN4 KRT23 KRT7 LHX8 LPO LRRC26 LYZ MACC1 MANSC1 MGAM2 MLPH MMP12 MMP7 MUC19 MUC5B MUC7 NAALADL2 NKX2-6 NXPE2 ODAM OTX1 PIGR PIP PLEKHS1 PLPP2 PROM1 PRR27 PTH2R RHD RUNX1 SERINC2 SH3BP4 SLC28A3 SLC6A14 SLFN13 SLITRK6 SLPI SMR3A SMR3B SOX4 SOX9 SPDEF TCN1 TGFB2 TIGD2 TMC5 TMED3 TMEM200C TMEM63A TNFRSF11A TNFSF10 TOX3 TRPV4 VTCN1 WFDC2 WWC1 ZG16B ZNF552 ZSWIM4 Adipose - Subcutaneous Male 20-29 Up ABHD15 ACACB ACER2 ACO1 ACVR1C ADAMTS5 ADGRL4 ADH1B ADIPOQ ADRA2A AFAP1L1 AGPAT2 AGTR1 AIFM2 AKR1C2 ANGPTL4 APOL6 AQP7 ARHGAP20 AVPR2 BMP6 BNIP3L BTNL9 C19ORF12 CAT CD300LG CD36 CEBPA CFD CIDEA CIDEC CPM DOCK11 DTX1 EBF3 EIF4EBP2 ELMOD3 ESYT1 FABP4 FADS1 FAM124B FAM89A FASN FZD4 G0S2 GABRE GALNT15 GHR GPAM GPD1 GPIHBP1 GPR146 HEBP2 INHBB ITIH5 KLB LGALS12 LIPE LPL LVRN MEOX1 MEST MGST1 MOCS1 MYEOV NMT2 ORMDL3 PDE3B PEMT PEX11A PLIN1 PLIN4 PLXNA4 PNPLA2 PPARG PRKAR2B PRRT4 PTGER3 RBP7 RETSAT RNF125 S1PR1 SCD SEMA3G SIK2 SLC19A3 SMIM3 SPAAR SRPX SRPX2 STAT5A SYNE3 TIE1 TIMP4 TMEM132C TNMD UVRAG VKORC1L1 WNT11 ZBED3 Cells - EBV-transformed Lymphocytes Male 20-29 Up ADGRG5 AGPAT5 AHRR AICDA ANGPTL6 AP1S3 APOBEC3H ATAD5 B3GNT2 BATF BCL2 BLNK BTLA C17ORF99 CCL22 CCNI2 CCR7 CD226 CD274 CD40 CD48 CD70 CD79A CD80 CLEC17A CLEC2D CLNK CPOX E2F7 EBI3 EDEM1 ETV3L FAM72B FAM72D FCER2 FCRLA FSBP GCSAM GNGT2 GPR15 HLA-DOA HLA-DPA1 HLA-DQA1 HLA-DQA2 HLA-DQB1 HLA-DRA HMX3 HVCN1 IFIH1 IKZF2 IL12RB2 IL21R IL23R IL4I1 IRF4 IRF5 LTA LY75 MCM2 MCOLN2 MEF2B MYL12BP2 NCR2 NEK6 NFKBIE OAS2 OR5K3 P2RY10 PAX5 PIF1 PIK3R6 PMAIP1 PNOC POU2AF1 RAD54B RGS1 SCIMP SKAP1 SLAMF1 SLAMF6 SLAMF7 SPN TCL1A TEC TIFA TLR10 TLR7 TMSB15B TNF TNFRSF13B TNFRSF17 TNFRSF8 TNFSF9 TRAF1 TSPAN33 VASH2 WDFY4 WNT10A ZC3H12C ZNF318 Colon - Sigmoid Male 20-29 Up ABL1 ACOD1 ACTG2 ARRDC4 ATP2B4 BAG2 BCHE BMP3 BMPR1A BTC BTG2 CACNA1C CACNA1H CCL11 CDK8 CHRM2 COL24A1 DCHS1 DCHS2 EMILIN1 EML1 EPHA7 FOXF1 FOXP2 FZD7 GALR2 GDNF GJC1 GLB1L2 GLI3 GLP2R GREM2 HAND1 HAND2 HDAC4 HEPH HMCN2 HOXA13 HOXB3 HOXD11 HOXD13 HRH1 INAFM2 KCNMA1 KCNQ4 KIZ KLF10 KLHL23 KLHL5 LIMS2 LRIG1 LRRC3 MAB21L2 MAP3K14 MASP1 MDM1 METTL24 MFHAS1 MID1 MLXIP MRGPRD MYLK MYOCD NKX2-3 NKX3-2 NPPC NPY4R NT5DC3 NTSR1 NXN PDE3B PDE9A PDZRN3 PGM5 PHLDB2 PHOX2B PLA2G2C PLA2G4A PTBP2 PTGFRN PTGS1 QRFP RAB23 RNF150 ROR2 SEMA3A STON1 STON1-GTF2A1L SYDE2 TACR2 TBC1D1 TEAD3 TES TMEM252 TMTC2 TNFAIP8L1 TSPAN2 UBXN10 VIP WNT9A Heart - Left Ventricle Male 20-29 Up ACTC1 ADRB1 AIFM1 ANKRD1 BZW2 CASQ2 CDH2 CKMT2 COX5A COX7B CPT1B CRYAB CSDC2 CSRP3 CYC1 CYCS CYP2J2 DDO DECR1 DIRAS1 DLD EIF1AY ETFDH FABP3 FHL2 FHOD3 FITM2 GJA3 GOT1 GOT2 HADHB HHATL HRC HSPB7 IDH2 IGSF5 ITGB1BP2 KLHL31 LAPTM4B LARGE1 LDHB LSMEM2 MAPKAPK3 MDH1 MFN2 MLYCD MPC1 MRPS36 MYBPC3 MYL2 MYL3 MYOZ2 MYZAP NDUFA9 NDUFAB1 NDUFS1 NEBL NKX2-5 NMRK2 NNT NUDT4 OGDH OXCT1 PDHA1 PDHX PDLIM5 PKP2 PLN POPDC2 PTDSS1 PVR RD3L RYR2 S100A1 SCN5A SDHA SGCG SLC16A7 SLC25A3 SLC25A30 SLC25A4 SLC38A8 SLC4A3 SLC8A1 SMPX SMYD2 SRL ST3GAL6 TECRL TENM2 TNNI3 TNNI3K TNNT2 TPM1 UNC45B UQCRC1 UQCRC2 XIRP1 XPR1 ZNF330 Heart - Atrial Appendage Male 20-29 Up ACTC1 ADAMTS7 ADGRD1 ALPK2 ANKRD1 ASPG ATP2A2 BCO2 BMP10 C1ORF105 C6 CASQ2 CCDC141 CHRNE CIB2 CLGN CORIN CRIP2 CSDC2 CSRP3 CYCS CYSLTR2 DAND5 DHRS7C DHRS9 DKK3 EIF1AY EIF1B FABP3 FITM2 GATA4 GJA3 GJD2 GRXCR2 HCN4 HHATL HSPB3 IDH3A IGSF5 ITGB1BP2 KCNIP2 KLHL31 LAPTM4B LMOD2 LPAR3 LRRC10 MDH1 METTL7B MGAT5 MT1HL1 MTUS2 MYBPC3 MYBPHL MYH6 MYL4 MYL7 MYLK3 MYOZ2 MYZAP NDUFAB1 NEBL NES NKX2-5 NMRK2 NPPA NRTN NTN1 OR10P1 OTOGL PAM PDHA1 PKP2 PLA2G5 PLCXD3 POPDC2 PRKAG2 PXDNL RABGAP1L RBM20 RBPMS2 RD3L RILPL1 RYR2 SBK2 SBK3 SCN5A SHD SLC4A3 SLC8A1 SMPX SYNPO2L TBX20 TBX5 TECRL TMEM182 TNNT2 TRIM55 UQCRB VWDE XIRP1 Artery - Coronary Male 20-29 Up ACTA2 ACTN1 ADAMTS15 ADAMTS8 ADAMTS9 AEBP1 ANTXR1 AOC3 ARL4AP5 ARTN ATP10A BACE2 BGN BMP1 C1QTNF1 CCDC3 CD151 CHST3 CHSY1 CLIC4 CMKLR1 COL15A1 COL18A1 COL4A1 COL4A2 CTPS1 EDNRA ELN ENPP4 EPAS1 EPHA8 FBLIM1 FMOD FRK FSTL3 GALNT2 GJA5 GLIS2 HAPLN1 HEYL HTR1B ID4 IGFBP7 IL33 INHBA ITGB3 JADE1 JAG1 KCNK15 KCTD10 LGR6 LTBP1 MCAM MEDAG MFAP4 MFGE8 MICAL2 MSC MTHFD1L MTHFD2 MYBL1 NT5DC2 NTF3 NUDT4 OGN PAWR PCSK7 PDE3A PDGFA PLA2G5 PLPP1 PPP1R14A PTGIS RASL11A S1PR3 SH3RF3 SPRY4 SULF1 TAGLN TBX18 TBXA2R TEX2 TGM2 THBS2 TIMP1 TNC TNFAIP8L3 TNFRSF11B TRABD2B TRPC4 VCAN WFDC1 ZFHX3 Liver Male 20-29 Up A1BG AHSG AKR1C1 ALB AMBP ANKRD33 APOA2 APOB APOC1 APOC2 APOH APOM ASGR2 ASL ASS1 C4A C4B C4BPA C4BPB C8G CA5A CES1 CFB CLDN2 CP CPN1 CPN2 CPS1 CREB3L3 CRP CRYBA4 CTH CYP2E1 CYP4F11 DCXR DHODH DNMT3L EVA1A F2 FCN2 FGA FGB FGF19 FGG FURIN GALNT2 GC GCH1 GDF2 GK GRAMD4 HGD HPD HPX HS3ST3B1 HSD17B2 HYOU1 IFNK IGFALS IGFBP1 ITIH1 ITIH2 ITIH3 ITIH4 KPNA7 KYNU LBP LRG1 MASP2 METTL7B MMP10 NAGS NOTUM NPC1L1 OIT3 ORM1 PLGLB2 PON3 PRG4 RBP4 RND1 RPRD1B SDS SDSL SERPINA1 SERPINA10 SERPINA2 SERPINA3 SLC13A5 SLC17A9 SLC25A15 SLC27A2 SLC35C1 SLC5A6 TF THPO TRIM40 TTR UGT1A3 VTN Artery - Tibial Male 20-29 Up ACTA2 ACTN4 ADARB1 ADIRF ALDH1B1 AMIGO2 ANGPTL1 ATL3 AVPR1A C11ORF96 C1QTNF7 CDH6 CLIC4 CNTN4 COL14A1 COL18A1 CPED1 CRLF1 CRTC3 CSPG4 CSRP1 CSRP2 DACT3 DSTN EFHD1 ENDOD1 ENOX2 ESD FBXL3 FERMT2 FHL5 FOXC1 FOXC2 FRY HEY2 HRCT1 HTR1B ID2 ITGA5 ITPR1 JAG1 JAK2 KCNAB1 KCTD10 KLHL26 LMOD1 LPP MAP7D3 MBNL1 MCAM MSRB3 MTHFD2 MUSTN1 MYBL1 NKD1 NOTCH3 NTF3 NTRK3 P2RX1 PCSK7 PDK3 PITPNB PLEKHG3 PPP1R14A PRKG1 PTK2 RAB23 RAP1A RASL12 RASSF3 RHOB RNF180 ROCK1 ROR1 RSU1 SBDS SDK1 SH3BGRL SH3RF3 SMIM10 SMURF1 SOBP SORBS1 SORBS2 SPOPL SSBP3 STS TAGLN TASP1 TBX18 TBXA2R TGM2 TLN1 TMEM181 TNC TNS1 TRABD2B UBA2 WDR1 ZFHX3 Brain - Amygdala Female 60-69 Up ADCY8 AMELX AMZ1 APC AQP4 BCAN C1QL1 C1QL2 CAMK2N1 CDH20 CDH4 CPNE6 CRB2 CSAG1 CSPG5 CTNNA2 CTNND2 CXCL11 DEAF1 DLL3 DOK6 DSCAM ELFN2 ETNPPL FAM107A FAM181B FBXO2 FEZF2 FRG2 FRG2B FRG2C GPM6A GSX2 HIPK2 HSD11B1L KDM4F KIF5A KIF5C LHFPL3 LIX1 LUZP2 LY6H MAPK8IP2 MBD3L2 MEIS3 MLC1 MT3 MYRIP NANOS3 NCAM2 NCS1 NECAB2 NPAS3 NR2E1 NTRK2 OCM OLIG1 OLIG2 OPALIN OR5AU1 PAIP2B PCDH15 PHACTR3 PRAMEF2 PRAMEF25 PRAMEF27 PRAMEF7 PRAMEF8 PRR20E PTPRZ1 RAPGEF4 RASL10A RFPL4A RFPL4AL1 RNASE10 RTP5 SCD5 SFXN5 SHTN1 SLC25A18 SLC38A8 SLCO1A2 STON2 STOX1 STUM SYTL5 TFAP2D TNR TRIM43 TRIM43B TRIM49 TRIM49B TRIM49C TRIM49D1 TTC9B UCMA UNC13C USP17L2 USP17L7 ZSCAN5C Kidney - Cortex Female 60-69 Up ACMSD ACY3 AGMAT AGXT2 AMACR AQP2 AQP6 ATP6V0A4 ATP6V0D2 ATP6V1G3 BBOX1 BSND C11ORF54 CDH16 CLCNKB CLDN16 CLDN2 CLEC18B CLEC18C CRYL1 CUBN CYP24A1 CYP27B1 CYS1 DCDC2 DEFB1 DMRT2 DUSP9 EMX1 FCAMR FMO1 FOXI1 FOXI2 FXYD2 FXYD4 GGT1 HAVCR1 HNF1B IL17RB KCNJ1 KCP KIF12 KL LRP2 LYG1 MCCD1 MIOX MUC20 NAT8 NPHS1 NPHS2 OGDHL PAPPA2 PAQR5 PAX2 PDZK1 PDZK1IP1 PKHD1 PRODH2 PTH1R PTH2R RBP5 REN SLC12A1 SLC12A3 SLC13A1 SLC13A3 SLC16A4 SLC17A1 SLC17A3 SLC22A11 SLC22A12 SLC22A13 SLC22A2 SLC22A6 SLC22A8 SLC34A1 SLC34A3 SLC3A1 SLC47A2 SLC4A9 SLC5A10 SLC5A12 SLC5A2 SLC6A13 SPP1 TINAG TMEM101 TMEM174 TMEM213 TMEM252 TMEM52B TMEM72 TRPV5 UGT1A9 UGT2B7 UMOD UNC5CL UPP2 WFDC2 Cells - Cultured Fibroblasts Female 40-49 Up ABL2 ADAM12 ADAM9 ADAMTS6 ALDH1L2 ARSJ ASCC3 BRIX1 C6ORF120 CALU CCBE1 CD109 CHAMP1 CHML CITED2 CKAP4 CLEC11A COA7 COL12A1 COL1A2 COL5A2 COL6A3 CUL4B CXCL5 DCBLD2 DKK1 DSEL DUSP10 EDA2R EIF2AK4 EMC1 FAP FBN1 FBN2 FKBP10 FKBP14 FN1 FRMD6 GNPNAT1 GPR176 GPX8 HMGA2 HOXC8 HS3ST3A1 HS3ST3B1 IGF2BP2 IGF2BP3 IKBIP KCNK2 KDELR3 LOX LOXL2 LRP12 MME MMP1 MMP14 MSANTD3 NECTIN3 NT5E PAPPA PCDH18 PCDHGA11 PCDHGA12 PCDHGB4 PCOLCE PLOD2 PLOD3 PRIM2 PRKDC PRR16 PTX3 RCN1 RCN3 RECK RUNX2 SEC22B SLC35B2 SMG8 SNAI2 SNAPC1 SRGAP1 STEAP1 STEAP1B TNFRSF10D TNPO1 TPBG TRAM1 TRAM2 TRIAP1 TRNP1 TRPA1 TWIST1 TWIST2 ULBP1 ULBP3 VASN VGLL3 WNT5A XPOT ZNF281 Brain - Hippocampus Female 40-49 Up ADRA1D AGAP2 AK5 ANKRD66 APC ATP1A3 ATP6V0E2 B3GAT1 B3GAT2 BCAS4 BHLHE22 BTBD3 C1QL2 C7ORF57 CABP7 CACNG8 CAMK2A CARMIL2 CHCHD6 CNIH2 CNIH3 CPLX2 CPNE4 CPNE6 DCDC1 DEAF1 DGKZ DLG2 DLGAP3 DOK6 ENC1 EPHA5 FEZF2 FGF13 FIBCD1 FOXD4L3 FOXD4L6 GABRA5 GRIA1 GRIN2B HHIP HRK HS6ST3 HTR1A ICAM5 IDS JPH3 KCNG2 KCNJ6 KCNK4 KCNMB2 KCNN1 KLHL2 LINGO1 LY6H LYNX1 MAP3K10 MAS1 MFRP MMP17 NCS1 NELL2 NEUROD6 NEUROG3 NOS1AP NPTXR NRIP3 NSMF PCDH20 PCDH8 PFN2 PGBD5 PIK3R2 PLPPR2 PLPPR4 PPM1E PPP1R9B PRKCA PRKCG PSD RFK RTP5 SCN3B SEMA6B SEZ6L SHANK1 SHISA6 SLC17A7 SLC24A3 SLC25A23 SMIM10L2A ST6GALNAC5 STOML3 STUM SUSD4 SYT17 TMEFF1 TRHDE WASF1 WIPF3 Brain - Substantia Nigra Female 40-49 Up ANKRD40 ANLN APLP1 BACE1 BCAS1 CA14 CARNS1 CDK18 CHADL CHRM5 CHRNB3 CHST6 CLDND1 CMTM5 CNDP1 CNP CNTN2 CNTNAP4 CTNNA3 DBNDD2 DNER DPYSL5 DYNC1LI2 ENPP6 ERMN FEZ1 FGF1 FMNL2 FOXB1 GJC2 GPR37 HAPLN2 HIPK2 HOXD1 KCNE5 KCNJ10 KIF6 KLHL1 KLK6 LHPP LLGL1 LPAR1 LUZP2 MAG MARCKSL1 MBP MFRP MKRN3 MOBP MOG MRGPRE MTURN MVB12B NDST4 NIPA1 NKAIN2 NKX2-2 NKX6-2 OLIG1 PAIP2B PAQR6 PAQR8 PCSK6 PEX5L PIP4K2A PKP4 PLEKHB1 PLP1 POU4F2 PRRG1 QDPR RASSF2 RFTN2 RND2 RNF141 RPE65 S100B SEC14L5 SEMA4D SHTN1 SLAIN1 SLC10A4 SLC5A11 SLC6A11 SLC6A3 SLCO1A2 SPOCK3 STMN4 SYNJ2 TBC1D12 TMEM144 TMEM229A TP53INP2 TRAK2 TRIL TRIM41 TSC22D4 TTYH2 UGT8 ZNF488 Brain - Anterior Cingulate Cortex (BA24) Female 40-49 Up ADCY2 APC ARL6IP1 ASIC2 C1QL3 CA11 CACNG3 CAMK2A CAMK2N1 CCK CHN1 CLEC2L CNIH3 CREG2 CTNNA2 CTNND2 DEAF1 DOK6 DRD5 ELFN2 ENC1 ERC2 FAM107A FAM163B FAM171B FAM81A FEZF2 FXYD7 GABBR2 GABRA2 GABRA3 GAP43 GDA GNG3 GPM6A GRIN3A HRK HSD11B1L HTR2A IDS KCNC2 KCNN1 KCNV1 KCTD16 KIF5A LHX2 LIMK1 LINGO1 MAP1A MAP2 MAPK8IP2 MEIS3 MPPED1 MYRIP NANOS3 NAPB NEUROD6 NKAIN4 NPTXR NRCAM NRG3 NRSN1 NTRK2 OLFM1 OR14I1 PACSIN1 PGM2L1 PHF24 PTER RAB6B RAPGEF4 RGS4 RNF182 RXFP1 SCN3B SERPINI1 SHANK1 SHC3 SLC17A7 SLC1A2 SLC1A3 SLC35F1 SLC39A12 SLIT1 SLITRK1 SMIM10L2A SMIM10L2B SNCA STUM STX1A SYN1 SYN2 SYT1 SYT17 TAGLN3 TFPT TMEM132D TSPOAP1 WSB2 YWHAH Brain - Caudate (Basal Ganglia) Female 40-49 Up ACBD7 ADORA2A ANKRD34B ANO3 AQP4 ARNT2 ARPP21 BCAN C1ORF87 CABLES1 CACNG4 CFAP157 CFAP73 CHI3L2 CHRM4 CNMD CRB1 CRB2 CTXN1 CYP46A1 DACT2 DGKB DLX6 DNAH9 DRD1 DYDC2 ENHO ENKUR ETNPPL FAM171A1 FAM171B FBXL16 FRMPD2 GABRG1 GAREM2 GNAL GNG7 GPC5 GPR139 GPR37L1 GPR6 GPR75 GPR85 GPR88 GRM3 HAGHL HEPACAM HHIPL1 HPCA HS3ST5 IQCA1 JAKMIP1 KCNH4 KCTD17 KHDC1L KIAA2012 KLF16 LRRC10B LRTM2 MAPK4 MEGF10 METRN MINDY4B MLC1 MRO NCDN NR2E1 NTSR2 NWD1 OR12D2 PCP4 PCP4L1 PDE10A PDE1B POU3F2 POU3F4 PPP1R1B PPP3CA PSD2 PTPN5 RASD2 RGS14 RGS20 RGS8 RGS9 RSPH1 SCN4B SLC1A2 SLC25A23 SLC35D3 SLC6A1 SLC6A12 SNN SP9 SPAG8 SPEF1 STOML3 STON2 SYNDIG1L WDR49 Skin - Sun Exposed (Lower Leg) Female 40-49 Up AADACL2 ABCA12 ABHD12B ACER1 ADGRF2 ALOX12B ALOXE3 ASPRV1 BPIFC C1ORF68 C6ORF15 CALML5 CASP14 CASZ1 CDSN CTNNBIP1 CYP4F22 DEGS2 DLX3 DLX5 DMKN DSC1 DSG1 EFNA3 EPHB3 EPHX3 EPPK1 FAM110A FAM83G FGF22 FLG FLG2 GAN GJB3 GJB4 GSDMA HS3ST6 IDE IFFO2 IL36B IL36RN IL37 KLC3 KLK5 KLK7 KLK9 KLRF2 KPRP KRT10 KRT2 KRT23 KRT80 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE4A LCE5A LCE6A LIPM LY6G6C LYPD5 NIPAL4 NKPD1 NLRP10 PKP1 PLA2G4E PNPLA1 POF1B PSAPL1 RDH12 RNF39 RORA SBSN SDR9C7 SERPINA12 SERPINB12 SERPINB7 SERPINB8 SLC46A2 SPTLC3 TGM5 THEM5 TINCR TMEM45A TMEM86A TMPRSS13 TREX2 TUFT1 UNC93A WFDC5 XCR1 XG XKRX Adipose - Subcutaneous Female 40-49 Up ABHD15 ACACB ACO1 ACVR1C ADAMTS5 ADGRL4 ADH1B ADIPOQ ADRA2A AFAP1L1 AGPAT2 AGTR1 AIFM2 AKR1C2 ANGPTL2 APOL6 AQP7 ARHGAP20 ATP8B4 AVPR2 BNIP3L C19ORF12 CAT CD248 CD300LG CD36 CEBPA CFD CIDEA CIDEC CPM DEFB132 DOCK11 EBF1 EBF3 EGFL6 ELMOD3 ESYT1 FABP4 FAM89A FZD4 G0S2 GABRE GALNT15 GFRAL GHR GPBAR1 GPD1 GPR146 GYG2 HEBP2 INHBB ITGB1BP1 ITIH5 ITSN1 KLB LEP LGALS12 LIPE LPL LVRN MEOX1 MEST MGLL MGST1 NMT2 NXNL1 PALMD PDE3B PEX11A PHLDA3 PLIN1 PLIN4 PLXNA4 PNPLA2 PPARG PRKAR2B PTGER3 RDH5 RETSAT RNF125 SASH1 SEMA3G SIK2 SIM1 SLC19A3 SLC29A4 SLC7A10 SMIM3 SRPX2 STAT5A SYNE3 TIMP4 TLCD2 TMEM132C TNMD TSKU UVRAG VEGFB VKORC1L1 Muscle - Skeletal Female 40-49 Up ALPK3 AMPD3 ANKRD23 ASB12 ASB2 ASB8 BEST3 BIN1 BTBD1 CACNG6 CAND2 CAP2 CHMP1B CHRNB1 CKM CLIP1 CMYA5 COQ8A CSDE1 CYB5R1 DCAF6 DUSP13 EGLN1 EYA4 FBXO32 FEM1A FHL3 GMPR HDAC4 HECTD1 IDI2 IP6K3 JPH1 JSRP1 KCNA7 KCNJ11 KEAP1 KLHL30 KLHL41 LBX1 LINGO4 LPIN1 LRRC2 MAPK12 MKNK2 MRLN MYBPC1 MYO18A MYO18B MYPN NEB NEDD4 NFE2L1 NRAP OBSCN OPTN OSBPL11 P2RX6 PCNT PFKM PGPEP1L PHKA1 PITX3 POPDC3 PROB1 PYGM RAD23A RAPSN RNF123 RPUSD4 RYR1 SCN4A SIX4 SLC16A10 SLC22A5 SLC29A2 SMTNL1 SMTNL2 SPTB STAC3 SYPL2 TBX15 TMEM233 TMOD4 TNNT1 TPM3 TRDN TRIM54 TRIM63 TRIM72 TTN UBAC1 UBR3 UCP3 USO1 USP13 USP54 UTP11 YBX3 ZNF106 Cells - EBV-transformed Lymphocytes Female 40-49 Up ADGRG5 AICDA APOBEC3G ASF1B ATAD5 AURKB BFSP2 BLM BLNK BORA BRCA2 BTK BTLA CCL22 CCR8 CD226 CD70 CD79A CD80 CD86 CENPM CLEC17A CPOX CXCR3 DEPDC1B DNA2 DTL EAF2 EED ESCO2 FAM111B FAM72B FAM72C FAM72D FCER2 FCRLA FEN1 GINS2 GPR15 GPR55 HELLS HMX2 HMX3 HVCN1 IFI44L IKZF3 IL12B IL21R IRF4 IRF5 ITGA4 ITGB7 KLLN LMNB1 LTA MCM2 MCM3 MCM5 MCOLN2 MX1 MYBL2 MYL12BP2 NUP210 OAS2 ORC1 P2RY10 PAX5 PIF1 PIK3R6 PLCG2 PNOC POLQ POU2AF1 PUDP RAD54B RFC3 RRM2 SLAMF1 SLAMF7 SNX25 SPIB SPN STAT1 TCL1A TIFA TLR7 TNF TNFRSF13B TNFRSF17 TNFRSF8 TNFSF11 TNFSF9 TSPAN33 TTF2 USP18 VASH2 VRK2 WDFY4 XRCC2 ZWINT Whole Blood Female 40-49 Up ADAM8 ADGRE2 ADGRE3 ADGRG3 ALPL APOBEC3A APOBR AQP9 ARHGAP25 ARL11 BIN2 BST1 C16ORF54 C19ORF38 C5AR2 CEACAM3 CFP CSF2RB CSF3R CXCR1 CXCR2 CYTH4 DOK3 EVI2B FCGR2A FCGR3B FFAR2 FGD3 FPR1 FPR2 FRAT2 GLT1D1 GMIP GRK6 HCK ICAM3 IL17RA IL18RAP ITGAM ITGAX ITGB2 JAK3 JAML LILRA2 LILRA5 LILRA6 LILRB2 LILRB3 LPAR2 LRRC25 LYN MBOAT7 MEFV MMP25 MNDA MYD88 MYO1F NCF2 NCF4 NFAM1 NFE2 NLRP12 OSCAR P2RY13 PLXNC1 PROK2 PTAFR PTPRC R3HDM4 RASGRP4 REM2 RGS18 RGS19 RNF149 RPS6KA1 S1PR4 SECTM1 SELL SELPLG SHKBP1 SIGLEC5 SIRPB1 SIRPB2 SLA SLC12A9 SLC22A4 SLC25A37 SPI1 SRGN TAS2R40 TBXAS1 TLR1 TLR2 TMEM71 TNFRSF10C TNFSF13B VSIR WAS XPO6 ZDHHC18 Spleen Female 40-49 Up ABI3 ANXA2R BANK1 BLK BTN3A1 C1QA C1QB C1QC CABP4 CARD9 CCL14 CCL24 CCM2L CD163L1 CD180 CD19 CD1C CD1D CD22 CD33 CD4 CD5L CD72 CD79B CD8A CDCP2 CERKL CNR2 CR2 CSF1R CXCL13 CXCL6 CXCR5 DNASE1L3 EMID1 EXOC3L1 FAM9C FCGR3A FCMR FCRL1 FCRL2 FCRL3 FCRL5 FGD2 FHOD1 FLI1 GDPD2 GDPD5 GIMAP1 GPR182 GRAP HLA-DOB HMOX1 HYAL1 HYAL2 IL10RA IL24 IRF8 ITGAD LILRA4 LILRB1 LILRB5 LIPA LRTM1 LTB MFNG MPEG1 MS4A7 MZB1 NLRC3 NOS3 NOX5 NR5A1 NTN4 OR5AK2 OR9G4 P2RX5 P2RY6 PARP15 PDE2A PDE6G PLA2G2D PLA2G7 PSTPIP2 RENBP SIGLEC12 SPIC STAB1 STAB2 TAS1R3 TDGF1 TLX1 TMC8 TMEM156 TMEM26 TNFRSF13C TRAPPC3L TTC24 UNC93B1 VCAM1 Thyroid Female 40-49 Up ATP13A4 BMP8A C16ORF89 CLN5 COL23A1 CRYGN CYTH2 DAPK2 DIO1 DIO2 DUOX2 EPOR EXOC3L2 FOXE1 FREM2 FSCN2 GAL3ST3 GOLGA8M GOLGA8Q GOLGA8R GRK1 HHEX HIRA HOOK3 IFT140 IL15 INPP5J ISM1 IVD IYD KCNJ16 KLHL14 KNSTRN LCN12 LIPG LPCAT2 LRP2 LRP8 MARVELD2 MCIDAS MGAT4C MPPED2 MROH1 MSANTD2 MT1F MUC15 NKX2-1 NPNT OR2A1 OR2A42 OR2T8 PABPC1L PAX8 PBX4 PDE8B PKHD1L1 PLA2G6 PLA2R1 PLEKHG4B PLEKHH1 PLVAP PPP1R13B PRKX PRTG RASSF4 RCBTB1 RGL3 S100A5 SALL1 SALL4 SCX SEMA3D SHISA2 SLC12A8 SLC16A11 SLC25A29 SLC26A4 SLC26A7 SLC4A11 SLC5A8 SMAD9 SNX1 SNX22 SORD SUCNR1 TCERG1L TG TLE6 TMEM267 TMEM50B TPMT TPO TSHR WDR72 ZBED2 ZNF114 ZNF486 ZNF737 ZNF804B ZNF90 Stomach Female 40-49 Up A4GNT ADAM28 AGR2 AKR1B10 AKR7A3 ANKRD22 ANXA10 ARSD ATP4A ATP4B B3GNT3 B4GALNT3 BAIAP2L1 BARX1 C9ORF152 CA9 CAPN13 CAPN8 CAPN9 CCKAR CCKBR CHIA CLDN18 CLIC6 COL2A1 CTSE CXCL17 CYP2S1 CYSTM1 ERN2 ESRRG FER1L6 FMO5 FOXA2 FOXA3 FOXQ1 FRMD1 GALE GAST GATA5 GCNT4 GHRL GKN1 GKN2 GPER1 GPRC5C KCNE2 LIPF MCIDAS MECOM MFSD4A MUC1 MUC5AC MUC6 MYH13 NBPF12 ONECUT3 OSBPL7 PALM3 PDILT PGA3 PGA4 PGA5 PGC PIK3C2G PSCA RASSF6 RFLNA RFX6 SLC26A9 SLC41A2 SLC9A2 SLC9A4 SST SULT1C2 TFF1 TFF2 TMED6 TMEM92 TOX3 TPCN2 TRIM50 TRIM73 VSIG1 VSIG2 VWA2 XYLT2 ZFPM1 Pancreas Female 40-49 Up AKR7A3 AMY1B AMY1C AMY2A AMY2B ANXA4 AQP12A AQP12B AQP8 ASCL5 BHLHA15 BNIP3 CEL CELA2A CELA2B CELA3A CELA3B CFTR CLDN10 CLPS CLPSL1 CLPSL2 CPA1 CPA2 CPB1 CTRB1 CTRB2 CTRC CTRL CUZD1 CYP3A43 EPB41L4B ERICH5 ERO1B ERP27 FAM3B FBXW12 FKBP11 G6PC2 GATM GCG GLP1R GNMT GP2 GPHA2 GPR119 GPR150 GUCA1C HOMER2 IAPP IL22RA1 INS KCNK16 KIRREL2 KLK1 LENG9 LHFPL5 MNX1 NR5A2 ONECUT1 OR10G4 OR4D5 OR8D4 P4HB PDIA2 PDX1 PGGHG PKHD1 PLA2G1B PNLIP PNLIPRP1 PNLIPRP2 PRDX4 PRSS1 PRSS16 PRSS2 PRSS3 PTF1A RBPJL REG1A REG1B RNF186 SCTR SEL1L SERPINI2 SLC16A12 SLC30A2 SLC30A8 SLC38A5 SLC39A5 SLC43A1 SLC4A4 SPINK1 SPSB4 SYCN TECPR1 TMED6 TMEM97 TPST2 XBP1 Esophagus - Mucosa Female 40-49 Up A2ML1 ADH7 ALDH3A1 ANXA1 AQP3 CAPN14 CLCA2 CNFN CRABP2 CRNN CSTA CSTB CYSRT1 DSC2 DSG3 DYNAP ECM1 EHF EMP1 EPGN EPHA1 EPHA2 ERO1A ESPL1 FABP5 FAM83A FGFBP1 FUT6 GBP6 GJB2 GPR78 GRHL3 GSTP1 IL1RN IL36A KLK10 KLK13 KRT13 KRT15 KRT4 KRT6A KRT78 LEXM LY6D LYPD2 MALL MPZL2 MUC21 NMU OTOP3 PADI1 PAX9 PITX1 PPL PRSS22 PRSS27 RAB10 RAB25 RABGGTA RAET1E RAET1G RAET1L RHCG RIPK4 RNF223 S100A14 S100A16 S100A2 S100A8 SAMD9 SERPINB13 SERPINB2 SFN SIM2 SPINK5 SPRR1A SPRR2A SPRR2D SPRR3 TACSTD2 TGM1 TGM3 TMEM184A TMEM40 TMPRSS11A TMPRSS11B TMPRSS11D TMPRSS11E TMPRSS11F TMPRSS4 TRIM16 TTC22 TTC9 TXN TXNDC17 UGT1A7 USH1G VSIG10L ZDHHC13 ZNF185 Esophagus - Muscularis Female 40-49 Up ABCC1 ACTG2 ACTN1 ADCY5 ADH5 ANKS1A ANTXR2 ARHGAP10 ARMC9 ARSB BCHE BTC CACNA1H CACNB2 CALD1 CHRM3 CNTNAP3 COL4A5 COL4A6 CYSLTR1 DAAM2 DGKG DPYSL3 EML1 EPHA7 FAM83D FBXO30 FNBP1 FOXF2 FOXP1 GPC4 GRPR HLF HOXA4 HPSE2 HTR2B IGSF9B ITGA1 JPH2 KANK2 KCNMB1 KCNQ4 KIAA0753 KITLG LHCGR LPP LSM11 MYH11 MYL9 MYLK NKX6-1 NRP2 NTN1 PALLD PARVA PGM5 PLEKHO1 PPP1R12A PRUNE2 PYGB RARB RGMA RGMB RSPO3 S1PR3 SCUBE1 SEMA3A SEMA3E SGMS2 SLC27A6 SLC2A12 SLITRK3 SMTN SORBS1 STON1 SYDE2 SYNM SYNPO2 TPBG TRPC6 TTC23 WLS WWTR1 ZNF503 Vagina Female 40-49 Up A2ML1 ADAMTSL5 ALOX12 BARX2 BDKRB2 CDKN2B CLCA2 CLDN17 CNFN CPA6 CRABP2 CRCT1 DIO3 DKK4 DSC2 DSG3 EDN2 EDN3 EHF EPHA1 ESR1 EVPLL EVX1 FABP5 FAM83A GJB2 GJB6 GOLGA6L9 GPR87 GRHL1 HCG22 HES2 HOXA13 HOXD10 HOXD11 HOXD12 HOXD13 HPGD IL18 ISL1 ISL2 IVL KLK10 KLK11 KLK12 KRT13 KRT6A KRT6C LANCL3 LCE3A LCE3D LCE3E LPAR6 MAB21L3 MALL MASP1 MAST4 MPZL2 NOD2 NUAK2 PGLYRP3 PGLYRP4 PI3 PLA2G4D PPL PRRG4 PRSS12 RAET1E RHCG RNF223 RPTN RSPO1 SALL3 SERPINB12 SERPINB13 SERPINB3 SERPINB4 SLC18A2 SMAGP SOX7 SPINK5 SPINK6 SPINK7 SPRR1A SPRR1B SPRR3 SULT1E1 SULT2B1 THSD4 TMPRSS11A TMPRSS11D TMPRSS11E TMPRSS11F TP53AIP1 TPRG1 TRIM16 TTC22 UPK1A WFDC12 ZNF185 Esophagus - Gastroesophageal Junction Female 40-49 Up AARD ACTG2 ADCY5 ADH5 ANKS1A ANTXR2 ARHGAP10 BTC CACNA1H CACNB2 CHRM3 COL4A5 COL4A6 CYSLTR1 DGKG EML1 EPHA7 FBXO30 FGL2 FOXF1 FOXF2 GPC4 HOXA4 HOXB4 HPSE2 JPH2 KCNMB1 KCNQ4 KIAA0753 LSM11 MRGPRF MYH11 MYL9 MYLK NKX6-1 NRP2 NTN1 OCRL PALLD PGM5 PLEKHO1 PPP1R12A PRUNE2 RBPMS RGMB RSPO2 RSPO3 S1PR3 SEMA3A SEMA3E SLITRK3 SMTN SORBS1 SYNM TGFB1I1 WLS ZNF503 Ovary Female 40-49 Up ACSM3 ADAMTS16 ADRB3 AMHR2 ANGPTL5 ARX ASIP BAMBI BNC2 BST2 C21ORF62 C7 CCDC8 CDH11 CDH23 CDH3 CHST7 CLSTN2 COL16A1 COLEC11 CPZ DAPK1 DET1 ECEL1 EML5 ESR2 FFAR1 FKBP7 FOXL2 FOXL2NB GALNT10 GATA4 GATA6 GLI2 GREB1 GSTM5 HNRNPA1 HS3ST1 HS6ST2 IGDCC4 IGFBP5 IGSF10 KCNMB2 KLHDC8A LHX9 LPAR4 LRRC17 MCC MDK METAP1D MEX3A MMP21 MMP23B NFATC4 NLGN4X NR2F2 NRK NYNRIN OBSL1 PCDHGB6 PDGFRA PEG3 PRDM5 PROK1 PRPS2 PTK7 RASL11B RBP1 RPS8 SIGLEC11 SIGLEC16 SIMC1 SLC8B1 SNCAIP SOX4 ST13 SULF2 SULT1C4 SYTL4 TCEAL1 TCEAL4 TCF23 TDGF1 TDGF1P3 TENM4 TMEM221 TMEM98 TRABD2A TRIB2 TSHZ1 TSHZ3 TTC8 UBXN8 VLDLR VWCE WFIKKN2 WIPF3 WT1 ZNF556 ZNF66 Skin - Not Sun Exposed (Suprapubic) Female 40-49 Up AADACL2 ABCA12 ADGRF4 AHNAK2 ALOX12B ANXA8L1 ARSF ATP6V1C2 BPIFC C1ORF74 C3ORF52 CARD18 CASP14 CCL27 CD207 CDX4 CENPP CLDN1 COL17A1 COL7A1 CPA4 DCT DEGS1 DMKN DSC3 DSG1 DSP DUSP7 EPPK1 ETV3 EXPH5 FAM83B FAM83F GAL3ST4 GAN GATA3 GJB3 IFFO2 IL20RA IL20RB IRF6 KCNJ18 KCNK7 KLC3 KLF4 KREMEN2 KRT1 KRT14 KRT77 KRTDAP KY LAMB4 LGALS7 LGALSL LIPK LIPM LRIT2 LTB4R LYPD6B MFSD2A MLANA NIPAL4 NKPD1 OR5P2 OR5P3 OVCH2 PGLYRP4 PKP1 PLA2G4E PLA2G4F PNPLA1 POU2F3 RDH12 RORA SDR42E1 SERPINB12 SERPINB5 SERPINB7 SLC10A6 SLC24A5 SP6 SPTSSB STARD5 TET3 TFAP2A TFAP2C TINCR TMEM45A TNFRSF19 TNS4 TP63 TRPM1 TYR UGT3A2 WFDC5 WNT16 WNT3 XCR1 XG ZNF273 Adipose - Visceral (Omentum) Female 40-49 Up ACLY ADAMTS4 ADAMTS9 ADGRL4 ADIPOQ AGPAT2 AIFM2 ALDH1A3 ALOX15 AQP7 ARHGEF15 BTNL9 CD209 CD36 CLDN15 DGAT2 DLC1 DUSP6 ELOVL6 F8 FABP4 FAM89A FASN GAS1 GFPT2 GPAM GPR4 GYG2 HAS1 ITLN1 KDR LGALS12 LPL LRRN4 ME1 MEST MMP19 MSLN MT1A MT1M MUC16 NMB NWD2 PDPN PNPLA2 PPARG PPP1R15B PRG4 PRKAR2B PROCR PRRT4 RARRES1 RNF125 SCD SERPINE3 SLC25A1 SLC7A10 SNAI1 SOCS3 SOX17 SPAAR SPRY1 SRPX THRSP TIMP4 TM4SF18 TSHZ2 UPK3B Colon - Sigmoid Female 40-49 Up ACTG2 ATP2B4 BAG2 BMP3 BMPR1A BTC C3ORF80 CACNA1C CACNA1H CDK8 CHRDL2 CHRM2 COL24A1 CSRP1 DCP1B DIP2C EMILIN1 EML1 FBXL22 FOXF1 FOXP2 FZD7 GDNF GJC1 GLI3 GLP2R GREM2 HAND1 HAND2 HDAC4 HLX HMCN2 HOXA10 HOXA13 HOXB3 HOXB4 HOXD10 HOXD11 HOXD12 HOXD13 KCNMA1 KCNQ4 KIZ KLHL23 KLHL5 LBR LIMS2 LIPI LRCH2 LRIG1 LRRC3 MAB21L2 MASP1 MDM1 MID1 MRGPRF MYH11 MYLK NKX2-3 NKX3-2 NRP2 NT5DC3 NTSR1 NXN PBX3 PDE3B PDZRN4 PGM5 PHOX2B PLA2G2C PLA2G4A PLEKHO1 PNCK PTBP2 PTCHD1 PTGFRN PTGS1 RAB23 RAP1A RNF150 ROR2 RPRM RSPO2 SEMA3A SLC4A7 SMTN SPOP STON1 STON1-GTF2A1L SYDE2 TACR2 TBC1D1 TEAD3 TES TMEM35A TMTC2 TNFAIP8L1 TSPAN2 WNT9A ZEB1 Colon - Transverse Female 40-49 Up ANKDD1B ANKS4B ATOH1 B3GNT6 B4GALNT2 BCL2L15 BEST2 BEST4 BTNL3 C15ORF48 CA1 CA7 CALML4 CAPN5 CASP6 CCL15 CDH17 CDX1 CDX2 CEACAM5 CEACAM7 CES3 CHST5 CLRN3 DHRS11 DQX1 EFNA2 ENTPD8 EPCAM EPS8L3 ERN2 ETHE1 FAM83E FCGBP FOXH1 FXYD3 GAL3ST2 GALNT12 GPA33 GPR35 GUCY2C HEPACAM2 HEPH HHLA2 HOXB5 HOXB9 HSD11B2 IHH ISX KRT20 KRT8 LEFTY1 LGALS4 LRRC19 LRRC31 LYPD8 MARVELD3 MISP MOGAT3 MS4A12 MTMR11 MUC12 NOX1 NPY4R NXPE1 NXPE4 OMP OTOP2 PHGR1 PIGR PIGZ PLA2G10 PLS1 PPP1R14D PRR15 PTGDR2 PYY REP15 RNF186 RXFP4 SATB2 SELENBP1 SLC26A2 SLC44A4 SLC9A2 SMIM22 ST6GALNAC1 TMEM236 TMEM54 TPSG1 TRIM15 TRPM4 TSPAN1 TSPAN8 UGT1A10 UGT1A8 UGT2B17 URAD VIL1 ZG16 Small Intestine - Terminal Ileum Female 40-49 Up ADAM28 ADAMDEC1 ADGRG7 AIM2 ALPI ANXA13 APOBEC1 ATOH1 ATP2A3 BAIAP2L2 BANK1 BLK BMF C17ORF78 CCL25 CCR6 CCR9 CD19 CD1C CD1D CEACAM18 CHST5 CLCA1 CLDN15 CLDN2 CNR2 CTLA4 CXCR5 DEFA5 DEFA6 DERL3 DMBT1 DPEP1 EPHB2 ESPNL FABP2 FAM177B FCMR FCRL1 FCRL2 FCRL3 FCRL4 GPR152 GPR171 GPR82 GPX2 GUCY2C HKDC1 HLA-DOB HNF4G IL17REL IL2 IL24 IL2RA IL7R IRF8 ITLN2 KCNJ13 KLHL6 LGALS2 MADCAM1 MALRD1 MRGPRX4 MUC17 MUC2 MUC3A MYO7B MYRFL NEUROG3 NLRC3 NLRP6 NOS2 OLFM4 OR13A1 P2RX5 PARP15 PLCB3 PRAP1 REG4 RETNLB SCML4 SI SIGLEC6 SLC25A53 SLC28A2 SPINK4 TM4SF20 TM6SF2 TMEM253 TNFRSF13C TP53INP1 TRPM5 UGT1A5 VIL1 VPREB3 XPNPEP2 ZC3H12D ZNF107 ZNF80 ZNF831 Artery - Tibial Female 40-49 Up ACTA2 ACTN4 ADARB1 ADGRL3 ADIRF ALDH1B1 AMIGO2 ARHGEF17 ATL3 C11ORF96 C12ORF75 C1QTNF7 CDH6 CHSY3 CLIC4 CNTN4 COL14A1 COL18A1 COMP CPED1 CRLF1 CRTC3 CSPG4 CSRP2 DACT3 DSTN EFHD1 ENDOD1 FHL5 FOXC1 FOXC2 HEY2 HTR1B ID2 IGFBP7 ITGA5 ITPR1 JAG1 JAK2 KCNA5 KCNAB1 KCTD10 KLHL26 LMOD1 LPP MAP7D3 MBNL1 MCAM MOB2 MSRB3 MUSTN1 MYBL1 NKD1 NOTCH3 NTF3 NTRK3 P2RX1 PDK3 PLEKHG3 PLS3 PMEPA1 PPP1R14A PRELP PRKG1 RASL12 RASSF3 RCAN2 RHOB RNF180 ROCK1 ROR1 RSU1 SDK1 SH3BGRL SH3RF3 SHOX2 SMAD7 SMIM10 SORBS2 SPOPL SUSD5 SYTL2 TAGLN TASP1 TBX18 TBXA2R TGM2 TLN1 TMEM181 TMEM47 TNC TNS1 TOB2 TRABD2B TSC22D1 UBA2 USP35 WDR1 WTIP ZFHX3 Nerve - Tibial Female 40-49 Up AATK ABCA10 ABCA8 AFAP1L2 ANGPTL7 APOD ARHGAP19 ARHGAP39 ARHGEF10 BEST1 BIRC7 BMP8B CASKIN2 CDH19 CDH7 CDO1 CLCN2 CLDN19 CLDN20 CNTF COL28A1 DCLK3 DHH DRP2 EBF2 EGFL8 EGR2 EHBP1 EMILIN3 ENTPD2 EPB41L2 EXTL1 FGFBP2 FIGN FMNL3 FOXD1 FOXD2 FOXD3 GAS2L3 GJC3 GLI1 HSPA12A IL17B IL9 INF2 ITGA6 ITGB8 KANK4 KCNK12 KIF19 LCTL LGI2 LGI4 MAPK8IP1 MATN3 MIA MICALL2 MPZ NCMAP NEK1 NGFR OR2AT4 OR6B2 OR6B3 OTUD7B PAPLN PLEKHA4 PLEKHG7 PLLP PMP22 PRICKLE1 PRIMA1 PRRG3 PRX PTPDC1 PTPRU RTKN SBSPON SCN7A SECISBP2L SEMA3B SEMA4C SEMA5A SFRP5 SH3TC2 SHC4 SLC25A48 SLC2A1 SMCO3 SORCS1 SPTBN5 ST6GALNAC2 THSD7A TLDC2 TMEM215 TMPRSS5 USP53 VIT WNT6 ZDHHC8 Adrenal Gland Female 40-49 Up AADAC ABCB1 ABCC3 ADGRV1 AKAP7 AKR1B1 ALAD ALAS1 AMHR2 AOX1 APOE AS3MT ASB4 C2CD2 C4B CELA1 CLRN1 CREBL2 CTNNAL1 CTSA CYB561A3 CYB5B CYP11A1 CYP11B1 CYP11B2 CYP17A1 CYP21A2 DDB1 DEXI DHCR24 DLK1 DUSP16 EPHX1 FDX1 FDXR GALM GIPC2 GNPTG GNS GSTA1 GSTA3 GSTA4 GSTA5 HDHD3 HSD3B2 IDH1 KCNJ5 KCNK3 KCNN2 KCNQ1 KCTD14 KLHL4 LONP1 MAP3K15 MAP3K5 MC2R MCF2 MCOLN3 MGARP MRAP MRPL33 NR0B1 NR5A1 PAPSS2 PCCB PEBP1 PEG10 PEX3 PLBD2 PPIF PRLR RARRES2 RDX RGN RMDN2 RNF128 SEMA6A SERPINA5 SLC16A9 SLC37A2 SLC40A1 SLC47A1 SLC8B1 SNTB1 SOAT1 SREBF1 STAR SULT2A1 TBC1D4 TBC1D8B TBX3 TKFC TM7SF2 TMEM138 TMEM150C TSPAN12 WHRN ZNF275 ZNF280A ZSWIM5 Brain - Cerebellar Hemisphere Male 30-39 Up ADAM22 AKAIN1 ALS2 ATP6V1G2 BARHL2 BEND6 CA10 CACNG2 CADPS2 CALN1 CAMK4 CAMKK2 CBLN1 CBLN3 CDH18 CDH22 CDH7 CDYL2 CER1 CHD7 CHN2 CLVS2 CNPY1 CNTN6 CPLX4 CRTAM DAB1 DIRAS2 DISP2 DNM3 ETV1 FSTL5 GABRA6 GABRD GALNT13 GPR158 GPR83 GRIK2 GRM1 KCNA1 KCNC1 KCND2 KCNJ3 KCNK10 KCNK9 KCTD2 KCTD8 MEGF11 MKRN2OS NEUROD1 NPTX1 NREP NRXN3 OPCML OR1F1 PAK5 PAX6 PCDHA5 PCDHA8 PCDHGC4 PCLO PKIB POLB PPM1H PSD3 PTPRR RAB37 RAB3IP RELN RIMS1 RIT2 RMND5A RUNX1T1 SCN2A SH3GL2 SHF SNAP25 SPOCK1 SRGAP2 SRGAP2B SSTR2 ST8SIA5 STXBP5L SYT2 SYT4 SYT9 TBC1D3H TIAM1 TMEM163 TMEM266 UNC13C VSX1 VWC2 ZBTB18 ZIC1 ZIC2 ZIC3 ZIC4 ZNF521 ZP2 Brain - Hypothalamus Male 30-39 Up ACHE ADCYAP1 ALK ANKRD34C ATP6V1A AVP B4GAT1 BHLHA9 BSX CALB2 CALCR CBLN2 CBLN4 CENPVL2 CENPVL3 CHRNA6 CLEC19A CNTNAP5 CRH CRHBP DIRAS3 DLX1 ELAVL2 FOXB2 GABRA3 GABRG3 GABRQ GAP43 GBX2 GLRA1 GLRA2 GNG2 GPR179 GPR26 GRM7 HAP1 HCRTR2 HMGCLL1 INPP5F INSM2 IRS4 KCNC2 KCNH5 KIF21A LHX5 LRRC55 MAGEL2 MC4R NAP1L5 NDST4 NGB NHLH2 NMS NPSR1 NTNG1 NTS NXPH1 OPRK1 OXT PAK3 PCDH11Y PCSK1 PEG10 PEG3 PGM2L1 PMCH PNMA2 QRFPR R3HDML RAB3B RAB3C SCG2 SCOC SEZ6L SLC10A4 SLC17A6 SLC2A13 SLC38A8 SLC7A3 SMIM10L2B SMIM17 SMIM18 SNX10 SST STMN2 STXBP6 SYNGR3 TACR3 TMEM114 TMEM17 TMEM196 TMEM255A TMEM35A TRPC5 UNC5D VAT1L VSTM5 VWC2L ZCCHC12 ZDHHC22 Artery - Coronary Male 30-39 Up AEBP1 ANTXR1 ARL4AP5 ART4 ASPN ATF3 BGN C11ORF96 C1QTNF1 C1QTNF2 CCDC3 CCL2 CFH CHST3 CHSY1 CMKLR1 COL15A1 COL18A1 COL4A1 COL4A4 CPED1 CPXM2 CRIP1 DACT1 DUXA ECM2 EDNRA EFEMP1 EMILIN1 EOGT FBLIM1 FMOD FOXC2 FOXL1 FOXS1 FRY GEM GLIS2 GPR20 HAPLN1 HAPLN3 HEYL ID4 IGFBP7 IL33 INHBA ITGB3 IZUMO1R JAG1 KCNA5 KCNK17 KCNT2 LHFPL1 LRRC17 LRRC32 LTBP1 LTBP4 MAP3K7CL MEDAG MFAP4 MFGE8 MINDY4 MKX MSC MTHFD1L MYH10 MYO1D MYOCD NTF3 NTRK3 OGN PAWR PCDHB12 PCDHB7 PCDHB9 PCOLCE2 PDGFA PKIG PLA2G5 PLAC9 PRDM16 PRKG1 PTGIR PTGIS RASL11A RNF180 S1PR3 SLC4A7 SMIM10 SPRY4 ST6GAL2 SULF1 TBX18 TGM2 THBS2 TIMP1 TM4SF1 TRABD2B VCAN WFDC1 Brain - Cerebellum Male 30-39 Up ABCG4 ACAP3 ADAM11 ALS2 ARHGEF33 ASIC3 BLACAT1 BRICD5 BSPH1 CA8 CACNA1A CACNA1G CAMKK2 CARMIL3 CBLN1 CCDC175 CKMT1B CLK4 CNPY1 COL13A1 COL27A1 CPLX4 DISP2 ERVV-1 FAT2 FGF17 FGF3 GABRD GALNT9 GNG13 GRID2 GRID2IP GRIK2 GRIN2C GRM1 GRM4 KCNAB3 KCNC1 KCNK9 KCNT1 LHX1 MEGF11 MMP24 MTCL1 OR1F1 OTX2 PAX6 PBOV1 PCLO PDZD7 PKD1 PLEKHD1 PPFIA4 PPIP5K1 PPP1R17 PRSS51 PTPRR PVALB RAB37 RGS11 RNF112 SBK1 SCN2A SHF SKOR1 SLC1A6 SLC22A31 SLC35F4 SLC6A7 SOGA1 SRGAP2 SRRM3 SRRM4 ST8SIA5 STRC STXBP5L TENM1 TFAP2E TMC2 TMEM120B TMEM132E TMEM145 TMEM178A TMEM266 TRANK1 TRIM3 TRIM67 TRIM9 TRPM3 UNC80 USP17L8 WSCD2 XKR7 ZFYVE28 ZIC3 ZIC4 ZIC5 ZNF337 ZNF382 ZP2 Brain - Cortex Male 30-39 Up ADCY1 ADGRA1 ADGRB2 AGBL4 ANKRD24 ATCAY ATRNL1 BHLHA9 BRINP2 C11ORF87 C2CD4C CABP1 CACNG3 CAMK1G CAMK2A CAMK2N1 CBLN2 CCK CHD5 CHRNB2 CNTNAP5 COL26A1 CREG2 CUX2 DAGLA DLGAP2 DPF1 ENC1 FAM163B FBXO41 FREM3 FRMPD4 GABBR2 GNG3 GPR26 GRIN2A GRIN2B HAPLN4 HECW1 HS6ST3 HTR1A HTR3B ITPKA KCNB2 KCNH1 KCNH3 KCNH5 KCNS1 KCNS2 KCNV1 KCTD16 KIAA1549L KIF3C LCN15 LINGO1 LMO4 LRFN2 LRFN5 LRRC4 LRRTM4 MAP1A MAST3 MCHR1 MCHR2 MGAT5B MPPED1 NCALD NEFL NELL1 NLK NRGN OLFM1 OPRD1 OR14I1 PACSIN1 PDXP PHF24 PI4KA PRKAR1B PTPRT R3HDM1 RAB3A RAB6B RASGRF2 RGS4 RIMKLA RIMS3 RIMS4 RPH3A RTP1 SHC3 SLC17A7 SLC6A17 SPRN STX1A SVOP SYN1 SYT13 TESPA1 TMEM132D Pituitary Male 30-39 Up ARFGAP1 ARHGAP36 ASIC4 BAIAP3 C14ORF39 C17ORF100 C21ORF58 C2CD4A C2ORF15 CACNA1D CBARP CDKN2A CEP126 CERK CFAP47 CFC1 CHD5 CHGB CHST8 CLDN9 CNGA3 COL11A2 COL22A1 COL2A1 COL9A2 CRHR2 CSHL1 DLK1 DPH1 FAM163A FAM86B1 FOXO6 GALR1 GCK GH1 GHRHR GHSR GNAS GNB3 GPHA2 GPR61 HES6 HTATSF1 IGSF1 INSM1 IRS4 KCNH8 KSR2 LHX3 MAGEL2 MYO15A NAALAD2 NEUROD4 NLRP1 NNAT NTN5 NXF2B OR10G3 OR13C2 OTOS PCDHB1 PCSK1N PHF21B PLD3 POMC POU1F1 PRL PRLHR PROP1 REC8 RIIAD1 RIMBP2 RNF224 RPEL1 SCG5 SIX6 SSTR5 TBX19 TCP11X1 TCP11X2 TMEM179 TMEM244 TPH2 TRHR TRPC3 TSHB TUB UBTFL1 UGT2A1 USP17L11 VWA3A VWA5B1 VWA7 VWDE ZDBF2 ZFR2 ZNF10 ZNF667 ZP1 ZSCAN1 Brain - Hippocampus Female 50-59 Up AK5 APC ASPHD1 B3GAT1 B3GAT2 BCAN BHLHE22 C1QL2 CABP7 CACNG3 CACNG8 CAMK2A CCDC85B CNIH2 CNIH3 CNTN5 COPS9 CPLX2 CPNE6 CTXN1 DEAF1 DGKZ DLG2 DLGAP3 DOK6 ELFN2 EPHA5 FEZF2 FGF1 FGF13 FIBCD1 FKBP1B FOXD4L6 FXYD7 GRIA1 GRIA3 HIPK2 HRK HSD11B1L HTR1A IDS JPH3 KCNG2 KCNH3 KCNK4 KCNMB2 KCNN1 LY6H MAP3K10 MAS1 MMP17 MPPED1 MTURN NANOS3 NCS1 NELL2 NEUROD6 NEUROG3 NKX6-2 NOS1AP NPTXR NSMF OLIG1 OLIG2 OPALIN OR4F29 PAIP2B PDE6B PEX5L PHACTR3 PIK3R2 PLPP4 PLPPR3 PLPPR4 PLPPR5 PPM1E PPP1R9B PRKCG PRR18 PSD PSRC1 QDPR RAB11FIP4 RAPGEF4 RASL10A RTP5 SCN3B SEMA6B SEZ6L SHANK1 SHC3 SHTN1 SLC17A7 SLCO1A2 SNPH ST6GALNAC5 STUM TMEM160 TNR TPPP Brain - Anterior Cingulate Cortex (BA24) Female 50-59 Up ADGRA1 AK5 ASIC2 C1ORF216 C1QL3 C2CD4C CACNG3 CALM3 CAMK2A CAMK2N1 CCK CHN1 CLEC2L CREG2 DEAF1 DLX1 DOK6 DPF1 DPP10 DRD5 ELFN2 ENC1 ERC2 FAM163B FAM81A FEZF2 GABRA3 GAD1 GALNT8 GAP43 GDA GDAP1L1 GNG3 GRIN3A HS3ST4 HSD11B1L IDS KCNAB2 KCNC2 KCNN1 KCTD16 KIF3C LIMK1 LINGO1 LMO4 MAGED4 MAP1A MAP2 MAPK8IP2 MEIS3 MLLT11 MPPED1 NANOS3 NAPB NPTXR NRG3 NRSN1 NXPH2 OLFM1 OR4S2 OR5H15 OR8K5 OSTN PACSIN1 PDXP PGM2L1 PHF24 PTER RAB6B RAPGEF4 RGR RGS4 SCN3B SERPINI1 SHANK1 SHC3 SLC17A7 SLC25A22 SLC35F1 SLC39A12 SLIT1 SMIM10L2B SNCA SNCB STUM STX1A SULT4A1 SYN1 SYN2 SYP SYT1 SYT17 TAGLN3 TFPT TMEM132D TTC9B VAMP2 WSB2 YWHAH ZDHHC22 Brain - Amygdala Female 50-59 Up ACBD7 ADCY8 AIFM3 ALDH7A1 ALDOC AMZ1 APC AQP4 ATP1B2 B3GAT1 BCAN C1QL1 C1QL2 CAMK2N1 CDH20 CDH4 CLDN10 CPE CPNE6 CRB2 CSPG5 CST3 CTNNA2 CTNND2 DDAH1 DEAF1 DLL3 DOK6 DSCAM ELFN2 ENHO ETNPPL FAM107A FAM171B FAM181B FBXO2 GABRG1 GLUD1 GPM6A GPM6B GPR37L1 GPR75 GSX2 HEPACAM HIPK2 HMX1 HSD11B1L KCNN1 KCNN3 KIF5C LHFPL3 LHX2 LUZP2 MAPK8IP2 MLC1 MT3 MYRIP NANOS3 NCS1 NKAIN3 NKAIN4 NLGN3 NPAS3 NR2E1 NSMF NTRK2 NTSR2 OLIG1 OLIG2 OPALIN PALM PCDH15 PCDHGC3 PHACTR3 PTPRZ1 RAPGEF4 RASL10A RIMS2 SCD5 SFXN5 SLC18B1 SLC1A2 SLC1A3 SLC25A18 SLC38A8 SMOX SOX2 STON2 STOX1 STUM TAAR6 TFAP2D TFPT TNR TRIL TSPOAP1 TTC9B TTYH1 UNC13C WNT7A Brain - Spinal Cord (Cervical C-1) Female 50-59 Up ABCA2 AGPAT4 ANLN APLP1 BACE1 BCAS1 CA14 CARNS1 CDK18 CHADL CLDND1 CMTM5 CNDP1 CNP CNTN2 CNTNAP4 CT47A12 CTNNA3 DBNDD2 DPYSL5 DRGX DTNB ENPP6 ERMN FA2H FAM124A FEZ1 FGFR2 FMNL2 FNTB GAL3ST1 GFAP GJB1 GJC2 GPR151 GPR37 GPR62 HAPLN2 HMSD HOXB8 HOXD1 KCNJ10 KLK6 LANCL1 LHPP LLGL1 LRRC63 MAG MAP6D1 MAP7 MARCKSL1 MBP MOBP MOG MTMR10 MVB12B MYRF NIPA1 NKAIN2 NKX2-2 NKX6-2 OR2L13 OR5J2 OR9A2 PACS2 PAQR4 PAQR6 PAQR8 PCSK6 PDE6B PEA15 PEX5L PKP4 PLEKHB1 PLP1 PRRG1 RAPGEF5 RASSF2 RBM11 S100B SEC14L5 SEMA4D SIRT2 SLAIN1 SLC44A1 SLC5A11 ST18 STMN4 SYNJ2 TBC1D12 TF TMEM144 TMEM151A TMEM88B TP53INP2 TRAK2 TTYH2 TUBA1A UGT8 ZNF488 Heart - Atrial Appendage Female 50-59 Up ACTC1 ADAMTS7 ADAMTSL2 ALPK2 ANKRD1 ASPG BMP10 C14ORF180 CASQ2 CCDC141 CHCHD10 CHRNE CIB2 CORIN COX5B COX6B1 COX7A1 COX7B CPNE5 CRIP2 CYP2J2 CYSLTR2 DAND5 DHRS7C DKK3 DOK7 FABP3 FGF12 FGF23 FITM2 GATA4 GRXCR2 HCN4 HHATL HRC HSPB2 HSPB3 HTRA3 IGSF5 ITGB1BP2 KCNIP2 KRBA1 LAPTM4B METTL7B MT1HL1 MYBPC3 MYBPHL MYH6 MYL4 MYL7 MYLK3 MYOZ2 MYZAP NDUFA1 NDUFA11 NDUFA4 NDUFAB1 NEBL NES NKX2-5 NKX2-6 NMRK2 NPPA NPPB NRTN OR10P1 OTOGL PAM PCOLCE2 PLA2G5 POPDC2 PPARGC1A PRKAG2 PRR32 PXDNL RABGAP1L RBM20 RBPMS2 RD3L RILPL1 RYR2 S100A1 SBK2 SBK3 SCN5A SHD SLC25A4 SLC4A3 SSTR5 TBX20 TBX5 TECRL TMEM182 TNNT2 TRIM55 TSPAN18 UQCRB VASH1 WNK2 XIRP1 Liver Female 50-59 Up A1BG A1CF ABCB11 ABCB4 ABCC2 ABCG8 ACMSD ACOT12 ALDH8A1 AMBP ANGPTL3 APCS APOA2 APOA5 APOB APOC2 APOC4 ASGR1 ASGR2 ASL ATF5 BAAT C4BPB C5 C8A C8B C8G CA5A CFHR3 CP CPN2 CPS1 CREB3L3 CRP CYP2D6 CYP8B1 DHODH ENPP7 EPO F11 F12 F2 F7 F9 FGA FGB FGG GCGR GCKR GLTPD2 HABP2 HAO1 HGD HP HPD HPX HSD11B1 INHBC INHBE INS-IGF2 ITIH1 ITIH3 ITIH4 KMO LBP LEAP2 MASP2 MAT1A MBL2 NAT2 NR1I3 ORM1 PAH PIPOX PLG PLGLB2 PROC PZP SAA4 SDS SERPINA10 SERPINA6 SERPINC1 SERPINF2 SLC13A5 SLC17A2 SLC22A1 SLC25A47 SLC27A2 SLCO1B1 SMLR1 TDO2 TFR2 TM4SF4 TM4SF5 UGT1A3 UGT1A4 UGT2B4 VTN XYLB Nerve - Tibial Female 50-59 Up AATK ABCA10 ABCA8 AFAP1L2 ANGPTL7 APOD ARHGAP19 ARHGAP39 ARHGEF10 BIRC7 BMP8B CASKIN2 CDH19 CLCN2 CLDN19 CLDN20 CNTF COL28A1 DCLK3 DHH DRP2 EBF2 EGFL8 EGR2 EHBP1 EMILIN3 ENTPD2 EPB41L2 EXTL1 FGFBP2 FIGN FMNL3 FOXD1 FOXD2 FOXD3 GAL3ST1 GAS2L3 GFRA3 GJC3 GLI1 HSPA12A IL17B IL1RAPL1 INF2 ITGA6 ITGB4 ITGB8 KANK4 KCNK12 KIF19 KLRG2 LCTL LGI4 MAPK8IP1 MATN3 MIA MICALL2 MPZ NCMAP NEK1 NGFR OR2AT4 OR6B2 OR6B3 OTUD7B PAPLN PLEKHA4 PMP22 PRICKLE1 PRIMA1 PRRG3 PRX PTCH1 PTPDC1 PTPRU RTKN SBSPON SCN7A SECISBP2L SEMA3B SEMA4C SEMA5A SFRP5 SHC4 SHH SLC25A48 SLC2A1 SMCO3 SORCS1 SPTBN5 ST6GALNAC2 THSD7A TLDC2 TMEM215 TMPRSS5 USP53 VIT VWA1 WNT6 ZDHHC8 Brain - Cerebellum Female 50-59 Up ACAP3 ADAM11 AKAIN1 ARHGEF33 BARHL1 BARHL2 BRICD5 BSPH1 CA8 CACNA1A CACNA1G CAMKK2 CARMIL3 CBLN1 CBLN3 CCDC175 CDH15 CDH22 CELSR3 CKMT1B CNPY1 DAO DISP2 EN2 FAM131C FAT2 FGF17 FGF3 GABRD GALNT9 GNG13 GRID2 GRID2IP GRIN2C GRM1 GRM4 IGLON5 KCNAB3 KCNC1 KCNK9 LCN8 LDLRAP1 LHX1 MAMDC4 MAST1 MCF2L MDGA1 MEGF11 MMP24 MTCL1 MYT1 NKX6-3 NPFFR1 NPTX1 NRXN2 OTX2 PAX6 PKD1 PLEKHD1 PPFIA4 PPP1R17 PRR35 PRSS51 PVALB RGS11 RNF112 SBK1 SHF SHISA8 SKOR1 SLC1A6 SLC22A31 SLC35F4 SOGA1 SRGAP2 SRRM3 SRRM4 ST8SIA5 STRC TFAP2E TLE2 TLX3 TMC2 TMEM132E TMEM145 TMEM178A TMEM266 TNFRSF25 TRIM67 TUBA8 UNCX VSX1 WSCD2 XKR7 ZFYVE28 ZIC2 ZIC3 ZIC4 ZIC5 ZP2 Brain - Frontal Cortex (BA9) Male 20-29 Up ADCY1 APC ATRNL1 ATXN7L3 C11ORF87 C1QL3 CABP1 CALM3 CAMK2A CAMK2N1 CBLN2 CBLN4 CCDC85A CCK CDK5R2 CDKL5 CHN1 CNTNAP2 CNTNAP5 COL26A1 CREG2 CUX2 DCLK1 DLGAP1 DOK6 DPP10 ENC1 EPHA5 ERC2 FAM163B FREM3 FRMPD4 GABBR2 GPR26 GRIN2A GRIN3A GRM5 HCN1 HECW1 HS6ST3 HTR2A HTR3B IDS KCNC2 KCNH1 KCNH5 KCNS2 KCNV1 KCTD16 KIAA1549L KIF3C LINGO1 LMO4 MCHR2 MGAT5B MPPED1 MYO5A NCALD NEFL NELL1 NELL2 NLK NPBWR2 NXPH2 OLFM1 OLFM3 OR14I1 OSTN PCDHGC5 PGM2L1 PHF24 PLCB1 PPFIA2 PRKCB PTPRT R3HDM1 RAB6B RASGRF2 RGS4 RGS7BP RIMKLA RIMS3 RPH3A SERPINI1 SGTB SHANK1 SLC17A7 SLC4A10 SLITRK1 STX1A SULT4A1 SYP SYT1 SYT16 TBR1 TMEM132D VSNL1 VSTM2A WSB2 YWHAG Brain - Cerebellar Hemisphere Male 20-29 Up ADAM11 ADAM22 AKAIN1 ALS2 ANK3 ARFGEF3 BTBD3 CA10 CALN1 CAMK4 CBLN1 CBLN3 CCDC177 CDH22 CHD7 CHN2 CLVS2 CNTN6 CPLX4 DHDDS DIRAS2 DISP2 DNM3 EGR4 ELAVL3 EN2 EPB41 ETV1 FAM131B FAT2 FSTL5 GABRA6 GALNT13 GPR137C GPR158 GPR83 GRIK2 GRM1 GRM4 HECTD4 KCNA1 KCNC1 KCND2 KCNJ3 KCNT1 LHX1 MAB21L1 MEGF11 MMP24 MYT1 NEUROD1 NEUROD2 NREP NRXN2 NRXN3 OPCML OR1F1 PAK5 PAX6 PCDHA11 PCDHA13 PCDHA5 PCDHA8 PCDHAC2 PCDHGC4 PCLO PKIB PLEKHD1 PLK5 PPFIA4 PRSS51 PSD3 PTPN4 RAB3IP RELN RIMS1 SCN2A SLC6A5 SLC8A2 SOGA1 SRGAP2 SRGAP2B SRRM3 SSTR2 STXBP5L SYT2 SYT4 SYT9 TENM1 TIAM1 TRIM67 VSX1 XKR7 ZBTB18 ZIC1 ZIC2 ZIC4 ZIC5 ZNF521 ZP2 Brain - Spinal Cord (Cervical C-1) Male 20-29 Up ABCA2 AGPAT4 ANLN APLNR APLP1 BACE1 CA14 CARNS1 CCNE2 CDK18 CHADL CLDND1 CMTM5 CNDP1 CNP CNTN2 CNTNAP4 CTNNA3 DBNDD2 DNAH17 DPY19L1 DPYSL5 DTNB EDIL3 ENPP2 ENPP6 ERMN FA2H FEZ1 FGFR2 FMNL2 FNTB GFAP GJC2 GPM6B GPR151 GPR37 GPR62 HAPLN2 HMSD IQCJ-SCHIP1 KCNJ10 KLK6 LANCL1 LHPP LRRC63 MAG MAP6D1 MARCKSL1 MBP MMD2 MOB3B MOBP MOG MOSPD2 MTMR10 MVB12B NBPF1 NIPA1 NKAIN2 NKX2-2 NKX6-2 OR5J2 PACS2 PAQR4 PAQR8 PCSK6 PEA15 PLEKHB1 PLP1 PMP2 PPEF1 PRLH PRRG1 RAPGEF5 RASSF2 RNF13 ROM1 S100B SEC14L5 SEMA4D SIRT2 SLAIN1 SLC44A1 SLC6A5 SPOCK3 ST18 SYNJ2 TBC1D12 TF TMEM144 TMEM151A TMEM88B TNFRSF21 TRAK2 TTYH2 TUBA1A UGT8 ZCCHC17 ZNF488 Brain - Cerebellum Male 20-29 Up ABCG4 ACAP3 ADAM11 AKAIN1 ALS2 ARHGEF33 BARHL1 BARHL2 BRICD5 BSPH1 CACNA1G CACNG2 CAMKK2 CARMIL3 CBLN1 CBLN3 CDH15 CDH22 CELSR3 CLEC4G CPLX4 CPNE9 DAB2IP DHDDS EGR4 ELAVL3 EN2 FAT2 FGF3 GABRD GALNT9 GNG13 GPR83 GRID2 GRID2IP GRIK2 GRIN2C GRM4 HSFY2 IFNL3 IGLON5 KCNC1 KCNK9 KCNT1 KCTD2 LHX1 MAB21L1 MADD MAMDC4 MEGF11 MMP24 NEUROD1 NEUROD2 NREP NRXN2 OR13A1 PAX6 PKD1 PLCH2 PLEKHD1 PLK5 PPFIA4 PPIP5K1 PPP1R17 PRSS51 PVALB RAB37 SBK1 SCN2A SKOR1 SLC13A4 SLC1A6 SLC22A31 SLC6A7 SLC8A2 SOGA1 SRGAP2 SRRM3 SRRM4 STRC SYT12 TENM1 TFAP2E TLX3 TMEM145 TMEM266 TMEM63C TRIM3 TRIM67 TRIM9 UNCX WSCD2 XKR7 ZFYVE28 ZIC1 ZIC2 ZIC3 ZIC4 ZIC5 ZSCAN10 Brain - Cortex Male 20-29 Up ADCY1 ADGRA1 ADGRB1 ADGRB2 ANKRD24 APC ATCAY BHLHA9 BRINP2 C11ORF87 C2CD4C CABP1 CACNB3 CACNG3 CCK CHD5 CHRM1 CLEC2L CLSTN1 COL26A1 CREG2 DAGLA DBNDD1 DGKZ DPF1 ELFN2 EPOP EXTL1 FAM163B FAM171A2 FBXO41 FREM3 GABBR2 GALNT8 GPR26 GRIN1 GRIN2A HECW1 HS3ST4 HTR3B IQSEC2 ITPKA KCNF1 KCNH3 KCNIP3 KCNJ4 KCNS2 KIAA1549L KIF21B KIF3C LCN15 LINGO1 LRFN2 LYNX1 MAST3 MCHR1 MCHR2 MGAT5B MPPED1 NCALD NELL1 NELL2 NGEF NLK NRGN OLFM1 OPRD1 OPRL1 OR14I1 PACSIN1 PCDHGC5 PHF24 PI4KA PRKAR1B RAB3A RAB6B RASL10A RIMS3 RIMS4 RPH3A RTN4RL1 SEMA5B SEMA6B SLC17A7 SLC30A3 SLC6A17 SLIT1 SLITRK1 SOHLH1 SPRN STK32C STX1A SULT4A1 SVOP SYP TESPA1 TMEM132D TOLLIP UNC5A VSTM2L Pituitary Male 20-29 Up ALK ARC ARFGAP1 ARHGAP36 ASIC4 AVPR1B B3GALT1 BAIAP3 C14ORF39 C17ORF107 C21ORF58 C2CD4A CBARP CCR10 CERK CFC1 CGA CHGB CHST8 CLDN9 COL11A2 COL22A1 COL9A2 CRHR1 CRHR2 DPH1 DRD2 ENPP5 FAM163A FBXO16 FOXO6 GAGE10 GALR1 GCK GH1 GHRHR GHSR GNAS GNB3 GPHA2 GPR173 GPR50 HES6 HTATSF1 IGSF1 IL11 INSM1 IRS4 LHB LHX3 LMX1A MAGED4B MSI1 MYO15A NAALAD2 NEUROD4 NLRP1 NNAT NTN5 OR10G3 OR13C5 OR13C9 OTOS P4HTM PCDHB1 PCSK1N PHF21B PLD3 POMC POU1F1 PRL PTPRN QSOX2 RAB36 RAB3B RAX RBKS REC8 RIIAD1 RIMBP2 RNF224 SAMD11 SCG2 SCG5 SIX3 SIX6 TAC4 TBX19 TGFBR3L TPH2 TRHR TSHB UGT2A1 VWA7 VWDE WIF1 ZNF10 ZNF571 ZNF667 ZSCAN1 Adipose - Visceral (Omentum) Male 40-49 Up AADACL4 ADAMTS4 ADAMTS9 ADGRF5 ADGRL4 ADIPOQ AGPAT2 AIFM2 ALOX15 APOLD1 AQP7 ARHGEF15 AVPR2 BTNL9 CD209 CD300LG CD36 CD93 CDC42EP2 CDH5 CIDEA CLDN15 CLEC10A CPXM1 CYYR1 DCUN1D3 DLC1 DUSP6 EDNRB F13A1 FABP4 FAM110D FAM89A FGF10 FOLR2 FZD4 GAS1 GFPT2 GNAT3 GPD1 GPIHBP1 GPR4 HAS1 ITLN1 KDR LGALS12 LPL LRRN4 LYVE1 MAP3K8 MEST MMP19 MMRN2 MS4A4A MSLN MT1A MT1M MUC16 MYC NMB NOCT NOTCH4 NR1H3 NWD2 NXNL1 OR52N1 OR52N5 PDPN PLTP PLXNA4 PNPLA2 PPARG PPP1R15B PRKAR2B PROKR1 PRRT4 RASIP1 RBP7 RDH5 RNF125 ROBO4 SELP SIGLEC1 SLC7A10 SNAI1 SOCS3 SOX17 SOX18 SPAAR SRPX SRPX2 TIE1 TIMP4 TM4SF18 TMEM132C TMEM88 TSHZ2 UPK3B VWF WNT11 Brain - Hippocampus Male 20-29 Up ADGRB2 ADRA1D AGAP2 APC ATP1A3 ATP6V0E2 B3GAT1 B3GAT2 BHLHE22 BRINP1 BTBD3 CABP7 CACNG8 CALM3 CAMK2A CDH8 CHCHD6 CHST1 CNGB1 CNIH2 COL24A1 CPLX2 CPNE4 CPNE6 CREG2 DGKZ DLG2 DOK6 ELFN2 ENC1 EPHA5 ERC2 FEZF2 FGF13 FOXD4L3 GABRQ GRIA1 GRIK1 GRIN2B GRM7 HRK HS6ST3 HTR1A ICAM5 KCNAB2 KCNG2 KCNG3 KCNJ6 KCNN1 KLHL2 LINGO1 LRRTM1 LY6H LYNX1 MAS1 MMP17 NCS1 NELL2 NETO1 NEUROD6 NEUROG3 NOS1AP NPTXR NRIP3 NSMF NTS OLFM1 PCDH19 PCDH20 PCDH8 PCDHGC5 PGBD5 PGM2L1 PLPPR2 PLPPR4 PLPPR5 PPM1E PPP4R4 PRKCE PRKCG RTP5 SCN3B SEMA5B SEMA6B SEZ6L SHANK1 SHISA6 SLC17A7 SLC24A3 SLC25A22 SLIT1 ST6GALNAC5 ST8SIA2 STUM SUSD4 SYP TRHDE VSTM2L WASF1 ZDHHC22 Brain - Nucleus Accumbens (Basal Ganglia) Male 20-29 Up ACTR3B ADORA2A AKAP5 ANKRD63 ANKRD66 ANO3 ARPP19 ARPP21 BCR CACNA1E CACNG4 CACNG5 CALB1 CAMKV CHRM4 COCH CRYM CYP46A1 DDN DGKB DLGAP3 DLX6 DNAH9 DRD1 DRD3 DYDC2 EFNB3 FBXL16 FRMPD2 GABRA5 GALNTL6 GNAL GNG7 GPC5 GPR101 GPR139 GPR149 GPR27 GPR52 GRM3 GRM5 GSG1L HPCA HTR1D HTR2C HTR6 IL5RA IMPG1 JAKMIP1 KCNH4 KCNIP1 KCNQ3 KHDRBS2 KIAA2012 KLF16 LAMP5 LHFPL3 LINGO3 LRRC10B LZTS1 MC4R MINDY4B NCDN NECAB2 NNAT OTOF PCDHGC5 PCP4 PCP4L1 PDE10A PDE1B PDYN PENK PHACTR1 PLPPR3 POU3F4 PPP1R16B PPP1R1B PRKCB PRR7 PTPN5 RAB40B RESP18 RGS14 RGS8 RIMS4 RPRML SCN4B SH2D5 SLC25A23 SLC32A1 SLC35D3 SOWAHA SOX1 SPEF1 STOML3 SYNDIG1L SYNPR TMEM158 VAX1 Brain - Putamen (Basal Ganglia) Male 20-29 Up ACTR3B ADORA2A AMBN ANKRD34B ANO3 ARPP19 ARPP21 BCR CACNA2D3 CACNG4 CACNG5 CDK5R2 CENPVL2 CHRM4 CPLX1 CTXN1 CYP46A1 DACT2 DGKB DLGAP3 DLX6 DRD1 DRD2 EFR3B ENTPD3 EPHX4 EYA1 FBXL16 GNAL GNG7 GPR139 GPR27 GPR52 GPR6 GPR88 GRM3 GSG1L HAGHL HCN2 HPCA HRH3 HS3ST5 HTR6 ITPKA JAKMIP1 KCNAB1 KCNF1 KCNH4 KCNK10 KCNQ3 KCTD17 KLF16 LHFPL3 LINGO3 LRP3 LRRC10B LRTM2 NCDN NETO1 NGEF NRGN ONECUT2 OTOF PCP4 PCP4L1 PDE10A PDE1B PENK PHACTR1 PLCB1 PPP1R16B PPP1R1B PPP3CA PRKCB PRMT8 PTPN5 RAB40B RASD2 RGS14 RGS7BP RGS8 RGS9 RIPPLY3 ROBO2 RXRG SCN4B SLC25A23 SLC32A1 SLC35D3 SMPD3 SOWAHA SP9 SPEF1 SPOCK3 ST8SIA3 SYNDIG1L TAC1 TESC TMEFF1 TMEM158 Whole Blood Male 70-79 Up ADGRG3 ADIPOR1 AHSP ALAS2 ARRB2 AZU1 BPGM BPI C5AR1 C9ORF78 CARD19 CCL5 CD247 CD300A CD300C CD300E CD300LB CD7 CDKN2D CEACAM8 CR1L CTSG CTSW CXCR4 CYTIP DCAF12 DHX34 ELANE EPB42 FAM210B FBXO7 FCAR FCN1 FKBP8 FMNL1 GATA1 GFI1B GNLY GTPBP1 GYPB GYPC GZMB HBA1 HBA2 HBB HBD HBG1 HBG2 HBM HBQ1 HCAR2 HCAR3 IFI30 IFIT1B KIR2DL3 KIR3DL1 KLF1 LCP2 LSP1 MFSD2B MPO MPP1 MXD1 NFKBID NINJ1 NKG7 NLRP3 NPRL3 OR2W3 OR51B6 OR52B2 OR52E1 OSM PF4 PHOSPHO1 PLAUR PLEK PRSS57 PRTN3 R3HDM4 RBM38 RELT RHD RHOG RNF10 SH2D2A SLA2 SLC25A37 SLC25A39 SLC2A3 SLC4A1 SMIM1 STRADB SYTL3 TNFRSF1B TREM1 TRIM10 TRIM58 TSPO2 UBA52 Cells - Cultured Fibroblasts Male 70-79 Up ABI3BP ADAM9 ADAMTS12 ADAMTS6 ALDH1L2 ANXA2 ANXA5 CALU CCBE1 CCDC80 CD109 CKAP4 CLEC11A COL12A1 COL1A1 COL1A2 COL5A2 COL6A3 COPB2 CTHRC1 CUL4B DCBLD2 DKK1 DSEL EDA2R FAP FBN1 FBN2 FGF5 FKBP10 FKBP14 FN1 FRMD6 GALNT5 GCNT1 GNPNAT1 GPX8 GREM1 HAS2 HIF1A HMGA2 HOXC8 HS3ST3A1 HS3ST3B1 IGF2BP1 IGF2BP2 IGF2BP3 IKBIP ITGBL1 KCNK2 KDELR3 LAMC1 LGALS1 LMAN1 LOX LOXL2 MAN2A1 MME MYOF NABP1 NECTIN3 NID2 NT5E OR1J4 OSTC PAPPA PCDHGA11 PCDHGB5 PCOLCE PLOD1 PLOD2 PSG1 PSG2 PSG4 PTX3 RAI14 RCN1 RCN3 RFX8 RPL22L1 RRAS2 SEC22B SEC24D SERPINE1 SKP2 SPOCD1 SSR3 STEAP1 STEAP1B STT3A TGFBI TNFRSF10D TRAM1 TRAM2 TRNP1 TTPAL TWIST2 VGLL3 WNT5A YIPF5 Brain - Frontal Cortex (BA9) Male 70-79 Up ADGRA1 AGBL4 AK5 ANKRD24 BHLHA9 BRINP2 CABP1 CAMK1G CBLN2 CCK CHN1 CLEC2L CNTNAP2 COL26A1 CREG2 CRYGA CTNNA2 DLGAP1 DPP10 EIF4E1B ELAVL4 EMX1 ENC1 FAM163B FAM81A FOXD4L3 FOXD4L6 FOXG1 FSTL4 FXYD7 GABBR2 GRIA3 HAPLN4 HCN1 HECW1 HTR2A HTR3B KCNB2 KCNC2 KCNH5 KCNS1 KCNS2 KCNV1 KIF5A LCN15 LINGO1 LMO4 LRFN2 LRFN5 MAPK10 MCF2L2 MGAT5B MPPED1 NAGPA NANOS3 NAP1L2 NECAB1 NEFL NEFM NELL1 NELL2 NEUROD6 NPBWR2 NRGN OLFM1 OLFM3 OPRD1 OR14I1 PDE6H PLEKHM2 PNMA3 PNMA6A POU6F2 PRKAR1B PTH2R PTPRT RAB3A RGS4 RHBDL3 RIMS3 RNF208 RORB RPH3A RXFP1 SERPINI1 SLC39A12 SLITRK1 SNCB SOHLH1 STX1A SULT4A1 SYN1 SYT1 TAGLN3 TBR1 TESPA1 TMEM132D VAMP1 VSNL1 ZNF365 Brain - Cerebellar Hemisphere Male 70-79 Up ADAM22 AKAIN1 ALS2 AMER3 ANKRD18B BARHL1 BARHL2 BRICD5 CA10 CACNA1A CAMK4 CBLN1 CBLN3 CCDC175 CDH15 CHD7 CHN2 CKMT1B CNPY1 COL13A1 CRTAM DIRAS2 DISP2 EN2 EPB41 ETV1 FAM131C FGF17 FGF9 FLT3 FSTL5 GABRA6 GABRD GLCE GPR83 GRIK2 GRM4 IGLON5 KCNC1 KCND2 KCNK9 KIF25 LHX1 MAB21L1 MDGA1 MTCL1 MYT1 NBPF20 NEUROD1 NEUROD2 NKX6-3 NPFFR1 NRXN3 OTX2 PAK5 PAX6 PCDHGC4 PKIB PLGLB1 PLK5 PPFIA4 PRR35 RAB26 RBFOX3 RELN RHBDL1 SCN2A SHF SHISA8 SLC22A31 SLC35F4 SLC6A7 SLC8A2 SRRM3 SRRM4 STRC SYT2 SYT4 TFAP2E TIAM1 TLX3 TMC2 TMEM145 TMEM178A TMEM266 TNFRSF25 TUBA8 UBAP1L UNCX VSX1 VWC2 ZBTB18 ZFYVE28 ZIC1 ZIC2 ZIC3 ZIC4 ZIC5 ZNF382 ZNF521 Brain - Hippocampus Male 70-79 Up AMER2 ANKRD66 APC ASTL B3GAT2 C1QL2 C1QTNF9B C2ORF50 C7ORF57 C8ORF34 CABP7 CACNG8 CAPS CAPSL CERCAM CFAP157 CFAP161 CFAP52 CFAP73 CHST6 CNDP1 CNIH2 CNP CNTN2 CRB2 DNAH9 DSCAML1 DYDC2 ENKUR ENO4 EPHA5 FEZF2 FIBCD1 FNDC7 FOXJ1 FRMPD2 GPR37 GPR62 GPRC5B GRIA1 HHIP HIPK2 HRK HTR1A KCNG2 KCNH8 KHDC3L KIAA2012 KIF6 KLHL32 KRTAP25-1 LY6H MAS1 MKRN3 MOG MTURN MYRF NEK5 NEUROD6 NEUROG3 NKX6-2 NPTXR NSMF NTS OLIG1 OLIG2 OMG OPALIN OR12D1 OR12D2 OR4F16 OR4F29 PAIP2B PDE6B PIP4K2A PPM1E PRKCG PRR18 PSRC1 PTRH1 QDPR RAPGEF4 RTP5 SDR42E2 SHTN1 SLC47A2 SLCO1A2 SPAG8 SPOCK3 STOML3 SYTL5 TMEM144 TMEM151A TMEM235 TMEM88B TMTC4 TNR TTLL9 TTYH2 WDR49 Brain - Substantia Nigra Male 70-79 Up ADCYAP1R1 ALDH7A1 AMOT ANKRD40 APOE ARHGEF6 ASB3 BAALC BCAS1 C10ORF105 C18ORF32 C1ORF122 C1ORF54 CA14 CABLES1 CCDC160 CDH20 CLU CNDP1 CST3 DBX2 DTNA ENPP5 F2RL2 FAM107A FAM181B FGF1 FOXB1 GCSH GLUD1 GNA12 GPR143 GPR151 GPR37L1 HEPACAM HIPK2 ITPKB KAT2B KCNE5 KCNN3 KIF6 LHFPL1 LIX1 LYPD1 MBP MED29 METRN MRO MT3 MTURN NDRG2 NKAIN4 NKX6-2 NPAS3 NTSR2 OXTR PAIP2B PAQR6 PBXIP1 PEX10 PIP4K2A PIRT PITPNC1 PLEKHB1 PPIAL4G PRLHR PRR18 RIDA RND2 ROM1 RPE65 S100B SCD5 SCRG1 SEC14L2 SHISA6 SHTN1 SLC15A5 SLC25A18 SLC39A12 SLC5A11 SLC6A11 SLC6A3 SLCO1A2 SMOX SOX2 SPACA5 SPX SRI STK32A TCFL5 TECTB TLCD1 TMEM88B TRIL TRPM3 TSC22D4 TTYH1 TTYH2 TUBB2B Brain - Anterior Cingulate Cortex (BA24) Male 70-79 Up ACBD7 ADGRB1 AMZ1 ARHGDIG ASIC2 BCAN BRINP2 BRSK1 BTBD2 C1QL2 C2CD4C C2ORF80 CA11 CACNG5 CAMK2A CAMK2N1 CASKIN1 CCK CNTN5 COL20A1 CRYGA CSPG5 CTNND2 DBX2 DEAF1 DLX1 DOK6 DPF1 DSCAM ELFN2 FAM107A FAM163B FBXO41 FOXG1 FXYD7 GABRA3 GRIN3A HEPACAM HPCAL4 HSD11B1L IDS JPH3 KCNIP1 KCNN1 KIF1A KIF5A KIF5C KLRC2 LHFPL3 LHX2 LIMK1 LY6H MAP2 MAP3K10 MAPK8IP2 MCF2L2 MEIS3 MPPED1 MT3 MYRIP NANOS3 NCAN NCS1 NECAB2 NKAIN3 NKAIN4 NPTXR NR2E1 NSMF OLFM1 OLFM2 OR7C2 PACSIN1 PALM PLPPR5 PTER PTPRZ1 RAPGEF4 RASL10A RNF182 RUNDC3A SEZ6L SFXN5 SHANK1 SHC3 SLC25A18 SLC39A12 SLC6A1 SMIM10L2A SNCB SNPH STOX1 STUM SYN1 SYT17 SYTL2 TFPT TNR TSPOAP1 TTC9B Brain - Amygdala Male 70-79 Up ADAP1 ADARB2 ALDH7A1 AMZ1 BCAN C1QL1 C1QL2 CAMK2N1 CDH4 CERS1 COPS9 COX6A1 CSPG5 DCSTAMP DEAF1 DLL3 DSCAM ELFN2 ENHO ETNPPL FAM107A FAM181B FBXO2 FXYD7 HIPK2 HMX1 HSD11B1L KCNG4 KCNIP1 KCNK4 KCNN1 KLRC2 KLRC3 LHFPL3 LHX2 LY6H MAPK8IP2 MEIS3 MT3 MYRIP NANOS3 NCS1 NKAIN4 NPAS3 OCM OLIG1 OLIG2 OPALIN PALM PCDH15 PHACTR3 PLPPR1 PRR18 PTPRZ1 RAPGEF4 RASL10A ROM1 RTP5 SAPCD2 SCD5 SHTN1 SLC25A18 SLC38A8 SLCO1A2 SOX8 STMN4 STON2 SYTL5 TFAP2D TFPT TMEM160 TNR TSC22D4 TSPOAP1 TTC9B ZBTB8B ZNF713 Brain - Caudate (Basal Ganglia) Male 70-79 Up ACBD7 ALDH7A1 ANKRD34B ANO3 AQP4 ARPP19 ARPP21 ATP1B2 C1ORF87 C4ORF50 CABLES1 CACNG4 CDH20 CHAT CNMD CORT CPE CTXN1 CYP46A1 DACT2 DLX6 DRD1 ENTPD3 ETNPPL GABRA2 GABRB1 GABRG1 GBX2 GNG7 GPC5 GPR143 GPR6 GPR75 GPR88 GRM3 HEPACAM HPCA HRH3 HS3ST5 HTR6 IL17D IQCA1 JAKMIP1 KCNH4 KCNN3 KCTD17 KIRREL3 LGI1 LIX1 LRRC10B LRTM2 MAPK4 MC4R MEGF10 MLC1 NCDN NDP NGEF NHLH1 NKAIN3 NR2E1 NTRK2 NTSR2 ONECUT2 OTOF PCDHGB1 PCP4 PCP4L1 PDE1B PON2 POU3F4 PPP1R1B PPP3CA PSD2 PTPN5 RANBP3L RASD2 RESP18 RGS14 RGS20 RGS9 RIC8B RLBP1 SCN4B SIX3 SLC1A2 SLC24A2 SLC25A23 SLC9A7 SLIT1 SP9 SPEF1 STON2 STRIP2 SYNDIG1L TAC1 TNIK TRIM77 VAX1 WDR49 Brain - Nucleus Accumbens (Basal Ganglia) Male 70-79 Up AKAP5 ANKRD34B ARPP21 C1QTNF4 C4ORF50 C6ORF141 CACNA1E CACNG4 CAMK1G CAMKV CELF5 CNMD COCH CPNE5 CRYGA CRYM CTXN1 CYP46A1 DACT2 DLL3 DLX6 DRD1 DTNBP1 GABRA5 GAD2 GNAL GNG7 GPR6 HRH3 HSPBP1 HTR1D HTR2C HTR6 ICAM5 IDNK IMPG1 JAKMIP1 KCNA4 KCNH4 KCNIP1 KCNK4 KCTD4 KIRREL3 KISS1R KLF16 KLHL35 LAMP5 LMTK3 LRRC7 LRRTM1 LYPD1 MMP17 MT3 NAT16 NCDN NECAB2 NKAIN4 NTSR2 OPRK1 OTOF PCDH11X PCP4 PDE1B PDYN PENK PIANP PLPPR1 PLPPR3 PNMA5 POU3F4 PPP1R1B PRKCG PRMT8 PRR7 PSD PTPN5 RAB40B RAP1GAP RESP18 RGS20 RPRML RTP5 SH2D5 SHISA7 SIX3 SLC32A1 SLC9A7 SNX32 SOWAHA SOX11 SPEF1 SYNDIG1L SYNPR THRA TMEM158 UCN VAX1 WNT1 WNT10B YJEFN3 Brain - Putamen (Basal Ganglia) Male 70-79 Up ADORA2A ALDH7A1 AMBN ANKRD34B ANO3 ARPP19 ARPP21 BCR C1QTNF4 C6ORF141 CACNG4 CHAT CNDP1 CNMD COCH CORT CPLX1 CTXN1 CYP46A1 DACT2 DGKB DLX6 DRD1 DRD2 ENTPD3 ETNPPL EYA1 FBXL16 GBX2 GNG7 GPR143 GPR151 GPR52 GPR6 GPR88 GRM3 HCN2 HEPACAM HPCA HRH3 HS3ST5 HTR1D HTR6 JAKMIP1 KCNF1 KCNH4 KCTD17 KIRREL3 LGI1 LINGO3 LIX1 LRRC10B LRRC3B LRRTM1 LRTM2 MAPK4 MC4R METRN MT3 NCDN NGEF NRGN OLIG2 ONECUT2 OPALIN OR7C2 OTOF PCP4 PDE10A PDE1B PENK PPP1R1B PPP3CA PRR7 PTPN5 RASD2 RESP18 RGS14 RGS20 RGS9 RLBP1 RPRML SCN4B SIX3 SLC18A3 SLC25A23 SLC39A12 SOWAHA SP9 SPEF1 ST8SIA3 SYNDIG1L SYT5 TAC1 TMEM158 TPBGL TRIM77 TUBB2B VAX1 YJEFN3 Nerve - Tibial Male 70-79 Up AATK ABCA10 ABCA8 ADD3 AFAP1L2 AHR ANGPTL7 APOD ARHGAP15 ARHGAP19 ARHGAP39 ARHGEF10 ARHGEF37 BMP8B C12ORF56 C2ORF88 CDH19 CHL1 CLDN19 COL28A1 CTNNAL1 CYB5R2 CYP2U1 DCLK3 DHH DLEU7 EGFL8 EHBP1 ENTPD2 EPB41L2 FIGN FOXD1 FOXD2 FOXD3 FXYD1 GAB1 GAS2L3 GFRA3 GJC3 GLI1 GNRH1 GRIK3 HSPA12A IL1RAPL1 IL34 INF2 INSC ITGA6 ITGB4 ITGB8 KANK4 KCNMB4 LGI4 MIA MICALL2 MMP28 MPZ NCMAP NDST4 NEK1 NGFR NRBP2 PAPLN PLAG1 PLEKHA4 PMP22 PODNL1 PRELID3A PRICKLE1 PRIMA1 PRX PTCH1 PTPDC1 RDH10 RHBDF1 SAMHD1 SBSPON SCN7A SEMA3B SFRP5 SHC4 SHH SLC25A48 SLITRK5 SMCO3 SMIM5 SORCS1 SPTBN5 ST6GALNAC2 STARD13 SYT10 TET1 THSD7A TLDC2 TLE1 TMOD2 TMPRSS5 VWA1 WNT6 XKR4 Muscle - Skeletal Male 70-79 Up ABLIM2 ADSL AK1 AMPD1 ANKRD23 ANKRD9 ART1 ART3 ASB10 ASB16 ASB8 BEST3 BIN1 CACNA1S CACNB1 CACNG1 CACNG6 CAND2 CAP2 CAPN3 CAV3 CHRNA10 CHRNB1 CHRND CHRNG CLCN1 CLTCL1 CMYA5 CORO6 CUTC DDIT4L DNASE1L1 EEF1A2 FAM184B FBP2 FXR1 GAMT GMPR HYAL4 IP6K3 ITIH6 JPH1 JSRP1 KCNA7 KCNJ11 KLHL30 KLHL33 KLHL41 LINGO4 LMOD3 LRRC30 LRRC38 MACROD1 MAMSTR MAPK12 MUSK MYBPC1 MYH8 MYLK2 MYO18B MYOG MYOZ1 MYPN NEB OPTN OSBPL6 PACSIN3 PCNT PDE4DIP PDLIM3 PFKM PGM1 PHKG1 PLAC1 PTGES3L RAPSN RBM24 RNF123 RPL3L RRAD RYR1 SLC8A3 SLN SMTNL2 SMYD1 SRPK3 STAC3 TCEA3 TEAD4 TMOD4 TNNC2 TNNI2 TNNT3 TRIM54 TRIM72 TXLNB UBAC1 USO1 USP13 YBX3 Adipose - Visceral (Omentum) Male 70-79 Up AADACL4 ABLIM3 ADAMTS3 ADAMTS9 ADGRD1 ADGRL4 ALDH1A2 ALDH1A3 ALOX15 ANGPT2 ANGPTL2 ANO2 ANXA8 AREG ARHGEF15 BCHE BDKRB1 BNC1 BTNL9 C21ORF62 C3 C7 CCRL2 CD209 CD36 CDON CLDN15 CLIC2 CPXM1 CRLS1 DAPK1 DCUN1D3 F8 FABP4 FAM110C FAM167B FGF10 FLRT3 FOLR2 GAS1 GFPT2 GNAT3 GNG11 GPR4 HAS1 HBEGF HLX IGF2 IL1R1 ITLN1 KDR KRT18 LEPROTL1 LRRN4 LXN LYVE1 MEDAG MSLN MUC16 MYCT1 NOCT NOTCH4 NRP1 OLFML1 PCSK5 PDGFB PDPN PLIN2 PLTP PRG4 PROCR PTPRQ RARRES1 RBP7 ROBO3 ROBO4 RSPO1 SDE2 SERPINE3 SGK1 SLC28A3 SLC39A8 SOX17 SPAAR SPRY1 ST6GALNAC3 TIE1 TM4SF1 TM4SF18 TNFRSF4 TSHZ2 UPK1B UPK3B USP17L13 VIPR2 VWF WFDC8 WNT11 WT1 ZNF366 Skin - Not Sun Exposed (Suprapubic) Male 70-79 Up ACSM6 ADGRF2 ANXA8L1 ARHGEF19 ASCL2 ATP6V1B1 AWAT2 BICD2 CA6 CAPNS2 CARD18 CCL27 CLDN1 COL17A1 COL7A1 CST6 DAPL1 DEGS1 DLX3 DLX4 DNASE1L2 DSC3 EDN2 EFNA3 EFNA4 ELOVL3 EXPH5 FAM83B FOXN1 FZD10 GAL3ST4 GATA3 GPNMB HELT HES1 HOXC13 HS3ST6 HSD3B1 IGFL2 IGFL3 IL20RA IRF6 IRX2 IRX3 IRX4 IRX5 KCNK7 KLC3 KLF4 KLK14 KREMEN2 KRT1 KRT10 KRT14 KRT17 KRT27 KRT31 KRT35 KRT5 KRT71 KRT75 KRT77 KRT79 KRT85 KRTAP11-1 KRTDAP LAMB4 LAMTOR4 LGALS7B LIPK LY6G6D LYPD6B NECTIN4 NR1D1 NXPH4 OR5P3 OTOP1 PERP PM20D1 PNLIPRP3 PNPLA5 POU2F3 RAB7B RASSF10 RNF39 SLC39A2 SP6 SPINT3 SPTSSB SRD5A1 TCHH TCHHL1 TFAP2A TFAP2C TMEM254 TMEM45A TNFRSF19 TNS4 TP63 WNT3 Pituitary Male 70-79 Up ABCC8 ADGRD2 AHI1 ARFGAP1 ARHGAP36 ASCL1 ASIC4 BAIAP3 BPIFB4 C14ORF39 C17ORF107 C21ORF58 C2CD4A C2ORF15 CCR10 CDKN2A CDRT4 CFAP47 CFC1 CHGB CHST8 CITED1 CNGA3 COL11A2 COL22A1 COL9A2 COQ8B CRHR2 CSH1 CSHL1 DGKK DLK1 DMRTC1B DRD2 EME2 FAM163A FBXO16 FFAR4 FICD FOXO6 GAL GCK GH1 GHRHR GHSR GJD2 GNAS GNB3 GPR50 HFM1 HTATSF1 IGSF1 INSM1 KCNH6 KRBA1 KSR2 LHX3 LMX1A MYO15A NAT16 NEUROD4 NLRP1 NNAT NPHP4 NPTX2 OR13C2 OR13C5 OR13C9 OTOS PCDHB1 PCSK1N PHF21B POMC POU1F1 PRL PROP1 REC8 RIIAD1 RIMBP2 RNF224 RPH3AL RTBDN SCG5 SIX6 SPRED3 SSTR5 TBX19 TCP11X2 TMEM244 TMEM61 TMEM63C TRHR TRPC3 VWA7 VWDE ZFR2 ZNF10 ZNF667 ZP1 ZSCAN1 Brain - Cortex Male 70-79 Up ADGRA1 ADGRB1 ADGRB2 AGBL4 ALDOC ANKRD24 APC2 ATCAY BHLHA9 BRINP2 BRSK1 C2CD4C CABP1 CAMK1G CASKIN1 CBLN2 CDIP1 CEND1 CHD5 CIT CLEC2L COL26A1 CTNNA2 DAGLA DNM1 DPF1 EIF4E1B ELFN2 FAIM2 FAM107A FAM163B FAM81A FEZF2 FOXG1 FXYD7 GABBR2 GALNT8 GRIN1 HAPLN4 HECW1 HEPACAM HS3ST4 HTR3B KCNAB2 KCNB2 KCNH3 KCNJ4 KCNS1 KIF1A KIF5A LCN15 LHX2 LIMK1 LINGO1 LRFN2 LRFN5 LYNX1 MAP1A MAPK10 MCF2L2 MGAT5B MPPED1 NAGPA NCALD NEFL NPBWR2 OPRD1 OR2M4 PACSIN1 PDXP PHF24 PI4KA PKD2L1 PLEKHM2 PNMA3 PNMA6A POU6F2 PRKAR1B PTPRT RAB6B RAPGEF4 RHBDL3 RIMS3 RNF208 RORB RPH3A RXFP1 SCG3 SHC3 SLC39A12 SLC6A17 SNCB SNPH SOHLH1 STX1A SYN1 TBR1 TESPA1 UNC5A ZDHHC22 Kidney - Cortex Female 50-59 Up ABCA4 ADGRF1 ADGRF3 ALX1 AMACR AQP2 AQP6 ATP6V0A4 ATP6V0D2 ATP6V1B1 ATP6V1G3 BSND C11ORF54 CALB1 CDH16 CDH6 CLCNKA CLCNKB CLEC18C CLNK CRYAA CUBN CYP24A1 CYS1 DCDC2 DMRT2 DUSP9 EMX1 ENAM ESRRB FOXI1 FRMD7 FXYD2 FXYD4 HNF1B HOXB6 HOXD8 IL17RB INSRR KCNJ1 KCP KIF12 KL LRP2 LY6L LYG1 MCCD1 NAT8 NPHS1 NPHS2 OGDHL OR4F29 PAQR5 PAX2 PDZK1 PDZK1IP1 PKHD1 PODXL PSKH2 PTGER1 PTH1R PTH2R RBP5 RDH8 REN RHBG SLC12A1 SLC12A3 SLC13A1 SLC13A3 SLC14A2 SLC16A4 SLC17A1 SLC17A3 SLC22A11 SLC22A12 SLC22A13 SLC22A2 SLC22A24 SLC22A6 SLC22A8 SLC34A1 SLC47A2 SLC4A9 SLC5A10 SLC5A2 SLC6A12 SLC6A13 SPP1 TINAG TMEM101 TMEM213 TMEM252 TMEM52B TMEM72 TNFSF15 TRPV5 UGT1A9 UGT2B7 UNC5CL Spleen Female 50-59 Up ABI3 BANK1 BTN3A1 BTN3A3 C1QA C1QB C1QC CABP4 CCL24 CCM2L CCR5 CD163L1 CD180 CD19 CD1C CD1D CD22 CD4 CD5L CD72 CD79B CD84 CD8A CERKL CETP CNR2 CR2 CSF1R CXCL13 CXCL6 CXCR5 DNASE1L3 EMID1 EXOC3L1 FCMR FCRL1 FCRL2 FCRL3 FCRL5 FGD2 FHOD1 FLI1 GDPD2 GDPD5 GPR182 GRAP HLA-DOB HMOX1 HYAL1 HYAL2 IL10RA IL24 IRF8 ITGAD KAZALD1 LAX1 LILRA4 LILRB1 LILRB5 LIPA LRTM1 MPEG1 MS4A7 MZB1 NLRC3 NLRC5 NOS3 NOX5 NPY1R NR5A1 NTN4 OR5AK2 OR9G4 P2RX5 P2RY6 PARP15 PATL2 PDE6G PIM2 PPM1N PSTPIP2 RENBP SCN11A SEMA3D SIGLEC12 SLC9A5 SPIC STAB1 STAB2 TAS1R3 TLX1 TMC8 TMEM156 TMEM26 TNFRSF13C TRAPPC3L TTC24 TXNDC5 VCAM1 ZNF831 Brain - Hippocampus Male 50-59 Up ADAP1 ADGRB2 ADRA1D AGAP2 AK5 APC ASPHD1 B3GAT1 B3GAT2 BHLHE22 C1QL2 CABP7 CACNG8 CAMK2A CCDC85B CERCAM CHCHD6 CNIH2 CNIH3 COPS9 CPLX2 CPNE6 CTXN1 DEAF1 DGKZ DLG2 DLGAP3 DOK6 ELFN2 EPHA5 FEZF2 FGF13 FIBCD1 FKBP1B FOXD4L3 FXYD7 GRIA1 HRK HSD11B1L HTR1A ICAM5 IDS JPH3 KCNAB2 KCNG2 KCNH3 KCNK4 KCNMB2 KCNN1 LY6H MAP3K10 MAS1 MATK MMP17 MPPED1 NCS1 NEUROD6 NEUROG3 NPTXR NRIP3 NSMF OLIG1 OLIG2 OPALIN PCDH11Y PDE6B PDZD4 PIK3R2 PLPPR3 PLPPR4 PLPPR5 PPM1E PPP1R9B PRKCG PRR18 PRR7 PSD PSRC1 RAPGEF4 RASL10A RFK RNF208 RTP5 SCN3B SEMA6B SEZ6L SH3GL3 SHANK1 SHTN1 SLC17A7 SLC24A3 SLCO1A2 SMIM10L2A SNPH ST6GALNAC5 STUM TMEM151A TMEM160 TMEM235 VSTM2L Lung Female 40-49 Up A2M ABCA3 ACOXL ACP5 ACVRL1 ADAMTS8 ADGRF5 ADGRL2 AGER AGTR2 ALDH3B1 ANOS1 ATP11A BMP5 CACNA2D2 CALCRL CASS4 CCDC102B CCL18 CCL23 CEACAM6 COL6A5 CSF2 CTSH DOCK4 DRAM1 EMP2 EPAS1 FCN3 FGFR4 FLRT3 FOLR1 GBP4 GGTLC1 GPC3 GPRC5A HECW2 HTR3C HTRA4 ICAM1 IL7R INMT ITGB6 LAMP3 LPCAT1 LRRK2 LTK MARCO MRC1 MS4A15 MSLN NAPSA NCKAP5 NDNF NKD2 NPC2 OLR1 PCDH12 PHEX PIGA RAMP3 RBMS2 RGCC RHOBTB2 RNF145 ROS1 RS1 RTKN2 SCGB3A2 SFTA2 SFTPA1 SFTPA2 SFTPB SFTPC SFTPD SHROOM4 SLC34A2 SLC39A8 SLC6A14 SLC6A4 SLCO2A1 SLCO4C1 SMAD6 SNX30 STARD8 SUSD2 TAL1 TBX2 TBX4 TCF21 TFEC TFPI TMEM100 TMEM125 UNC13B VEGFD VEPH1 VIPR1 WNT2 WNT3A Artery - Aorta Female 40-49 Up ACAN ADAMTSL3 ADRA1B ADRA1D AEBP1 ANO1 ANTXR1 ASPN BGN C1QTNF2 C1QTNF8 CD151 CDH13 CNTN4 COL14A1 COL21A1 COL8A2 CPXM2 CRISPLD1 EFEMP1 ELN EXT1 FBLIM1 FBLN5 FGL2 FILIP1L FMOD FOXC1 FOXC2 FRZB GABRR1 GAS6 GDF7 HAPLN3 HMCN1 IGFBP2 IGFBP7 ITGA10 ITGA11 ITGA8 ITGB5 KANK1 KCNK15 KCNK17 LDOC1 LGR6 LIMS4 LOXL1 LTBP1 LTBP2 LTBP3 MAN2B2 MEGF6 MFGE8 MGP MRAP2 MYH10 MYH9 MYO1D NOX4 NPR1 NXPH3 OGN OMD OSR1 PCDH7 PCDHB11 PDGFD PID1 PKD2 PLD5 PLS3 PMEPA1 PRDM16 PRDM6 PRKG1 PRRX2 PTGIR PTGIS PXDC1 SCUBE3 SMOC2 SNX18 SOD3 SOST ST6GAL2 STAC STK38L SULF1 SUSD5 TBXA2R THBS2 THRB THSD7B TMEM47 TNFRSF11B TPH1 VCAN WWP2 ZNF385D Heart - Atrial Appendage Female 40-49 Up ACTC1 ADAMTS7 ADAMTSL2 ADGRD1 ALPK2 ANKRD1 ASPG BCO2 BMP10 C14ORF180 CASQ2 CCDC141 CHRNE CIB2 CORIN COX7A1 CPNE5 CRIP2 CSDC2 CSRP3 CYP2J2 DAND5 DHRS7C DKK3 DOK7 FABP3 FBXO40 FGF12 FGF23 FITM2 GATA4 GRXCR2 HCN4 HHATL HRC HSPB2 HSPB3 HTRA3 IGSF5 ITGB1BP2 KCNIP2 KLHL31 KRBA1 LAPTM4B LRRC10 METTL7B MPP3 MT1HL1 MYBPC3 MYBPHL MYH6 MYL4 MYL7 MYLK3 MYOZ2 MYZAP NDUFA4 NDUFAB1 NEBL NES NKX2-5 NKX2-6 NMRK2 NPPA NPPB NRTN OR10P1 OTOGL PAM PLA2G2A PLA2G5 POPDC2 PRKAG2 PRR32 PXDNL RABGAP1L RBM20 RBPMS2 RD3L RILPL1 RNF207 RYR2 SBK2 SBK3 SCN5A SHD SLC25A4 SLC41A1 SLC4A3 SLC8A1 TBX20 TBX5 TECRL TMEM182 TNNI3K TNNT2 TRIM55 UQCRB WNK2 XIRP1 Heart - Left Ventricle Female 40-49 Up ACTC1 ANKRD1 ASB18 BCO2 BZW2 CASQ2 CCDC141 CDH2 CHCHD10 CKMT2 COQ10A COX5A COX7A1 COX7B CPT1B CRYAB CSDC2 CSRP3 CYP2J2 DAND5 DECR1 ECSIT ERVMER34-1 ETFDH FABP3 FGF18 FHL2 FHOD3 FITM2 FLNC GATA4 GJA3 GOT1 GRIP2 HHATL HRC HSPB3 HSPB7 ITGB1BP2 KLHL31 LARGE1 LRRC10 LSMEM2 MAPKAPK3 MDH1 MFN2 MLYCD MPC1 MT1HL1 MTUS2 MYBPC3 MYH7 MYH7B MYL2 MYL3 MYLK3 MYOZ2 MYZAP NDUFA1 NDUFAB1 NDUFS6 NEBL NKX2-5 NMRK2 OGDH OXCT1 PDE1C PDHA1 PKP2 PLN POPDC2 PPM1K PTDSS1 RBM20 RD3L RNF207 RYR2 SCN10A SCN5A SDHA SLC25A4 SLC41A1 SLC4A3 SLC8A1 SMCO1 SMPX SMYD1 SMYD2 SRL TCF15 TECRL TENM2 TNNI3 TNNI3K TNNT2 TPM1 TRIM55 UQCRC1 XIRP1 XPR1 Artery - Coronary Female 40-49 Up ACTA2 AEBP1 AMIGO2 ANTXR1 AOC3 ARL4AP5 ASPN ATP10A BCAM BGN C1QTNF1 C1QTNF2 CCDC190 CCDC3 CD151 CHURC1 CMKLR1 CNNM2 COL14A1 COL18A1 COL21A1 COL4A1 COL4A2 COL4A4 CPED1 CPXM2 CRIP1 CRIP2 CRLF1 CSRP2 ECM2 EFEMP1 FBLIM1 FMOD FOXL1 FOXS1 FRK FRY GJA5 GPR20 HAPLN1 HEYL HTR1B ID4 IGFBP7 IL33 INAFM2 ITGA1 ITGA8 JAG1 KCNA5 LDOC1 LGI2 LGR6 LRRC17 LTBP1 MCAM MFAP4 MFGE8 MSC MTHFD1L MUSTN1 NT5DC2 NTF3 NTRK3 OGN OMD PAWR PCDHB16 PCDHB9 PCOLCE2 PCSK7 PDE1A PDGFA PKIG PPP1R14A PRDM16 PRKG1 PTGIS RRAS RSU1 S1PR3 SMIM10 SORT1 ST6GAL2 ST6GALNAC5 STK38L SUSD2 SUSD5 TAGLN TBX18 TBX2 TBXA2R TGM2 THBS2 TNFRSF11B TRABD2B VCAN WFDC1 WTIP Uterus Female 40-49 Up ABCD1 ADAM33 ADAMTS19 ADAMTSL5 AKAP13 ALDH1A2 ALX3 ATP2B4 BAG2 BNC2 CDH24 CDKL1 CEP135 CHRDL2 CTTNBP2 CUX1 DCHS1 DPP6 EMX2 ENPP1 EPHB4 ESR1 FBXL22 FRMD7 GAS1 GATA2 GJC1 GNA14 GPR161 GUCY1A2 HOXA10 HOXA11 HOXA6 HOXD10 HOXD11 HOXD3 HOXD4 HOXD9 HUNK IL17RD ISLR ISOC1 KCNG1 KCNMA1 KDR KLHL13 LCN6 LEFTY2 LINGO2 MAMDC2 MASP1 MEIS1 MEIS3 MFAP5 MITF MOXD1 MRGPRF NXNL2 OSR2 PBX1 PGR POMGNT2 PRLR PTGER3 PTK7 RAB11FIP2 RAD51B RAMP1 RAP2C RERG REV3L RSPO1 SERTM1 SLC24A3 SLC37A3 SNAPC2 SNCAIP SPON2 SSC5D STK26 SULF2 SUPT20HL1 SYTL4 TAB3 TBC1D1 TBL1X TCEAL1 TCEAL4 TCF23 TGFB1I1 TMEM123 TMEM158 TMEM200A TMEM200B TNFAIP8L3 TRPC4 TSHZ3 WT1 ZDHHC14 ZNF516 Breast - Mammary Tissue Female 40-49 Up ABCB5 ADGRD2 AFP ALX4 ANKRD30A ANO1 ARHGEF38 ATP13A5 AUTS2 C1ORF226 CCDC8 CCL28 CITED4 CLDN8 CMTM7 CRACR2B CX3CL1 CYP4Z1 ELF5 ETV3L GABRP GSC HCAR1 IL17RD IL22RA2 IRX1 IRX2 IRX3 IRX5 KIT LAMC2 LMX1B MAML2 MMP7 NFIB NTN4 OBP2B OVCH2 OXTR PLEKHS1 PROM1 SAV1 SCUBE2 SFRP1 SLC26A5 SLC28A3 SLC39A6 ST8SIA2 STAC2 TANK TBC1D9 TCF7L2 TFAP2B TFAP2C TIGD2 TRPS1 TSHZ2 VGLL1 VTCN1 Cells - EBV-transformed Lymphocytes Male 50-59 Up AICDA ANGPTL6 APOBEC3G APOBEC3H ATAD5 B3GNT2 BATF BFSP2 BLNK BTLA CCL3L3 CCNI2 CCR7 CD226 CD274 CD40 CD48 CD70 CD79A CD80 CD86 CLEC17A CLNK CPOX EAF2 EBI3 EDEM1 ENTPD1 FAM111B FAM72B FAM72D FCER2 FCRLA FSBP GCSAM GNGT2 GPR15 HLA-DQA1 HVCN1 IFI44L IFIH1 IFNA2 IKZF2 IL21R IL4I1 IRF4 IRF5 LGALS14 LPXN LTA LY75 MAP4K1 MCM2 MCOLN2 MS4A1 MX1 MYL12BP2 NEK6 NEUROG2 NFKBIE OAS2 OAS3 P2RY10 PAX5 PI4K2B PIF1 PIK3R6 PMAIP1 PNOC POU2AF1 PTPN22 RAD54B SCIMP SEMA7A SIT1 SLAMF1 SLAMF6 SLAMF7 SPIB SPN STAP1 STAT1 TEC TIFA TLR10 TLR7 TMSB15B TNF TNFRSF13B TNFRSF17 TNFRSF8 TNFSF11 TNFSF9 TRAF1 TSPAN33 TTF2 WDFY4 WNT10A ZC3H12D ZNF318 Cells - EBV-transformed Lymphocytes Male 40-49 Up ANGPTL6 AP1S3 APOBEC3G APOBEC3H ATAD5 B3GNT2 BATF BFSP2 BLNK BTK BTLA CCL3L3 CCNI2 CCR6 CD226 CD27 CD40 CD48 CD70 CD79A CD80 CLEC17A E2F7 EBI3 EDEM1 EIF2AK2 FAM72B FAM72D FCER2 FCRLA GCSAM GNGT2 GPR15 GPR55 HLA-DQA1 HVCN1 IFI44L IFIH1 IKZF2 IKZF3 IL21R IL4I1 IRF4 IRF5 ITGA4 LPXN LTA LY75 MAP4K1 MCM2 MCOLN2 MS4A1 MX1 MYL12BP2 NEUROG2 NFKBIE NT5C3A NUP210 OAS2 OAS3 P2RY10 PAX5 PI4K2B PIK3R6 PLCG2 PMAIP1 PNOC POU2AF1 POU2F2 PTPN22 RAD54B SCIMP SEMA7A SIT1 SLAMF1 SLAMF6 SLAMF7 SNX25 SPN STAP1 STAT1 TCL1A TEC TIFA TLR10 TLR7 TMSB15B TNF TNFRSF13B TNFRSF17 TNFRSF8 TNFSF11 TNFSF9 TTF2 USP18 WDFY4 WNT10A ZC3H12D ZFAT ZNF318 Spleen Male 40-49 Up ABI3 AIF1 ARHGAP4 BANK1 BLK C1QA C1QB C1QC CABP4 CARD9 CCL24 CCM2L CCR5 CD163L1 CD180 CD19 CD1C CD1D CD22 CD33 CD4 CD5L CD72 CD79B CD8A CERKL CETP CNR2 CR2 CSF1R CXCL13 CXCL6 CXCR5 CXCR6 DLL1 EMID1 EPHA8 EXOC3L1 FCMR FCRL1 FCRL2 FCRL3 FGD2 FHOD1 FLI1 GAB3 GDPD2 GDPD5 GIMAP1 GPR182 GRAP GSDMD HLA-DOB HMOX1 HYAL1 HYAL2 IL10RA IL24 IRF8 ITGAD KAZALD1 LILRA4 LILRB1 LILRB5 LRTM1 LTB MFNG MPEG1 MS4A7 NLRC3 NOS3 NOX5 NPY1R NR5A1 OR5AK2 P2RX5 P2RY6 P3H2 PARP15 PARVG PDE6G PLCB2 PPM1N PSTPIP2 RENBP S100Z SCN11A SIGLEC12 SPIC STAB1 STAB2 TDGF1 TLX1 TMC8 TMEM26 TNFRSF13C TRAPPC3L TTC24 UNC93B1 VCAM1 Artery - Aorta Male 40-49 Up ADAMTSL3 ADRA1B ADRA1D ADRA2C AEBP1 ANO1 ANTXR1 BGN C1QTNF8 C8ORF34 CD151 CDH13 CNTN4 COL14A1 COL21A1 CPXM2 CRISPLD1 EFEMP1 ELN EXT1 FAM180A FBLIM1 FBLN5 FGL2 FIBIN FMOD FOXC1 FOXC2 FRZB GABRR1 GAS6 GDF7 HAPLN3 HAUS7 HMCN1 IGFBP2 IGFBP7 ITGA10 ITGA11 ITGA8 ITGB5 KALRN KANK1 KCNK15 KCNK17 LDOC1 LGR6 LIMS4 LOXL1 LTBP1 LTBP2 LTBP3 MAN2B2 MEGF6 MFAP4 MFGE8 MGP MICAL2 MRAP2 MYH10 MYH9 MYO1D NAV1 NAV2 NOX4 NPR1 NXPH3 OGN OMD OSR1 PCDH7 PCDHB11 PDGFA PDGFD PID1 PKD2 PLD5 PLS3 PRDM16 PRDM6 PRKG1 PTGIR PTGIS PXDC1 SCUBE3 SMOC2 SOD3 SOST ST6GAL2 SULF1 SUSD5 TBXA2R TC2N THBS2 THSD7B TNFRSF11B TPH1 VCAN WWP2 ZNF385D Pancreas Male 40-49 Up AKR7A3 AMY1B AMY1C AMY2A AMY2B ANXA4 AQP12A AQP12B AQP8 ARL5C BHLHA15 BNIP3 CEL CELA2A CELA2B CELA3A CELA3B CFTR CLDN10 CLPS CLPSL2 CPA1 CPA2 CPB1 CTRB1 CTRB2 CTRC CTRL CUZD1 EPB41L4B ERICH5 ERO1B ERP27 FAM3B FBXW12 FKBP11 G6PC2 GATM GCG GLP1R GNMT GP2 GPHA2 GPR150 GRPR GUCA1C HOMER2 IAPP IL22RA1 INS KCNK16 KIRREL2 KLK1 LENG9 LHFPL5 MNX1 NPHS1 NR5A2 ONECUT1 OR10G4 OR4D5 OR6M1 OR8D4 P4HB PDCD4 PDIA2 PDX1 PGGHG PKHD1 PLA2G1B PNLIP PNLIPRP1 PNLIPRP2 PRDX4 PRSS1 PRSS2 PRSS3 PTF1A RBPJL REG1A REG1B REG3G RNF186 SCTR SEL1L SERPINI2 SLC30A2 SLC30A8 SLC38A5 SLC39A5 SLC43A1 SLC4A4 SPINK1 SYCN TECPR1 TMED6 TMEM97 TPST2 TRPV6 XBP1 Adrenal Gland Male 40-49 Up AADAC ABCB1 ABCC3 ABCF3 ADGRV1 AKAP7 AKR1B1 ALAD ALAS1 ALKAL2 AMHR2 AOX1 AQP11 AS3MT ASB4 C2CD2 C4B CELA1 CLRN1 CREBL2 CTNNAL1 CTSA CYB561A3 CYB5B CYP11A1 CYP11B1 CYP17A1 CYP21A2 DBH DEXI DHCR24 DLK1 EPHX1 ERN1 FAM166B FAM43B FBXO9 FDX1 FDXR FNDC4 GALM GNPTG GNS GRAMD1B GSTA1 GSTA3 GSTA4 HDHD3 HSD3B2 IDH1 IFITM10 KCNJ5 KCNK3 KCNN2 KCNQ1 KCTD14 KLHDC8B KLHL4 LONP1 MAP3K15 MAP3K5 MC2R MCOLN3 MGARP MRAP NR0B1 NR5A1 PAPSS2 PEBP1 PHOX2A PLBD2 PLEKHA5 POR PORCN RARRES2 RBBP7 RDX RGN RMDN2 SCAP SCARB1 SEMA6A SERPINA5 SLC16A9 SLC23A2 SLC40A1 SLC47A1 SLC8B1 SNTB1 SOAT1 SREBF1 STAR TBX3 TM7SF2 TMEM150C TSPAN12 VWA5B2 WHRN ZNF275 ZNF280A Minor Salivary Gland Male 40-49 Up AGFG2 ALDH1A3 AMTN ANKRD36C APCDD1L ASCL3 AZGP1 BACE2 BARX2 BIK BPIFB2 C4ORF19 C6ORF58 CCDC160 CCL28 CD46 CEP41 CHI3L2 CHPT1 CHST9 CLDN10 CRACR2A CRACR2B CRISP3 CXCL17 DEFB1 DNASE2B DUSP23 EHF ELF5 ENPP3 FAM3D FBN3 FDCSP FUT2 GALNT4 GALNT6 GDF5 GLYATL2 GPRC6A HTR3A IRX2 JCHAIN KCNN4 KRT23 KRT7 LCN2 LHX8 LPO LRRC26 LTF LYZ MGAM2 MLPH MMP7 MUC16 MUC19 MUC5B MUC7 NAALADL2 NKX2-6 ODAM OTX1 PAX3 PIGR PIP PLEKHS1 PLPP2 PROM1 RAD51B RHD RNF183 RUNX1 SCNN1A SH3BP4 SLC28A3 SLC6A14 SLFN13 SLITRK6 SLPI SOX9 SPDEF TCN1 TFCP2L1 TMC5 TMED3 TMEM200C TMEM63A TNFRSF11A TNFSF15 TOX3 TRPV4 VGLL1 VTCN1 WFDC2 WWC1 XBP1 ZG16B ZNF552 ZSWIM4 Esophagus - Mucosa Male 40-49 Up A2ML1 ADH7 ALDH3A1 ANXA1 AQP3 BARX2 CALML3 CAPN1 CAPN14 CLCA2 CRABP2 CRNN CSTA CSTB CYSRT1 DSC2 DSG3 DYNAP ECM1 EMP1 ENDOU EPGN EPHA1 ERO1A ESPL1 EVPLL FABP5 FAM83A FGFBP1 FUT6 GBP6 GJB2 GJB6 GPR78 GRHL3 GSTP1 IGFL1 IL1RN KLK10 KLK12 KLK13 KRT13 KRT15 KRT4 KRT6A KRT6B KRT6C LYPD2 MALL MPZL2 MUC21 NMU OTOP3 PADI1 PAX9 PITX1 PPL PRSS27 RAB10 RAB25 RAET1E RAET1G RAET1L RHCG RHOD RNF223 S100A14 S100A16 S100A2 S100A8 SAMD9 SERPINB13 SERPINB2 SERPINB3 SFN SMAGP SPINK5 SPRR1A SPRR2A SPRR3 TACSTD2 TGM1 TGM3 TMEM184A TMEM40 TMPRSS11A TMPRSS11B TMPRSS11E TMPRSS11F TMPRSS4 TRIM16 TTC22 TTC9 TTLL12 TXN TXNDC17 UGT1A7 USH1G VSIG10L ZNF185 Brain - Frontal Cortex (BA9) Female 40-49 Up ADCY1 AK5 ATRNL1 C11ORF87 C1QL3 C3ORF80 CABP1 CAMK2A CAMK2N1 CBLN2 CBLN4 CCK CHN1 CNTNAP2 CNTNAP5 COL26A1 CREG2 CTXN3 DLGAP1 DPP10 ELAVL4 ENC1 EPHA5 FAM163B FAM81A FREM3 FRMPD4 GABBR2 GABRA1 GABRG2 GPR26 GRIN2A GRM5 HAPLN4 HCN1 HECW1 HS6ST3 HTR1A HTR2A HTR3B KCNC2 KCNH1 KCNH5 KCNS1 KCNS2 KCNV1 KCTD16 KIAA1549L KIF3C KIF5A LINGO1 LRFN2 LRRTM4 MAPK10 MCHR2 MGAT5B MPPED1 NCALD NEFL NELL1 NELL2 NLK NPBWR2 NRCAM NRG3 NXPH2 OLFM1 OLFM3 OPRD1 OR14I1 PCDH8 PCDHA5 PCDHGC5 PDXP PNMA2 POU6F2 PPFIA2 PTPRT R3HDM1 RAB6B RGS4 RIMS3 RORB RPH3A SERPINI1 SGTB SHANK1 SHC3 SLC4A10 SLITRK1 SYT1 SYT13 SYT16 TBR1 TESPA1 TMEM132D USP17L22 VSNL1 VSTM2A ZNF365 Brain - Cerebellar Hemisphere Female 40-49 Up ADAM22 AKAIN1 ALS2 BARHL1 BARHL2 BSPH1 CA10 CACNA1A CADPS2 CALN1 CAMK4 CAMKK2 CBLN1 CBLN3 CCDC175 CCDC177 CHD7 CHN2 CHRNA6 CLVS2 CNPY1 CNTN6 COL13A1 CRTAM DIRAS2 DISP2 EN2 ETV1 FAM131C FAT2 FSTL5 GABRA6 GALNT13 GCSAML GPR137C GPR158 GRIA4 GRIK2 GRM1 GRM4 KCNA1 KCNC1 KCND2 KCNJ3 KCNK9 KLHL3 LCN8 LGALS16 LHX1 MAB21L1 MEGF11 MKRN2OS MMP24 MTCL1 MYT1 NEUROD1 NEUROD2 NPFFR1 NREP NRXN3 OR1F1 PAK5 PAX6 PCDHA5 PCDHA8 PCDHGC4 PKIB PPFIA4 PPM1H PRSS51 PSD3 RAB37 RELN RIMS1 RIT2 SHF SOGA1 SPHKAP SRGAP2B SRRM3 ST8SIA5 STH SYT2 SYT4 SYT9 TIAM1 TMC2 TMEM178A TRIM67 TRPM3 VSX1 XKR7 ZBTB18 ZIC1 ZIC2 ZIC3 ZIC4 ZIC5 ZNF382 ZNF521 Brain - Nucleus Accumbens (Basal Ganglia) Female 40-49 Up ACTR3B ADORA2A AKAP5 AMBN AMZ1 ANKRD34B ANKRD63 ARPP21 C1QTNF4 C4ORF50 CACNA1E CACNG4 CAMKV CNMD COCH CPNE5 CRYM CTXN1 CYP46A1 DACT2 DLL3 DLX6 DRD1 DRD2 DRD3 DTNBP1 FAT3 FBXL16 GABRA5 GAD2 GNAL GNG7 GPR101 GPR139 GPR149 GPR27 GPR52 GPR6 GPR85 GPR88 HPCA HRH3 HTR1D HTR2C HTR6 IDNK IMPG1 JAKMIP1 KCNA4 KCNH4 KCNIP1 KCTD4 KIRREL3 LAMP5 LHFPL3 LMTK3 LRRC7 LRRTM1 LYPD1 MINDY4B MMD NCDN NECAB2 NKAIN4 NTSR2 OPRK1 OTOF PCDH11X PCP4 PCP4L1 PDE1B PDYN PHACTR1 PIANP PLPPR1 PLPPR3 POU3F4 PPP1R1B PRKCG PTPN5 RAB40B RESP18 RGS14 RGS20 RGS8 RPRML SH2D5 SHISA7 SIX3 SLC32A1 SLC9A7 SOWAHA SOX11 SV2C SYNDIG1L SYNPR THRA TMEM158 WNT1 WNT10B Brain - Putamen (Basal Ganglia) Female 40-49 Up ACBD7 ADORA2A AMBN AMER2 ANO3 AQP4 ASIC1 ASRGL1 ATP1A2 BAALC BCAN CABLES1 CACNG4 CDH20 CGB2 CHAT CLDN6 CORT CPLX1 CTNND2 CTXN1 CYP46A1 DEFB107B DLX6 DRD1 DRD2 EFR3B ENHO ENTPD3 ETNPPL EYA1 FAM171B FBXL16 FOXE3 GABRA2 GBX2 GNAO1 GNG7 GPC5 GPR85 GPR88 GRM3 HCN2 HEPACAM HIPK2 HPCA HRH3 HS3ST5 KCNH4 KCNJ14 KCTD17 LRRC10B LRRC3B LRTM2 MAPK4 MEGF10 METRN MMD2 MYO10 NGEF NKAIN4 NOS1 NPY NR2E1 NRGN OLFM2 ONECUT2 OPALIN OR5AN1 PCP4 PDE10A PDE1B PHLPP1 PITPNC1 PPIAL4G PPP1R1B PSD2 PTPRZ1 RANBP3L RASD2 RGS14 RGS20 RGS9 SCN4B SLC18A3 SLC1A2 SLC1A3 SLC24A2 SLC25A23 SLC39A12 SLC5A7 SLC6A1 SLC6A12 SLCO1C1 SP9 SYNDIG1L TECTB TMEFF1 TRIM64C TRPC3 Brain - Hypothalamus Female 40-49 Up ACHE AIRE B3GAT2 BSX C12ORF76 CALB2 CALCR CALY CAMK2N2 CENPVL1 CENPVL2 CLEC19A CNGB1 CRHBP CSMD3 CTXN2 DIRAS3 DLL3 DLX1 DNER DSCAM ECE2 ELAVL2 ELSPBP1 ERAS FOXB1 GABRG3 GABRQ GNG4 GNG8 GPR21 GPR45 GRIK1 GRIN2D HAP1 HCRT HCRTR2 HDC INPP5F KLHL1 KLHL32 LGALS16 LHFPL3 LHX5 LRRC55 LUZP2 LYPD6 MAGEL2 NAP1L3 NAP1L5 NGB NXPH1 OLIG1 PABPC1L2A PABPC1L2B PARPBP PEG10 PIRT PMCH PNMA5 PODXL2 PSMD10 QRFPR R3HDML RAB3C RND2 RPE65 RTL1 RTP5 SCG2 SCN3A SCOC SLC17A6 SLC35D3 SLC6A11 SLCO1A2 SMIM10L2A SMIM10L2B SMIM17 SMIM18 SNCG SOX11 SPOCK3 SV2C SYNGR3 SYT6 SYTL5 TACR3 TCEAL7 TMEFF1 TMEFF2 TMEM17 TMEM255A TNR TUBB3 UCHL1 VAT1L VSTM5 VWC2L ZBTB8B Brain - Cerebellum Female 40-49 Up ADAM11 ALS2 ANKS6 ARHGEF33 BARHL2 CACNA1A CACNA1G CAMK4 CAMKK2 CARMIL3 CCDC175 CDH15 CECR2 CELSR3 CKMT1B CLK4 CLVS2 CNPY1 COL13A1 CRTAM DISP2 EPB41 FAM131C FAT2 FGF17 FGF3 FUT9 GNG13 GPR137C GRID2 GRID2IP GRIK2 GRIN2C GRM1 GRM4 IFNA8 KCNAB3 KCNC1 KCNK9 KCNT1 KLHL3 LCN8 LDLRAP1 LHX1 MDGA1 MEGF11 MMP24 MTCL1 MYT1 NBPF20 NPFFR1 OR1F1 PAX6 PKD1 PLEKHD1 PPFIA4 PPIP5K1 PPP1R17 PRR35 PRSS51 PVALB RAB37 RGS11 RNF112 SBK1 SHF SHISA8 SKOR1 SLC1A6 SLC22A31 SLC35F4 SOGA1 SRRM3 SRRM4 ST8SIA5 STRC STXBP5L TENM1 TFAP2E TLE2 TMC2 TMEM120B TMEM145 TMEM151B TMEM178A TMEM266 TRANK1 TRIM11 TRIM67 TRIM9 TRPM3 WSCD2 XKR7 ZFYVE28 ZIC3 ZIC4 ZIC5 ZNF382 ZNF493 ZP2 Brain - Cortex Female 40-49 Up ADGRA1 ADGRB1 ADGRB2 ANKRD24 ATCAY BHLHA9 BRINP2 BRSK1 C2CD4C CABP1 CAMK2A CBLN2 CCK CHD5 COL26A1 CUX2 DAGLA DAOA DPF1 EIF4E1B ELFN2 FAM163B FBXO41 FXYD7 GRIN1 HAPLN4 HECW1 HS3ST4 HTR3B KCNAB2 KCNH3 KCNH5 KCNJ4 KCNS1 KCNS2 KIF1A KIF5A KRTAP25-1 LCN15 LHX2 LINGO1 LRFN2 LYNX1 MAP1A MAST3 MCF2L2 MCHR2 MGAT5B MPPED1 NCALD NRGN OLFM1 OPRD1 OR10X1 OR14I1 OR1A1 OR1D4 OR4A5 OR4C16 OR4C45 OR4C5 OR4K14 OR4K2 OR4K3 OR4K5 OR5AL1 OR5D14 OR5H1 OR5T3 OR5W2 OR6C75 OR6K2 OR6Y1 OR8B4 OR8H1 PACSIN1 PDXP PHF24 PI4KA POU6F2 PRKAR1B PTPRT RAPGEF4 RIMS3 RNF208 RORB RPH3A SHC3 SLC17A7 SLC6A17 SNPH SOHLH1 SPRN STX1A SYN1 TBR1 TESPA1 TRIM49D2 TSPOAP1 UNC5A Pituitary Female 40-49 Up AHI1 ALK ARFGAP1 ARHGAP36 ASIC4 BAIAP3 C14ORF39 C17ORF107 C21ORF58 C2CD4A C2ORF15 CDKN2A CDRT4 CELF3 CFAP47 CFC1 CGA CHGB CHST8 CLDN25 CNGA3 COL11A2 COL22A1 COL9A2 CSH2 CSHL1 CUL7 DGKK DRD2 FAM163A FBXO16 FSHB GALR1 GCK GH1 GH2 GHRHR GHSR GJB7 GNB3 GNRHR GPR148 GPR50 HFM1 HLA-G HTATSF1 IGSF1 INSM1 IRS4 KSR2 LHB LHX3 MDK MYO15A NAALAD2 NEUROD4 NNAT OR13C2 OR13C5 OR13C9 OTOS PCDHB1 PHF21B PLD3 POU1F1 PRL PRLHR PROP1 PTPRN RAX2 REC8 RIIAD1 RIMBP2 RNF224 RPH3AL SCG5 SIX6 SYNGAP1 TAC4 TBX19 TCP11X1 TCP11X2 TGFBR3L TMEM244 TMEM61 TPH2 TRHR TRPC3 UBTFL1 UGT2A1 UGT2A2 VMO1 VWA5B1 VWA7 VWDE ZFR2 ZNF10 ZNF667 ZP1 ZSCAN1 Kidney - Cortex Male 50-59 Up ACMSD ACY1 ACY3 AGMAT AGXT2 ALDOB AQP2 AQP6 ATP6V0A4 ATP6V0D2 ATP6V1B1 ATP6V1G3 BBOX1 BPHL BSND C11ORF54 CDH16 CLCNKB CLDN16 CLDN2 CLEC18B CLEC18C CRYAA CRYL1 CUBN CYS1 DCDC2 DDC DHDH DMRT2 DUSP9 EMX1 FMO1 FOXI1 FOXI2 FXYD2 FXYD4 GGACT GLYAT HNF1B HOGA1 HOXB6 HOXD8 KCNJ1 KCP KIF12 KL LY6L LYG1 MCCD1 MIOX MSRA NAT8 NPHS1 NPHS2 OGDHL OR2T10 PAX2 PDZK1 PDZK1IP1 PKHD1 PODXL PRODH2 PTH1R PTPRO RBP5 REN RHBG SLC12A1 SLC12A3 SLC13A3 SLC16A4 SLC17A1 SLC17A3 SLC22A11 SLC22A12 SLC22A13 SLC22A2 SLC22A24 SLC22A6 SLC22A8 SLC34A1 SLC34A3 SLC3A1 SLC47A2 SLC4A9 SLC5A10 SLC5A12 SLC5A2 SLC6A13 SLC7A13 TINAG TMEM174 TMEM207 TMEM213 TMEM52B TMEM72 UGT1A9 UGT2B7 UPP2 Brain - Frontal Cortex (BA9) Female 50-59 Up ADGRA1 AGBL4 AK5 ANKRD24 ATRNL1 BHLHA9 C11ORF87 C3ORF80 CABP1 CACNG3 CAMK2N1 CBLN2 CCK CHN1 CLEC2L COL26A1 CREG2 CRYGA DLGAP1 DPP10 EIF4E1B ELAVL4 ENC1 EPHX4 ERC2 FAM163B FAM81A FXYD7 GABBR2 GALNT8 GAP43 GLRB GRIA3 GRIN2A HCN1 HECW1 HS3ST4 HTR1E HTR2A KCNC2 KCNH5 KCNS1 KCNS2 KCNV1 KCTD16 KIAA1549L LINGO1 LMO4 LRFN2 MAPK10 MCHR2 MPPED1 NANOS3 NAP1L2 NAPB NCALD NECAB1 NEFL NEFM NELL1 NELL2 NLK NPBWR2 NRCAM NRGN OLFM1 OLFM3 PNMA6A POU6F2 PRKAR1B PTPRT RAB3A RFPL2 RGS4 RNF208 RORB RPH3A RTN3 RXFP1 SCG3 SCN1A SERPINI1 SLC17A7 SLC35F1 SLITRK1 SNCB SOHLH1 STMN1 STX1A SULT4A1 SYN1 SYP SYT1 TBR1 TESPA1 TMEM132D VSNL1 YWHAH ZDHHC22 ZNF365 Brain - Cerebellar Hemisphere Female 50-59 Up ACAP3 ALS2 ANKRD18B BARHL1 BARHL2 BRICD5 CA10 CACNA1A CBLN1 CBLN3 CDH15 CDH22 CERS5 CHN2 CKMT1B CNPY1 CRTAM DISP2 EGR4 EN2 ETV1 FAM131C FGF17 FGF3 FSTL5 GABRA6 GABRD GALNT9 GCSAML GPR83 GRIK2 GRIN2C GRM4 IGLON5 KCNAB3 KCNC1 KCNK9 LHX1 MDGA1 MTCL1 MYT1 NBPF20 NEUROD1 NEUROD2 NKX6-3 NPAS4 NPIPA2 NREP NRXN2 NRXN3 OTX2 PAX6 PKIB PLGLB1 POLB PPFIA4 PPIAL4C PRR35 PTH2 RAB26 RAB37 RBFOX3 RELN RGS11 RIT2 SHF SHISA8 SLC22A31 SLC35F4 SLC6A7 SLC8A2 SOGA1 SRGAP2 SRRM3 SRRM4 TAS2R4 TFAP2E TIAM1 TLX3 TMC2 TMEM145 TMEM178A TMEM266 TNFRSF25 TRIM11 TRIM67 TUBA8 UBAP1L UNCX VAX2 VSX1 WFIKKN1 XKR7 YPEL4 ZBTB18 ZIC1 ZIC2 ZIC4 ZIC5 ZNF30 Brain - Substantia Nigra Female 50-59 Up ADARB2 ALDH1A1 ANKRD40 APBA1 BAALC BCAS1 C18ORF32 CADPS CDH8 CHRNA6 CHRNB3 CLDND1 CLEC19A CTNNA3 DBX2 DNAJC6 DNER DOK6 DYNC1I1 DYNC1LI2 ELAVL2 EN1 ERMN FAM219A FGF1 FOXB1 GALNTL6 GFAP GLRA1 GPR26 GSG1L HCRTR2 HIPK2 HMX1 KCNE5 KCNG4 KCNJ6 KIF6 KLHL1 LACC1 LHPP LMX1B LPAR1 LRRC55 LUZP2 MBP MOBP MTURN NEFL NIPA1 NTSR2 OC90 OLIG1 P2RY12 PAAF1 PAIP2B PAQR6 PHYHIPL PIRT PKP4 PLCXD2 PLEKHB1 PMP2 POU3F2 QDPR RAB3C RET RND2 ROM1 RPE65 RSPO2 SCD5 SH3GL3 SHTN1 SIAH3 SLC10A4 SLC15A5 SLC18A2 SLC2A13 SLC5A11 SLC6A11 SLC6A3 SLCO1A2 SMIM10L2B SNCG SNX10 SPOCK3 SPX SV2C TH TMEM200C TMEM255A TP53INP2 TRIM41 TSC22D4 TUB TUBB2B TUBB3 VWC2L ZAR1 Brain - Caudate (Basal Ganglia) Female 50-59 Up ACSBG1 ADCYAP1R1 ALDH7A1 AMBN ANKRD34B ANO3 AQP4 ARPP19 ATP1B2 BAALC C1QTNF4 CABLES1 CACNG4 CDH20 CERS1 CHAT CHI3L1 CORT CPE CRB2 CSAG1 CST3 CTXN1 CYP46A1 DDAH1 DGKB DRD1 EFR3B ETNPPL FAM171A1 FBXL16 GABRA2 GABRA4 GABRG1 GAREM2 GNG7 GPC5 GPR143 GPR37L1 GPR75 GPR88 GRM3 HEPACAM HHIPL1 HPCA HS3ST5 HTR6 KCNH4 KCTD17 LGI1 LIX1 LRRC10B LRRN1 LRTM2 LYPD1 MAPK4 METRN MLC1 MT3 NCAN NDP NGEF NPAS3 NR2E1 NTRK2 NTSR2 ONECUT2 PCP4 PDE10A PDE1B POU3F4 PPP1R1B PPP3CA PSD2 PTPN5 PTPRZ1 RASD2 RESP18 RGS14 RGS20 RGS9 RIC8B RLBP1 SCN4B SFXN5 SIX3 SLC1A2 SLC1A3 SLC25A18 SLC25A23 SLC35D3 SLCO1C1 SP9 SPEF1 STON2 SYNDIG1L TAC1 TTYH1 TUBB2B VAX1 Brain - Nucleus Accumbens (Basal Ganglia) Female 50-59 Up ACTR3B AKAP5 ANKRD34B ANKRD63 ARPP21 C1QTNF4 C4ORF50 C6ORF141 CACNA1E CACNG4 CAMKV CDH9 COCH CPNE5 CRYGA CRYM CSMD3 CYP46A1 DACH2 DLX6 DRD1 DRD3 EFNB3 ELMOD1 FAT3 GABRA4 GABRA5 GAD2 GNAL GNG7 GPR101 GPR149 GPR27 GPR52 GPR6 HRH3 HS6ST2 HTR1D HTR2C HTR6 ICAM5 IMPG1 JAKMIP1 KCNA4 KCNH4 KCNIP1 KCNK18 KCNK4 KCTD4 KHDRBS2 KIRREL3 LAMP5 LINGO3 LRRC7 LRRTM1 MAPK1 MINDY4B NAT16 NCDN NECAB2 OPRK1 OTOF PCDH11X PCDHGC5 PCP4L1 PDYN PENK PHACTR1 PIANP PLPPR1 PLPPR3 PNMA5 POU3F4 PRKCG PRMT8 PTPN5 PTPRO RAB40B RAP1GAP RESP18 RGS20 RGS8 RPRML SEZ6 SH2D5 SHISA7 SIX3 SLC32A1 SLC9A7 SNX32 SORCS3 SOWAHA SPINK9 SV2C SYNPR SYTL5 THRA TMEM158 WNT1 WNT10B Brain - Putamen (Basal Ganglia) Female 50-59 Up ADORA2A ALDH7A1 AMBN AMER2 ANKRD34B ANO3 ARPP19 ARPP21 ASPHD1 ATP1B2 BAALC CACNG4 CERS1 CHAT CHST6 CNDP1 CORT CSAG1 CST3 CTNND2 CTXN1 CYP46A1 DACT2 DGKB DLX6 DRD1 DRD2 EFR3B ENTPD3 ETNPPL EYA1 FAM171A1 FBXL16 FGF1 GBX2 GNAO1 GNG7 GPR52 GPR6 GPR88 GPRC5B GRM3 HCN2 HDAC11 HIPK2 HPCA HRH3 HS3ST5 HTR1D JAKMIP1 KCNH4 KCTD17 LRRC10B LRTM2 MEGF10 METRN MLC1 MT3 NGEF NKAIN4 NRGN ONECUT2 OPALIN OTOF PCP4 PDE10A PDE1B POU3F4 PPP1R1B PPP3CA PSD2 PTPN5 QDPR RAB11FIP4 RAB40B RASD2 RESP18 RGS14 RGS20 RGS9 RLBP1 ROM1 SCN4B SFXN5 SHTN1 SLC18A3 SLC1A2 SLC24A2 SLC25A23 SOWAHA SP9 SPEF1 SPOCK3 SYNDIG1L TAC1 TMEFF1 TMEM229A TMEM235 TSC22D4 TTYH1 Brain - Hypothalamus Female 50-59 Up ACHE AIRE ASIC2 B3GAT2 B4GAT1 BTBD17 C1QL1 CALB2 CALCR CALY CAMK2N2 CARTPT CENPVL2 CENPVL3 CNGB1 CTXN2 CXXC4 DBX2 DIRAS3 DLL3 DLX1 DNER DSCAM ECE2 ERAS FBLL1 FEZF1 FNDC9 FOXB1 GABRA3 GABRG3 GABRQ GFAP GRIK1 GRIN2D GRM7 GSX1 HAP1 HCRT HES5 HMX1 INPP5F INSM2 KCNIP1 KISS1R LHX5 LRRC55 LUZP2 LY6H MAGEL2 MC4R NAP1L3 NAP1L5 NGB NPSR1 NPVF OLIG1 OTP PABPC1L2A PABPC1L2B PCDH15 PCDH19 PHYHIPL PIRT PLPP4 PNMA5 PODXL2 PRDM12 PRDM13 RND2 RPE65 RTL1 RTP5 SCG2 SLC17A6 SLC22A17 SLC6A11 SMIM10L2B SMIM17 SMIM18 SNCG SOX1 SOX11 SYNGR3 TACR3 TCEAL7 TMEM114 TMEM196 TMEM255A TMIE TNR TRH TUBB3 VAT1L VGF VSTM5 VWC2L ZBTB8B ZCCHC12 ZDHHC22 Skin - Not Sun Exposed (Suprapubic) Female 50-59 Up AADACL2 ABCA12 ACVR2A ADGRF2 ADGRF4 AHNAK2 ANXA8L1 ARHGEF19 ATP6V1C2 BNIPL BPIFC C11ORF80 C3ORF52 CAPNS2 CASP14 CCL27 CDHR1 CLDN1 COL17A1 COL7A1 CTNNBIP1 CYP27C1 DEGS1 DLX5 DMKN DSC3 DSP EFNA3 ETV3 EXPH5 FAM83B GAL3ST4 GAN GATA3 GJB3 HOPX HR HS3ST6 IFFO2 IGFL2 IL20RA IL20RB IRF6 IRX3 KCNK7 KLC3 KLF4 KRT1 KRT14 KRT77 KRT80 KRTDAP LAMB4 LAMTOR4 LGALS7B LGALSL LIPK LIPM LRIT2 LY6G6C LYPD6B MFSD2A MYCL NECTIN4 NIPAL4 NKPD1 OVCH2 PERP PGLYRP4 PKP1 PLA2G4F POU2F3 PPP1R13L PPP1R14C RAPGEFL1 REEP4 RORA SDR42E1 SERPINB7 SLC10A6 SPTSSB STARD5 SYT8 TFAP2A TFAP2C TGM5 THEM5 TINCR TMEM45A TNFRSF18 TNFRSF19 TNS4 TP63 VANGL2 VAV3 WFDC5 WNT16 WNT3 XG ZNF273 Brain - Cortex Female 50-59 Up ABHD8 ADGRA1 ADGRB1 ADGRB2 AGBL4 ANKRD24 ATCAY BHLHA9 BRINP2 BRSK1 C2CD4C CABP1 CACNG3 CAMK1G CAMK2A CBLN2 CCK CHD5 CHRM1 CIT CLEC2L COL26A1 CREG2 CUX2 DAGLA DBNDD1 DGKZ DPF1 EIF4E1B ELFN2 FAIM2 FAM163B FAM81A FBXO41 FOXD4L6 FXYD7 GABBR2 GALNT8 GRIN1 HAPLN4 HECW1 HTR1A HTR3B ITPKA KCNAB2 KCNH3 KCNH5 KCNJ4 KCNN1 KCNS1 KCNS2 KCNV1 KIAA1549L KIF5A LCN15 LHX2 LINGO1 LRFN2 LYNX1 MAP1A MCF2L2 MCHR2 MGAT5B MPPED1 NANOS3 NCALD NEFL NLK NPM2 NRGN OLFM1 OPRD1 PACSIN1 PDE6H PHF24 PI4KA PLEKHM2 PRKAR1B PTPRT R3HDM1 RAB3A RAB6B RAPGEF4 RIMS3 RNF208 RORB RPH3A SHC3 SLC6A17 SNCB SNPH SNX32 SOHLH1 STX1A SYN1 TBR1 TESPA1 UNC5A VSTM2L ZDHHC22 Stomach Male 40-49 Up A4GNT ADA ADAM28 AGR2 AKR1B10 AKR7A3 AKR7L AMACR ANKRD22 ANXA10 ATP4A ATP4B B3GNT3 B4GALNT3 BAIAP2L1 BARX1 C9ORF152 CA2 CA9 CAPN13 CAPN8 CAPN9 CCKAR CCKBR CHIA CLDN18 CLIC6 COL2A1 CTSE CXCL17 CYP2S1 CYSTM1 DAZ1 DUOXA2 EPN3 ESRRG FER1L6 FMO5 FOXA2 FOXA3 FOXQ1 FRMD1 GALE GATA5 GBGT1 GCNT4 GHRL GKN1 GKN2 GPER1 GPRC5C KCNE2 KRTCAP3 LGALS9C LIPF MCIDAS MECOM MFSD4A MUC1 MUC5AC MUC6 MYH13 MYRF NBPF12 OSBPL7 PALM3 PDILT PGA3 PGA4 PGA5 PGC PIK3C2G PRR15L PSCA RASSF6 RFLNA RFX6 S100P SLC26A9 SLC4A2 SLC5A5 SLC9A2 SLC9A4 SMIM22 SULT1C2 TFF1 TFF2 TMED6 TMEM92 TOX3 TPCN2 TRIM50 TRIM73 TRIM74 VILL VSIG1 VSIG2 VWA2 XYLT2 ZFPM1 Colon - Sigmoid Male 40-49 Up ACTG2 ATP2B4 BAG2 BMP3 BTC C3ORF80 CAB39L CACNA1C CACNA1H CCDC69 CCL11 CDK8 CHRDL2 CHRM2 CNN1 COL24A1 CSRP1 EML1 FBXL22 FOXF1 FOXP2 FZD7 GALR2 GDNF GEM GJC1 GLB1L2 GLP2R GREM2 HAND1 HAND2 HLX HOXA13 HOXB3 HOXD10 HOXD11 HOXD12 HOXD13 ILK KCNH2 KCNQ4 KIZ KLHL23 LIMS2 LRCH2 LRIG1 LRRC3 MAB21L2 MASP1 MDM1 METTL24 MID1 MRGPRD MRGPRF MYL6 MYLK NKX2-3 NKX3-2 NPY4R NRP2 NT5DC3 NTSR1 NXN PDE3B PDE9A PDZRN3 PDZRN4 PGM5 PHOX2B PLA2G2C PLA2G4A PLEKHO1 PNCK PPP1R12B PTBP2 PTGFRN PTGS1 RAB23 RGS10 RNF150 ROR2 SAE1 SEMA3A SLMAP SMTN SPOP STON1 SYDE2 TACR2 TBC1D1 TEAD3 TES TGFB1I1 THAP8 TMEM252 TMTC2 TNFAIP8L1 TSPAN11 TSPAN2 VIP Cells - Cultured Fibroblasts Female 20-29 Up ABCE1 ABL2 ADAM9 ADAMTS6 ALDH1L2 ARSJ ASCC3 AZI2 BRIX1 C6ORF120 CALU CCBE1 CCNA2 CD109 CHAMP1 CKAP4 COA7 COL6A3 DCBLD2 DKK1 DSEL ECT2 EIF2AK4 EMC1 FBN1 FGF5 FKBP14 FOSL1 FRMD6 GNPNAT1 GPR176 GPX8 HOXC8 HS3ST3A1 HS3ST3B1 IGF2BP1 IGF2BP2 IGF2BP3 IKBIP IL13RA2 ITPRIPL2 KIF23 LMNB2 LOX LOXL2 LRP12 LRRC59 MME MSANTD3 NECTIN3 NIP7 NT5E PCDHGA11 PCDHGA12 PCDHGB4 PHAX PLOD3 PRIM2 PRKDC PRR16 PSAT1 PSG1 PSG5 PTRH2 PTX3 RCN1 RPF2 RRS1 SEC22B SLC1A5 SLC3A2 SLC7A11 SMG8 SNAI2 SNAPC1 SRGAP1 SRP72 STEAP1 STEAP1B TIGAR TMX3 TNFRSF10D TNPO1 TPBG TRAM2 TRIAP1 TRIB3 TRMT6 TRNP1 TRPA1 TWIST1 TWIST2 TXNRD1 UGGT1 ULBP1 VASN VGLL3 WNT5A XPOT ZNF281 Lung Female 20-29 Up ABCA3 ACOXL ACP5 ACVRL1 ADAMTS8 ADGRF5 AGER ALPP ANOS1 ATP11A CACNA2D2 CALCRL CASS4 CCL23 CD101 CEACAM6 COL6A5 CSF2 CSF3 CTSH CYP1A1 DKK2 DRAM1 EFCC1 EMP2 EPAS1 FCN3 FGFR4 FLRT3 FOLR1 FPR3 GGTLC1 GJA5 GPRC5A HHIP HTR3C ICAM1 IL1RL1 INMT KCNS3 KRT7 LAMP3 LBH LPCAT1 LRRN4 LTK MARCO MS4A15 MSLN NAPSA NDNF NFKBIA NKD2 NPC2 OR6N2 PALD1 PHEX PLEKHH2 PTPRB RAMP3 RBMS2 RGCC RHOBTB2 RIPPLY3 RNF145 ROS1 RS1 RSPO4 SCGB3A2 SDR16C5 SFTA2 SFTPA1 SFTPA2 SFTPB SFTPC SFTPD SLC34A2 SLC39A8 SLC6A14 SLC6A4 SLCO2A1 SLCO4C1 SLIT2 SMAD6 SNX30 SUSD2 TBC1D2 TBX2 TBX4 TCF21 TEK TFPI TMEM100 TMEM125 VEGFD VEPH1 VIPR1 WNT2 WNT3A XAGE2 Small Intestine - Terminal Ileum Female 20-29 Up ACSL5 ADAM28 ADAMDEC1 ADGRG7 AIM2 ALPI ANXA13 APOA4 APOBEC1 BANK1 BLK BMF BTNL3 C11ORF86 C17ORF78 CCL25 CCR6 CCR9 CD1C CD1D CEACAM18 CLDN15 CLDN2 CR2 CTLA4 CXCR5 DEFA5 DEFA6 DERL3 DGAT1 DMBT1 ESPNL FABP2 FABP6 FAM177B FCMR FCRL1 FCRL2 FCRL3 FCRL4 FOXP3 GPR171 GPR82 HKDC1 HLA-DOB HNF4G ICOS IL24 IL2RA IL7R IRF8 ITLN2 KCNJ13 KLHL6 LRRC66 MADCAM1 MALRD1 MMP12 MOGAT3 MS4A10 MTTP MUC3A MYO1A MYRFL NLRC3 NLRP6 OLFM4 P2RX5 PARP15 PLA2G2D PLCB3 RBP2 REG4 RETNLB SCML4 SI SIRPG SLC10A2 SLC25A53 SLC28A2 SLC5A9 SLC6A19 SLFN14 SOAT2 SPINK4 TIFAB TIGIT TM4SF20 TM6SF2 TMEM253 TRPM5 TTC24 TXK UGT1A5 VIL1 VPREB3 ZNF101 ZNF107 ZNF80 ZNF831 Nerve - Tibial Female 20-29 Up AATK ACKR2 ADAMTS14 ADGRG2 ANGPTL7 APOD ARHGAP19 ARHGEF10 BIRC7 BMP8B BNC2 CASKIN2 CDH19 CDH7 CLCN2 CLDN19 CLDN20 CNTF COL28A1 DACT1 DCLK3 DHH DKK2 DRP2 EBF2 EGFL8 EMILIN3 ENPP6 EPB41L2 EXTL1 FGFBP2 FLNB FOXD1 FOXD2 FOXD3 GAS2L3 GJC3 GLI1 HSPA12A IGFBP6 IL17B IL9 INF2 ITGA6 KANK4 KCNK12 KIF19 KLRG2 LCTL LGI2 LGI4 MAPK8IP1 MATN3 MEOX2 MFAP5 MIA MLIP MPZ NCMAP NEK1 NGFR NRIP2 OR2AT4 OR6B2 OR6B3 OTUD7B PAPLN PDGFRL PLEKHA4 PLEKHG7 PMP22 PODN PRICKLE1 PROS1 PROSER2 PRRG3 PRX PTPDC1 PTPRU SBSPON SECISBP2L SEMA3B SEMA4C SEMA5A SFRP5 SH3TC2 SHC4 SLC22A3 SLC25A48 SLC2A1 SMCO3 SORCS2 SPTBN5 TJP1 TMEM215 TMPRSS5 USP53 VIT WNT6 ZDHHC8 Pancreas Female 30-39 Up AKR7A3 AMY1A AMY1B AMY2A AMY2B ANXA4 AQP12A AQP12B AQP8 ARL5C BHLHA15 CATSPERB CEACAM16 CEL CELA2A CELA3A CELA3B CFTR CLDN10 CLDN2 CLPS CLPSL1 CLPSL2 CPA1 CPA2 CPB1 CTRB1 CTRB2 CTRC CTRL CUZD1 EPB41L4B ERICH5 ERO1B ERP27 FAM3B FBXW12 FKBP11 G6PC2 GATM GCG GLP1R GNMT GP2 GPHA2 GPR150 GUCA1C IAPP IL22RA1 INS KCNK16 KCTD14 KIRREL2 KLK1 LGALS2 LHFPL5 MNX1 NR5A2 OR10G4 OR10G7 P4HB PDIA2 PDX1 PGGHG PLA2G1B PLPP5 PNLIP PNLIPRP1 PNLIPRP2 PRDX4 PRSS1 PRSS2 PRSS3 PTF1A RBPJL REG1A REG1B REG3G RNF186 RRBP1 SCTR SEL1L SERPINI2 SLC16A12 SLC30A2 SLC30A8 SLC38A5 SLC39A5 SLC43A1 SLC4A4 SPINK1 SYCN TC2N TECPR1 TMED6 TMEM52 TPST2 XBP1 ZNF710 ZNF98 Adrenal Gland Female 30-39 Up AADAC ABCB1 ABCF3 ADGRV1 AKAP7 AKR1B1 ALAD ALAS1 AMHR2 AOX1 AQP11 AS3MT ASB4 C2CD2 C8ORF33 CCDC134 CELA1 CERS2 CLRN1 CREBL2 CTSA CYB561A3 CYB5B CYP11A1 CYP11B1 CYP17A1 CYP21A2 CYSLTR2 DDB1 DEXI DHCR24 EBP EPHX1 FADS2 FDX1 FDXR GALM GNPTG GNS GSTA1 GSTA3 GSTA4 GSTA5 HDHD3 HSD3B2 IDH1 INHA KCNJ5 KCNK3 KCNN2 KCNQ1 KLHL4 LONP1 LRRC61 MAP3K15 MAP3K5 MC2R MGARP MRAP NR0B1 NR5A1 PAPSS2 PCCB PEBP1 PEG10 PEX3 PLBD2 PLEK2 PORCN PRDX3 PRLR QPCT QPRT RARRES2 RDX RGN RMDN2 RNF128 SCARB1 SERPINA5 SLC16A9 SLC37A2 SLC40A1 SLC47A1 SLC8B1 SNTB1 SOAT1 SPTSSA SREBF1 STAR SULT2A1 TBC1D8B TKFC TM7SF2 TMEM150C TPD52L1 TSPAN12 VEPH1 ZNF275 ZNF280A Artery - Coronary Female 30-39 Up ART4 C7 CCDC3 FMOD FPR3 GPR34 HAPLN1 HEYL HS3ST2 ID3 INMT LGI2 LGR6 LRRC17 MSC PTGIS RGS7BP SLAMF8 TIMP1 WNT9B Heart - Left Ventricle Female 30-39 Up ACTC1 B3GALT2 BSG BZW2 CASQ2 CCDC141 CDH2 CKMT2 COQ10A COQ3 COQ9 COX5A COX7B CPT1B DAND5 DDO DECR1 DLAT DLD EIF1B ETFDH FABP3 FBXO40 FGF12 FHL2 FHOD3 FITM2 GJA3 GOT1 HADHB HRC HSDL2 HSPB3 HSPB7 KLHL31 KLHL7 LAPTM4B LDHB LRRC10 LSMEM2 MDH1 MLYCD MPC1 MRPS36 MTUS2 MYBPC3 MYH7 MYH7B MYL2 MYL3 MYLK3 MYOM2 MYOZ2 MYZAP NDUFA1 NDUFA6 NDUFAB1 NDUFB3 NDUFS1 NEBL NKX2-5 NNT OGDH OXCT1 PDE1C PDHA1 PKP2 PLCXD3 PLN POPDC2 PPM1K PPP1R1C PTDSS1 RBM20 RD3L RNF207 RYR2 SCN5A SDHA SGCG SH3RF2 SLC25A30 SLC25A4 SLC41A1 SLC4A3 SLC8A1 SMCO1 SMPX SMYD2 TECRL TENM2 TIMM8B TMEM182 TNNI3 TNNI3K TNNT2 TPM1 UQCRC1 UQCRC2 UQCRH Stomach Female 30-39 Up ADAM28 ADH1C AGR2 AKR1B10 AKR7A3 AKR7L ALDH1A1 ANXA10 ARSD ATP4A ATP4B B4GALNT3 C9ORF152 CA2 CA9 CAPN8 CAPN9 CCKAR CCKBR CHGA CLDN18 CLIC6 COL2A1 CTSE CXCL17 CYP2S1 CYSTM1 DGKD EPN3 ERN2 ESRRG FER1L6 FMO5 FOXA2 FOXA3 FOXQ1 FRMD1 GALE GATA5 GCNT4 GHRL GKN1 GKN2 GPRC5C INSRR KCNE2 KRTCAP3 LGALS9B LHX5 LIPF MCIDAS MECOM MFSD4A MUC1 MUC5AC MUC6 MYH13 NQO1 OR10R2 OSBPL7 PALM3 PDILT PGA3 PGA4 PGA5 PGC PIK3C2G POU5F1 PSCA PTGDR2 PXMP2 REP15 RFLNA RFX6 S100P SIDT2 SLC26A9 SLC38A11 SLC4A2 SLC5A5 SLC9A2 SLC9A4 SMIM22 SST STARD10 SULT1C2 TFF1 TFF2 TMEM92 TPCN2 TRIM50 TRIM73 TRIM74 UGT1A6 VILL VSIG1 VSIG2 VWA2 XYLT2 ZFPM1 Small Intestine - Terminal Ileum Female 30-39 Up ADAM28 ADGRG7 AKR7L ALPI AMN ANXA13 APOA4 APOBEC1 BAIAP2L2 BANK1 BLK BMF BTNL2 BTNL3 C17ORF78 CACNA1F CCL25 CCR9 CD19 CD1D CDHR2 CDHR5 CEACAM18 CEACAM20 CES2 CLDN15 CPO CTLA4 CXCR5 DEFA5 DEFA6 DGAT1 DNASE1 DPEP1 ENPEP FABP2 FABP6 FAM151A FAM177B FCRL1 FCRL2 FCRL4 GBA3 GPR152 GUCA2B GUCY2C HKDC1 HNF4G KCNJ13 MALRD1 MEP1A MEP1B MS4A10 MS4A8 MUC17 MUC3A MYO1A MYO7B MYRFL NAALADL1 NLRC3 NLRP6 OAT OPN1MW3 P2RX5 PARP15 PLCB3 PRAP1 RBP2 REG4 SCML4 SI SLC10A2 SLC13A2 SLC15A1 SLC17A8 SLC23A1 SLC28A2 SLC39A4 SLC51B SLC5A1 SLC5A9 SLC6A19 SLC7A9 SMIM24 SOAT2 TM4SF20 TM6SF2 TMEM253 TNFRSF13C TNFSF15 TREH TRPM5 TTC24 UGT2A3 VIL1 VPREB3 XPNPEP2 ZNF107 ZNF831 Artery - Coronary Male 40-49 Up AEBP1 ANTXR1 ARL4AP5 ASPN BGN C1ORF54 C1QTNF1 C1QTNF2 CCDC3 CCL19 CD151 CDH13 CFH CMKLR1 COL18A1 CPXM2 CRIP1 ECM2 EDIL3 EFEMP1 FBLIM1 FMOD FOXS1 FPR3 GJA5 GLIS2 GPR34 HAPLN1 HAPLN3 HEYL ID4 IGFBP2 IGFBP7 ITGB5 IZUMO1R KCNA5 KCNK15 KCNT2 LGR6 LRRC17 LTBP1 LTBP2 MAP3K7CL MFAP4 MFGE8 MGP MMP23B MSC MSR1 MTHFD1L MYO1D NDUFA4L2 NTF3 OGN OLFML2B OMD P4HA3 PDGFA PLA2G5 PPP1R14A PRDM16 PRKG1 PTGIS RASL11A SCARF2 SLAMF8 SPINK13 ST6GAL2 SUGCT SULF1 TBX18 TBX2 TBXA2R TGM2 THBS2 TIMP1 TNFAIP8L3 TNFRSF11B TNFSF12 TRABD2B VCAN VMO1 WFDC1 Liver Male 40-49 Up A1BG A1CF ABCC6 ABCG8 ACSM2A ACSM2B AGXT AKR1C4 ALDH8A1 AMBP AMDHD1 ANG ANGPTL3 APCS APOB APOF APOH ASGR1 ASGR2 ASL BAAT C4BPA C5 C6 C8A C8B C8G C9 CA5A CCL16 CFB CFHR2 CFHR5 CPB2 CPN2 CPS1 CYP2D6 CYP2E1 CYP8B1 F11 F12 F13B F2 F7 F9 FGB FGL1 GC GDF2 GYS2 HABP2 HAO1 HAO2 HGD HP HPN HPX IGFALS INHBC INS-IGF2 ITIH1 ITIH2 ITIH3 ITIH4 KMO KNG1 LIPC MASP2 MAT1A MBL2 MST1 NR1I3 ORM1 ORM2 PIPOX PLG PLGLB2 PON1 PON3 PROC PROZ SAA4 SARDH SDS SERPINA1 SERPINA6 SERPINA7 SERPINC1 SERPINF2 SLC22A1 SLC22A9 SLC27A2 SLC27A5 SLC38A4 SLCO1B1 TAT TDO2 TFR2 TTPA VTN Small Intestine - Terminal Ileum Male 40-49 Up ACE ACE2 ACSL5 ADGRG7 ALPI AMN ANKS4B ANPEP ANXA13 AOC1 APOA4 APOBEC1 BAIAP2L2 BTNL3 C11ORF86 C17ORF78 CCL25 CCR9 CDHR2 CDHR5 CEACAM18 CEACAM20 CHST5 CLDN15 CPO DEFA5 DEFA6 DGAT1 DHRS11 DMBT1 DPEP1 ENPEP EPS8L3 ERICH4 FABP2 FABP6 FAM151A FAM177B FCRL2 GBA3 GUCA2A GUCA2B HKDC1 HNF4G IL2 ITLN2 KCNJ13 MADCAM1 MALRD1 MEP1A MEP1B MISP MOGAT3 MS4A10 MS4A8 MTTP MUC17 MUC2 MUC3A MYO1A MYO7B MYRFL NAALADL1 NLRP6 PEPD PLCB3 PRAP1 RBP2 REG4 SCML4 SI SLC10A2 SLC13A1 SLC13A2 SLC15A1 SLC17A8 SLC23A1 SLC23A3 SLC28A2 SLC51B SLC5A1 SLC5A9 SLC6A19 SLC6A20 SLC7A9 SMIM24 SPINK4 SULT1C3 TBX10 TM4SF20 TM6SF2 TMEM150B TMEM253 TMIGD1 TREH TUBAL3 UGT1A5 VIL1 VPREB3 XPNPEP2 Pancreas Female 20-29 Up AMY1A AMY1B AMY1C AMY2A AMY2B AQP12A AQP12B AQP8 ARL5C BHLHA15 CEACAM16 CEL CELA2A CELA2B CELA3A CELA3B CFTR CLDN10 CLPS CLPSL2 CPA1 CPA2 CPB1 CTRB1 CTRB2 CTRC CTRL CUZD1 EPB41L4B ERICH5 ERO1B ERP27 FAM3B FBXW12 FKBP11 G6PC2 GATM GCG GLP1R GNMT GP2 GPHA2 GPR119 GRPR GUCA1C HOMER2 IAPP IL22RA1 INS KCNK16 KIRREL2 KLK1 LENG9 LGALS2 LHFPL5 MNX1 NPHS1 NR5A2 ONECUT1 OR10G4 OR4D5 OR6M1 OR8D4 P4HB PDCD4 PDIA2 PDX1 PGGHG PKHD1 PLA2G1B PNLIP PNLIPRP1 PNLIPRP2 PRDX4 PRSS1 PRSS2 PRSS3 PTF1A RBPJL REG1A REG1B RRBP1 SCTR SEL1L SERPINA4 SERPINI2 SLC16A12 SLC30A2 SLC30A8 SLC38A5 SLC39A5 SLC43A1 SLC4A4 SPINK1 SPSB4 SYCN TECPR1 TMED6 TPST2 TRPV6 Brain - Spinal Cord (Cervical C-1) Female 40-49 Up ABCA2 AGPAT4 ANKRD40 ANLN APLP1 ARRDC4 BACE1 BCAS1 C10ORF90 CA14 CARNS1 CDK18 CHADL CHRM5 CLDN11 CLDND1 CMTM5 CNDP1 CNP CNTN2 CNTNAP4 CTNNA3 DBNDD2 DPYSL5 DTNB DTX4 DYNC1LI2 ENPP6 ERMN FA2H FEZ1 FGFR2 FMNL2 FNTB GAL3ST1 GFAP GJC2 GMFB GPR37 GPR62 HAPLN2 HMSD HOXB8 HOXD1 KLK6 LHPP LLGL1 LRRC63 MAG MAP4 MAP6D1 MAP7 MARCKSL1 MBP MOBP MOG MTMR10 MTURN MVB12B MYRF NIPA1 NKAIN2 NKX2-2 NKX6-2 OR9A2 PACS2 PAQR4 PAQR6 PAQR8 PCSK6 PEA15 PEX5L PKP4 PLEKHB1 PLP1 PRRG1 RAPGEF5 RASSF2 RBM11 S100B SAP18 SEMA4D SIRT2 SLAIN1 SLC44A1 SLC5A11 ST18 STMN4 SYNJ2 TBC1D12 TMEM144 TMEM151A TMEM88B TP53INP2 TRAK2 TRIM41 TUBA1A UGT8 ZFP57 ZNF488 Brain - Hypothalamus Male 70-79 Up ACHE ADCYAP1 AGRP AIRE AVP B3GAT2 B4GAT1 BSX CALB2 CALCB CALCR CALY CAMK2N2 CARTPT CENPVL2 CFC1 CNGB1 CRH CRYGA CXXC4 DIRAS3 DLX1 DSCAM ECE2 ECEL1 ERAS FBLL1 FEZF1 FNDC10 FNDC9 FOXB1 GABRG3 GABRQ GHRH GNG4 GNG8 GRIK1 GRIN2D GRM7 GSX1 HAP1 HCRT HCRTR2 HMX1 INPP5F KCNG4 KCNIP1 KISS1R LHX5 LUZP2 LY6H MAGED4 MAGEL2 NAP1L5 NGB OTP PABPC1L2A PABPC1L2B PCDH11Y PCDH19 PCSK1 PLPP4 PMCH PNMA5 PODXL2 PPP1R17 PRDM12 PRDM13 R3HDML RHBDD2 RND2 RTL1 RTP5 SCG2 SGSM1 SLC17A6 SLC6A11 SMIM10L2B SMIM18 SNCG SOX1 SOX11 SOX3 SST SYNGR3 SYT6 TACR3 TMEM114 TMEM17 TMEM255A TMIE TRH TUBB3 UCHL1 VAT1L VGF VSTM5 VWC2L ZBTB8B ZCCHC12 Skin - Sun Exposed (Lower Leg) Male 70-79 Up AADACL2 ABCA12 ABHD12B ACER1 ADGRF2 ADGRF4 ALOX12B ALOXE3 ANKRD35 ATP6V1C2 BPIFC BTBD16 C1ORF68 C3ORF52 CARD14 CASP14 CCL27 CDHR1 CENPP CLEC2A COL17A1 CTNNBIP1 CYP4F22 DEGS1 DLX5 DMKN DSC1 DSG1 DSP EFNA3 EGLN3 ELOVL4 EXPH5 FAM83B FLG FLG2 GJB4 HOPX IDE IGFL2 IGFL3 IL25 IL36B IL36G IL36RN KLC3 KLK14 KLRF2 KRT1 KRT10 KRT77 KRT80 KRTDAP LAMB4 LCE5A LGALSL LIPK LIPM LY6G6C NECTIN4 NIPAL4 NLRP10 OR10A6 OR5P2 PERP PGLYRP4 PKP1 PLA2G3 PLA2G4E PNPLA1 POF1B POU2F3 PPP1R13L PSAPL1 RDH12 RDH13 SBSN SDR42E1 SDR9C7 SERPINA12 SERPINB7 SLC10A6 SLC39A2 SLC52A1 SP5 SPRR2G SPTSSB SRY SYT8 TFAP2A TGM5 THEM5 TINCR TMEM45A TUFT1 UNC93A WFDC12 WFDC5 WNT3 ZNF750 Adipose - Subcutaneous Male 70-79 Up ABCD2 ABHD15 ACKR1 ACO1 ACVR1C ADAMTS5 ADCY4 ADGRL4 ADH1B ADIPOQ ADM5 ADRA2A AFAP1L1 AGPAT2 AGTR1 AIFM2 ALG9 ANGPT4 ANGPTL2 ANGPTL4 APOL3 APOL6 AQP7 ARHGEF15 BMP6 C19ORF12 CD248 CD36 CFD CIDEA CIDEC CLDN5 COX14 CPM CYGB DOCK11 EBF1 EBF3 ELMOD3 FABP4 FAM124B FAM89A FGD5 FZD4 G0S2 GALNT15 GFRAL GHR GPD1 GPR146 HEBP2 INHBB ITGB1BP1 ITIH5 KCTD12 KRTAP13-4 LHX6 LIMA1 LIPE LPL LRRC32 LRRN4CL LVRN MMRN2 MOCS1 NMT2 NR1H3 NXNL1 OPN1MW3 PALMD PECAM1 PEX19 PHLDB1 PLIN1 PLIN4 PNPLA2 PPARG PPP1R1A PTGES RAMP2 RBM3 RDH5 RNF125 SEMA3G SLC19A3 SMIM3 SPRY1 SRPX2 STAT5A STEAP4 SYNE3 TACR1 TBC1D16 TIMP3 TMEM132C VEGFB VKORC1L1 VWF ZBED3 ZNF366 Thyroid Male 70-79 Up ABCA13 ABHD11 ADM2 AFAP1L2 AMELY ARHGAP8 ATP13A4 BMP8A C16ORF89 CCL21 COL23A1 COL4A3 CRABP1 CRYGN CYTH2 DAPK2 DUOX2 EFCAB13 EPOR EXOC3L2 FGFRL1 FLT4 FOXE1 FREM2 FSCN2 GLCCI1 GOLGA8A GOLGA8B GOLGA8R GRK1 HEMK1 HHEX HIRA HOOK3 IFT140 IL15 INPP5J IVD IYD KATNAL2 KCNC3 KCNJ16 KLHL14 LCN12 LIPG LRP2 LRRC75B MPPED2 MROH1 MSANTD2 MT1F NEK8 NKX2-1 OR2A1 PABPC1L PAX8 PBX4 PCED1A PDE8B PKHD1L1 PKNOX1 PLA2G6 PLA2R1 PLEKHH1 PPP1R13B PRTG RASSF4 RCBTB1 RECQL5 RGL3 RHPN1 RTN4RL2 SALL4 SCX SH3D21 SHISA2 SLC12A8 SLC16A11 SLC25A29 SLC26A4 SLC26A7 SLC4A5 SLC5A8 TBL1Y TCERG1L TFF3 TG TLE6 TMEM234 TMEM243 TSHR UTS2R WDR72 WDR86 ZBED2 ZMAT1 ZNF114 ZNF486 ZNF804B ZNF90 Brain - Spinal Cord (Cervical C-1) Male 70-79 Up ABCA2 AGPAT4 ANLN APLP1 BACE1 BCAS1 C21ORF91 CA14 CARNS1 CCNE2 CDK18 CHADL CHRM5 CLDND1 CMTM5 CNP CNTN2 CNTNAP4 CTNNA3 DBNDD2 DPYSL5 DTNB ELOVL2 ENPP6 ERMN EVI2A FA2H FEZ1 FGFR2 FMNL2 FNTB GAL3ST1 GFAP GJC2 GPM6B GPR151 GPR37 GPR62 HAPLN2 HMSD HOXD1 KCNJ10 KLK6 LANCL1 LHPP LLGL1 LRRC63 MAG MAP7 MARCKSL1 MBP MOB3B MOBP MOG MTMR10 MTURN MVB12B MYRF NIPA1 NKAIN2 NKX2-2 NKX6-2 OR9A2 PACS2 PAQR4 PAQR6 PAQR8 PCSK6 PEA15 PEX5L PIP4K2A PKP4 PLEKHB1 PLP1 PRRG1 QKI RAPGEF5 RASSF2 RBM11 RNF13 S100B SEMA4D SIRT2 SLAIN1 SLC44A1 SLC5A11 SNX24 ST18 STMN4 SYNJ2 TBC1D12 TMEM144 TMEM151A TMEM88B TNFRSF21 TP53INP2 TRAK2 TUBA1A UGT8 ZNF488 Artery - Tibial Male 70-79 Up ACAN ACTA2 ACTN4 ADAMTS1 ADARB1 ADIRF AEBP1 ARHGAP1 ARHGEF10L ARHGEF17 ARHGEF39 ATL3 AVPR1A BCOR C11ORF96 C1ORF54 C1QTNF1 CA5B CCDC3 CFH CHSY3 CMKLR1 COL14A1 COL18A1 COMP CPED1 CRIP1 CRLF1 CRTAC1 CSPG4 CSRP2 DACT3 DSTN ELL2 ETV6 FHL5 FMOD FOXC1 FOXC2 FOXL1 FRZB GPC6 HAPLN3 HAUS7 HES4 HEY2 HEYL HTR1B ID2 IGFBP7 ITGA5 JAG1 JAK2 KBTBD13 KCTD10 LDLRAD2 MAP7D3 MCAM MYH9 MYO1D NDUFA4L2 NOTCH3 NTF3 NTRK3 OR51C1P P2RX1 PCDHB16 PDGFA PDGFRB PGF PLEKHG3 PLS3 PPP1R3C PRDM16 PRELP PRSS23 RASL12 RERGL RHBDF1 RHOB RNF180 SCARF2 SDK1 SFRP2 SH3RF3 SIVA1 SMAD7 SMIM10 SOST SPEG SULF1 TASP1 TBX18 TBX2 TINAGL1 TNC TRABD2B WTIP ZFHX3 ZNF395 Breast - Mammary Tissue Male 70-79 Up ACKR1 ADAMTS3 ADCY4 ADGRL4 ADM5 ADRB2 AGTR1 ANGPT4 APOL3 AREG ARHGEF15 AVPR2 BMP6 BTNL9 C2CD4B CCL14 CCRL2 CD300LG CD36 CDH5 CFD CLDN5 CLEC14A CLEC1A CYGB CYYR1 DKK4 DLL4 DMRT2 DUSP23 ECSCR EGFL7 EGFLAM EMCN FABP4 FAM110D FAM124B FAM162B FGF10 GFRAL GIMAP5 GJA4 GLRA3 GNG11 GPIHBP1 GPR146 GSC HOXB7 HOXD8 HSPA12B ICAM2 ITM2A JUN JUND KANK3 KLF2 LDB2 MEOX1 MMRN2 MYCT1 NEDD9 NOSTRIN NPFFR2 NR1H3 PAPPA2 PDGFRL PECAM1 PKD1L2 PLAC9 PLEKHG1 PLIN2 PML POLE4 RAMP2 RAPGEF3 RASIP1 RBP7 ROBO4 S1PR1 SCGB1D2 SCGB2A2 SELP SERPINF1 SNTG2 SOCS2 SOX17 SPAAR SPRY1 STEAP4 TACR1 TCN2 TIE1 TIMP4 TNN TWIST1 USHBP1 VAMP5 VWF WNT11 ZNF792 Lung Male 70-79 Up A2M ACKR1 ACP5 ACVRL1 ADAMTS8 ADGRF5 ADGRL2 AGER ARSI BCL6B BMP5 BMPR2 C20ORF202 CALCRL CASS4 CCDC102B CCL18 CCL23 CD4 CDH5 CLEC1A COL6A6 COX4I2 DOCK6 EGFL6 EMP2 EPAS1 FCN3 FGFR4 FOLR1 GALNT18 GBP4 GIMAP8 GPC3 GPER1 GPRC5A GPRIN3 HGF HLA-DRB5 HTR3C ICAM1 IDO1 IER5 IL15RA IL18BP IL1RL1 IL7R INMT IRAK2 ITGA2 KANK3 LRRC32 LRRN4 LTK MARCO MSR1 NDNF NKD2 OLR1 PALD1 PARP14 PCDH12 PCDH17 PECAM1 PHEX PIEZO2 PLA1A PTGIR PTPRB RAMP3 RBMS2 RGCC RSPO4 SAT1 SFTA2 SHROOM4 SLC6A4 SLCO2A1 SLCO4A1 SMAD6 SOSTDC1 SPON1 STARD8 TBX2 TBX4 TCF21 TEK TFEC TFPI TIMP1 TMEM100 TMEM255B TMEM74B TNFAIP2 TNFRSF6B TNFSF10 VHLL VIPR1 WNT2 WNT3A Heart - Atrial Appendage Male 70-79 Up ACTC1 ADAMTS7 ADAMTSL2 ALPK2 ANKRD1 ASPG BCO2 BMP10 C14ORF180 CASQ2 CCDC141 CFH CHRNE CIB2 CORIN CPNE5 CRIP2 CSRP3 CYP2J2 DAND5 DHRS7C DKK3 DOK7 EIF1AY EIF1B ENG FABP3 FBLN2 FGF12 FGF23 GATA4 GLP1R GSG1L GSN GXYLT2 HCN4 HHATL HRC HSPB2 HSPB3 HTRA3 IGSF5 ITGB1BP2 KRBA1 LAPTM4B LRRC10 MYBPC3 MYBPHL MYH6 MYL4 MYL7 MYLK3 MYOZ2 MYZAP NDUFAB1 NEBL NES NKX2-5 NMRK2 NPPA NPPB NRTN OR10P1 OTOGL PABPC4L PAM PCOLCE2 PLA2G5 POPDC2 PRKAG2 PRR32 PXDNL RABGAP1L RBM20 RBPMS2 RD3L RILPL1 RNF207 RYR2 SBK2 SBK3 SCN5A SHD SLC25A4 SLC4A3 SLC8A1 STAT4 SYNPO2L TBX20 TBX5 TECRL TMEM182 TNNI3 TNNI3K TNNT2 TPM1 TRIM55 UQCRB VASH1 WNK2 Heart - Left Ventricle Male 70-79 Up ASB18 C14ORF180 CSRP3 FABP3 HSPB3 HSPB7 MYBPC3 MYH7B MYL3 NKX2-5 NMRK2 OR4C45 POPDC2 SCN5A TCF15 TLL2 TNNI3 TNNT2 XIRP1 Esophagus - Gastroesophageal Junction Male 70-79 Up A4GALT ABL1 ADAM33 ADAMTSL4 ANKS1A C1QTNF3 CACNB2 CBY1 CDHR3 CDPF1 CNGA3 COL4A5 COL4A6 COL6A1 CUEDC1 DBN1 DEFB124 DENND2A DHX35 DMPK DPT EFCC1 EML1 F2RL2 FAM89B FGL2 FOXF1 FOXF2 FOXP1 GLP2R HIF3A HOXA2 HOXA3 HOXA4 HOXB2 HOXB3 HOXB4 HS1BP3 HSF4 HTRA3 IGF1 IGHMBP2 ISL2 JPH2 KCNQ4 KIAA0753 LIMS2 LRRN4CL LTBP4 LZTS2 MAMDC2 MANBAL MARVELD1 MEIS1 MPZL1 MRGPRF MYL6 MYOC NFASC NFIA NKX6-1 NME4 NPFF NPIPB13 NTRK1 P2RX2 PDLIM7 PHF19 PID1 PLEKHO1 PLXDC1 PPP1R12C RBPMS REM1 RGMB ROR2 RSPO3 SCARA5 SELENOM SERPINE2 SHISA3 SLC1A7 SLC29A1 SMTN SNAPC2 SSC5D STARD9 STON1-GTF2A1L SUPT20HL1 SYNM TGFB1I1 THBS3 TNFSF12 TNXB TPCN2 TPSD1 TRIM47 TRMT61A ZNF232 ZNF511 Stomach Male 70-79 Up ATP4B BARX1 C2CD4B CA9 CAPN6 CCKAR CCKBR CHAC1 CHGA CHIA CLIC6 GHRL GRP ISL1 KCNE2 LIPF MUC1 MUC6 NBPF12 NPPC OR2AG1 OR52L1 OR5I1 PDILT PGA3 PGA4 PGA5 PGC RFX6 SST TAAR1 TPH1 XYLT2 Testis Male 70-79 Up ACTL8 ADAM7 ANHX ANKRD18A ASB9 C7ORF33 CBX2 CCDC150 CCDC38 CGB1 CLEC12B COX7B2 COX8C CST9L CT45A10 DCAF8L2 DEFB119 DEFB123 DNAJB7 DPPA2 DPPA4 EPPIN ESPN FAM236A FAM236D FATE1 FNDC7 FOXN4 FOXR1 GBX1 GDPD4 GLIPR1L1 GLUD2 GOLGA6L22 GOLGA8F GPX6 HES3 HMGN5 IGLL1 IL21 INHA ISYNA1 KCNK13 KEL KRBOX1 KRTAP20-4 LCNL1 LUZP4 MAGEA1 MAGEA11 MAGEA4 MAGEB4 MEIKIN MRGPRG MS4A13 NANOGNB NKX2-8 NXF3 NYX OR1C1 OR1R1P OR2F2 OR2V2 OR7A10 OVOL3 PAGE1 PAGE2B PAGE5 PASD1 POTEA PRAME PRDM7 PRND PRSS38 PRSS41 PRY RFPL3 RHOXF2B SAGE1 SLC52A3 SLC9C2 SPATA45 SSX3 TAF7L TBX22 TCL1B TEX43 TPRX1 TSPY10 TSPY2 TSPY4 UTF1 VCX2 VN1R2 WFDC3 WFDC6 WNK3 XAGE5 ZNF560 ZNF705G Brain - Frontal Cortex (BA9) Male 40-49 Up AGBL4 AK5 ATRNL1 BHLHA9 C11ORF87 C1ORF216 C1QL3 C3ORF80 CABP1 CBLN2 CCK CHN1 CLEC2L CNTNAP2 COL26A1 CREG2 CTXN3 DLGAP1 DPP10 EIF4E1B ELAVL4 ENC1 EPHX4 ERC2 FAM163B FAM81A FREM3 FRMPD4 FXYD7 GABBR2 GABRA1 GABRG2 GALNT8 GAP43 GLRB GRIA3 GRIN2A HCN1 HECW1 HTR2A HTR3B KCNC2 KCNH5 KCNS1 KCNS2 KCNV1 KCTD16 KIAA1549L LMO4 LRFN5 MAPK10 MCHR2 MPPED1 NAP1L2 NAPB NCALD NEFL NEFM NELL1 NELL2 NLK OLFM1 OLFM3 OR14I1 PDE6H PGM2L1 PHF24 PNMA2 PNMA6A POU6F2 PRKAR1B PROKR2 PTPRT R3HDM1 RAB6B RGS4 RIMS3 RORB RPH3A RTN1 RTN3 RXFP1 SERPINI1 SGTB SLC4A10 SLITRK1 STX1A SULT4A1 SYN2 SYP SYT1 SYT13 TBR1 TESPA1 TMEM132D VSNL1 VSTM2A YWHAH ZDHHC22 ZNF365 Brain - Cerebellar Hemisphere Male 40-49 Up ADAM22 AKAIN1 ALS2 ATP6V1G2 BARHL1 BARHL2 CA10 CACNA1A CADPS2 CALN1 CAMK4 CAMKK2 CBLN1 CBLN3 CCDC175 CDH22 CHD7 CHN2 CLK4 CLVS2 CNPY1 COL27A1 CPLX4 CRTAM DIRAS2 DISP2 EN2 EPB41 ETV1 FGF9 FSTL5 GABRA6 GABRD GLCE GPR137C GRIK2 GRM1 GRM4 KCNA1 KCNC1 KCND2 KCNJ3 KCNK9 LHX1 MAB21L1 MDGA1 MEGF11 MMP24 MTCL1 MYT1 NBPF20 NEUROD1 NEUROD2 NKX6-3 NPTX1 NREP NRXN3 PAK5 PAX6 PCDHA8 PCDHGC4 PKIB POLB PPFIA4 PRR35 PSD3 RAB3IP RELN RUNX1T1 SCN2A SH3GL2 SHF SHISA8 SLC35F4 SLC8A2 SOGA1 SRGAP2B SRRM3 SRRM4 STXBP5L SYT2 SYT4 TFAP2E TIAM1 TMC2 TMEM145 TMEM178A TMEM266 TNFRSF25 TRIM67 UNCX VSX1 ZBTB18 ZIC1 ZIC2 ZIC3 ZIC4 ZIC5 ZNF382 ZNF521 Brain - Substantia Nigra Male 40-49 Up ABCA2 ADARB2 ANKRD40 ASPA BCAS1 CA14 CARNS1 CDK18 CHADL CHST6 CLDND1 CLEC19A CLEC9A CMTM5 CNDP1 CNP CNTN2 CNTNAP4 COL9A2 CTNNA3 DBNDD2 DBX2 DOHH DYNC1LI2 ERMN EVI2A FEZ1 FGF1 FOXB1 GCSH GPR37 GPR62 GPRC5B HAPLN2 HIPK2 HMX1 ITPKB KCNE5 KCNG4 KIF6 KLHL32 KLRC2 KLRC3 LHPP LLGL1 LPAR1 LUZP2 MAG MARCKSL1 MBP MKRN3 MOBP MOG MTURN NIPA1 NIPAL3 NKAIN2 NKX6-2 NTS NTSR2 OLIG1 OR2L13 P2RY12 PAIP2B PAQR6 PDE6B PIP4K2A PIRT PKP4 PLEKHB1 PLP1 PRR18 PRRG1 QDPR RGS8 RND2 RNF141 ROM1 RPE65 S100B SCRG1 SEC14L5 SHTN1 SLAIN1 SLC5A11 SLC6A11 SLCO1A2 SPOCK3 SPX SYNJ2 TMEM144 TMEM235 TMEM88B TP53INP2 TRIL TRIM41 TSC22D4 TTYH2 ZFP57 ZNF488 Brain - Amygdala Male 40-49 Up AK5 AMZ1 APC ARHGDIG ATOH7 B3GAT1 BCAN BEX5 BRINP2 C2CD4C C2ORF80 C3ORF14 CA11 CAMK2A CAMK2N1 CCDC85B CCK CNTN5 COPS9 COX6A1 CPLX2 CPNE6 CSPG5 CTNNA2 CTNND2 DEAF1 DLL3 DOK6 DRD5 ELFN2 ENC1 ENHO EPHA5 ERC2 FAM107A FBXO2 FDX2 FGF13 FXYD7 GAP43 GNG2 GNG3 GNG4 GPM6A HPCAL4 HSD11B1L IDS KCNK4 KCNN1 KCNV1 LAGE3 LHX2 LINGO1 LMO3 LY6H LYRM9 MAP2 MAPK8IP2 MEIS3 MMD MT3 MYRIP NANOS3 NCAM2 NCS1 NECAB2 NPTXR NRG3 NSMF NTNG2 OLFM1 PACSIN1 PCDH11Y PHACTR3 PLPPR5 PPP4R4 RAPGEF4 RASL10A SFXN5 SHANK1 SLC17A7 SLC25A18 SLC30A3 SLC38A8 SNCG STK32C STOX1 STUM SYN2 TAAR6 TAAR8 TFAP2D TFPT TMEM160 TSPOAP1 TTC9B TUBB2A UCMA WSB2 YWHAH Brain - Hypothalamus Male 40-49 Up ACHE ADCY8 ADCYAP1 AIRE ANKRD34C B3GAT2 B4GAT1 BSX C10ORF105 C1ORF87 C2ORF50 CALB2 CALCR CALY CENPVL3 CLEC19A CNGB1 CRHBP CSMD3 CXXC4 DIRAS3 DLX1 DNER ECE2 FEZF1 FNDC9 FOXB1 GABRA3 GABRG1 GABRG3 GABRQ GAD1 GLRA2 GMNC GNG2 GNG4 GPR179 GPR45 GRIK1 GRIN3A GRM7 GSX1 HAP1 HCRT HCRTR2 HDC INPP5F KCNE5 KNCN LHX5 LRAT LRRC55 LUZP2 MAGEE2 MAGEL2 MC3R NAP1L5 NGB NPSR1 NXPH1 OPRK1 PABPC1L2A PABPC1L2B PCDH11Y PCDH19 PEG10 PEG3 PMCH PNMA2 PNMA5 PRDM12 PRDM13 QRFPR RAB3C RND2 RPE65 RTP5 SCG2 SCOC SEZ6L SLC17A6 SLC6A11 SMIM17 SOX1 SOX11 SOX14 SYT6 TACR3 TMEM17 TMEM196 TMEM255A TMEM35A TUBB3 UNC5D VAT1L VSTM5 VWC2L WDR49 ZBTB8B ZCCHC12 Brain - Spinal Cord (Cervical C-1) Male 40-49 Up ABCA2 AGPAT4 ANKRD40 ANLN APLP1 BACE1 BCAS1 C21ORF91 CA14 CARNS1 CDK18 CHADL CLDN11 CLDND1 CMTM5 CNDP1 CNP CNTN2 CNTNAP4 CTNNA3 DBNDD2 DPYSL5 DYNC1LI2 ENPP6 ERMN EVI2A FA2H FEZ1 FGFR2 FMNL2 FNTB GAL3ST1 GFAP GJC2 GPM6B GPR37 GPR62 HAPLN2 HMSD HOXB8 HOXD1 KLHL32 KLK6 LANCL1 LHPP LRRC63 MAG MARCKSL1 MBP MOBP MOG MTMR10 MTURN MVB12B MYRF NIPA1 NKAIN2 NKX2-2 NKX6-2 OR2L13 OR2L2 OR9A2 PAQR4 PAQR6 PAQR8 PEA15 PEX5L PIP4K2A PKP4 PLEKHB1 PLP1 PRR18 PRRG1 RAPGEF5 RASSF2 S100B SEC14L5 SEMA4D SIRT2 SLAIN1 SLC44A1 SLC5A11 SLC6A5 SPOCK3 STMN4 SYNJ2 TBC1D12 TF TMEM144 TMEM151A TMEM88B TNFRSF21 TP53INP2 TRAK2 TTYH2 TUBA1A UGT8 ZFP57 ZNF488 ZNF536 Kidney - Cortex Male 40-49 Up ACMSD ACY1 ACY3 AGMAT AGXT2 AK4 ALDOB AQP2 AQP6 ATP6V0A4 ATP6V0D2 ATP6V1B1 ATP6V1G3 BBOX1 BHMT BHMT2 BPHL BSND C11ORF54 CDH16 CLCNKB CLDN16 CLEC18B CLEC18C CMBL CRYL1 CTXN3 CUBN CYS1 DCDC2 DDC DEFB1 DHDH DMRT2 DUSP9 EMX1 FMO1 FOXI1 FXYD2 FXYD4 GATM GBA3 GGACT GLYAT GLYATL1 HAO2 HNF1B HOGA1 KCNJ1 LGALS2 LYG1 MCCD1 MIOX MSRA NAT8 NPHS1 NPHS2 PAX2 PBLD PDZK1 PDZK1IP1 PEPD PODXL PRODH2 PTGER1 PTH1R PTPRO RBP5 REN RHBG RNF183 RNF212B SFXN2 SLC12A3 SLC13A3 SLC22A11 SLC22A12 SLC22A13 SLC22A2 SLC22A6 SLC22A8 SLC34A1 SLC34A3 SLC47A2 SLC4A9 SLC5A10 SLC5A12 SLC5A2 SLC6A13 SLC6A18 SPP1 SUCLG1 TINAG TMEM174 TMEM213 TMEM52B TMEM72 TRIM6 UMOD WNT9B Brain - Cerebellum Male 70-79 Up ABCG4 ADAM11 ALS2 ARHGEF33 BAHCC1 BARHL1 BARHL2 BRICD5 CACNA1A CACNA1G CARMIL3 CBLN1 CCDC175 CDH15 CECR2 CELSR3 CHD7 CKMT1B CLK4 CNPY1 COL13A1 CRTAM DISP2 EN2 FAM131C FGF17 FLT3 GABRD GNG13 GRIN2C GRM4 IGLON5 KCNAB3 KCNC1 KCNK9 KHDC3L LGALS16 LHX1 MAP1LC3B2 MAST1 MCF2L MDGA1 MEGF11 MMP24 MTCL1 MYT1 NBPF20 NEUROD2 NKX6-3 NPTX1 OTX2 PAGR1 PAX6 PKD1 PPFIA4 PRR35 PRRT2 PRSS51 PTH2 PVALB RAB26 RGS11 RHBDL1 SBK1 SCN2A SCRT2 SHISA8 SKOR1 SLC1A6 SLC22A31 SLC35F4 SLC6A7 SRRM3 SRRM4 ST8SIA5 STRC TENM1 TFAP2E TLX3 TMC2 TMEM132E TMEM145 TMEM151B TMEM178A TMEM266 TNFRSF25 TRIM3 TRIM67 TRIM9 UBAP1L UNCX VSX1 VWC2 XKR7 ZFYVE28 ZIC2 ZIC3 ZIC5 ZNF382 ZSCAN10 Minor Salivary Gland Female 40-49 Up AGFG2 AGR2 ALDH1A3 ALX1 AMTN ANKRD36C ASCL3 AZGP1 BIK BPIFB2 C6ORF58 CCDC160 CCL28 CEACAM6 CHST9 CLDN24 CRACR2A CRACR2B CRISP3 CXCL17 DEFB1 DEFB105B EHF ELF5 ENPP3 ENTPD3 ERN2 FAM3B FAM3D FBN3 FDCSP FUT2 FUT3 FUT6 GALNT3 GALNT4 GALNT5 GALNT6 GALNT7 GLYATL2 GOLM1 GPR21 GPRC6A KCNN4 KRT7 LACRT LHX8 LPO LRRC26 LRRC31 LTF LYZ MIA3 MLPH MMP27 MMP7 MRGPRX3 MUC16 MUC19 MUC5B MUC7 MYBPH NAALADL2 NKX2-6 NXPE2 ODAM OTX1 PANX3 PAX3 PIGR PIP PLEKHS1 PLPP2 PROM1 PRR27 PRR4 PRSS22 RNASE8 RNF183 RUNX1 SCNN1A SLC6A14 SLITRK6 SLPI SOX9 SPDEF SPINK14 TCN1 TFCP2L1 TGFB2 TMC5 TMEM200C TMEM63A TNFSF15 TOX3 TRPV4 VGLL1 WFDC2 ZG16B ZNF552 Colon - Sigmoid Male 70-79 Up ACTG2 ADAM33 ARHGEF25 ATF4 ATP2B4 BAG2 BOC CACNA1C CACNA1H CHRM2 CHRNA3 CNGA3 CNN1 COL6A1 CSRP1 DCHS2 DCP1B DES DHX35 DPT EMILIN1 FAM89B FBXL22 FNDC1 FOXF1 FOXP2 FXYD6 GDNF GFRA1 GJC1 GLP2R HAND1 HAND2 HMCN2 HOXA11 HOXB2 HOXB3 HOXB4 HOXD10 HOXD11 HOXD12 HOXD13 HOXD9 IL17RD ILK KCNN3 KCNQ4 KIZ KLHL23 LIMS2 MAB21L2 MEIS1 MID1 MORN5 MRGPRD MRGPRF MYH11 MYL6 MYL9 MYLK NKX2-3 NKX3-2 NME4 NRP2 NTSR1 OLFML2A OPTC OR8S1 P2RY1 PBX3 PDLIM4 PDLIM7 PHOX2B PIEZO2 PLA2G2C PLEKHO1 PNCK PPP1R12C PRPH PTGFRN RAMP1 REEP1 RGS10 ROR2 SLC5A7 SMTN SSC5D STON1-GTF2A1L SUPT20HL1 SYNM SYT10 TACR2 TEAD3 TES TSPAN11 TSPAN2 VIPR2 WFDC1 WNT5B ZACN Spleen Female 20-29 Up ABI3 BANK1 BATF2 BTN3A1 BTN3A3 C1QA C1QB C1QC CABP4 CARD9 CASP10 CCL14 CCL24 CCM2L CD160 CD163L1 CD180 CD19 CD1D CD5L CD72 CD79B CD8A CERKL CNR2 CPLX3 CR2 CSF1R CXCL13 CXCL6 CXCR5 DNASE1L3 DOCK8 EMID1 EXOC3L1 FAM43A FAM9C FCRL1 FCRL2 FCRL3 FCRL5 FES FGD2 FHOD1 FLI1 GAB3 GDF3 GDPD2 GDPD5 GPR142 GPR182 GRAP GSDMD HLA-DOB HYAL1 HYAL2 ITGAD KAZALD1 KAZN KIR3DL3 LILRA4 LILRB5 LRTM1 MPEG1 MS4A7 MZB1 NKX2-3 NLRC3 NLRC5 NOS3 NOX5 NPY1R NR5A1 NTN4 OR2AJ1 OR5AK2 OR9G4 P2RX5 P2RY6 P3H2 PARP15 PDE2A PDLIM2 PITPNM3 PRR5L PSTPIP2 RENBP SCN11A SEMA3D SIGLEC12 SLC9A5 SPIC STAB1 STAB2 TLX1 TMC8 TMEM26 TRAPPC3L TTC24 VCAM1 Minor Salivary Gland Female 20-29 Up AGFG2 ALDH1A3 AMTN ANKRD36C AZGP1 BACE2 BARX2 BIK C4ORF19 C6ORF58 CBR3 CCDC15 CCDC160 CCL28 CD24 CEP41 CES5A CHST9 CLDN10 CRACR2A CRACR2B CRISP3 DEFB1 DMRTA1 DNASE2B DUSP23 EHF ELF5 ENPP3 ENTPD3 FAM3D FBN3 FDCSP FUT2 FUT6 GALNT4 GDF5 GLYATL2 HTR3A KCNN4 KRT23 KRT3 KRT7 LPO LRRC26 LYZ MGAM2 MLPH MMP7 MUC16 MUC19 MUC7 MYO5B NAALADL2 NKX1-2 NKX2-6 NXPE2 ODAM OR9G4 OTX1 PANX3 PDZK1IP1 PIGR PIP PLEKHS1 PLPP2 PROM1 PRR4 PRSS8 PTH2R RAD51B RHCE RHD RNASE8 SCGB3A1 SERINC2 SH3BP4 SLC28A3 SLC31A2 SLC37A2 SLC6A14 SLITRK6 SLPI SOX4 SPINT1 SVOPL TACSTD2 TCN1 TGFB2 TIGD2 TMED3 TMEM200C TNFRSF11A TNFSF10 TRPV4 VTCN1 WWC1 ZG16B ZNF552 ZSWIM4 Kidney - Cortex Male 30-39 Up ACMSD ACY1 ACY3 AGXT2 AMACR AQP2 AQP6 ATP6V0A4 ATP6V0D2 ATP6V1G3 BBOX1 BSND C11ORF54 CDH16 CDH6 CLCN5 CLCNKA CLCNKB CLDN16 CLDN2 CLEC18A CLEC18B CLEC18C CYS1 DCDC2 DDC DHDH DMRT2 DUSP9 EMX1 ESRRB FMO1 FOXI1 FXYD2 FXYD4 GALNT14 GGT1 HAVCR1 HNF1B HOGA1 HOXD8 IL17RB KCNJ1 KCP KIF12 KL LRP2 LY6L LYG1 MCCD1 MIOX NAT8 NPHS1 NPHS2 PAX2 PDZK1 PDZK1IP1 PKHD1 PTGER1 PTH1R RBP5 REN RIPPLY1 SLC12A1 SLC12A3 SLC13A1 SLC13A3 SLC16A4 SLC17A1 SLC17A3 SLC22A11 SLC22A12 SLC22A13 SLC22A2 SLC22A6 SLC22A8 SLC2A9 SLC34A1 SLC3A1 SLC47A2 SLC4A9 SLC5A10 SLC5A2 SLC6A13 SLC6A18 SLC7A13 SPP1 TINAG TMEM139 TMEM174 TMEM207 TMEM213 TMEM52B TMEM72 TRPV5 UGT1A9 UGT2B7 UGT3A1 UMOD UNC5CL Esophagus - Mucosa Male 70-79 Up BARX2 BICDL2 C18ORF25 C1ORF116 C6ORF132 CALML3 CAPN1 CLIC3 CNFN CRABP2 CRCT1 CRNN CSTA CSTB CYSRT1 DSG3 DTX2 ECM1 EMP1 ENDOU EPHA1 EPHA2 EPS8L1 EPS8L2 ESPL1 EVPL EVPLL FABP5 FAM83A FAM83H FOXI2 FUT3 FUT6 GIPC1 GJB2 GJB6 GNA15 GPR157 GPR78 GRPEL2 IGFL1 IL1RN KRT13 KRT6C KRT78 LAD1 LEXM LYPD2 MAL MALL MROH6 MUC21 N4BP3 NCCRP1 NECTIN1 NMU OTOP3 PADI1 PAX9 PITX1 PKP3 PLD2 PLEKHM1 PPL PRSS27 PTK6 RAET1E RAET1L RAP2B RBBP8NL RHCG RHOD RHOV RIPK4 RNF222 RNF223 S100A14 S100A16 S100A2 SERPINB13 SH3GL1 SIM2 SMAGP SOX15 SPRR3 TGM1 TGM3 TMEM184A TMEM40 TMEM79 TMPRSS11B TP53I3 TTC22 TTC9 TTLL12 UPK1A USH1G VSIG10L ZNF185 ZNRF1 Esophagus - Muscularis Male 70-79 Up ACTG2 ADAMTS19 ADAMTSL1 ADRB3 ARHGEF39 CACNA1H CACNB2 CDHR3 CKB CNN1 CNTNAP3 COL4A5 COL4A6 COL6A1 CSRP1 CUEDC1 CYS1 CYSLTR1 DENND2A DES DHX35 DMPK DNAJB5 DPYSL3 EDA EXD3 F2RL2 FAM149A FAM83D FBXL22 FLNA FNBP1 FOXF1 FOXF2 FOXP1 GIPC3 HLF HOXA3 HOXA4 HOXB2 HPSE2 HS1BP3 IGHMBP2 ITPKB JPH2 KCNQ4 KIAA0753 LAMA4 LHCGR LIMS2 MAS1L MRGPRD MRGPRF MYH11 MYL6 MYL9 NKX6-1 NPEPL1 NRP2 NRTN OTOGL P2RX2 PDLIM7 PGM5 PKIG PLEKHO1 PPP1R12C PRKG2 PYGB RBPMS REEP1 RGMB RNF216 SEMA3A SLC2A9 SLC5A7 SMTN SRF SSC5D SYNM THBS3 TPBG TPCN2 TPM2 TPPP3 TPSG1 TRMT61A TRPC6 WNT5B Prostate Male 70-79 Up ALDH1A3 AMD1 ANO7 AR ARTN BMP4 BMP5 CDC42EP5 CFAP69 CGNL1 CHD3 CHRNA2 CLEC4F COL16A1 CPA6 CREB3L4 CRISPLD2 CST1 CYB561D2 DEFB136 DUX4 EBF4 EPHA3 EVX1 FAM118A FOXA1 GATA2 GATA5 GCNT2 GLIS1 GSTM2 HIC1 HOXA13 HOXB13 HOXD10 HOXD12 HOXD9 HSF4 IGF1 INAFM1 ISL1 KLK2 KLK3 KLK4 LPAR6 MESP1 MKX MMP23B MSMB NBL1 NKX3-1 NTF4 NTN5 NTRK1 OR51E2 P2RX2 PABPC4L PAGE4 PAK1IP1 POTEH POTEM POU5F1B PRAC1 PRAC2 PRDM8 RDH11 RIPPLY3 RLN1 SCUBE2 SERPINB11 SLC14A1 SLC15A2 SLC30A4 SLC45A3 SMO SPDEF SRD5A2 STEAP2 STRA6 TBL1X TGFB3 TMCO4 TMEM26 TMPRSS2 TNFSF15 TRPC4 TSLP TTC6 TTLL3 TULP1 UPK3A WNT2 XKR5 ZNF226 ZNF350 ZNF613 ZNF615 ZNF761 ZNF816 ZNF888 Small Intestine - Terminal Ileum Male 70-79 Up ADAM28 ADAMDEC1 AIM2 ANKRD44 ANKRD49 ANXA2R ARL17B BANK1 BLK BTN3A1 C17ORF67 CABP4 CACNA1F CASP8 CCL19 CCL21 CCR9 CD19 CD40LG CD6 CD96 CLEC2D CTLA4 CXCR4 DDX11 DEFA5 DEFA6 DEFB105B DEFB107B DGKA E2F5 ENTPD4 ERAP2 FAM177B FCRL1 FCRL2 GFI1 GPR152 GPR171 GPR174 GSAP HELB HLA-DOB ICOS IL2 IL24 IL2RA IL7R IRF3 ITK KLHL6 KLRB1 KLRC4 MADCAM1 MBOAT4 MUSK NKX2-3 NLRC3 NPIPB12 NPIPB4 OFD1 OR13A1 OR52N4 OR56B1 OR56B2P OR5D14 PDE7A PHOX2B PLEKHG7 PLET1 PLXDC1 PYHIN1 SAP25 SCML4 SHISA3 SIRPG SLC25A53 SLFN14 SP140 SP140L SUMO4 TIGIT TMC8 TMEM156 TNFRSF13C TP53INP1 TRAF5 TRAT1 TSPAN11 TTC13 UBASH3A UTS2B ZBTB25 ZNF107 ZNF253 ZNF266 ZNF80 ZNF831 ZNF860 ZNF92 Colon - Transverse Male 70-79 Up ACTG2 ASIC5 BAG2 CCL11 CDHR3 CHRM2 CHRNA3 CNN1 DPT FOXF1 FOXP2 GALR2 GIP GJC1 GLP2R GREM2 HAND1 HAND2 HOXB2 HOXB4 HTR3A KLHL23 LRRC3 MAB21L2 MADCAM1 METTL24 MID1 MYLK NKX2-3 NKX3-2 NPY4R NTSR1 PHOX2B PIRT PLA2G2C PPP1R12C PRPH PTGFRN ROR2 S100G SLC5A7 STON1-GTF2A1L SYDE2 SYNM TACR2 TLX2 TNFAIP8L1 TSPAN11 TSPAN2 VIP ZACN Liver Female 40-49 Up ABCB4 ABCC2 ABCG5 ABCG8 ACOT12 AGT AGXT AKR1C4 ALDH8A1 AMBP ANG ANGPTL3 APCS APOA5 APOB APOC2 APOC4 APOF APOH ASGR1 ASGR2 C2 C4BPA C4BPB C5 C8A C8B C8G C9 CCL16 CFB CFHR1 CFHR2 CFHR3 CFHR4 CFHR5 CFI CLEC4M COLEC10 CP CPB2 CYP2C9 CYP2D6 CYP2E1 CYP8B1 F11 F12 F2 F7 F9 FCN2 FGL1 GC GCGR GDF2 GLTPD2 HABP2 HP HPD HPX HRG HSD17B6 IGFALS INHBE ITIH1 ITIH2 ITIH3 ITIH4 KLKB1 KNG1 MASP2 MAT1A MST1 OIT3 ORM2 PAH PLG PON3 PZP RBP4 RDH16 RTP3 SAA4 SERPINA10 SERPINA11 SERPINA6 SERPINA7 SERPINC1 SERPIND1 SERPINF2 SLC17A2 SLC22A9 SLC38A4 SLCO1B3 SMLR1 TFR2 TMEM176A TTPA UGT2B4 VTN Artery - Coronary Male 70-79 Up ADAMTS1 AEBP1 ANTXR1 ARHGEF39 ARL4AP5 ART4 ASPN BAG2 BDNF BGN BLID C11ORF96 C1ORF54 CA5B CCDC3 CCDC81 CCL2 CFH CMKLR1 COL10A1 COL21A1 CPXM2 CRIP1 CTAG1B DNAJB4 DUXA ECM2 ENAH EOGT EPHA3 FAM180A FILIP1L FMOD FOXC1 FOXC2 FOXL1 FOXS1 GEM HAUS7 HES4 HEYL HMCN1 ID4 IGFBP7 INHBA KALRN KCNA5 KCNK15 KCNT2 LGR6 LIMS4 LRRC32 LTBP1 LTBP2 MAP3K7CL MEGF6 MFAP4 MFGE8 MGP MKX MSC MTHFD1L MTMR8 MYO1D NFATC2 NOX4 NTF3 OGN P4HA3 PCDHB8 PDE4C PDGFA PKIG PLAC9 PLXDC2 PPP1R14A PRELP PRKG1 PTTG2 RNF152 RNF180 SCARF2 SELENOM SPARCL1 ST6GALNAC5 SUGCT TAGLN TAS2R30 TBX18 TBX2 TM4SF1 TMEM47 TNFAIP8L3 TRPC4 VCAN WTIP Artery - Aorta Male 70-79 Up ADRA2C AEBP1 ANKRD37 ANO1 ANTXR1 BGN C1QTNF8 C5ORF46 C8ORF34 CARTPT CDH13 CLEC18A COL14A1 COL21A1 CPXM2 CRISPLD1 CYTL1 EFEMP1 ELN EXT1 FBLIM1 FBLN5 FGL2 FMOD FOXC1 FOXC2 FOXS1 FRZB GABRR1 GADD45B GAS6 GDF7 HAPLN3 HAUS7 IGFBP2 IGFBP7 IL13RA2 ITGA10 ITGA11 ITGA8 ITGB5 KALRN KCNA5 KCNK15 KCNK17 LDOC1 LGR6 LIMS3 LIMS4 LOXL1 LTBP1 LTBP2 LTBP3 MAGEC3 MEGF6 MFGE8 MGP MRAP2 MYH10 MYH9 MYO1D NAV1 NOX4 NPR1 NXPH3 OGN OMD PCDH11X PCDH7 PCDHB16 PDGFC PID1 PLD5 PLS3 PLXDC2 PMEPA1 PPP1R3C PRDM16 PRDM6 PRKG1 PROS1 PTGIS SLC14A1 SLC27A3 SMAD7 SMOC2 SNURF SOD3 SOST ST6GAL2 STAC SUSD5 TBXA2R THBS2 TPH1 TRAF5 USP35 VCAN WWP2 ZNF395 Liver Male 70-79 Up A1BG A1CF ABCG8 ACADSB ACOT12 ACSM5 ADH1A ADH4 ADH6 AGXT AHSG AKR1C4 AKR1D1 ALB ANG ANGPTL3 APOA1 APOA2 APOC1 APOC2 APOC3 APOC4 APOH APOM ARID3C BAAT BHMT BHMT2 CFHR1 CFHR2 CYP1A2 CYP2A6 CYP2A7 CYP2C8 CYP2C9 CYP2D7 CYP4A11 CYP4A22 DCXR DHTKD1 DMGDH EHHADH ELFN1 F13B F7 FETUB FMO3 GLYAT GLYCTK GRHPR GSTA2 GYS2 HAAO HAO1 HRG HSD17B13 ITIH2 KLKB1 KNG1 LBX2 LIPC LPA MAT1A MBL2 NPW NR1I3 OTC PAH PGLYRP2 PIPOX PKLR PON1 PROC RBP4 RTP3 SARDH SERPINA11 SERPINA4 SERPINC1 SERPIND1 SHBG SLC10A1 SLC22A1 SLC22A25 SLC22A7 SLC22A9 SLC27A5 SLC2A2 SLC30A10 SLC38A3 SLCO1B3 SPP2 TM4SF4 TMPRSS6 TTC36 TTR UGT2B10 UGT2B15 UPB1 UROC1 Whole Blood Female 70-79 Up ACAP1 ANKRD55 AOAH ARRB2 BCL2A1 BIN2 BST1 C11ORF21 CAMP CARD16 CCL4 CCL4L2 CCL5 CCR3 CD160 CD177 CD2 CD244 CD247 CD300A CD300E CD3D CD3E CD3G CD40LG CD8A CD8B CD96 CEACAM3 CLEC4A CST7 CTSW CXCR4 CYTIP DEDD2 DOK2 FASLG FCAR FCGR3A FCGR3B FCN1 FCRL6 GNLY GRAP2 GZMA GZMB GZMH GZMK GZMM HCST HLA-B HRH4 HSPA6 IFNG IL2RG ITGAL ITGAM ITK JAML KLRB1 KLRC1 KLRD1 KLRF1 KLRG1 KLRK1 LCK LCP2 LIM2 LST1 MXD1 NCR1 NCR3 NKG7 OR51B2 OR51G2 PLAUR PRSS57 PSTPIP1 PYHIN1 RAC2 RGL4 RYBP S100A12 SAMD3 SH2D1A SH2D1B SLC2A3 TAGAP TBC1D10C TBX21 TIGIT TMEM71 TRAT1 TSPAN32 VNN2 VSTM1 XCL1 XCL2 ZAP70 ZDHHC19 Brain - Hippocampus Female 70-79 Up ABCG2 ADAP1 ADARB2 AK5 AMER2 C12ORF76 C1QL2 CCDC85B CCK CNIH2 COPS9 CSAG1 FAM107A FXYD7 GPR37 GPR62 HDDC2 IFNA6 KCNG4 KCNMB4 KCNN1 KLHL32 KLRC2 KLRC3 LY6H MT3 NANOS3 NECAB1 NEUROG1 NKX6-2 OLFM1 OLIG1 OLIG2 OMG OPALIN OR4F29 OR4F5 PCDH9 PDE6B PEX5L PHACTR3 PIP4K2A PRR18 QDPR RAPGEF4 SHTN1 SLC24A2 SLCO1A2 SLITRK1 SOX8 TBR1 TFPT THEMIS TMEM160 TMEM235 TMPRSS5 TNR TTYH2 Brain - Caudate (Basal Ganglia) Female 70-79 Up ACBD7 ACSBG1 ADCYAP1R1 AHCYL1 ANKRD34B AQP4 ATP1B2 C1ORF87 CABLES1 CDH20 CERS1 CGB2 CHAT CHI3L1 COA6 CORT CPE CRB2 CSAG1 DDAH1 DEFB116 DTNA ETNPPL GABRA2 GABRA4 GABRB1 GABRG1 GBX2 GNG7 GPC5 GPR143 GPR75 GPR88 GPRC5B HHIPL1 HRH3 HS3ST5 IFNA6 IL17D KCNH4 KHDC1L LCN9 LGI1 LHFPL1 LHX8 LIX1 LRP4 MAPK4 MC4R MEGF10 MLC1 MRO NDP NEUROG1 NKAIN3 NPAS3 NPY NR2E1 NTRK2 NTSR2 NWD1 OPHN1 OR10A2 OR1S2 OR2AJ1 OR4F29 OR4K2 OR8K3 PDE1B PITPNC1 POLN PON2 POU3F4 PPP1R1B PRAMEF26 PRSS35 PSD2 PTPRZ1 RANBP3L RESP18 RGR RGS20 RGS9 RLBP1 RYR3 SLC18A3 SLC1A2 SLC1A3 SLC5A7 SLC6A12 SLC9A7 SLCO1C1 SNX32 STON2 STOX1 SYNDIG1L SYNPR TNIK TRPC3 TUBB2B Brain - Hypothalamus Female 70-79 Up ARHGEF33 ASPA ATG4C BCAS1 BSPH1 C10ORF90 C12ORF76 C18ORF32 CA8 CALB1 CARNS1 CERCAM CHADL CLDND1 CLEC19A CLEC9A CMTM5 CNDP1 CNP CNTN2 COLGALT2 CTNNA3 DBNDD2 DNER DYNC1LI2 ERMN EVI2A FABP7 FAM107A FAM181B FAM222A FEZ1 FGF1 FGF20 FOXO4 GNG13 GOLGA7 GPR62 GRID2 HAPLN2 HIPK2 HOMER3 IFI27L2 IFNA6 KCNG4 KIF6 KLHL32 KLRC2 LHFPL3 LHPP LPAR1 MAP6D1 MBP MOBP MOG MT3 MTURN NDRG2 NEUROG1 NIPAL3 NKX2-2 NKX6-2 OLIG1 OLIG2 OR4F29 OR4F5 PAAF1 PAIP2B PAQR6 PCP2 PDE6B PIP4K2A PKP4 PLEKHB1 PPP1R17 PRR18 PSRC1 PVALB QDPR RAB11FIP4 RFTN2 RND2 ROM1 S100B SCD5 SH3GL3 SHTN1 SLAIN1 SLC5A11 SLCO1A2 SOX8 SPINK6 SPOCK3 SYNDIG1 TMEM144 TMEM235 TMEM74 TMEM88B TNR TP53INP2 Skin - Sun Exposed (Lower Leg) Female 70-79 Up AADACL2 ALOX12B ALOXE3 ARSF ASPRV1 ATP6V1C2 C1ORF68 CALML5 CARD18 CASP14 CCER2 CDH3 CDSN CHRNA9 CLEC2A CMA1 CTNNBIP1 CXADR CXCL14 DLX5 DMKN EDN2 EGLN3 ELOVL4 EREG FLG GSDMA GSDMC HOPX IDE IFFO2 IGFL2 IL18 IL36B IL36G IL36RN KLK5 KLK7 KLRF2 KPRP KRT10 KRT14 KRT17 KRT2 KRT23 KRTDAP LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE4A LCE5A LCE6A LGALS7B LGALSL LIPM LYPD5 METRNL MMP27 NDRG1 NECTIN4 NIPAL4 OR10V1 PGLYRP4 PLA2G3 PLA2G4E POF1B PSAPL1 PTGES RAB38 RNF39 S100A7A SAPCD1 SBSN SDR16C5 SDR9C7 SERPINA12 SERPINB4 SERPINB7 SERPINB8 SLC10A6 SLC52A1 SP5 SPRR2B SPRR2G STARD5 SYT8 TMEM45A TMPRSS13 TUFT1 UNC93A XCR1 XG XKRX Adipose - Subcutaneous Female 70-79 Up ABCD2 ACER2 ACKR3 ACO1 ADCY4 ADGRL4 ADRA2A AGPAT2 AGTR1 AIFM2 ANGPT2 ANGPTL4 ANGPTL8 APOL3 ARHGAP20 ATP8B4 AVPR2 CD248 CIDEC CPNE8 CXCL12 CYGB CYP19A1 DEFB132 DGAT2 DLL4 EBF1 EBF3 ELMOD3 ELOVL5 ESYT1 FAM124B FAM13A FAM89A FASN FZD4 GFRAL GPAM GPD1 GPIHBP1 GPR146 GRK3 GYG2 HILPDA HOXC5 HTR1F IGF1 INHBB IRX6 ITGB1BP1 KDM7A KLB LGALS12 LPL LRRC32 LRRC8C MAS1L MEOX1 MFAP3 MMRN2 MOCS1 MYCT1 MYEOV NCOA7 NR1H3 NSDHL OPN4 PCSK5 PDGFRB PHLDA3 PKD1L2 PLIN2 PLIN4 PLXND1 PNPLA2 PPARG PRRT4 PRRX1 PTGES RAPGEF3 RDH5 RETSAT S1PR1 SCD SLC25A1 SPAAR SPRY1 STAT5A STEAP4 TACR1 THRSP TIE1 TLL1 TMEM135 TNFAIP3 USHBP1 VKORC1L1 ZNF366 ZNF548 ZNF593 Nerve - Tibial Female 70-79 Up AATK ABCA10 ABCA8 AHR ARHGAP39 ARHGEF10 ASPA BEST1 BIRC7 BMP8B C2ORF88 CDH19 CHL1 CLDN19 COL28A1 CYP2U1 DCLK3 DEFB110 DEFB112 DEFB116 EHBP1 ENTPD2 FIGN FOXD3 GAS2L3 GFRA3 HSPA12A IFNA14 IFNA16 IFNA17 IFNA4 INF2 ITGB8 KANK4 KIF19 LCTL LGI4 MIA MICALL2 NEK1 OR10G9 OR10Z1 OR11H2 OR13C3 OR13F1 OR1L4 OR2G3 OR2J1 OR2M2 OR2M3 OR2M7 OR2T1 OR2Z1 OR4C15 OR4C46 OR4K17 OR4K5 OR4L1 OR4N5 OR51A4 OR52E8 OR5AR1 OR5D13 OR5D14 OR5D16 OR5H15 OR5L2 OR5T3 OR6C65 OR6C70 OR6Y1 OR8H1 OR8H3 OR8I2 OR8J1 OR8J3 OR8K3 OR8U1 OR9K2 PLAG1 PLEKHA4 PLXNB3 POLR2F PRAMEF17 PRIMA1 PTPDC1 SBSPON SCN7A SEMA3B SHC4 SHH SLC25A48 SLITRK5 SORCS1 SYT10 TAAR8 THSD7A TLDC2 TMPRSS5 USP17L13 Muscle - Skeletal Female 70-79 Up AMPD1 APOBEC2 ASB16 BEST3 C1ORF127 CACNB1 CACNG1 CACNG6 CALML6 CAND2 CAP2 CAPN3 CAV3 CHRNA1 CHRNB1 CHRND CHRNG CLCN1 CLTCL1 CORO6 CUTC DNASE1L1 DUSP13 FAM184B FGGY FHL3 FXR1 GAMT IP6K3 JPH1 JSRP1 KLHL30 KLHL33 KLHL41 LBX1 LMOD3 LRRC30 LRRC38 MACROD1 MAMSTR MAPK12 MSS51 MYBPC1 MYBPH MYF6 MYH1 MYH8 MYLK2 MYOG MYOZ1 MYPN NEB OPTN OSBPL6 P2RX6 PCNT PDLIM3 PFKM PGM1 PGPEP1L PHKG1 PHYH PITX3 PLA2G4C POPDC3 PPP1R3A PRKCQ PTGES3L PYGM RAPSN RBM24 RHOBTB1 RPL3L RPUSD4 RTN2 SESN1 SIX1 SLC16A10 SLC29A2 SLC36A2 SLN SRPK3 STAC3 TACC2 TCEA3 TMOD4 TNNC2 TNNI2 TNNT3 TRDN TRIM54 TRIM72 TXLNB UBAC1 UBE2G1 UCP3 UNC45B USP6 YBX3 YIPF7 Breast - Mammary Tissue Female 70-79 Up AACS ABCD2 ABCG1 ABLIM3 ACACA ACACB ACLY ACSS2 ADGRL4 AGPAT2 ANGPTL8 ANO2 ARHGEF15 ARHGEF38 AVPR2 BMP6 BTNL9 CA4 CCL14 CCSER1 CD300LG CD320 CD36 CISH CMTM7 CX3CL1 CYP4Z1 CYYR1 DEFB132 DGAT2 DLAT DLL4 EDN2 ELOVL5 FAM124B FAM167B FAM89A FASN GABRP GPAM GPIHBP1 GPR146 GRK3 GSC HOXD8 HOXD9 ICAM2 INHBB IVNS1ABP JUN KIAA1217 KLB KRT17 LDB2 LGALS12 LPCAT3 LPL LRRC70 MAFF MEOX1 MMRN2 MOGAT1 MYCT1 NOSTRIN NOTCH4 NR1H3 NSDHL OR9Q1 OXTR PALMD PC PLEKHG1 PLIN2 PNPLA3 PPARG PTCHD3 RAPGEF3 RNF125 SCD SCGB2A2 SGK2 SLC25A1 SLC28A3 SLC5A4 SLC5A6 SPAAR SPRY1 SSC4D ST6GALNAC3 STAC2 THRSP TIMP4 TMEM135 TNFRSF4 TNMD USHBP1 VGLL1 VKORC1L1 VTCN1 ZNF366 Lung Female 70-79 Up A2M ACVRL1 ADAMTS8 ADGRG6 ADGRL2 AGER ANOS1 AQP1 BCL6B BIRC3 BMP5 C20ORF202 CALCRL CCDC102B CCL2 CDH5 CEACAM6 CLDN5 CLIC2 COL6A5 COL6A6 COX4I2 DOCK6 DPRX EDN1 EDN2 EGFL7 EMP2 FCN3 FGFR4 FLT4 FMO2 FOLR1 FUT1 GALNT18 GGTLC1 GPC3 GPER1 GPRC5A HAS1 HBEGF HECW2 HGF HIGD1B HTR3C IDO1 IL12A IL15RA IL6 INMT KDM6B LAMC3 LIMCH1 LTK MACF1 MS4A15 NCKAP5 NDNF NKD2 NR4A3 OR2A25 OVCH1 PALD1 PAPSS2 PCDH12 PHEX PIEZO2 PLEKHG1 PODXL PTGS2 RGCC RNF122 ROBO2 RSPO4 SFTA2 SH2D4B SHROOM4 SKIL SLCO4A1 SLFN11 SLIT2 SOCS2 SOSTDC1 SOX7 ST8SIA6 STARD8 TAL1 TBX2 TBX4 TCF21 TFPI TM4SF1 TMEM100 TMEM204 TMEM74B TSC22D2 VEGFD VIPR1 WNT2 WNT3A Skin - Not Sun Exposed (Suprapubic) Female 70-79 Up AADACL2 ACVR1B ACVR2A ADGRF2 ADGRF4 ALOX12B ANO9 ARSF ASCL2 BNIPL C3ORF52 CA12 CAPNS2 CARD14 CASP14 CCL27 CDX4 CENPP CLDN1 COL17A1 COL7A1 DEGS1 DLX5 DSC3 EGLN3 EXPH5 FAM83B GAL3ST4 GAN GATA3 GJB3 GJB4 HS3ST6 IGFL3 IL1RL2 IL20RA IL20RB IRF6 IRX3 KCNJ18 KCNK7 KLC3 KLF4 KLF5 KLRF2 KRT1 KRT14 KRT77 KRT80 KRTDAP LAMB4 LAMTOR4 LGALS7B LGALSL LIPK LIPM LY6G6C LYPD5 LYPD6B MATN4 MYCL NBPF26 NECTIN4 NIPAL4 NR1D1 OCM2 OR10A3 OR10A6 OR5P3 OVCH2 PGLYRP3 PLA2G4F PNPLA1 POU2F3 PPP1R14C RDH12 RDH13 RNF39 RORA SBSN SDR9C7 SLC10A6 SPTSSB STARD5 SYT8 TGM5 TINCR TMEM45A TNS4 TP63 TREX2 TUFT1 VAV3 WEE1 WFDC5 WNT16 WNT3 XCR1 XG ZNF273 Pituitary Female 70-79 Up ADGRD2 ALX3 ARC ARFGAP1 ASCL1 ASIC4 ASTN2 AVPR1B BAIAP3 C14ORF39 C17ORF107 C21ORF58 C2CD4A C7ORF50 CDKN2A CDRT4 CFC1 CGA CGB5 CHRNE CHST8 CLDN25 CLDN9 COL22A1 COL2A1 COL9A2 COQ8B CPNE7 CRABP1 CRHR1 CYP1B1 EDN3 EYA1 FAM86B1 FBXO16 FFAR4 FOXI2 FOXO6 FSHB GAGE10 GAL GCK GDF5 GJB7 GNB3 GNRHR GPR50 GRIK3 GRM6 HFM1 HTN3 INSM1 KCNH6 LEPR LHB LHX3 LMX1A MYO16 NEUROD4 NME3 NNAT NPTX2 NPW NUDT14 OR10G3 OTOG PCDH15 PCDHB1 PCSK1N PHF21B PILRB PLD3 POMC RAB3B RASD1 RAX RAX2 REC8 RNF224 RPEL1 RPH3AL SAMD11 SIX3 SIX6 SLC13A4 SLITRK1 STK33 TAC4 TBX19 TGFBR3L TMEM244 TMEM61 USP17L23 VMO1 VWDE ZBTB49 ZFR2 ZNF10 ZNF404 ZSCAN1 Thyroid Female 70-79 Up ACAD8 ARHGAP8 ATP13A4 ATP8A1 C16ORF89 CCL21 CDK10 CENPJ COL23A1 CORO6 CPAMD8 CRABP1 CRYBB3 CRYGN CTSB CYTH2 DAPK2 DIO1 EPOR FAM167B FOXE1 FRAS1 FSCN2 GAL3ST3 GLCCI1 GRK1 HEMK1 HHEX HIRA HOOK3 IFT140 INPP5J IVD IYD KCNJ16 KLHL14 KNSTRN LCN12 LIPG LRP2 MPPED2 MROH1 MRPS25 MSANTD2 MT1F MUC15 NKX2-1 NUPR1 OR2T33 PABPC1L PAN2 PAX8 PBX4 PCED1A PDE8B PKNOX1 PLA2G6 PLA2R1 PLEKHH1 PRKX PRSS16 PRTG PTCHD4 RCBTB1 RECQL5 RGL3 RHPN1 RTN4RL2 S100A13 S100A5 SALL4 SCX SH3D21 SHISA2 SLC16A11 SLC25A29 SLC26A4 SLC26A7 SLC4A11 SLC5A8 SMCO4 SNX22 TCERG1L TDRP TFF3 TG TLE6 TMEM125 TSHR TSTD1 TUBB8 WDR6 WDR72 WDR86 ZBED2 ZMAT4 ZNF114 ZNF486 ZNF804B ZNF90 Artery - Aorta Female 70-79 Up ACAN AEBP1 ANKRD6 ANO1 ANTXR1 ART4 ASPN ATP10A AVEN BGN C1QTNF8 C8ORF34 CA5B CDH13 CLEC18A COL21A1 COL8A1 COL8A2 CPXM2 CRIP1 CRISPLD1 CRYBB3 CTAG1A CTAG1B EFEMP1 ELN ENG FAM156B FAM180A FBLIM1 FBLN5 FBXO42 FMO2 FMOD FRZB GAS6 GDF7 GEM GNRH1 HAPLN3 HAUS7 HMCN1 ID3 IER5L IGFBP2 IGFBP7 ITGA10 ITGA11 ITGA8 ITGB5 ITGBL1 KALRN KCNK15 LIMS3 LIMS4 LOXL1 LTBP2 LTBP3 MAGEA2B MEGF6 MFGE8 MGP MRAP2 MYH10 MYH9 MYO1D NAV1 NAV2 NHS NOX4 NPR1 NXPH3 OGN OMD PDGFA PKD2 PLS3 PRDM16 PRDM6 PRELP PRKG1 PTGIS PXDC1 SCARA3 SCARF2 SMOC2 ST6GAL2 STAC SUGCT SULF1 SUSD5 TBXA2R THBS2 TINAGL1 TNFRSF11B TPH1 USP35 VCAN WWP2 ZNF385D Heart - Atrial Appendage Female 70-79 Up ACTC1 ADAMTS7 ADAMTSL2 ALPK2 ASPG BCO2 BMP10 C14ORF180 C17ORF107 CASQ2 CHRNE CIB2 COLQ CORIN COX6B1 CPNE5 CPT1B CRIP2 CSDC2 CYP2J2 DAND5 DHRS7C DKK3 DOK7 FABP3 FGF12 FITM2 GATA4 GJA3 GJA5 GRXCR2 GSG1L HAMP HCN4 HHATL HRC HSPB2 HSPB3 HTRA3 IGSF5 ITGB1BP2 KCNIP2 KLHL31 KRBA1 LAPTM4B METTL7B MTUS2 MYBPC3 MYBPHL MYH6 MYL4 MYL7 MYLK3 MYOZ2 NDUFA11 NDUFA8 NDUFAB1 NEBL NES NKX2-5 NKX2-6 NMRK2 NPPA NPPB NRTN OR10P1 OR4F29 OR8B8 PAM PLA2G5 PLPP7 POPDC2 PPP1R3G PRKAG2 PXDNL RABGAP1L RBPMS2 RD3L RILPL1 RNF207 SBK2 SBK3 SCN5A SHD SLC41A1 SLC4A3 SMAD6 SSTR5 TBX20 TBX5 TMEM182 TNNI3K TNNT2 TRIM55 TSPAN18 UQCC2 UQCR11 UQCRB VSTM2L WNK2 Heart - Left Ventricle Female 70-79 Up ASB11 CCDC141 CDH2 CHCHD10 CKMT2 COQ10A CORIN COX5A COX6A2 CPT1B DECR1 FABP3 FGF12 FGF18 FHL2 FHOD3 FITM2 GJA3 GOT1 HHATL HRC HSPB3 HSPB7 KCNJ8 KLHL31 LSMEM2 MLYCD MPC1 MYBPC3 MYH7 MYH7B MYL3 MYLK3 MYOM2 MYOZ2 MYZAP NDUFA1 NDUFAB1 NEBL NKX2-5 NMRK2 PDE1C PDE3A PKP2 PLN POPDC2 RD3L RYR2 SCN5A SDHA SGCG SLC16A7 SLC25A4 SLC41A1 SLC4A3 SLC8A1 SMCO1 SMYD2 TCF15 TCF24 TECRL TENM2 TMEM182 TNNI3 TNNI3K TNNT2 Adipose - Visceral (Omentum) Female 70-79 Up AACS AADACL4 ABCA9 ACLY ACSS2 AGPAT2 AIFM2 ANGPT2 ANGPTL8 ANO2 B4GALT3 BNC1 BRS3 BTNL9 C19ORF12 C7 CCDC71L CDKN2C CLDN15 CPXM1 DDX3X DGAT2 DLAT DPT DRD4 ECHDC1 ELOVL5 ELOVL6 FAM89A FASN FOSB GABRE GAS1 GFPT2 GLP2R GNG11 GPAM GPD1 GPR4 GRK3 GYG2 HAS1 HBEGF HLX HOXD9 IDO1 INSIG1 KLB LBHD1 LGALS12 LPL LXN MAFF ME1 MEDAG MGST1 MMP19 MOGAT1 MSLN MT1A MT1M MUC16 NFIL3 NMB NR1H3 NSDHL PAMR1 PC PLXNA4 PNP PNPLA2 PPARG PROCR PRRT4 PTPRQ RARRES1 RBP7 RDH5 ROBO3 SCD SLC1A7 SLC25A1 SLC7A10 SLFN11 SMIM3 SOX17 SPRY1 SRPX STEAP2 SVEP1 THRSP TIE1 TIMP4 TSHZ2 UPK3B VEGFC VIPR2 VKORC1L1 WNT11 ZNF232 Esophagus - Muscularis Female 70-79 Up ABL1 ACTG2 ADAM33 ADAMTS19 ANKS1A AQP1 ARSB ATL2 BCHE BOC BRS3 CACNA1H CACNB2 CCDC69 CHRM3 CMA1 CNGA3 COL4A5 COL4A6 CST5 CYSLTR1 DENND2A DES DHX35 DPYSL3 EML1 EPHA7 ERVFRD-1 F2RL2 FAM20C FBXO30 FNBP1 FOXF2 FOXP1 GIPC3 GPR161 HLF HMG20B HOXA4 HOXB2 HOXB3 HOXB4 HPSE2 HS1BP3 JPH2 KCNMB1 KCNQ4 KIAA0753 KLHL23 KLHL42 LGI2 LHCGR LSM11 MAS1L MS4A2 MYH11 MYL9 MYLK NFIA NKX6-1 NTN1 OR4C45 PLEKHO1 PPP1R12C PRKG2 PYGB QRFP RARB RBPMS RGMA RGMB RGS2 RPP21 RPS6KA5 RSPO3 S1PR3 SCARA5 SCMH1 SCUBE1 SEMA3A SLC27A6 SLC2A9 SLC9A9 SMTN STON1-GTF2A1L SYDE2 SYNM TEAD3 TMEM108 TNFSF12 TPBG TPSD1 TRIM47 TSPAN18 TTC23 USP12 WLS WNT9A WWTR1 ZNF511 Esophagus - Gastroesophageal Junction Female 70-79 Up ACTG2 CYSLTR1 KCNMB1 MT1A MYL9 PDLIM4 PNRC1 PRAMEF25 RASL11A RGS2 RPRM STON1-GTF2A1L TOX2 TPSD1 WNT9A Esophagus - Mucosa Female 70-79 Up ADH7 ANXA1 AQP3 ARL4D CALML3 CAPN1 CD164L2 CGB8 CLCA2 CNFN COMTD1 CRABP2 CSTB CYSRT1 DEFB104B DHRS1 DSC2 DSG3 E2F2 EMP1 ERVMER34-1 EVPLL FABP5 FAM110C FAM83H GALNT14 GBP6 GDPD3 GIPC1 GPR78 GSTP1 HES2 IFNE IL1A IL1RN KLK10 KRT15 KRT16 KRT5 KRT6A KRT6B KRT6C KRT78 LAD1 LPAR6 LY6D LYPD2 MGST2 MPZL2 MSGN1 NECTIN1 NLRX1 NMU OLIG3 OTOP3 PADI1 PAX9 PITX1 PLD2 PRDM1 PROM2 PTK6 RABGGTA RAET1L RARG RBBP8NL RHCG RHOD RNF222 RNF223 S100A14 S100A16 S100A2 SEMA4B SFN SIM2 SLC7A1 SLC7A5 SMAGP SOX15 SPINK7 SPRR1A SPRR1B TBX6 TGM1 TGM3 THSD4 TICRR TMEM184A TMEM40 TMPRSS11B TMPRSS4 TP53AIP1 TTC9 TTLL12 TXN TXNDC17 USH1G VSIG10L ZNF185 Colon - Sigmoid Female 70-79 Up ABCC4 ACTG2 ADAM33 ANKFY1 ATF4 ATP2B4 BAG2 BCHE BMP3 BRS3 BTC CAB39L CACNA1C CACNA1H CC2D2A CCDC69 CDK8 CHRM2 COL24A1 COMMD6 DCP1B DIP2C EML1 ENOX1 FOXF1 FOXP2 FXYD6 FZD7 GFRA1 GJC1 GLP2R GREM2 HAND1 HAND2 HOXA13 HOXB2 HOXB3 HOXB4 HOXD10 HOXD11 HOXD13 KCNH2 KCNMA1 KCNQ4 KIZ KLHL23 KLHL5 LIMS2 LRRC3 MAB21L2 MDM1 METTL24 MID1 MYH11 MYLK NKX2-3 NKX3-2 NME4 NPY4R NT5DC3 NTSR1 NXN PBX3 PDE9A PDZRN3 PDZRN4 PGM5 PHOX2B PLA2G2C PLEKHO1 PNCK PTGFRN PTGS1 PTTG2 RAB23 RAP1A RASSF3 RGS10 RNF150 ROR2 SEMA3A SMTN SPOP STON1 STON1-GTF2A1L SYDE2 SYNM TAB2 TACR2 TBC1D1 TGFB1I1 THAP8 TNFAIP8L1 TSPAN11 TSPAN2 XK ZEB1 ZNF219 ZNF232 ZNF511 Artery - Tibial Female 70-79 Up ACAN ACTA2 ACTN4 ADARB1 ADIRF AEBP1 AEBP2 AMIGO2 ANKRD37 ARHGEF17 ARHGEF39 ATL3 BCAM C11ORF96 CCDC3 CDH6 CHSY3 COL14A1 COL18A1 COMP CPED1 CRLF1 CRTAC1 CSPG4 CSRP2 CTAG1A DACT3 DSTN DSTNP4 DUXA ENOX2 FHL5 FOXC1 FOXC2 FOXL1 FRY FZD1 GADD45A GPC6 HAUS7 HDX HEY2 HTR1B ID2 IGFBP7 JAG1 JAK2 KCNA5 KCNAB1 KCNE4 KIAA1671 KLHL26 MCAM MSRB3 MUSTN1 MYO1D NOTCH3 NTF3 NTRK3 P2RX1 PCDHB7 PCSK5 PDE4C PGF PLS3 PPP1R3C PRDM16 PRKG1 RASL12 RBPMS RCAN2 RERGL RHOB RNF180 ROCK1 ROR1 SETBP1 SFRP2 SHOX2 SMAD7 SMIM10 SMURF1 SOST SPOPL STAC2 SYTL2 TASP1 TBX18 TBXA2R TMEM181 TMEM47 TRABD2B TSC22D1 UBA2 UGGT2 USP17L23 USP35 VPS13A WTIP ZFHX3 Cells - Cultured Fibroblasts Female 70-79 Up ABL2 ADAMTS6 ANXA2 ARHGAP11A ARSJ ASPM AURKA BIRC5 BMPER CALU CCBE1 CCNA2 CCNB1 CD109 CDC20 CDC6 CDCA7L CDK1 CENPA CENPE CENPF CENPI CEP55 CKAP2L CKAP4 CLSPN COL6A3 DCBLD2 DDIAS DEPDC1 DHFR DIAPH3 DLGAP5 DTYMK ECT2 EMC1 ERCC6L FANCB FGF5 FOXM1 GINS4 GNPNAT1 GTSE1 HAS2 HMGA2 HS3ST3A1 IGF2BP2 IKBIP IQGAP3 KIF14 KIF18B KIF20A KIF20B KIF23 KIF4A KPNA2 LMNB2 LOX LOXL2 MCM10 MELK MME NCAPG NCAPG2 NDC80 NECTIN3 NEIL3 NT5E POLE2 POMK PRC1 PRKDC PRR11 PRSS12 PSG5 PSG9 RACGAP1 RFX8 RNASEH2A RRM1 RRM2 SERPINE1 SHCBP1 SKA3 SMC4 SPC24 SPDL1 SSR3 STEAP1 STEAP1B TK1 TOP2A TPX2 TRIP13 TRNP1 TRPA1 TUBA1C TUBB UBE2C UHRF1 Brain - Nucleus Accumbens (Basal Ganglia) Female 70-79 Up AKAP5 ANKRD66 ARPP21 C10ORF105 C1ORF87 C2ORF50 C4ORF47 C4ORF50 C7ORF57 CACNA1E CACNG4 CAMKV CAPSL CCDC78 CDH9 CFAP157 CFAP47 CFAP52 CFAP54 CFAP73 CHAT CRB1 CSMD3 DLL3 DNAH2 DNAH7 DNAH9 DRD1 DRD3 DYDC2 EFCAB12 EFNB3 ENKUR FAM86B2 FOXJ1 FRMPD2 GABRA4 GABRA5 GABRB1 GABRG1 GAS2L2 GPR52 GPR6 HES5 HTR1D HTR2C IL5RA IMPG1 KCNA4 KCNK18 KCTD4 KIAA2012 LAMP5 LHFPL1 LRRC7 LRRC74B LYPD1 NCDN NEK11 NEK5 NKAIN4 NMBR NME9 NTSR2 NWD1 OR12D1 OR12D2 OR1E2 OTOF PDYN PLPPR1 POU3F4 PPIAL4G PRR29 PTPN5 PTRH1 RESP18 RGS20 RSPH1 SDR42E2 SHISA7 SIX3 SLC47A2 SNX32 SPAG17 SPAG8 SPEF1 STOML3 SV2C SYNPR TMEM158 TTLL9 TUBA4B VWA3A WDR49 WNT1 WNT10B ZBBX Brain - Cortex Female 70-79 Up ABHD8 ADGRA1 ADGRB1 ADGRB2 ALDH6A1 ALDOC ANKRD24 APC2 BAALC BHLHA9 BRINP2 BTBD2 C1QL2 C2CD4C CABLES1 CABP1 CACNG5 CAMK2A CCK CDH20 CDIP1 CHRM1 COL20A1 COL26A1 CRB1 CRB2 CRYGA CSAG1 CTNNA2 DBNDD1 DBX2 EIF4E1B ELFN2 ENHO FAM107A FAM163B FEZF2 FOXD4L6 FSD1 FXYD7 GABRG1 GALNT8 GPR37L1 GRIN1 GRM2 HEPACAM HHIPL1 ITPKA KCNH3 KCNN1 KCNS1 KIF1A KIF5A KIF5C LCN15 LHX2 LINGO1 LRFN2 LZTS1 MAPK8IP2 MCF2L2 MGAT5B MLC1 MRO NAGPA NANOS3 NCAN NGB NRGN OLFM1 PALM PLEKHM2 PNMA6A POU6F2 PRKAR1B RAPGEF4 RASL10A RIMS2 RLBP1 RNF208 RORB SCG3 SFXN5 SLC25A18 SLC39A12 SNCB SNPH SNX32 SOHLH1 STOX1 STX1A SYN1 TBR1 TESPA1 TSPOAP1 TTYH1 UNC13C UNC5A WNT7A ZDHHC22 Brain - Cerebellar Hemisphere Female 20-29 Up ADAM22 AKAIN1 ALS2 ARHGEF33 ATP6V1G2 BEND6 BSPH1 BTBD3 CA10 CA8 CACNB4 CADPS2 CALN1 CAMK4 CAMKK2 CBLN1 CBLN3 CDYL2 CHN2 CHRNA6 CNTN6 CPLX4 DIRAS2 DNM3 EN2 ETV1 FAM131B FGF20 FGF3 FSTL5 GABRA1 GABRA6 GCSAML GLCE GNG13 GPR137C GPR158 GRIA4 GRID2 GRIK2 GRM1 HTR5A KCNA1 KCND2 KCNJ3 KCNK1 KCTD8 KDM4C LGALS16 MKRN2OS NDRG3 NEUROD1 NREP NRXN3 PAK5 PCDHA6 PCDHA8 PCDHGC4 PCLO PKIB PLEKHD1 POLB PPP1R17 PRSS51 PSD3 PTPRR PVALB RAB37 RAB3IP RELN RIMS1 RIT2 SCN2A SH3GL2 SHF SLC1A6 SLC6A5 SMIM13 SNAP25 SOGA1 SPHKAP SRGAP2 SRGAP2B STMN2 STXBP5L SYT2 SYT4 SYT9 TIAM1 TMEM163 TMEM266 TRIM67 UBASH3B UNC13C VAX2 VWC2 ZBTB18 ZIC1 ZIC4 ZP2 Brain - Anterior Cingulate Cortex (BA24) Female 20-29 Up APC ASIC2 ATOH7 C11ORF87 C1ORF216 C1QL3 C2ORF80 C3ORF14 CALM1 CALM3 CAMK2N1 CREG2 DEAF1 DGKZ DLG2 DLX1 DOK6 DRD5 ELAVL2 ENC1 EPHA5 ERC2 FAM163B FAM81A FBXO41 FGF13 FREM3 GABRA3 GAD1 GAP43 GDA GNG3 GPR26 GRIK1 GRIN3A GSG1L2 HPCAL4 HRK HS3ST4 IDS KCNC2 KCNQ3 KCTD16 LIMK1 LMO4 MAP1A MAP2 MCHR2 MEIS3 MLLT11 MPPED1 MYO5A MYRIP NANOS3 NAP1L5 NAPB NEUROD6 NPTXR NRSN1 NXPH1 NXPH2 OLFM1 OR1L1 OSTN PACSIN1 PAK3 PDXP PFN2 PGM2L1 PHF24 PLPPR5 PPP4R4 PTER RAB3C RAB6B RAPGEF4 RGS4 RIMKLA RNF11 SERPINI1 SGTB SHANK1 SHC3 SLC17A7 SLC4A10 SMIM10L2A SMIM10L2B SMIM17 SNCA SNX10 STAU2 STMN2 STUM STX1A SYN2 TAGLN3 TTC9B VAMP2 WSB2 YWHAH Brain - Caudate (Basal Ganglia) Female 20-29 Up AASDHPPT ACTR3B ADORA2A AKAP5 AMBN ANKRD34B ANKS1B ANO3 ARPP19 ARPP21 ATP2B1 CACNA1E CACNA2D3 CACNB4 CALB1 CDH8 CDKL5 CHRM4 CLVS1 COCH DACH1 DCC DCX DGKB DGKH DGKI DLX6 DOCK4 DRD1 ELMOD1 ENTPD3 GABRA4 GAD2 GNAL GPR139 GPR149 GPR158 GPR52 GPR88 GRM3 HPCA HS3ST5 HTR2C HTR6 IMPG1 ITFG1 KCNAB1 KCNQ3 KLHL13 LRRC7 LRRN1 LRRTM2 LRRTM3 MCTP1 MINDY4B MZT1 NDST3 NETO1 NETO2 ONECUT2 PCDH10 PCP4 PCP4L1 PDE10A PDE1B PDE7B PDP1 PDYN PENK PHACTR1 PLCB1 PLPPR1 PLPPR4 PLSCR5 PPP1R1B PPP3CA PPP3R1 PRKCB PTPN5 RASD2 RGS7BP RGS8 RIC8B ROBO2 SCN4B SHISA9 SLC2A13 SLC35D3 SPINK9 ST8SIA3 STRIP2 SYNDIG1L SYNPR SYT16 SYTL5 TAC1 TCAF1 TMEFF1 TMEM196 TOMM70 Brain - Nucleus Accumbens (Basal Ganglia) Female 20-29 Up ABI2 ACTR3B AKAP5 ANKRD34B ANKRD63 ANKS1B ARHGEF9 ARPP21 C4ORF50 C6ORF141 CACNA1E CACNG4 CALB1 CAMKV CENPVL3 CRYM CSMD3 CT45A2 CT45A7 DACH2 DGKB DGKK DLX6 DRD1 DRD3 EFNB3 ELMOD1 FAT3 GABRA4 GABRA5 GABRB1 GAD2 GNAL GNG7 GPC5 GPR101 GPR149 GPR27 GPR52 GPR6 GRIN2B GRM3 HPCAL4 HS6ST2 HTR1D HTR2C HTR6 IMPG1 KCNA4 KCNIP1 KCNQ3 KCTD4 KHDRBS2 KNCN LAMP5 LHFPL1 LINGO3 LRRC7 LRRTM3 LZTS1 MAGEL2 MINDY4B MMD MZT1 NAT16 NCDN NECAB2 NNAT OPRK1 OTOF PCDHGC5 PCP4L1 PDE7B PDYN PEG10 PENK PHACTR1 PLPPR1 PLPPR4 PLPPR5 POU3F4 PPP4R4 PTPN5 RAB40B RFK RGS20 RGS8 SH2D5 SHISA9 SLC32A1 SLC35D3 SORCS3 SOWAHA SOX1 SP9 ST8SIA3 SYNPR TMEM158 VSTM2A WNT1 Liver Female 20-29 Up A1BG A1CF ABCG5 ABCG8 ACAA1 ACOT12 ACOX2 ADH4 ADH6 AGT AGXT AHSG AKR1D1 ALB ALDH8A1 AMBP APOA1 APOA2 APOC1 APOC2 APOC3 APOC4 APOM ASGR1 ASGR2 ATF5 C8A C8B C8G CCL16 CFB CFHR2 CLEC4M CYP1A2 CYP2C19 CYP2C8 CYP2C9 CYP2D6 CYP3A7 CYP3A7-CYP3A51P CYP4A11 CYP4A22 DMGDH DPYS EPO F12 F13B F2 F7 FCN2 FGF23 FGL1 FMO3 GBP7 GCGR GCKR GLTPD2 GLYAT HAAO HABP2 HMGCS2 ITIH1 ITIH3 ITIH4 KLKB1 KMO KNG1 LPA MASP2 NAT2 NPC1L1 NR1I3 OIT3 ORM1 PGLYRP2 PIPOX PLG PROC PROZ RBP4 RDH16 RTP3 SERPINA1 SERPINA11 SERPINA6 SERPINC1 SERPIND1 SERPINF2 SHBG SLC10A1 SLC22A7 SLC27A5 SLC38A3 SMLR1 SPP2 TFR2 TM4SF4 TM4SF5 TTC36 VTN Brain - Cortex Female 20-29 Up ADCY1 ADGRB2 AGBL4 APC ATCAY ATRNL1 B3GAT1 BEAN1 BRINP2 BRSK1 C11ORF87 C2CD4C CABP1 CACNG3 CAMK2A CAMK2N1 CBLN2 CCK CHRNB2 CNTNAP5 COL20A1 COL26A1 CREG2 CUX2 DAGLA DBNDD1 DGKZ DLG2 DOK6 ENC1 FAM163B FBXO41 FREM3 FRMPD4 GABBR2 GALNT8 GPR26 GRIN2A GTDC1 HECW1 HPCAL4 HS6ST3 HTR2A HTR3B IQSEC1 KCNC2 KCNH3 KCNH5 KCNIP3 KCNQ3 KCNS1 KCNV1 KCTD16 KIAA1549L KIF21B KIF3C KIF5C LCN15 LINGO1 LRRTM4 LYNX1 MAP2 MCHR2 MGAT5B MPPED1 NCALD NLK NPTXR NRSN1 OLFM1 OPRD1 OR14I1 PACSIN1 PHF24 PPP1R16B PPP2R2C PPP4R4 R3HDM1 RAB11FIP4 RAB6B RAPGEF4 RASGRF2 RGS4 RIMKLA RIMS3 RIMS4 RPH3A SHC3 SLC17A7 SLITRK1 SOHLH1 SPRN STUM STX1A SVOP TESPA1 TMEM132D TPPP TSPOAP1 WSB2 Pituitary Female 20-29 Up AHI1 AIPL1 ARC ARHGAP36 ASCL1 ASIC4 BAIAP3 C14ORF39 C21ORF58 C21ORF62 C2ORF15 CDRT4 CFAP47 CGA CHGB CHST8 CNGA3 COL22A1 COL9A2 CRHR2 CSH2 CSHL1 CUL7 CXXC4 DEFB135 DGKK DMRTC1B FBXO16 FICD FOXO6 GAGE10 GALR1 GCK GDF5 GH1 GHSR GJB7 GNB3 GNRHR GPR50 GPR61 GPR68 HTATSF1 IGSF1 INSM1 IQCJ KSR2 LHB LHX3 MDK MSI1 MYO15A MYO16 NAALAD2 NEUROD4 NNAT NTS NXF2B OR10G3 OR13C2 OR13C9 OSTCP2 PCDH15 PCDHB1 PCSK1N PHF21B PLD3 POMC POU1F1 PRL PRLHR PROP1 RAB36 RAB3B RAX RAX2 REC8 RIIAD1 RNF224 SCG5 SIX3 SIX6 TAC4 TBX19 TCP11X1 TCP11X2 TGFBR3L TMEM244 TPH2 TRHR UGT2A1 UGT2A2 UNC79 VWA3A VWA5B1 VWA7 ZBTB8B ZFR2 ZNF10 ZP1 Brain - Amygdala Female 40-49 Up ACBD7 ADCY8 AGAP1 AK5 ALDH7A1 AMZ1 APC AQP4 ATOH7 ATP6V1H B3GAT1 BCAN BRINP2 CAMK2A CAMK2N1 CDH20 CDH4 CDH9 CPE CPLX2 CPNE6 CSPG5 CT45A2 CT45A7 CTNNA2 CTNND2 DCLK2 DCSTAMP DEAF1 DOK6 ELFN2 ENC1 EPHA5 ERC2 ETNPPL FAM171B FBXO2 GABRA2 GAREM2 GNG2 GPM6A GRIA1 HEPACAM HPCAL4 HSD11B1L IDS KCNH3 KCNK4 KCNN1 KCTD4 LHX2 MAPK3 MAPK8IP2 MEIS3 MMD MT3 MYRIP NCAM2 NCAN NCS1 NECAB2 NKAIN4 NPAS3 NPTXR NR2E1 NRG3 NTRK2 OCM OPRK1 PACSIN1 PALM PLPPR4 PTPRZ1 RAPGEF4 RASL10A RTP5 SCD5 SHANK1 SLC17A7 SLC18B1 SLC1A2 SLC1A3 SLC30A3 SLC38A8 SMOX SOX2 STON2 STOX1 STUM SYN2 SYTL5 TFAP2D TFPT TNR TSPOAP1 TTC9B TTYH1 UCMA UNC13C YWHAH Ovary Female 70-79 Up ACSM3 ADAMTS1 ADRB3 AMHR2 ANGPTL5 ARX ASIP BAMBI BNC2 BST2 C21ORF62 CCNB1IP1 CD22 CDH23 CDK15 CHST7 CLCN5 CLSTN2 CPZ CRYGD DET1 ECEL1 EIF3L EML5 FFAR1 FOXL2 FOXL2NB FPGS GALNT10 GATA6 GREB1 GSTM5 HNRNPA1 HOXC5 HOXD4 HS3ST1 IGFBP5 IGSF10 INHA KLHDC8A LAG3 LEFTY2 LHX9 LPAR4 MCC MDK METAP1D MEX3A MMP21 MMP23B MOB3B NFATC4 NINL NRK NXPH2 OBSL1 PBX3 PEG3 PHF6 PLXDC1 PROK1 RASL11B RBP1 ROBO3 RPL23A RPL24 RPL31 RPL35A RPL5 RPS20 RPS25 RPS27 RPS3 RPS4X RPS8 SGCZ SIGLEC11 SIGLEC16 SIMC1 SLC4A3 SNCAIP ST13 SULF2 SYTL4 TCEAL9 TENM4 TMEM221 TMEM98 TSHZ3 TTC8 UBXN8 VLDLR WFIKKN2 WIPF3 ZMYM3 ZNF431 ZNF471 ZNF556 ZNF66 ZNF665 Vagina Female 70-79 Up AADACL4 ADAM33 ADAMTSL5 ADGRG4 ALOX12 AR BDKRB2 BMP4 C17ORF67 CGNL1 COG5 COL16A1 CRCT1 CYP27C1 DIO3 EDN2 EDN3 EPB41L4A ESR1 EVX1 FBLN1 FGF10 FLT3LG FRRS1 FUT5 GABRE GDF7 GJE1 GLIS1 GOLGA6L9 GP6 GPR142 GSTM2 HCG22 HOXA13 HOXD10 HOXD11 HOXD12 HOXD13 HOXD3 HOXD9 HP1BP3 HPGD HPSE2 HSD17B1 IER5L IGDCC4 ISL1 KLK12 LCE3D LPAR6 LRFN5 LRP6 MASP1 MATN1 MATN2 MICA MRGPRE MSGN1 NBL1 NFATC4 NXNL2 OFD1 OR2A14 OSR2 PABPC4L PAMR1 PI16 PRLR PRSS12 RAD52 RNF223 RSPO1 SALL3 SFRP1 SMO SOX7 SPAG11B SPEF2 SPINK5 SPINK7 SPON2 SUMO4 SUPT20HL1 TBC1D3 TBX6 TMEM200B TMPRSS11A TMPRSS11D TMPRSS11E TTLL3 VIPR2 VSIG10L WDR27 WNT2B ZNF232 ZNF558 ZNF630 ZNF808 ZNF83 Spleen Male 70-79 Up ADM5 AIF1 ANKDD1A BTN3A1 BTN3A2 C1QA C1QB C8ORF58 CABP4 CARD9 CCL14 CCM2L CD5L CD72 CDCP2 CETP CNKSR3 CPLX3 CSAG2 CSF1R CXCL1 CXCL13 CXCL6 DNASE1L3 EMID1 EXOC3L1 FAM153A FAM43A FAM72A FAM9C FCGR3A FCRL3 FES FHOD1 FLI1 GDPD2 GDPD5 GIPC2 GPR182 GSDMD HLA-F HMOX1 HOMER3 HYAL1 HYAL2 IL18BP IL2RA INSR ITGAD KAZALD1 KAZN LILRB1 LILRB5 LPCAT1 LRTM1 MS4A7 NOS3 NPY1R NR5A1 NTN4 OR2AJ1 OR52N4 OR5AK2 OR9G4 P2RX5 P2RY6 P3H2 PCDH17 PCSK6 PDE2A PDE6G PDLIM2 PEAK1 PITPNM3 PLEKHG1 PPM1N PRR5 PRR5L PSTPIP2 PTGER1 RENBP RNASE13 ROBO4 SCN11A SEMA3D SIGLEC12 SLC9A5 SPIC STAB1 STAB2 TDGF1 TLX1 TMC8 TMEM26 TNFAIP1 TNFRSF4 TNFRSF6B TRAPPC3L VCAM1 ZNF160 Brain - Hippocampus Male 30-39 Up ACBD7 ADCY1 AGAP1 AGAP2 APBA1 APC ARHGAP11B ATOH7 B3GAT1 BEAN1 C2ORF80 CACNG3 CAMK2A CAMK2N1 CASKIN1 CBLN4 CBX6 CNTN5 CNTNAP5 CPLX2 CTNNA2 CTNND2 DDN DEAF1 DGKZ DLG2 DLG4 DLGAP3 DOK6 ELFN2 ENC1 EPHA5 ERC2 FBXO41 FEZF2 FGF13 FXYD7 GNG3 GRIK1 GRIN3A HPCAL4 HS3ST4 HS6ST3 HSD11B1L HTR1A IDS JPH3 KCNH3 KCNN1 KIF21B KIF5A KIF5C LHX2 LIMK1 LINGO1 MAP1A MAP2 MAP3K10 MEIS3 MYRIP NANOS3 NCS1 NECAB2 NPSR1 NPTXR NSMF OLFM1 OTOL1 PACSIN1 PALM PCDH11Y PDXP PDZD4 PGM2L1 PHACTR3 PHF24 PLPPR3 PLPPR5 PPP1R9B PPP4R4 RAB11FIP4 RAB6B RAPGEF4 RGS21 RIMS4 SEMA6B SHANK1 SHANK2 SHC3 SLC17A7 SMIM10L2A SMIM10L2B SNPH SOWAHA STUM TFPT TSPOAP1 TTC9B VWC2L WSB2 Brain - Anterior Cingulate Cortex (BA24) Male 30-39 Up ARHGAP11B BEX5 BHLHA9 C1ORF216 C1QL3 C2ORF80 CA11 CABP1 CALM1 CALM3 CAMK2A CAMK2N1 CBLN2 CCDC85A CCK CHN1 COPS9 CREG2 CSPG5 CT45A2 CT45A7 CTNNA2 DLGAP1 DLX1 DOK6 DPF1 EIF4E1B ENC1 ERC2 FAM163B FAM171B FAM81A FDX2 FGF13 FXYD7 GABRA2 GAD1 GAP43 GDAP1L1 GNG3 GPM6A GPR26 GRIN3A HPCAL4 HSD11B1L HTR1A IDS KCNC2 KCTD16 LAGE3 LHX2 LIX1 LMO4 LRRC3B MAP2 MAPK10 MPPED1 MT3 NANOS3 NKAIN3 NOX3 NPM2 NPTXR NR2E1 NRG3 NRSN1 NXPH2 OLFM1 P2RY12 PACSIN1 PDXP PDZD4 PFN2 PHF24 PIN1 PPP4R4 PRKCB PRSS35 RAB6B RAPGEF4 RGS4 RNF182 SCG3 SERF1A SERPINI1 SHC3 SLC39A12 SSTR4 STK32C SYN2 TAGLN3 TFPT TMEM132D TTC9B USP17L15 VAMP2 VSNL1 VSTM2A WSB2 YWHAH Brain - Caudate (Basal Ganglia) Male 30-39 Up ADORA2A AMBN ANKRD34B ANO3 ARPP19 ARPP21 ATP2B1 BCR C1QTNF4 CACNG4 CDH8 CHAT CHRM4 CORT CPLX1 CTXN1 CYP46A1 DACH1 DACT2 DGKB DLX6 DRD1 ENTPD3 EYA1 FAM171A1 FBXL16 FKBP1B GAD2 GNAL GNG7 GPR139 GPR6 GPR88 GRM3 GSG1L HAGHL HCN2 HPCA HS3ST5 HSPBP1 HTR6 ITPKA JAKMIP1 KCNAB1 KCNF1 KCNH4 KCTD17 KLF16 LAMP5 LINGO3 LRP3 LRRC10B LRRN1 LRTM2 MC4R METRN NCDN NECAB2 NETO1 NGEF NRGN ONECUT2 OTOF PCP4 PCP4L1 PDE10A PDE1B PDE7B PENK PLCB1 PLPPR1 PLSCR5 PPP1R1B PPP2R2B PPP3CA PRKCB PRMT8 PTPN5 RAB40B RASD2 RGS14 RGS7BP RGS8 RGS9 RIC8B ROBO2 SCN4B SLC24A2 SLC25A23 SLC35D3 SP9 SPEF1 ST8SIA3 SYNDIG1L TAC1 TMEM158 UROS VAX1 ZMAT4 ZNF883 Brain - Nucleus Accumbens (Basal Ganglia) Male 30-39 Up ABI2 ACTR3B AKAP5 ANKRD34B ANKRD63 ANKS1B ANO3 ARHGEF9 ARPP21 C4ORF50 CACNA1E CACNA2D3 CACNG4 CALB1 CAMKV CHRM4 CLVS1 CNTNAP5 COCH CRYM CSMD3 CYP46A1 DACH2 DCC DGKB DLX6 DRD1 DRD3 EFNB3 ELMOD1 FAT3 FRMPD4 FRRS1L GABRA4 GABRA5 GABRB1 GABRB3 GAD2 GALNTL6 GNAL GPR101 GPR139 GPR149 GPR52 GPR6 GRIN2B GRM5 HS6ST2 HTR1D HTR2C HTR4 HTR6 IMPG1 JAKMIP1 KCNA4 KCNQ3 KCTD4 KIRREL3 LAMP5 LHFPL3 LINGO3 LRRC7 LRRTM3 MAPK1 MINDY4B NCDN NETO1 OPRK1 OTOF PCDH10 PCDH11X PCDHGC5 PCP4L1 PDE1B PDE7B PDYN PENK PHACTR1 PLPPR1 PLPPR4 POU3F4 PPP4R4 PTPN5 PTPRO RGS8 SH2D5 SHISA9 SLC32A1 SLC35D3 SLC9A7 SOWAHA ST8SIA3 STRIP2 SV2C SYNPR SYT16 SYTL5 VAX1 VSTM2A WNT1 Brain - Putamen (Basal Ganglia) Male 30-39 Up ADORA2A AMBN ANKRD34B ANO3 AP1S1 ARHGAP11B ARPP19 ARPP21 ATP2B1 BCR C6ORF141 CACNG4 CALB1 CDH8 CHAT CHRM4 COCH CORT CTXN1 CYP46A1 DACT2 DGKB DLX6 DRD1 DRD2 ENTPD3 EYA1 FBXL16 FKBP1B GAD2 GBX2 GNAL GNG7 GPR139 GPR149 GPR52 GPR6 GPR88 GRM3 GSG1L HCN2 HPCA HS3ST5 HTR1D HTR6 JAKMIP1 KCNAB1 KCNF1 KCNH4 KCNQ3 KCTD1 KCTD17 KLF16 LINGO3 LRP3 LRRC10B LRRN1 LRRTM1 LRRTM3 LRTM2 MINDY4B NCDN NETO1 NGEF NRGN ONECUT2 PCP4 PCP4L1 PDE10A PDE1B PENK PHACTR1 PLCB1 PLPPR1 PLSCR5 PPP1R1B PPP3CA PRKCB PTPN5 RASD2 RESP18 RGS14 RGS7BP RGS8 RGS9 RIC8B ROBO2 SCN4B SIX3 SLC25A23 SLC35D3 SOWAHA SP9 SPEF1 ST8SIA3 SYNDIG1L TAC1 TMEM158 VAX1 ZNF883 Kidney - Cortex Male 70-79 Up ACMSD ACY3 AQP2 AQP6 ATP6V0A4 ATP6V0D2 ATP6V1B1 ATP6V1G3 BBOX1 BSND C11ORF54 CDH16 CDH6 CLCNKB CLDN2 CLEC18A CLEC18B CLEC18C CUBN CYP24A1 CYS1 DCDC2 DDC DEFB1 DMRT2 EMX1 FCAMR FMO1 FOXI1 FXYD2 GALNT14 GDF15 GGT1 HAVCR1 HNF1B HOGA1 IL17RB KCNJ1 KCP KIF12 KL LRP2 LYG1 MIOX MT1H NAT8 NPHS1 NPHS2 NYX OR2T10 OR2T35 PAX2 PDZK1 PDZK1IP1 PKHD1 PODXL PRODH2 PTH1R PTH2R PTPRO RBP5 REN RHBG RNF183 SLC12A3 SLC13A1 SLC13A3 SLC16A4 SLC17A1 SLC17A3 SLC22A11 SLC22A12 SLC22A13 SLC22A2 SLC22A24 SLC22A6 SLC22A8 SLC23A3 SLC2A9 SLC34A1 SLC3A1 SLC47A2 SLC4A9 SLC5A10 SLC5A12 SLC5A2 SLC6A13 SLC6A18 SLC7A13 SMIM24 SPP1 TINAG TMEM174 TMEM213 TMEM252 TMEM52B TMEM72 UGT1A9 UGT2B7 UGT3A1 Brain - Cerebellum Female 30-39 Up ADAM11 ADAM22 ALS2 AMER3 ANKRD6 ARHGEF33 BLACAT1 CACNA1A CACNA1G CARMIL3 CBLN1 CBLN3 CCDC175 CECR2 CHD7 CKMT1B CLK4 CLVS2 CNPY1 COL27A1 CPLX4 DHDDS DISP2 EN2 EPB41 ERVV-1 FAT2 FGF3 FLT3 GLCE GPR137C GRID2 GRID2IP GRIK2 GRIN2C GRM1 GRM4 KCNAB3 KCNC1 KCND1 KCNK9 KCNT1 KLHL3 LCN8 LDLRAP1 LHX1 MAP1LC3B2 MDGA1 MEGF11 MMP24 MTBP MTCL1 NREP OR1F1 OTX2 PAX6 PCLO PLEKHD1 PPFIA4 PPIP5K1 PRSS51 PVALB RAB37 RASGEF1C RNF112 RUFY2 SCN2A SHF SKOR1 SLC22A31 SLC35F4 SLC6A7 SOGA1 SPIN2A SRGAP2 SRGAP2B SRRM3 SRRM4 SSTR4 STRC STXBP5L TAS2R14 TENM1 TFAP2E TMEM120B TMEM266 TRANK1 TRIM11 TRIM67 TRIM9 WSCD2 XKR7 ZFYVE28 ZIC3 ZIC4 ZIC5 ZNF337 ZNF382 ZNF493 ZP2 Minor Salivary Gland Female 50-59 Up AGFG2 ALDH1A3 ALX1 AMTN ANKRD36C APCDD1L AQP5 ASCL3 ATP6V1B1 AZGP1 BPIFB2 C6ORF58 CBR3 CCDC160 CCL28 CEACAM6 CHPT1 CHST9 CLDN17 CLDN24 CLDN8 CRACR2A CRACR2B CREB3L1 CRISP3 DEFB1 EHF ELF5 ENPP3 ENTPD3 FAM177B FAM3D FBN3 FDCSP FOLR1 FUT2 GALE GALNT3 GALNT4 GALNT5 GALNT6 GALNT7 GLYATL2 GOLM1 GPRC6A IGFL1 IRX1 IRX2 KCNN4 KRT19 KRT7 LHX8 LPO LRRC26 LRRC31 LTF LYZ MLPH MMP7 MSGN1 MUC16 MUC19 MUC5B MUC7 NAALADL2 NKX2-6 NXPE2 ODAM OTX1 PANX3 PAX3 PIGR PIP PLEKHS1 PLPP2 PROM1 PRR4 RAD51B RUNX1 SCGB2A1 SCNN1A SH3BP4 SLC4A11 SLC6A14 SLITRK6 SLPI SOX9 SPDEF SPINK6 STATH TCN1 TFCP2L1 TMED3 TMEM63A TOX3 TRPV4 VGLL1 WFDC2 ZG16B ZNF552 Adrenal Gland Male 70-79 Up AADAC ABCB1 ABCC3 ABCF3 AKR1B1 ALAS1 AMHR2 APOE AQP11 AS3MT ASB4 C2CD2 CELA1 CREBL2 CTSA CYB5B CYP11A1 CYP11B1 CYP17A1 CYP21A2 CYP2W1 DEXI DHCR24 DLK1 DUSP16 EBP EPHX1 FADS2 FAM166B FDPS FDX1 FDXR FGF11 FNDC4 GALM GNPTG GSTA1 GSTA3 GSTA4 HDHD3 HOXA5 HSD3B2 HSPD1 HSPE1 IDI1 IFITM10 KCNJ5 KCNK3 KCNN2 KCNQ1 KLHDC8B LBHD1 LONP1 MAP3K15 MC2R MCOLN3 MGARP MMAB MOB4 MRAP MYO7A NBPF1 NR4A2 NR5A1 NUP62CL PABPN1L PEBP1 PLBD2 PORCN PPIF QPCT QPRT RARRES2 RBBP7 RBKS RGN RMDN2 SAT2 SCAP SCARB1 SEMA3B SIAH2 SLC16A9 SLC23A2 SLC26A1 SLC47A1 SLC8B1 SOAT1 SREBF1 STAR TBX3 TKFC TM7SF2 TRAPPC2L WHRN ZBTB21 ZNF275 ZNF280A ZNF616 ZNF836 Pancreas Male 70-79 Up AKR7A3 AMY1C AQP12A AQP12B ASCL5 BHLHA15 BNIP3 C2CD4B CATSPERB CCNO CEL CELA2A CELA2B CELA3A CELA3B CFC1 CFTR CLPS COMTD1 CPA1 CPA2 CPB1 CTRB1 CTRB2 CTRC CTRL CUZD1 CXCL2 EPB41L4B ERO1B ERP27 F3 FAM3B FKBP11 FSCN2 FUT1 GCG GOLGA8B GP2 GPR150 IFITM5 IL22RA1 IL32 INS KCNK16 KIRREL2 KLK1 KSR1 LENG9 LHFPL5 LMF2 MAP3K21 MNX1 NR5A2 OR10G4 OR9I1 P4HB PDCD4 PDIA2 PDX1 PGGHG PLA2G1B PLEKHH3 PLIN5 PNLIP PNLIPRP1 PNLIPRP2 POU5F1 PPP2R2D PRSS1 PRSS2 PTF1A RBM20 RBPJL REG1A REG1B REG3A SCGB1C1 SCTR SERPINA3 SERPINI2 SLC30A8 SLC38A5 SLC39A5 SLC43A1 SPINK1 SRPRA SST ST6GALNAC4 SYCN TBC1D30 TC2N TECPR1 TMEM52 TPRN TRPV6 TUBG2 UNC5CL XBP1 ZNF710 Liver Female 30-39 Up ABCB11 ABCB4 ABCC2 ABCG8 ACAA2 ACOT12 ACSM2B AFM AGMO AGT AKR1C4 AKR1D1 ALB ALDH8A1 ANG APOA5 APOB APOH C4BPA C5 C6 C9 CES1 CFHR1 CFHR2 CFHR4 CFHR5 CFI CLEC1B CPB2 CYP2A6 CYP2A7 CYP2B6 CYP2C18 CYP2C19 CYP2C8 CYP2C9 CYP2E1 CYP3A4 CYP3A43 CYP3A7 CYP3A7-CYP3A51P CYP8B1 DPYS EHHADH F11 F13B F5 F9 FGA FGB FGG FGL1 GC GLTPD2 GLYATL1 HABP2 HAO1 HAO2 HP HSD17B6 INHBC ITIH2 KNG1 LPA MAT1A NAT2 NPC1L1 NUGGC ORM1 PIPOX PLG PON1 PTGR1 PZP RBP4 SAA4 SCP2 SERPINA10 SERPINA7 SERPINC1 SHMT1 SLC10A1 SLC16A13 SLC22A9 SLC27A2 SLC2A2 SLCO1B1 SMLR1 SPP2 SULT2A1 TDO2 TM4SF4 TM4SF5 TTPA UGT1A1 UGT1A3 UGT1A4 UGT1A6 UGT2B4 Fallopian Tube Female 50-59 Up ADAMTS3 ADGRG4 ALX1 ANKRD66 ATP8B4 BCL9 BNC2 BOC C10ORF95 C11ORF16 C20ORF85 C2ORF50 CAPS CAPSL CCDC17 CCDC78 CCDC81 CDHR3 CDHR4 CFAP100 CFAP157 CFAP47 CFAP73 CROCC2 DCDC2B DEFB115 DLEC1 DNAJB13 DRC3 DYDC2 EMX2 ESR1 FOXJ1 FRMD7 GAS2L2 GATA2 GATA5 GMNC GRIN3B GUCY1A2 HOXA3 HOXA5 HOXA6 HOXC4 HOXC5 HOXC6 HOXD3 HOXD4 KCNRG KIAA2012 LDLRAD1 LIMS4 LONRF2 MAMDC2 MAPK15 NEK5 NFASC NHLRC4 NPIPA7 NUTF2P4 NXNL2 ODF3B OR1M1 OR2V1 OR2V2 OR5A2 OR5W2 OR6C76 OR7G1 OSR2 OVGP1 PLXDC1 PRR29 PRSS33 PTRH1 RAI2 RERG RP1 RSPH4A RSPO1 SAXO2 SERTM1 SETMAR SLC24A3 SLITRK3 SNTN SPEF2 SUPT20HL1 SUPT20HL2 TCEAL1 TCF23 TMEM212 TMEM231 TRANK1 TUBA4B VWA3A WDR38 WT1 ZCCHC12 ZNF516 Bladder Male 40-49 Up ABCC4 ACER2 ADGRG4 ADRB3 CHRM3 CLEC3A DEFB103A DHRS2 EVX1 GATA5 GLP2R HOXA1 HOXA13 LSM11 NCKAP1L OR10H1 OSBPL10 P2RX1 P2RY14 PADI3 PEX14 PGM5 PITX2 PLA2G4A POU5F1 PRDM6 PTGIS PTGS1 RBMY1J SCN11A SCUBE2 SLC2A8 SLITRK6 SNX31 TMEM252 UGT1A8 UPK1A UPK1B UPK2 UPK3A VGLL1 WFDC10B WFDC13 ZNF552 ZNF888 Cervix - Ectocervix Female 40-49 Up ADAM33 ADAMTS19 ADAMTSL5 ADGRA2 ADRA1D ADRA2A ALDH1A2 AR C1QTNF5 CACNA1G CDKL1 CGNL1 CHD3 CNPY4 COL16A1 COL27A1 COL5A1 COLEC12 CPXM1 CTSK CXCL12 CYP27C1 DDAH2 DEFB106A EDNRA ELFN1 EMX2 ESR1 F10 FBLN1 FOXL2NB GDF7 GPNMB GUCY1A2 GUCY2F HOXA10 HOXA11 HOXA13 HOXD12 HOXD13 IGDCC4 IGFBP5 IL17RB ISLR ISOC1 JAZF1 KLHL13 LRFN5 LRP6 LRRC17 MAS1 MASP1 MATN1 MATN2 MDK MEIS1 MFAP2 MITF MSX1 NBL1 NFATC4 NR2F1 NXNL2 OLFML2A OR5B3 OR5L1 OR8H1 OSR2 PAMR1 PBX1 PGR PHF21B PLPP3 PMEL PMEPA1 PRLR PRSS12 PTPRU REM1 RSPO1 SFRP1 SFRP4 SH3PXD2A SH3PXD2B SLC18A2 SMO SMPDL3A SNCAIP SP5 SPEF2 SPON2 STRA6 SULF2 TCF12 TMEM200B TRHDE TTLL3 TYW1 ZBTB12 ZNF516 Cervix - Endocervix Female 40-49 Up ADAM33 ADAMTS19 ADAMTSL5 ADGRA2 ADRA2C ALDH1A2 AR C17ORF58 C1QTNF6 CDKL1 COL16A1 COL27A1 COL3A1 COL5A1 COLEC12 CPXM1 DCHS1 DIO3 EDNRA ELFN1 EMX2 EPHB4 ESR1 FAM20A FBLN1 FOXL2 FOXL2NB GDF7 GUCY1A2 HOXA10 HOXA11 HOXA13 HOXD10 HOXD11 HOXD9 IGFBP5 IL17RB ISLR ISOC1 KCNG1 KIF26A KLHL13 LAMC3 LEFTY2 LRFN5 MASP1 MATN1 MATN2 MDK MEX3A MFAP2 MITF MMP11 MSX1 MUC16 NBL1 NFATC4 NXNL2 OR10AC1 OR4C15 OSR2 PAEP PAMR1 PBX1 PGR PKD1L2 PLEKHS1 PMEPA1 PRLR PTK7 PTPRU REM1 RGPD2 RPRM RSPO1 SALL1 SCGB1D4 SCGB2A1 SCUBE2 SERTM1 SFRP1 SFRP4 SMO SNCAIP SOX4 SP5 SPEF2 SPON2 STRA6 STX18 SULF2 THSD4 TMEM200B TSHZ3 WDR86 WFDC2 WNT2 XKR5 ZNF516 ZNF704 Bladder Male 50-59 Up ABCC4 ACER2 ADAM33 ADGRD1 ATF4 BAG2 BAMBI BDKRB2 BMP4 BMP5 BTBD16 C16ORF74 CCL7 CLEC3A COL16A1 CTU1 CYGB DCP1B DHRS2 DHX35 DNAJC1 EDAR FBLN1 FBXL22 FOXF1 GATA5 GLP2R GSTM1 HOXA1 HOXA13 HS1BP3 HSD17B2 IL2 LAT LSM11 MATN2 MICAL1 MS4A2 MSX2 NME4 NR2C2AP OR10H1 OR13A1 OR13C4 OR1L1 OR4X1 OR5M11 OSBPL10 P2RX1 P4HA3 PADI3 PDCL3 PDPN PEX14 PGM5 PI16 PITX2 PKIG PLA2G4A PLAT POU5F1 POU6F2 PRDM6 PTGS1 PYGB RRP8 S100P SAMD11 SEMA3E SERPINE2 SHROOM1 SLC14A1 SLC2A8 SLC2A9 SLITRK6 SNX31 SPON1 STON1-GTF2A1L SYT8 TACR3 THAP8 TIMP1 TPST1 TRIM47 TRMT61A TRPA1 TSLP UGT1A6 UPK1A UPK1B UPK2 UPK3A USP17L8 VGLL1 VPS72 WFDC1 WFDC10B WFDC13 ZNF552 ZNF888 Brain - Substantia Nigra Male 20-29 Up ADARB2 ADORA1 AGPAT4 AMZ1 ANKRD40 AP1AR ASAH2 ASPHD1 BCAS1 BHLHE41 CERCAM CHRNA6 CHRNB3 CLEC19A CLEC9A CNDP1 CNP CNTN2 COL20A1 COL9A2 COX6A1 CSF1R CX3CR1 DBNDD2 DBX2 DNAJC6 DNER DOK6 DSCAM DYNC1LI2 EML2 ERVV-2 FEZ1 FGF1 FOXB1 GALNTL6 GJC2 GLRA1 GPR26 GSG1L HCN2 HIPK2 KCNE5 KCNG4 KCNJ6 KCNK10 KLHL1 LDLRAD4 LGALS13 LHFPL3 LRRC55 LUZP2 MAG MAP4K4 MBP MMD MOG MTURN MYRF NEFL NIPA1 NIPAL3 NKX6-2 OLIG1 OLIG2 OLR1 P2RY12 PAIP2B PAQR6 PCDH11Y PCDH15 PIRT PKP4 PLD4 PLEKHB1 PLP1 PLPP4 QDPR RET RND2 RPE65 SHTN1 SLC10A4 SLC18A2 SLC5A11 SLC6A11 SLC6A3 SOGA3 SPOCK3 SPP1 SPX TMEM144 TMEM255A TMEM88B TNR TP53INP2 TREM2 TRIM41 TTYH2 TUB Brain - Amygdala Male 20-29 Up ACBD7 ADCY8 AGAP1 ALDH7A1 AMZ1 APC AQP4 B3GAT1 B3GAT2 BAALC BCAN BEX5 C1ORF216 C2CD4C C2ORF50 CAMK2N1 CCK CFAP161 CHST6 COL20A1 CPLX2 CSPG5 CTNNA2 CTNND2 DCX DEAF1 DLG2 DOK5 DOK6 ELFN2 EPHA5 ERC2 FAM181B FBXO2 FRMPD2 GABRA2 GAP43 GNG3 GNG4 GPC5 GPM6A HEPACAM HHIPL1 HPCAL4 HSD11B1L IDS KCNK10 KCNN1 KCNQ3 KIF1A KIF21B KIF5C LHFPL3 LHX2 LMO2 LRRC3B MAP1A MAP2 MEIS3 MLC1 NANOS3 NCAN NCS1 NKAIN3 NKAIN4 NPTXR NR2E1 NRG3 NTRK2 OR7G3 P2RY12 PACSIN1 PCDHGC3 PEA15 PHACTR3 PPP4R4 PSD2 PTPRZ1 RAPGEF4 RASL10A SEMA6B SFXN5 SHANK1 SLC17A7 SLC1A2 SLC6A1 STK32C STUM SYN2 TFAP2D TNR TP53BP2 TSPOAP1 TTC9B UCMA UNC13C WNT7A WSB2 YWHAH ZNF474 Brain - Hypothalamus Male 20-29 Up ACHE AGBL4 AIRE ANKRD34C ASIC2 ATP1A3 AVP B4GAT1 BEX5 BHLHA9 CALY CAMK2N2 CBLN4 CCDC184 CD200 CNDP1 CRH CSMD2 DCLK1 DNAJC6 DNER DSCAM EIF4E1B ELAVL4 EPHA5 FEZF1 FNDC9 GABRA3 GABRG2 GABRG3 GALP GLRB GPR45 GRM7 HAP1 HAPLN4 HCRTR1 IFNA16 INA INPP5F INSM2 KCNK10 KCNS2 LGI3 LHX5 LRFN5 LRRC55 MAGEL2 MCHR1 MLLT11 MOAP1 NAP1L5 NEFL NEFM NELL1 NELL2 NGB OR14I1 OR5D3P OTP OXT P2RY12 PABPC1L2A PABPC1L2B PCSK1 PIRT PLPP4 PNMA2 PNMA3 PPFIA2 RAB6B RTL1 SCG2 SCGN SCN1A SCRT2 SLC17A6 SLC4A10 SMIM10L2B SMIM17 SULT4A1 SYP TCEAL7 TMEM130 TMEM132D TMEM196 TPPP TRH TRPC5 TUBB3 UCHL1 UCN3 VAMP1 VAX1 VSNL1 VSTM2A VSTM5 VWC2L YWHAG ZDHHC22 Fallopian Tube Female 40-49 Up ADAMTS1 ADAMTS3 ADGRG4 ADRB3 ALX1 ATP8B4 BOC BTG2 CCDC71L CNGB3 CRISPLD2 CSRNP1 EGR1 EGR3 EMX2 FOS FOSB GAS1 GATA2 GATA5 GMNC HOXA2 HOXA3 HOXA5 HOXA6 HOXC5 IER2 IGFBP5 IRF2BPL JUN JUNB JUND KCND1 LCN10 LONRF2 MAMDC2 MEIS3 MYC NFKBIZ NGF NR2F1 NR4A1 OR10G7 OR4C46 OR4D9 OR4X2 OR8H1 OR8H3 OSR2 OVGP1 PI15 PRAMEF26 PTGIS RAI2 RARRES1 RERG RNF122 RSPO1 SAMD11 SCGB1D4 SELE SERTM1 SLC7A8 SLITRK3 SOCS3 TCF23 TNFAIP8L3 TRANK1 TULP1 WT1 ZCCHC12 ZFP36 Bladder Female 40-49 Up ABCC4 ACER2 ALDH1B1 BAG2 BTBD16 C16ORF74 CDC42BPA CHRM3 CLEC3A COL19A1 COL24A1 CTPS1 DEFB115 DEFB116 DHRS2 EDARADD ELF3 EVX1 GATA5 GCLC GLIS1 GLP2R GPR156 HOXA13 ID1 KRTAP22-1 LRFN5 LSM11 MRGPRD MSX2 MYH11 NADK2 NCKAP1L OR10H1 OR10H2 OR13A1 OR1L1 OR1L3 OR1M1 OR4A15 OR4A5 OR4C46 OR4K17 OR51A2 OR5M11 OR5T3 OR5W2 OR6C76 OR6Q1 OR7G1 OR8H3 OR8I2 OR8K1 OR9G1 OSBPL10 P2RX1 P2RY14 PADI3 PALLD PDCL3 PEX14 PGM5 PIR PITX2 PLA2G2F PLA2G4A POU5F1 PRDM6 PTGS1 PYGB RAB23 S100P SCUBE2 SIGLEC15 SLC2A8 SLITRK6 SNX31 SSH3 STON1-GTF2A1L SYNM TACR3 TCEAL1 TEAD1 TMEM252 TPSD1 TSHZ3 TXNRD1 UBR4 UGT1A6 UGT1A8 UPK1A UPK1B UPK2 UPK3A VGLL1 WFDC10B WFDC13 ZNF552 ZNF888 ZSCAN4